-
1
-
-
34547610960
-
AAV vector integration sites in mouse hepatocellular carcinoma
-
Donsante, A, Miller, DG, Li, Y, Vogler, C, Brunt, EM, Russell, DW et al. (2007). AAV vector integration sites in mouse hepatocellular carcinoma. Science 317: 477.
-
(2007)
Science
, vol.317
, pp. 477
-
-
Donsante, A.1
Miller, D.G.2
Li, Y.3
Vogler, C.4
Brunt, E.M.5
Russell, D.W.6
-
2
-
-
14744268153
-
Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver
-
Nakai, H, Wu, X, Fuess, S, Storm, TA, Munroe, D, Montini, E et al. (2005). Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver. J Virol 79: 3606-3614.
-
(2005)
J Virol
, vol.79
, pp. 3606-3614
-
-
Nakai, H.1
Wu, X.2
Fuess, S.3
Storm, T.A.4
Munroe, D.5
Montini, E.6
-
3
-
-
23844556421
-
Large-scale analysis of adeno-associated virus vector integration sites in normal human cells
-
Miller, DG, Trobridge, GD, Petek, LM, Jacobs, MA, Kaul, R and Russell, DW (2005). Large-scale analysis of adeno-associated virus vector integration sites in normal human cells. J Virol 79: 11434-11442.
-
(2005)
J Virol
, vol.79
, pp. 11434-11442
-
-
Miller, D.G.1
Trobridge, G.D.2
Petek, L.M.3
Jacobs, M.A.4
Kaul, R.5
Russell, D.W.6
-
4
-
-
0014191684
-
Nuclear ploidy in mammalian parenchymal liver cells
-
Epstein, CJ and Gatens, EA (1967). Nuclear ploidy in mammalian parenchymal liver cells. Nature 214: 1050-1051.
-
(1967)
Nature
, vol.214
, pp. 1050-1051
-
-
Epstein, C.J.1
Gatens, E.A.2
-
5
-
-
0034960344
-
Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable river transduction in vivo
-
Nakai H, Yant, SR, Storm, TA, Fuess, S, Meuse, L and Kay, MA (2001). Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable river transduction in vivo. J Virol 75: 6969-6976.
-
(2001)
J Virol
, vol.75
, pp. 6969-6976
-
-
Nakai, H.1
Yant, S.R.2
Storm, T.A.3
Fuess, S.4
Meuse, L.5
Kay, M.A.6
-
6
-
-
0028353410
-
Replacement of diseased mouse liver by hepatic cell transplantation
-
Rhim, JA, Sandgren, EP, Degen, JL, Palmiter, RD and Brinster, RL (1994). Replacement of diseased mouse liver by hepatic cell transplantation. Science 263: 1149-1152.
-
(1994)
Science
, vol.263
, pp. 1149-1152
-
-
Rhim, J.A.1
Sandgren, E.P.2
Degen, J.L.3
Palmiter, R.D.4
Brinster, R.L.5
-
7
-
-
3042728872
-
Adeno-associated virus vectors integrate at chromosome breakage sites
-
Miller, DG, Petek, LM and Russell, DW (2004). Adeno-associated virus vectors integrate at chromosome breakage sites. Nat Genet 36 767-773.
-
(2004)
Nat Genet
, vol.36
, pp. 767-773
-
-
Miller, D.G.1
Petek, L.M.2
Russell, D.W.3
-
8
-
-
0034856864
-
Capture of DNA sequences at double-strand breaks in mammalian chromosomes
-
Lin, Y and Waldman, AS (2001). Capture of DNA sequences at double-strand breaks in mammalian chromosomes. Genetics 158: 1665-1674.
-
(2001)
Genetics
, vol.158
, pp. 1665-1674
-
-
Lin, Y.1
Waldman, A.S.2
-
9
-
-
33747046320
-
Gene targeting in vivo by adeno-associated virus vectors
-
Miller, DG, Wang, PR, Petek, LM, Hirata, RK, Sands, MS and Russell, DW (2006). Gene targeting in vivo by adeno-associated virus vectors. Nat Biotechnol 24: 1022-1026.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1022-1026
-
-
Miller, D.G.1
Wang, P.R.2
Petek, L.M.3
Hirata, R.K.4
Sands, M.S.5
Russell, D.W.6
-
10
-
-
4644253753
-
A large imprinted microRNA gene duster at the mouse Dlk1-Gt12 domain
-
Seitz, H, Royo, H, Bortolin, ML, Lin, SP, Ferguson-Smith, AC and Cavaille, J (2004). A large imprinted microRNA gene duster at the mouse Dlk1-Gt12 domain. Genome Res 14: 1741-1748.
-
(2004)
Genome Res
, vol.14
, pp. 1741-1748
-
-
Seitz, H.1
Royo, H.2
Bortolin, M.L.3
Lin, S.P.4
Ferguson-Smith, A.C.5
Cavaille, J.6
-
11
-
-
0042856381
-
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gt12 imprinted cluster on mouse chromosome 12
-
Lin, SP, Youngson, N, Takada, S, Seitz, H, Reik, W, Paulsen, M et al. (2003). Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gt12 imprinted cluster on mouse chromosome 12. Nat Genet 35, 97-102.
-
(2003)
Nat Genet
, vol.35
, pp. 97-102
-
-
Lin, S.P.1
Youngson, N.2
Takada, S.3
Seitz, H.4
Reik, W.5
Paulsen, M.6
-
12
-
-
0036208835
-
Imprinting of a small nucleolar RNA gene on mouse chromosome 12
-
Shimoda, M, Morita, S, Obata, Y, Sotomaru, Y, Kono, T and Hatada I (2002). Imprinting of a small nucleolar RNA gene on mouse chromosome 12. Genomics 79: 483-486.
-
(2002)
Genomics
, vol.79
, pp. 483-486
-
-
Shimoda, M.1
Morita, S.2
Obata, Y.3
Sotomaru, Y.4
Kono, T.5
Hatada, I.6
-
13
-
-
0033694804
-
Parental origin-specific developmental defects in mice with uniparental disomy for chromosome 12
-
Georglades, P, Watkins, M, Surani, MA and Ferguson-Smith, AC (2000). Parental origin-specific developmental defects in mice with uniparental disomy for chromosome 12. Development 127: 4719-4728.
-
(2000)
Development
, vol.127
, pp. 4719-4728
-
-
Georglades, P.1
Watkins, M.2
Surani, M.A.3
Ferguson-Smith, A.C.4
-
14
-
-
0033975096
-
Beckwith-Wiedemann syndrome: Imprinting in clusters revisited
-
Maher, ER and Reik W (2000). Beckwith-Wiedemann syndrome: Imprinting in clusters revisited. J Clin Invest 105: 247-252.
-
(2000)
J Clin Invest
, vol.105
, pp. 247-252
-
-
Maher, E.R.1
Reik, W.2
-
15
-
-
0036392059
-
DNA methylation and genomic imprinting: Insights from cancer into epigienetic mechanisms
-
Feinberg, AP, Cui, H and Ohlsson, R (2002). DNA methylation and genomic imprinting: Insights from cancer into epigienetic mechanisms. Semin Cancer Biol 12: 389-398.
-
(2002)
Semin Cancer Biol
, vol.12
, pp. 389-398
-
-
Feinberg, A.P.1
Cui, H.2
Ohlsson, R.3
-
16
-
-
0035069170
-
The callipyge mutation enhances the expression of coregulated imprinted genes in cis without affecting their imprinting status
-
Charlier, C Segers K, Karim L, Shay T, Gyapay G, Cockett N et al. (2001). The callipyge mutation enhances the expression of coregulated imprinted genes in cis without affecting their imprinting status. Nat Genet 27: 367-369.
-
(2001)
Nat Genet
, vol.27
, pp. 367-369
-
-
Charlier, C.1
Segers, K.2
Karim, L.3
Shay, T.4
Gyapay, G.5
Cockett, N.6
-
17
-
-
33644749370
-
Imprinted DLK1 is a putative tumor suppressor gene and inactivated by epimutation at the region upstream of GTL2 in human renal cell carcinoma
-
Kawakami, T, Chano, T, Minami, K, Okabe, H, Okada, Y and Okamoto, K (2006). Imprinted DLK1 is a putative tumor suppressor gene and inactivated by epimutation at the region upstream of GTL2 in human renal cell carcinoma. Hum Mol Genet 15: 821-830.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 821-830
-
-
Kawakami, T.1
Chano, T.2
Minami, K.3
Okabe, H.4
Okada, Y.5
Okamoto, K.6
-
18
-
-
18944384938
-
Epigenetic alteration at the DLK1-GTL2 imprinted domain in human neoplasia: Analysis of neuroblastoma, phaeochromocytoma and Wilms' tumour
-
Astuti, D, Latif, F, Wagner, K, Gentle, D, Cooper, WN, Catchpoole, D et al. (2005). Epigenetic alteration at the DLK1-GTL2 imprinted domain in human neoplasia: Analysis of neuroblastoma, phaeochromocytoma and Wilms' tumour. Br J Cancer 92: 1574-1580.
-
(2005)
Br J Cancer
, vol.92
, pp. 1574-1580
-
-
Astuti, D.1
Latif, F.2
Wagner, K.3
Gentle, D.4
Cooper, W.N.5
Catchpoole, D.6
-
20
-
-
30544434808
-
Characterization of three novel imprinted snoRNAs from mouse Imm gene
-
Xiao Y, Zhou, H and Qu, LH (2006). Characterization of three novel imprinted snoRNAs from mouse Imm gene. Biochem Biophys Res Commun 340: 1217-1223.
-
(2006)
Biochem Biophys Res Commun
, vol.340
, pp. 1217-1223
-
-
Xiao, Y.1
Zhou, H.2
Qu, L.H.3
-
21
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin, GA and Croce, CM (2006). MicroRNA signatures in human cancers. Nat Rev Cancer 6: 857-866.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
22
-
-
33644750115
-
miRBase, microRNA sequences, targets and gene nomenclature
-
Griffiths-Jones, S, Grocock, RJ, van Dongen, S, Bateman, A and Enright, AJ (2006). miRBase, microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 34: D140-D144.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Griffiths-Jones, S.1
Grocock, R.J.2
van Dongen, S.3
Bateman, A.4
Enright, A.J.5
-
23
-
-
0034830365
-
observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors
-
Donsante, A, Vogler, C, Muzyczka, N, Crawford, JM, Barker, J, Flotte, T et al. (2001). observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors. Gene Ther 8: 1343-1346.
-
(2001)
Gene Ther
, vol.8
, pp. 1343-1346
-
-
Donsante, A.1
Vogler, C.2
Muzyczka, N.3
Crawford, J.M.4
Barker, J.5
Flotte, T.6
-
24
-
-
34548792469
-
Long term portal vein administration of AAV-WPRE vector results in increased incidence of neoplastic disease and hepatic pathology
-
Embury, JE, Charron, CC, Poirier, AE. Zori, A, Carmichael, R, Flotte, TR et al. (2006). Long term portal vein administration of AAV-WPRE vector results in increased incidence of neoplastic disease and hepatic pathology. Mol Ther 13: S83.
-
(2006)
Mol Ther
, vol.13
-
-
Embury, J.E.1
Charron, C.C.2
Poirier, A.E.3
Zori, A.4
Carmichael, R.5
Flotte, T.R.6
-
25
-
-
34548800895
-
Adverse shRNA cytotoxicity can accelerate tumorigenesis in genetically predisposed mice
-
Grimm, D, Beer, S, Komatsubara, K, Lee, JS, Koh, S, Wang, L et al. (2007). Adverse shRNA cytotoxicity can accelerate tumorigenesis in genetically predisposed mice. Mol Ther 15: S266.
-
(2007)
Mol Ther
, vol.15
-
-
Grimm, D.1
Beer, S.2
Komatsubara, K.3
Lee, J.S.4
Koh, S.5
Wang, L.6
-
26
-
-
33745250487
-
Analysis of tumors arising in male B6C3F1 mice with and without AAV vector delivery to liver
-
Bell, P, Moscioni, AD, McCarter, RJ, Wu, D, Gao, G, Hoang, A et al. (2006). Analysis of tumors arising in male B6C3F1 mice with and without AAV vector delivery to liver. Mol Ther 14: 34-44.
-
(2006)
Mol Ther
, vol.14
, pp. 34-44
-
-
Bell, P.1
Moscioni, A.D.2
McCarter, R.J.3
Wu, D.4
Gao, G.5
Hoang, A.6
-
27
-
-
0037418258
-
Transgene produces massive overexpression of human β-glucuronidase in mice, lysosomal storage of enzyme, and strain-dependent tumors
-
Vogler, C, Galvin, N, Levy, B, Grubb, J, Jiang, J, Zhou, XY et al. (2003), Transgene produces massive overexpression of human β-glucuronidase in mice, lysosomal storage of enzyme, and strain-dependent tumors. Proc Natl Acad Sci USA 100: 2669-2673.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2669-2673
-
-
Vogler, C.1
Galvin, N.2
Levy, B.3
Grubb, J.4
Jiang, J.5
Zhou, X.Y.6
-
28
-
-
0037096916
-
Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/ Angelman syndrome region
-
Cavaille, J, Seitz, H, Paulsen, M, Ferguson-Smith, AC and Bachellerie, JP (2002). Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/ Angelman syndrome region. Hum Mol Genet 11: 1527-1538.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1527-1538
-
-
Cavaille, J.1
Seitz, H.2
Paulsen, M.3
Ferguson-Smith, A.C.4
Bachellerie, J.P.5
-
29
-
-
0141839733
-
Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver
-
Wilson, ZE, Rostami-Hodjegan, A, Burn, JL, Tooley, A, Boyle, J, Ellis, SW, et al. (2003). Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver. Br J Clin Pharmacol 56: 433-440.
-
(2003)
Br J Clin Pharmacol
, vol.56
, pp. 433-440
-
-
Wilson, Z.E.1
Rostami-Hodjegan, A.2
Burn, J.L.3
Tooley, A.4
Boyle, J.5
Ellis, S.W.6
-
30
-
-
33644820684
-
Successful transcluction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
-
Manno, CS, Pierce, GF, Arruda, VR, Glacier, B, Ragni, M, Rasko, JJ et al. (2006). Successful transcluction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response. Nat Med 12: 342-347.
-
(2006)
Nat Med
, vol.12
, pp. 342-347
-
-
Manno, C.S.1
Pierce, G.F.2
Arruda, V.R.3
Glacier, B.4
Ragni, M.5
Rasko, J.J.6
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