메뉴 건너뛰기




Volumn 14, Issue 10, 2007, Pages 946-951

Effects of phosphodiesterase type 5 inhibitor on the contractility of prostate tissues and urethral pressure responses in a rat model of benign prostate hyperplasia

Author keywords

Benign prostatic hyperplasia; DA 8159; Intraurethral pressure; Lower urinary tract symptoms; Phosphodiesterase 5 inhibitor

Indexed keywords

ESTRADIOL; PHOSPHODIESTERASE V INHIBITOR; STEROID HORMONE; TESTOSTERONE; UDENAFIL;

EID: 34548795965     PISSN: 09198172     EISSN: 14422042     Source Type: Journal    
DOI: 10.1111/j.1442-2042.2007.01874.x     Document Type: Article
Times cited : (27)

References (29)
  • 1
    • 3142649076 scopus 로고    scopus 로고
    • Lower urinary tract symptoms (LUTS) and sexual function in both sexes
    • Hansen BL. Lower urinary tract symptoms (LUTS) and sexual function in both sexes. Eur. Urol. 2004 46 : 229 34.
    • (2004) Eur. Urol. , vol.46 , pp. 229-34
    • Hansen, B.L.1
  • 2
    • 0028812323 scopus 로고
    • Impact of symptoms of prostatism on level of bother and quality of life of men in the French community
    • Sagnier PP, MacFarlane G, Teillac P, Botto H, Richard F, Boyle P. Impact of symptoms of prostatism on level of bother and quality of life of men in the French community. J. Urol. 1995 153 : 669 73.
    • (1995) J. Urol. , vol.153 , pp. 669-73
    • Sagnier, P.P.1    MacFarlane, G.2    Teillac, P.3    Botto, H.4    Richard, F.5    Boyle, P.6
  • 4
    • 0028131343 scopus 로고
    • Experimental studies on effect on nitric oxide on the internal urethral relaxation in anesthetized rats
    • Kawahara T. Experimental studies on effect on nitric oxide on the internal urethral relaxation in anesthetized rats. Nippon Hinyokika Gakkai Zasshi 1994 85 : 1124 30.
    • (1994) Nippon Hinyokika Gakkai Zasshi , vol.85 , pp. 1124-30
    • Kawahara, T.1
  • 6
    • 0032544776 scopus 로고    scopus 로고
    • The possible effect of nitric oxide on relaxation and noradrenaline release in the isolated rabbit urethra
    • Yoshida M, Akaike T, Inadome A et al. The possible effect of nitric oxide on relaxation and noradrenaline release in the isolated rabbit urethra. Eur. J. Pharmacol. 1998 357 : 213 19.
    • (1998) Eur. J. Pharmacol. , vol.357 , pp. 213-19
    • Yoshida, M.1    Akaike, T.2    Inadome, A.3
  • 7
    • 1542540005 scopus 로고    scopus 로고
    • A review of the L-arginine - Nitric oxide - Guanylate cyclase pathway as a mediator of lower urinary tract physiology and symptoms
    • Stothers L, Laher I, Christ GT. A review of the L-arginine - nitric oxide - guanylate cyclase pathway as a mediator of lower urinary tract physiology and symptoms. Can. J. Urol. 2003 10 : 1971 80.
    • (2003) Can. J. Urol. , vol.10 , pp. 1971-80
    • Stothers, L.1    Laher, I.2    Christ, G.T.3
  • 8
    • 0027296453 scopus 로고
    • Nitric oxide synthase in pig lower urinary tract: Immunohistochemistry, NADPH diaphorase histochemistry and functional effects
    • Persson K, Alm P, Johansson K, Larsson B, Andersson KE. Nitric oxide synthase in pig lower urinary tract: immunohistochemistry, NADPH diaphorase histochemistry and functional effects. Br. J. Pharmacol. 1993 110 : 521 30.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 521-30
    • Persson, K.1    Alm, P.2    Johansson, K.3    Larsson, B.4    Andersson, K.E.5
  • 9
    • 0028674343 scopus 로고
    • Localization of nitric oxide synthase activity in the human lower urinary tract and its correlation with neuroeffector responses
    • Ehren I, Iversen H, Jansson O, Adolfsson J, Wiklund NP. Localization of nitric oxide synthase activity in the human lower urinary tract and its correlation with neuroeffector responses. Urology 1994 44 : 683 7.
    • (1994) Urology , vol.44 , pp. 683-7
    • Ehren, I.1    Iversen, H.2    Jansson, O.3    Adolfsson, J.4    Wiklund, N.P.5
  • 12
    • 17144469078 scopus 로고    scopus 로고
    • Effect of an integral suspension of Lepidium latifolium on prostate hyperplasia in rats
    • Martinez Caballero S, Carricajo Fernandez C, Perez-Fernandez R. Effect of an integral suspension of Lepidium latifolium on prostate hyperplasia in rats. Fitoterapia 2004 75 : 187 91.
    • (2004) Fitoterapia , vol.75 , pp. 187-91
    • Martinez Caballero, S.1    Carricajo Fernandez, C.2    Perez-Fernandez, R.3
  • 13
    • 0036859528 scopus 로고    scopus 로고
    • Method for simultaneous recording of the prostatic contractile and urethral pressure responses in anesthetized rats and the effects of tamsulosin
    • Kontani H, Shiraoya C. Method for simultaneous recording of the prostatic contractile and urethral pressure responses in anesthetized rats and the effects of tamsulosin. Jpn. J. Pharmacol. 2002 90 : 281 90.
    • (2002) Jpn. J. Pharmacol. , vol.90 , pp. 281-90
    • Kontani, H.1    Shiraoya, C.2
  • 14
    • 0034066949 scopus 로고    scopus 로고
    • Sex differences in urethral pressure response to electrical stimulation of the hypogastric nerves in rats
    • Kontani H, Shiraoya C. Sex differences in urethral pressure response to electrical stimulation of the hypogastric nerves in rats. J. Urol. 2000 163 : 1364 8.
    • (2000) J. Urol. , vol.163 , pp. 1364-8
    • Kontani, H.1    Shiraoya, C.2
  • 15
    • 0025688682 scopus 로고
    • Effect of anti-androgen (TZP-4238) on steroid-induced canine prostatic hyperplasia. Light and electron microscopic investigations
    • Murakoshi M, Inada R, Makino M et al. Effect of anti-androgen (TZP-4238) on steroid-induced canine prostatic hyperplasia. Light and electron microscopic investigations. Acta Pathol. Jpn. 1990 40 : 871 9.
    • (1990) Acta Pathol. Jpn. , vol.40 , pp. 871-9
    • Murakoshi, M.1    Inada, R.2    Makino, M.3
  • 16
    • 0027159536 scopus 로고
    • Effects of testosterone, and testosterone plus estrogen, in the castrated rat ventral prostate - Histopathological and immunocytochemical studies
    • Murakoshi M, Tagawa M, Inada R, Suzuki M. Effects of testosterone, and testosterone plus estrogen, in the castrated rat ventral prostate - histopathological and immunocytochemical studies. Tokai J. Exp. Clin. Med. 1992 17 : 133 7.
    • (1992) Tokai J. Exp. Clin. Med. , vol.17 , pp. 133-7
    • Murakoshi, M.1    Tagawa, M.2    Inada, R.3    Suzuki, M.4
  • 17
    • 0023921533 scopus 로고
    • Sex-hormone-induced inflammation and fibromuscular proliferation in the rat lateral prostate
    • Robinette CL. Sex-hormone-induced inflammation and fibromuscular proliferation in the rat lateral prostate. Prostate 1988 12 : 271 86.
    • (1988) Prostate , vol.12 , pp. 271-86
    • Robinette, C.L.1
  • 18
    • 0027370870 scopus 로고
    • Inhibition of steroid-induced prostatic hyperplasia in rats by treatment with anti-androgen (TZP-4238)
    • Murakoshi M, Tagawa M, Inada R, Suzuki M, Mizokami A, Watanabe K. Inhibition of steroid-induced prostatic hyperplasia in rats by treatment with anti-androgen (TZP-4238). Endocr. J. 1993 40 : 479 88.
    • (1993) Endocr. J. , vol.40 , pp. 479-88
    • Murakoshi, M.1    Tagawa, M.2    Inada, R.3    Suzuki, M.4    Mizokami, A.5    Watanabe, K.6
  • 19
    • 0028169071 scopus 로고
    • Non-adrenergic, non-cholinergic relaxation and levels of cyclic nucleotides in rabbit lower urinary tract
    • Persson K, Andersson KE. Non-adrenergic, non-cholinergic relaxation and levels of cyclic nucleotides in rabbit lower urinary tract. Eur. J. Pharmacol. 1994 268 : 159 67.
    • (1994) Eur. J. Pharmacol. , vol.268 , pp. 159-67
    • Persson, K.1    Andersson, K.E.2
  • 20
    • 0025921705 scopus 로고
    • NG-nitro-L-arginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle
    • Dokita S, Morgan WR, Wheeler MA, Yoshida M, Latifpour J, Weiss RM. NG-nitro-L-arginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle. Life Sci. 1991 48 : 2429 36.
    • (1991) Life Sci. , vol.48 , pp. 2429-36
    • Dokita, S.1    Morgan, W.R.2    Wheeler, M.A.3    Yoshida, M.4    Latifpour, J.5    Weiss, R.M.6
  • 21
    • 0038003861 scopus 로고    scopus 로고
    • Mechanism of erectogenic effect of the selective phosphodiesterase type 5 inhibitor, DA-8159
    • Doh H, Shin CY, Son M et al. Mechanism of erectogenic effect of the selective phosphodiesterase type 5 inhibitor, DA-8159. Arch. Pharm. Res. 2002 25 : 873 8.
    • (2002) Arch. Pharm. Res. , vol.25 , pp. 873-8
    • Doh, H.1    Shin, C.Y.2    Son, M.3
  • 22
    • 31744439872 scopus 로고    scopus 로고
    • Chronic treatment of DA-8159, a new phosphodiesterase type V inhibitor, attenuates endothelial dysfunction in SHR-SP
    • Choi SM, Kim JE, Kang KK. Chronic treatment of DA-8159, a new phosphodiesterase type V inhibitor, attenuates endothelial dysfunction in SHR-SP. Life Sci. 2006 78 : 1211 16.
    • (2006) Life Sci. , vol.78 , pp. 1211-16
    • Choi, S.M.1    Kim, J.E.2    Kang, K.K.3
  • 23
    • 30744461386 scopus 로고    scopus 로고
    • The effect of DA-8159, a novel PDE5 inhibitor, on erectile function in the rat model of hypercholesterolemic erectile dysfunction
    • Kang KK, Yu JY, Yoo M, Kwon JW. The effect of DA-8159, a novel PDE5 inhibitor, on erectile function in the rat model of hypercholesterolemic erectile dysfunction. Int. J. Impot. Res. 2005 17 : 409 16.
    • (2005) Int. J. Impot. Res. , vol.17 , pp. 409-16
    • Kang, K.K.1    Yu, J.Y.2    Yoo, M.3    Kwon, J.W.4
  • 24
    • 34548106573 scopus 로고    scopus 로고
    • The positive effect of sildenafil on LUTS from BPH while treating ED
    • Ying J, Yao D, Jiang Y, Ren X, Xu M. The positive effect of sildenafil on LUTS from BPH while treating ED. Zhonghua Nan Ke Xue 2004 10 : 681 3.
    • (2004) Zhonghua Nan Ke Xue , vol.10 , pp. 681-3
    • Ying, J.1    Yao, D.2    Jiang, Y.3    Ren, X.4    Xu, M.5
  • 25
    • 15844373678 scopus 로고    scopus 로고
    • Assessment of the impact of sildenafil citrate on lower urinary tract symptoms (LUTS) in men with erectile dysfunction (ED)
    • Hopps CV, Mulhall JP. Assessment of the impact of sildenafil citrate on lower urinary tract symptoms (LUTS) in men with erectile dysfunction (ED). J. Urol. 2003 169 (Suppl 4 375.
    • (2003) J. Urol. , vol.169 , Issue.SUPPL. 4 , pp. 375
    • Hopps, C.V.1    Mulhall, J.P.2
  • 26
    • 33745244449 scopus 로고    scopus 로고
    • Lower urinary tract symptoms, benign prostatic hyperplasia, erectile dysfunction, and phosphodiesterase-5 inhibitor
    • Roehrborn CG. Lower urinary tract symptoms, benign prostatic hyperplasia, erectile dysfunction, and phosphodiesterase-5 inhibitor. Rev. Urol. 2004 6 : 121 7.
    • (2004) Rev. Urol. , vol.6 , pp. 121-7
    • Roehrborn, C.G.1
  • 27
    • 34548791491 scopus 로고    scopus 로고
    • Bahng MY, Kang KK, Ahn BO*et al. Tolerance and pharmacokinetics of single-dose DA-8159 in healthy male. Int. J. Impot. Res. 2002; 14(.): S101.
    • Bahng MY, Kang KK, Ahn BO et al. Tolerance and pharmacokinetics of single-dose DA-8159 in healthy male. Int. J. Impot. Res. 2002; 14(S3): S101.
    • , Issue.3
  • 28
    • 3943050646 scopus 로고    scopus 로고
    • DA-8159-phase I studies to investigate the safety and pharmacokinetics in healthy male Caucasian subjects
    • Amakye D, Ward J, Bryson S, Han K. DA-8159-phase I studies to investigate the safety and pharmacokinetics in healthy male Caucasian subjects. Clin. Pharmacol. Ther. 2004 75 : 86.
    • (2004) Clin. Pharmacol. Ther. , vol.75 , pp. 86
    • Amakye, D.1    Ward, J.2    Bryson, S.3    Han, K.4
  • 29
    • 3943084781 scopus 로고    scopus 로고
    • Phase 1, double-blind, placebo-controlled study in healthy male subjects to investigate the safety, tolerability, and pharmacokinetics of DA-8159
    • Padma-Nathan H, Paick JS, Ahn BO, Kang KK, Bahng MY, Kim WB. Phase 1, double-blind, placebo-controlled study in healthy male subjects to investigate the safety, tolerability, and pharmacokinetics of DA-8159. J. Urol. 2004 171 (4 S234.
    • (2004) J. Urol. , vol.171 , Issue.4
    • Padma-Nathan, H.1    Paick, J.S.2    Ahn, B.O.3    Kang, K.K.4    Bahng, M.Y.5    Kim, W.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.