Anti-inflammatory activity of 21(α, β)-methylmelianodiols, novel compounds from Poncirus trifoliata Rafinesque

European Journal of Pharmacology

Volumn 572, Issue 2-3, 2007, Pages 239-248

  Zhou, Hong Yu ^a,b   Shin, Eun Myung ^a   Guo, Lian Yu ^a   Zou, Li Bo ^b   Xu, Guang Hua ^c   Lee, Seung Ho ^c   Ze, Keum Ryon ^d   Kim, Eun Kyung ^d   Kang, Sam Sik ^a   Kim, Yeong Shik ^a  

^a Seoul National University   (South Korea)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c Yeungnam University   (South Korea)

^d Korea Food and Drug Administration   (South Korea)

Author keywords

) methylmelianodiols; 21( ; Anti inflammation; Cyclooxygenase 2; In vivo activity; Inducible nitric oxide synthase; Nuclear factor B

Indexed keywords

21ALPHA METHYLMELIANODIOL; 21BETA METHYLMELIANODIOL; ACETIC ACID; CARRAGEENAN; CYCLOOXYGENASE 2; DEXAMETHASONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OLIVE OIL; PLANT EXTRACT; PONCIRUS TRIFOLIATA EXTRACT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG ISOLATION; DRUG STRUCTURE; MACROPHAGE; MOUSE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; TRIFOLIATE ORANGE;

ACETIC ACID; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CAPILLARY PERMEABILITY; CARRAGEENAN; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE 2; EDEMA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PONCIRUS; RNA, MESSENGER; STEREOISOMERISM; TRANSCRIPTION, GENETIC; TRITERPENES;

EID: 34548784480     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.07.005     Document Type: Article

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