Decreased hydrogen-potassium-activated ATPase (H+-K+-ATPase) expression and gastric acid secretory capacity in aged mice

Archives of Gerontology and Geriatrics

Volumn 45, Issue 3, 2007, Pages 243-252

  Kanai, Setsuko ^a   Hosoya, Hiroko ^a   Ohta, Minoru ^a   Miyasaka, Kyoko ^a  

^a TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY   (Japan)

Author keywords

Acetylcholine; Gastric acid secretion; Histamine; Hydrogen potassium activated ATPase (H+ K+ ATPase)

Indexed keywords

CARBACHOL; CYCLIC AMP; HISTAMINE; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; SODIUM CHLORIDE;

AGING; ANIMAL EXPERIMENT; ARTICLE; CALCIUM SIGNALING; CELL FUNCTION; CONTROLLED STUDY; FEMALE; MECHANICAL STIMULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STIMULATION; STOMACH ACID; STOMACH ACID SECRETION; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATASES; AGING; ANIMALS; BLOTTING, WESTERN; CARBACHOL; FEMALE; GASTRIC ACID; HISTAMINE; MICE; MICE, INBRED C57BL; PARIETAL CELLS, GASTRIC;

MUS;

EID: 34548746940     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archger.2006.10.014     Document Type: Article

References (27)

1. Bannister J.J., Abouzekry L., and Read N.W. Effect of aging on anorectal function. Gut 28 (1987) 353-357
2. Campbell V.W., and Yamada T. Acid secretagogue-induced stimulation of gastric parietal cell gene expression. J. Biol. Chem. 264 (1989) 11381-11386
3. Cehn D., Zhao C.M., Hakanson R., Samuelson L.C., Rehfeld J.F., and Friis-Hansen L. Altered control of gastric acid secretion in gastrin-cholecystokinin double mutant mice. Gastroenterology 126 (2004) 476-487
4. Connor B.A. Gastrointestinal disorders of the stomach and duodenum in the elderly. In: Gelb A.M. (Ed). Clinical Gastroenterology in the Elderly (1996), Marcel Dekker, Inc., New York 34-72
5. Friis-Hansen L., Sundler F., Li Y., Gillespie P.J., Saunders T.L., Greenson J.K., Owyang C., Rehfeld J.F., and Samuelson L.C. Impaired gastric acid secretion in gastrin-deficient mice. Am. J. Physiol. 274 (1998) G561-G568
6. +-ATPase α-subunit gene expression by helicobacter pylori. Am. J. Physiol. 278 (2000) G981-G991
7. +-ATPase activity. Am. J. Physiol. 252 (1987) G28-G32
8. Hogben C.A., Kent T.H., Woodward P.A., and Sill A.J. Quantitative histology of the gastric mucosa: man, dog, rat, guinea pig and frog. Gastroenterology 67 (1974) 1143-1154
9. Hollander D., Tarnawski A., Stachura J., and Gergely H. Morphologic changes in gastric mucosa of aging rats. Dig. Dis. Sci. 34 (1989) 1692-1700
10. Hollis J.B., and Castell D.O. Esophageal function in elderly men. A new look at "presbyesophagus". Ann. Intern. Med. 80 (1974) 371-374
11. Jones C.M., Callaghan J.M., Gleeson P.A., Mori Y., Masuda T., and Toh B.H. The parietal cell autoantibodies recognized in neonatal thymectomy-induced murine gastritis are the α and β subunits of the gastric proton pump. Gastroenterology 101 (1991) 287-294
12. Khalil T., Singh P., Fujimura M., Courtney M., Townsend Jr. C.M., Greeley, and Thompson J.C. Effect of aging on gastric acid secretion, serum gastrin, and antral gastrin content in rats. Dig. Dis. Sci. 33 (1988) 1544-1548
13. Khanna P.B., Davies I., and Faragher E.B. Age-related changes in the stomach of the laboratory mouse: a quantitative morphological study. Age Ageing 17 (1988) 257-264
14. Loewy A.D., Franklin M.F., and Haxhiu M.A. CNS monoamine cell groups projecting to pancreatic vagal motor neurons: a transneuronal labeling study using pseudo-rabies virus. Brain Res. 638 (1994) 248-260
15. Maitra R.S., Edgerton E.A., and Majumdar A.P.N. Gastric secretion during aging in pyloric-ligated rats and effects of pentagastrin. Exp. Gerontol. 23 (1988) 463-472
16. Majumdar A.P.N., Jasti S., Hatfield J.S., Tureaud J., and Fligiel S.E.G. Morphological and biochemical changes in gastric mucosa of aging rats. Dig. Dis. Sci. 35 (1990) 1364-1370
17. Moore J.G., Tweedy C., Christian P.E., and Datz F.L. Effect of age on gastric emptying of liquid-solid meals in man. Dig. Dis. Sci. 28 (1983) 340-344
18. Niedermüller H., Basota I., Strasser A., and Hofecker G. Age dependence of signal transduction and cell signaling as a major factor of intervention into the aging process. Arch. Gerontol. Geriatr. 33 (2001) 151-161
19. Noto T., Nagasaki M., and Endo T. Role of vagus nerves and gastrin in the gastric phase of acid secretion in male anesthetized rats. Am. J. Physiol. 272 (1997) G335-G339
20. O'Dorisio M.S. Neuropeptides and gastrointestinal immunity. Am. J. Med. 81 (1986) 74-82
21. Ohta M., Tanaka Y., Masuda M., Miyasaka K., and Funakoshi A. Impaired release of cholecystokinin (CCK) from synaptosomes in old rats. Neurosci. Lett. 198 (1995) 161-164
22. Phillips R.J., Kieffer E.J., and Powley T.L. Aging of the myenteric plexus: neuronal loss is specific to cholinergic neurons. Auton. Neurosci. 106 (2003) 69-83
23. Rabon E., Cuppoletty J., Malinowska D., Smolka A., Helander H.F., Mendlein J., and Sachs G. Proton secretion by the gastric parietal cell. J. Exp. Biol. 106 (1983) 119-133
24. Tanaka S., Hamada K., Yamada N., Sugita Y., Tonai S., Hunyaday B., Palkovits M., Falus A., Watanabe T., Okabe S., Ohtsu H., Ichikawa A., and Nagy A. Gastric acid secretion in l-histidine decarboxylase-deficient mice. Gastroenterology 122 (2002) 145-155
25. Wiley J.W. Aging and neural control of the GI tract III. Senescent enteric nervous system: lessons from extraintestinal sites and nonmammalian species. Am. J. Physiol. 283 (2002) G1020-G1026
26. +-ATPase α2-subunit gene. Am. J. Physiol. 287 (2004) C903-C911
27. +-ATPase α 2-subunit gene. J. Am. Soc. Nephrol. 12 (2001) 2554-2564