Sustained secretion of immunoglobulin by long-lived human tonsil plasma cells

American Journal of Pathology

Volumn 171, Issue 3, 2007, Pages 917-927

  Van Laar, Jacob M ^a,c   Melchers, Marc ^a,c   Teng, Y K Onno ^a,c   Van Der Zouwen, Boris ^a,c   Mohammadi, Rozbeh ^a,c   Fischer, Randy ^a   Margolis, Leonid ^b   Fitzgerald, Wendy ^b   Grivel, Jean Charles ^b   Breedveld, Ferdinand C ^c   Lipsky, Peter E ^a   Grammer, Amrie C ^a  

^a National Institute of Musculoskeletal and Skin Diseases   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN; CD19 ANTIGEN; CD27 ANTIGEN; CD38 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 6; PROTEIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL POPULATION; CELL SURVIVAL; CORRELATION FUNCTION; FUNCTIONAL STATUS; HUMAN; HUMAN TISSUE; LYMPHOID TISSUE; MICROENVIRONMENT; ORGAN CULTURE; PHENOTYPE; PLASMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPERNATANT; TONSIL CELL;

EID: 34548835748     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2007.070005     Document Type: Article

References (42)

1. Tarte K, Zhan F, De Vos J, Klein B, Shaughnessy Jr J: Gene expression profiling of plasma cells and plasmablasts: toward a better understanding of the late stages of B-cell differentiation. Blood 2003, 102:592-600
2. Hammarlund E, Lewis MW, Hansen SG, Strelow LI, Nelson JA, Sexton GJ, Hanifin JM, Slifka MK: Duration of antiviral immunity after smallpox vaccination. Nat Med 2003, 9:1131-1137
3. Manz R, Thiel A, Radbruch A: Lifetime of plasma cells in the bone marrow. Nature 1997, 388:133-134
4. Sze DM, Toellner KM, Garcia de Vinuesa C, Taylor D, MacLennan IC: Intrinsic constraints on plasmablast growth and extrinsic limits of plasma cell survival. J Exp Med 2000, 192:813-821
5. Slifka MK, Antia R, Whitmire JK, Ahmed R: Humoral immunity due to long-lived plasma cells. Immunity 1998, 8:363-372
6. Minges Wols HA, Underhill GH, Kansas GS, Witte PL: The role of bone marrow-derived stromal cells in the maintenance of plasma cell longevity. J Immunol 2002, 169:4213-4221
7. Cassese G, Arce S, Hauser AE, Lehnen K, Moewes B, Mostarac M, Muehlinghaus G, Szyska M, Radbruch A, Manz RA: Plasma cell survival is mediated by synergistic effects of cytokines and adhesion-dependent signals. J Immunol 2003, 171:1684-1690
8. Gorelik L, Gilbride K, Dobles M, Kalled SL, Zandman D, Scott ML: Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells. J Exp Med 2003, 198:937-945
9. + tonsillar plasma cells are rescued from apoptosis by bone marrow fibroblasts. J Exp Med 1996, 183:227-236
10. Brieva JA, Roldan E, Rodriguez C, Navas G: Human tonsil blood and bone marrow in vivo-induced B cells capable of spontaneous and high-rate immunoglobulin secretion in vitro: differences in the requirements for factors and for adherent and for bone marrow stromal cells, as well as distinctive adhesion molecule expression. Eur J Immunol 1994, 24:362-366
11. Roldán E, Garcia-Pardo A, Brieva J: VLA-4 fibronectin interaction is required for the terminal differentiation of human bone marrow cells capable of spontaneous and high rate immunoglobulin secretion. J Exp Med 1992, 175:1739-1747
12. Kawano M, Mihara K, Huang N, Tsujimoto T, Kuramoto A: Differentiation of early plasma cells on bone marrow stromal cells requires interleukin-6 for escaping from apoptosis. Blood 1995, 85:487-494
13. Morimoto S, Kanno Y, Tanaka Y, Tokano Y, Hashimoto H, Jacquot S, Morimoto C, Schlossman SF, Yagita H, Okumura K, Kobata T: CD134L engagement enhances human B cell Ig production: CD154/CD40, CD70/CD27, and CD134/CD134L interactions coordinately regulate T cell-dependent B cell responses. J Immunol 2000, 164:4097-4104
14. Ray RJ, Stoddart A, Pennycook JL, Huner HO, Furlonger C, Wu GE, Paige CJ: Stromal cell-independent maturation of IL-7-responsive pro-B cells. J Immunol 1998, 160:5886-5897
15. Van Driel M, Gunthert U, van Kessel AC, Joling P, Stauder R, Lokhorst HM, Bloem AC: CD44 variant isoforms are involved in plasma cell adhesion to bone marrow stromal cells. Leukemia 2002, 16:135-143
16. Agematsu K, Kobata T, Yang FC, Nakazawa T, Fukushima K, Kitahara M, Mori T, Sugita K, Morimoto C, Komiyama A: CD27/CD70 interaction directly drives B cell IgG and IgM synthesis. Eur J Immunol 1995, 25:2825-2829
17. Merville P, Dechanet J, Grouard G, Durand I, Banchereau J: T cell-induced B cell blasts differentiate into plasma cells when cultured on bone marrow stroma with IL-3 and IL-10. Int Immunol 1995, 7:635-643
18. Skibinski G, Skibinska A, James K: Tonsil stromal cell lines expressing follicular dendritic cell-like properties - isolation, characterization and interaction with B lymphocytes. Biochem Soc Trans 1997, 25:233S
19. Rodriguez C, Roldan E, Navas G, Brieva JA: Essential role of tumor necrosis factor-alpha in the differentiation of human tonsil in vivo induced B cells capable of spontaneous and high-rate immunoglobulin secretion. Eur J Immunol 1993, 23:1160-1164
20. Ellyard Jl, Avery DT, Mackay CR, Tangye SG: Contribution of stromal cells to the migration, function and retention of plasma cells in human spleen: potential roles of CXCL12, IL-6 and CD54. Eur J Immunol 2005, 35:699-708
21. Shapiro-Shelef M, Calame K: Regulation of plasma-cell development. Nat Rev Immunol 2005, 5:230-242
22. Medina F, Segundo C, Campos-Caro A, González-García I, Brieva JA: The heterogeneity shown by human plasma cells from tonsil, blood, and bone marrow reveals graded stages of increasing maturity, but local profiles of adhesion molecule expression. Blood 2002, 99:2154-2161
23. + T cell depletion and virus syncytium-inducing/non-syncytium-inducing phenotype in histocultures inoculated with laboratory strains and patient isolates of HIV type 1. AIDS Res Hum Retroviruses 1997, 13:461-471
24. Terstappen LW, Johnsen S, Segers-Nolten IM, Loken MR: Identification and characterization of plasma cells in normal human bone marrow by high-resolution flow cytometry. Blood 1990, 76:1739-1747
25. Grammer AC, McFarland RD, Heaney J, Darnell BF, Lipsky PE: Expression, regulation, and function of B cell-expressed CD154 in germinal centers. J Immunol 1999, 163:4150-4159
26. Hesse MD, Karulin AY, Boehm BO, Lehmann PV, Tary-Lehmann M: A T cell clone's avidity is a function of its activation state. J Immunol 2001, 167:1353-1361
27. Holt PG, Sedgwick JD, Stewart GA, O'Leary C, Krska K: ELISA plaque assay for the detection of antibody secreting cells: observations on the nature of the solid phase and on variations in plaque diameter. J Immunol Methods 1984, 74:1-7
28. Angelin-Duclos C, Cattoretti G, Lin KL, Calame K: Commitment of B lymphocytes to a plasma cell fate is associated with Blimp-1 expression in vivo. J Immunol 2000, 165:5462-5471
29. Shapiro-Shelef M, Lin KI, Savitsky D, Liao J, Calame K: Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow. J Exp Med 2005, 202:1471-1476
30. Kallies A, Hasbold J, Tarlington DM, Dietrich W, Corcoran LM, Hodgkin PD, Nutt SL: Plasma cell ontogeny defined by quantitative changes in Blimp-1 expression. J Exp Med 2004, 200:967-977
31. Shaffer AL, Shapiro-Shelef M, Iwakoshi NN, Lee AH, Qian SB, Zhao H, Yu X, Yang L, Tan BK, Rosenwald A, Hurt EM, Petroulakis E, Sonenberg N, Yewdell JW, Calame K, Glimcher LH, Staudt LM: XBP1, downstream of Blimp1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 2004, 21:81-93
32. Lu R, Medina KL, Lancki DW, Singh H: IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev 2003, 17:1703-1708
33. Klein U, Casola S, Cattoretti G, Shen Q, Lia M, Mo T, Ludwig T, Rajewsky K, Dalla-Favera R: Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination. Nat Immunol 2006, 7:773-782
34. Vernino L, McAnally LM, Ramberg J, Lipsky PE: Generation of nondividing high rate Ig-secreting plasma cells in cultures of human B cells stimulated with anti-CD3-activated T cells. J Immunol 1992, 148:404-410
35. Bosseloir A, Hooghe-Peters EL, Heinen E, Cormann N, Kinet-Denoel C, Vanhaelst L, Simar L: Localization of interleukin 6 mRNA in human tonsils by in situ hybridization. Eur J Immunol 1989, 19:2379-2381
36. Lisignoli G, Pozzi C, Toneguzzi S, Tomassetti M, Monaco MC, Fachini A: Different pattern of cytokine production and mRNA expression by lymphoid and non-lymphoid cells isolated from human palatine tonsil. Int J Clin Lab Res 1998, 28:23-28
37. Clark EA, Grabstein KH, Shu GL: Cultured human follicular dendritic cells. Growth characteristics and interactions with B lymphocytes. J Immunol 1992, 148:3327-3335
38. Jarvis LJ, LeBien TW: Stimulation of human bone marrow stromal cell tyrosine kinases and IL-6 production by contact with B lymphocytes. J Immunol 1995, 155:2359-2368
39. Margolis LB, Fitzgerald W, Glushakova S, Hatfill S, Amichay N, Baibakov B, Zimmerberg J: Lymphocyte trafficking and HIV infection of human lymphoid tissue in a rotating wall vessel bioreactor. AIDS Res Hum Retroviruses 1997, 13:1411-1420
40. Brandtzaeg P: Immunology of tonsils and adenoids: everything the ENT surgeon needs to know. Int J Pediatr Otorhinolaryngol 2003, 67(Suppl 1):S69-S76
41. Hoyer BF, Moser K, Hauser AE, Peddinghaus A, Voigt C, Eilat D, Radbruch A, Hiepe F, Manz RA: Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice. J Exp Med 2004, 199:1577-1584
42. - plasma cells in human secondary lymphoid tissue. Blood 2007, 109:4856-4864