Tyrosinase biosynthesis and trafficking in adult human retinal pigment epithelial cells

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 245, Issue 10, 2007, Pages 1495-1505

  Julien, Sylvie ^a   Kociok, Norbert ^b   Kreppel, Florian ^c   Kopitz, Jürgen ^d   Kochanek, Stefan ^c   Biesemeier, Antje ^a   Blitgen Heinecke, Petra ^a   Heiduschka, Peter ^a   Schraermeyer, Ulrich ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b Cell Center Cologne   (Germany)

^c UNIVERSITY OF ULM   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Biosynthesis; Human; Phagosome; Retinal pigment epithelium; Tyrosinase

Indexed keywords

ENZYME ANTIBODY; LATEX; MESSENGER RNA; MONOPHENOL MONOOXYGENASE; RHODOPSIN; TYROSINE 3 MONOOXYGENASE;

ADULT; ARTICLE; CATTLE; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME LOCALIZATION; ENZYME SYNTHESIS; EPITHELIUM CELL; HISTOCHEMISTRY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; INCUBATION TIME; INTRACELLULAR TRANSPORT; MELANOGENESIS; NONHUMAN; PHAGOCYTOSIS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RETINA ROD OUTER SEGMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION;

ANIMALS; BIOLOGICAL TRANSPORT; CATTLE; CELLS, CULTURED; DIHYDROXYPHENYLALANINE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MIDDLE AGED; MONOPHENOL MONOOXYGENASE; PHAGOCYTOSIS; PIGMENT EPITHELIUM OF EYE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHODOPSIN; RNA, MESSENGER; ROD OUTER SEGMENTS; TRANSFECTION; TYROSINE 3-MONOOXYGENASE;

EID: 34548761359     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-007-0543-3     Document Type: Article

References (56)

1. Abul-Hassan K, Walmsley R, Tombran-Tink J, Boulton M (2000) Regulation of tyrosinase expression and activity in cultured human retinal pigment epithelial cells. Pigment Cell Res 13:436-441
2. Aronson JF (1983) Human retinal pigment cell culture. In Vitro 19:642-650
3. Basu PK, Sarkar P, Menon I, Carre F, Persad S (1983) Bovine retinal pigment epithelial cells cultured in vitro: Growth characteristics, morphology, chromosomes, phagocytosis ability, tyrosinase activity and effect of freezing. Exp Eye Res 36:671-683
4. Brichard V, Van Pel A, Wolfel C, De Plaen E, Lethe B, Coulie P, Boon T (1993) The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J Exp Med 178:489-495
5. Carr RE, Siegel IM (1979) The retinal pigment epithelium in ocular albinism. In: KM Zinn, Marmor MF (eds) The retinal pigment epithelium. Harvard University Press, Cambridge, MA, pp 413-423
6. Chowers I, Kim Y, Farkas RH, Gunatilaka TL, Hackam AS, Campochiaro PA, Finnemann SC, Zack DJ (2004) Changes in retinal pigment epithelial gene expression induced by rod outer segment uptake. Invest Ophthalmol Vis Sci 45:2098-2106
7. Cuomo M, Nicotra MR, Apollonj C, Fraioli R, Giacomini P, Natali PG (1991) Production and characterization of the murine monoclonal antibody 2G10 to a human T4-tyrosinase epitope. J Invest Dermatol 96:446-451
8. Diment S, Eidelman M, Rodriguez GM, Orlow SJ (1995) Lysosomal hydrolases are present in melanosomes and are elevated in melanizing cells. J Biol Chem 270:4213-4215
9. Dorey CK, Khouri GG, Syniuta LA, Curran SA, Weiter JJ (1989) Superoxide production by porcine retinal pigment epithelium in vitro. Invest Ophthalmol Vis Sci 30:1047-1054
10. Dorey CK, Torres X, Swart T (1990) Evidence of melanogenesis in porcine retinal pigment epithelial cells in vitro. Exp Eye Res 50:1-10
11. Dryja TP, O'Neil-Dryja M, Pawelek JM, Albert DM (1978) Demonstration of tyrosinase in the adult bovine uveal tract and retinal pigment epithelium. Invest Ophthalmol Vis Sci 17:511-514
12. Ershov AV, Lukiw WJ, Bazan NG (1996) NG Selective transcription factor induction in retinal pigment epithelial cells during photoreceptor phagocytosis. J Biol Chem 271:28458-28462
13. Ferguson CA, Kidson SH (1997) The regulation of tyrosinase gene transcription. Pigment Cell Res 10:127-138
14. Friedman DS, Katz J, Bressler NM, Rahmani B, Tielsch JM (1999) Racial differences in the prevalence of age-related macular degeneration: The Baltimore Eye Survey. Ophthalmology 106:1049-1055
15. Gomez Sarosi LA, Rieber MS, Rieber M (2003) Hydrogen peroxide increases a 55-kDa tyrosinase concomitantly with induction of p53-dependent p21 waf1 expression and a greater Bax/Bcl-2 ratio in pigmented melanoma. Biochem Biophys Res Commun 312:355-359
16. Hearing VJ (2005) Biogenesis of pigment granules: A sensitive way to regulate melanocyte function. J Dermatol Sci 37:3-14
17. Herman KG, Steinberg RH (1982) Melanosome metabolism in the retinal pigmented epithelium of the opossum. Cell Tissue Res 227:485-507
18. Higashi Y, Asanuma M, Miyazaki I, Ogawa N (2000) Inhibition of tyrosinase reduces cell viability in catecholaminergic neuronal cells. J Neurochem 75:1771-1774
19. Karg E, Odh G, Wittbjer A, Rosengren E, Rorsman H (1993) Hydrogen peroxide as an inducer of elevated tyrosinase level in melanoma cells. J Invest Dermatol 100:209S-213S
20. Kitano Y, Hu F (1970) DNA, RNA, and protein synthesis of pigment cells in culture. J Invest Dermatol 54:463-471
21. Korner A, Pawelek J (1982) Mammalian tyrosinase catalyzes three reactions in the biosynthesis of melanin. Science 217:1163-1165
22. Kreppel F, Biermann V, Kochanek S, Schiedner G (2002) A DNA-based method to assay total and infectious particle contents and helper virus contamination in high-capacity adenoviral vector preparations. Hum Gene Ther 13:1151-1156
23. LaVail MM (1980) Circadian nature of rod outer segment disc shedding in the rat. Invest Ophthalmol Vis Sci 19:407-411
24. Lerch K (1987) Monophenol monooxygenase from Neurospora crassa. Methods Enzymol 142:165-169
25. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
26. Mallick S, Singh SK, Sarkar C, Saha B, Bhadra R (2005) Human placental lipid induces melanogenesis by increasing the expression of tyrosinase and its related proteins in vitro. Pigment Cell Res 18:25-33
27. Marks MS, Seabra MC (2001) The melanosome: Membrane dynamics in black and white. Nat Rev Mol Cell Biol 2:738-748
28. Mirica LM, Vance M, Rudd DJ, Hedman B, Hodgson KO, Solomon EI, Stack TD (2005) Tyrosinase reactivity in a model complex: An alternative hydroxylation mechanism. Science 308:1890-1892
29. Miyamoto M, Fitzpatrick TB (1957) On the nature of pigment in retinal pigment epithelium. Science 126:449-450
30. Morrison TB, Weiss JJ, Wittwer CT (1998) Quantification of low-copy transcripts by continuous SYBR Green monitoring during amplification. Biotechniques 24:954-958, 960, 962
31. Naeyaert JM, Eller M, Gordon PR, Park HY, Gilchrest BA (1991) Pigment content of cultured human melanocytes does not correlate with tyrosinase message level. Br J Dermatol 125:297-303
32. Nakagawa H, Rhodes AR, Momtaz T, Fitzpatrick TB (1984) Morphologic alterations of epidermal melanocytes and melanosomes in PUVA lentigines: a comparative ultrastructural investigation of lentigines induced by PUVA and sunlight. J Invest Dermatol 82:101-107
33. Novikoff AB, Leuenberger PM, Novikoff PM, Quintana N (1979) Retinal pigment epithelium. Interrelations of endoplasmic reticulum and melanolysosomes in the black mouse and its beige mutant. Lab Invest 40:155-165
34. Orlow SJ (1995) Melanosomes are specialized members of the lysosomal lineage of organelles. J Invest Dermatol 105:3-7
35. Raposo G, Marks MS (2002) The dark side of lysosome-related organelles: specialization of the endocytic pathway for melanosome biogenesis. Traffic 3:237-248
36. Rungta D, Corn TD, Fuller BB (1996) Regulation of tyrosinase mRNA in mouse melanoma cells by alpha-melanocyte-stimulating hormone. J Invest Dermatol 107:689-693
37. Sarna T (1992) Properties and function of the ocular melanin-a photobiophysical view. J Photochem Photobiol B 12:215-258
38. Schiedner G, Hertel S, Kochanek S (2000) Efficient transformation of primary human amniocytes by E1 functions of Ad5: Generation of new cell lines for adenoviral vector preparation. Hum Gene Ther 11:2105-2116
39. Schraermeyer U (1992) Evidence for melanogenesis in the retinal pigment epithelium of adult cattle and golden hamster. Comp Biochem Physiol B 103:435-442
40. Schraermeyer U (1992) Localization of peroxidase activity in the retina and the retinal pigment epithelium of the Syrian golden hamster (Mesocricetus auratus). Comp Biochem Physiol B 103:139-145
41. Schraermeyer U (1993) Does melanin turnover occur in the eyes of adult vertebrates? Pigment Cell Res 6:193-204
42. Schraermeyer U, Stieve H (1994) A newly discovered pathway of melanin formation in cultured retinal pigment epithelium of cattle. Cell Tissue Res 276:273-279
43. Schraermeyer U (1995) Transport of endocytosed material into melanin granules in cultured choroidal melanocytes of cattle-new insights into the relationship of melanosomes with lysosomes. Pigment Cell Res 8:209-214
44. Schraermeyer U, Enzmann V, Kohen L, Addicks K, Wiedemann P, Heimann K (1997) Porcine iris pigment epithelial cells can take up retinal outer segments. Exp Eye Res 65:277-287
45. Schraermeyer U, Heimann K (1999) Current understanding on the role of retinal pigment epithelium and its pigmentation. Pigment Cell Res 12:219-236
46. Schraermeyer U, Peters S, Thumann G, Kociok N, Heimann K (1999) Melanin granules of retinal pigment epithelium are connected with the lysosomal degradation pathway. Exp Eye Res 68:237-245
47. Schraermeyer U, Kopitz J, Peters S, Henke-Fahle S, Blitgen-Heinecke P, Kokkinou, D, Schwartz T, Bartz-Schmidt K-U (2006) Tyrosinase biosynthesis in adult mammalian retinal pigment epithelial cells. Exp Eye Res 83:315-321
48. Seiji M, Fitzpatrick TB, Simpson RT, Birbeck MS (1963) Chemical composition and terminology of specialized organelles (melanosomes and melanin granules) in mammalian melanocytes. Nature 197:1082-1084
49. Smith-Thomas L, Richardson P, Thody AJ, Graham A, Palmer I, Flemming L, Parsons MA, Rennie IG, MacNeil S (1996) Human ocular melanocytes and retinal pigment epithelial cells differ in their melanogenic properties in vivo and in vitro. Curr Eye Res 15:1079-1091
50. Tief K, Hahne M, Schmidt A, Beermann F (1996) Tyrosinase, the key enzyme in melanin synthesis, is expressed in murine brain. Eur J Biochem 241:12-16
51. Valverde P, Manning P, McNeil CJ, Thody AJ (1996) Activation of tyrosinase reduces the cytotoxic effects of the superoxide anion in B16 mouse melanoma cells. Pigment Cell Res 9:77-84
52. Varela JM, Stempels NA, Vanden Berghe DA, Tassignon MJ (1995) Isoenzymic patterns of tyrosinase in the rabbit choroid and retina/retinal pigment epithelium. Exp Eye Res 60:621-629
53. Weisse I (1995) Changes in the aging rat retina. Ophthalmic Res 27 Suppl 1:154-163
54. Wood JM, Schallreuter KU (1991) Studies on the reactions between human tyrosinase, superoxide anion, hydrogen peroxide and thiols. Biochim Biophys Acta 1074:378-385
55. Young RW (1978) The daily rhythm of shedding and degradation of rod and cone outer segment membranes in the chick retina. Invest Ophthalmol Vis Sci 17:105-116
56. Zareba M, Raciti MW, Henry MM, Sarna T, Burke JM (2006) Oxidative stress in ARPE-19 cultures: Do melanosomes confer cytoprotection? Free Radic Biol Med 40:87-100