NO donors. Part 16: Investigations on structure-activity relationships of organic mononitrates reveal 2-nitrooxyethylammoniumnitrate as a high potent vasodilator

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 21, 2007, Pages 5881-5885

  Koenig, Andreas ^a   Roegler, Carolin ^a   Lange, Kathrin ^a   Daiber, Andreas ^b   Glusa, Erika ^a   Lehmann, Jochen ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Organic nitrates; Structure activity relationships; Vasorelaxation

Indexed keywords

2 NITROOXYETHYLAMMONIUM NITRATE; NITRIC ACID DERIVATIVE; NITRIC OXIDE DONOR; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CORRELATION ANALYSIS; DRUG POTENCY; DRUG STRUCTURE; IN VITRO STUDY; LIPOPHILICITY; MOLECULAR MODEL; PULMONARY ARTERY; STRUCTURE ACTIVITY RELATION; SWINE; VASODILATATION;

NITRATES; NITRIC OXIDE DONORS; QUATERNARY AMMONIUM COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP; VASODILATOR AGENTS;

SUS;

EID: 34548830173     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.08.046     Document Type: Article

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