Still building on candidate-gene strategy in hypertension?

Hypertension

Volumn 50, Issue 4, 2007, Pages 607-608

  Tesson, Frédérique ^a   Leenen, Frans H H ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

SODIUM CHANNEL;

DISEASE MODEL; GENE MAPPING; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC TRAIT; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HAPLOTYPE; HYPERTENSION; LINKAGE ANALYSIS; NONHUMAN; NOTE; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM;

BLOOD PRESSURE; CHLORIDE CHANNELS; EPITHELIAL SODIUM CHANNEL; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; HYPERTENSION; POLYMORPHISM, SINGLE NUCLEOTIDE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 34548845047     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.096800     Document Type: Note

References (11)

1. Büsst CJ, Scurrah KJ, Ellis JA, Harrap SB. Selective genotyping reveals association between the epithelial sodium channel γ-subunit and systolic blood pressure. Hypertension. 2007;50:672-678.
2. Chang SS, Grunder S, Hanukoglu A, Rösler A, Mathew PM, Hanukoglu I, Schild L, Lu Y, Shimkets RA, Nelson-Williams C, Rossier BC, Lifton RP. Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1. Nat Genet. 1996;12:248-253.
3. Shimkets RA, Warnock DG, Bositis CM, Nelson-Williams C, Hansson JH, Schambelan M, Gill JR, Ulick S, Milora RV, Findling JW, Canessa CM, Rossier BC, Lifton RP. Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel. Cell. 1994;79:407-414.
4. Hansson JH, Nelson-Williams C, Suzuki H, Schild L, Shimkets R, Lu Y, Canessa C, Iwasaki T, Rossier B, Lifton RP. Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome. Nat Genet. 1995;11:76-82.
5. Huang BS, Amin MS, Leenen FHH. The central role of the brain in salt-sensitive hypertension. Curr Opin Cardiol. 2006;21:295-304.
6. Chang YP, Liu X, Kim JD, Ikeda MA, Layton MR, Weder AB, Cooper RS, Kardia SL, Rao DC, Hunt SC, Luke A, Boerwinkle E, Chakravarti A. Multiple genes for essential-hypertension susceptibility on chromosome 1q. Am J Hum Genet. 2007;80:253-264.
7. Barlassina C, Dal Fiume C, Lanzani C, Manunta P, Guffanti G, Ruello A, Bianchi G, Del Vecchio L, Macciardi F, Cusi D. Common genetic variants and haplotypes in renal CLCNKA gene are associated to saltsensitive hypertension. Hum Mol Genet. 2007;16:1630-1638.
8. Newton-Cheh C, Hirschhorn JN. Genetic association studies of complex traits: design and analysis issues. Mutat Res. 2005;573:54-69.
9. Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007;447:661-678.
10. Wadman M. Genome miners rush to stake claims. Nature. 2007;447:623.
11. Probing the genetics of heart disease. Science. 2007;316:1389.