Genetic engineering of the heme pocket in human serum albumin: Modulation of O2 binding of iron protoporphyrin IX by variation of distal amino acids

Journal of the American Chemical Society

Volumn 129, Issue 36, 2007, Pages 11286-11295

  Komatsu, Teruyuki ^a,b   Nakagawa, Akito ^a   Zunszain, Patricia A ^c   Curry, Stephen ^c   Tsuchida, Eishun ^a  

^a WASEDA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BLOOD; CHARACTERIZATION; HEMOGLOBIN; HYDROPHOBICITY; MUTAGENESIS; PORPHYRINS;

HEME GROUP; HEMOPROTEINS; HUMAN SERUM ALBUMIN; PROTOPORPHYRINS; RED BLOOD CELLS;

GENETIC ENGINEERING;

ALBUMIN; AMINO ACID DERIVATIVE; ARGININE; GLYCINE; HEMOPROTEIN; HISTONE; IRON; LEUCINE; OXYGEN; PHENYLALANINE; PROTOPORPHYRIN; RECOMBINANT PROTEIN;

ARTICLE; AUTOOXIDATION; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; GENE MUTATION; GENETIC ENGINEERING; HUMAN; HYDROPHOBICITY; KINETICS; LIGAND BINDING; MODULATION; OXYGEN AFFINITY; PHYSICAL CHEMISTRY; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; GENETIC ENGINEERING; HEME; HUMANS; MODELS, MOLECULAR; OXYGEN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTOPORPHYRINS; SERUM ALBUMIN;

EID: 34548737693     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja074179q     Document Type: Article

References (49)

1. (a) Muller-Eberhard, U; Grizzuti, K. Biochemistry 1971, 10, 2062-2066.
2. (b) Muller-Eberhard, U.; Morgan, W. T. Ann. N.Y. Acad. Sci. 1975, 244, 624-650.
3. Paoli, M.; Anderson, B. F.; Baker, H. M.; Morgan, W. T.; Smith, A.; Baker, E. N. Nat. Struct. Biol. 1999, 6, 926-931.
4. Tolosano, E.; Altruda, F. DNA Cell Biol. 2002, 21, 297-306.
5. Peters, T. All about Albumin: Biochemistry, Genetics and Medical Applications; Academic Press: San Diego, CA, 1996; and references therein.
6. (a) Kragh-Hansen, U. Pharmacol. Rev. 1981, 33, 17-53.
7. (b) Kragh-Hansen, U. Danish Med. Bull. 1990, 37, 57-84.
8. (a) He, X. M.; Carter, D. C. Nature 1992, 358, 209-215.
9. (b) Carter, D. C.; Ho, J. X. Adv. Protein Chem. 1994, 45, 153-203.
10. (a) Curry, S.; Madelkow, H.; Brick, P.; Franks, N. Nat. Struct. Biol. 1998, 5, 827-835.
11. (b) Bhattacharya, A. A.; Grune, T.; Curry, S. J. Mol. Biol. 2000, 303, 721-732.
12. Wardell, M.; Wang, Z.; Ho, J. X.; Robert, J.; Ruker, F.; Rubel, J.; Carter, D. C. Biochem. Biophys. Res. Commun. 2002, 291, 813-819.
13. Zunszain, P. A.; Ghuman, J.; Komatsu, T.; Tsuchida, E.; Curry, S. BMC Struct. Biol. 2003, 3, 6.
14. Monzani, E.; Bonafè, B.; Fallarini, A.; Redaelli, C.; Casella, L.; Minchiotti, L.; Galliano, M. Biochim. Biophys. Acta. 2001, 1547, 302-312.
15. (a) Komatsu, T.; Ohmichi, N.; Zunszain, P. A.; Curry, S.; Tsuchida, E. J. Am. Chem. Soc. 2004, 126, 14304-14305.
16. (b) Komatsu, T.; Ohmichi, N.; Nakagawa, A.; Zunszain, P. A.; Curry, S.; Tsuchida, E. J. Am. Chem. Soc. 2005, 127, 15933-15942.
17. Phillips, S. E. V.; Schoenborn, B. P. Nature 1981, 292, 81-82.
18. (a) Olson, J. S.; Mathews, A. J.; Rohlfs, R. J.; Springer, B. A.; Egeberg, K. D.; Sligar, S. G.; Tame, J.; Renaud, J.-P.; Nagai, K. Nature 1988, 336, 265-266.
19. (b) Rohlfs, R.; Mathews, A. J.; Carver, T. E.; Olson, J. S.; Springer, B. A.; Egeberg, K. D.; Sligar, S. G. J. Biol. Chem. 1990, 265, 3168-3176.
20. (c) Springer B. A.; Sligar, S. G.; Olson, J. S.; Phillips, G. N., Jr. Chem. Rev. 1994, 94, 699-714.
21. Momenteau, M.; Reed, C. A. Chem. Rev. 1994, 94, 659-698.
22. Collman, J. P.; Fu, L. Acc. Chem. Res. 1999, 32, 455-463.
23. (a) Collman, J. P.; Gagne, R. R.; Halbert, T. R.; Marchou, J.-C.; Reed. C. A. J. Am. Chem. Soc. 1973, 95, 7869-7870.
24. (b) Collman, J. P.; Gagne, R. R.; Reed, C. A.; Halbert, T. R.; Lang, G.; Robinson, W. T. J. Am. Chem. Soc. 1975, 97, 1427-1439.
25. (c) Collman, J. P.; Brauman, J. I.; Iverson, B. L.; Sessler, J. L.; Morris, R. M.; Gibson, Q. H. J. Am. Chem. Soc. 1983, 105, 3052-3064.
26. Momenteau, M.; Lavalette, D. J. Chem. Soc., Chem. Commun. 1982, 341-343.
27. (a) Komatsu, T.; Hasegawa, E.; Nishide, H.; Tsuchida, E. J. Chem. Soc, Chem. Commun. 1990, 66-68.
28. (b) Tsuchida, E.; Komatsu, T.; Arai, K.; Nishide, H. J. Chem. Soc., Dalton Trans. 1993, 2465-2469.
29. Traylor, T. G.; Tsuchiya, S.; Campbell, D.; Mitchel, M.; Stynes, D.; Koga, N. J. Am. Chem. Soc. 1985, 107, 604-614.
30. The pictures were produced on the basis of crystal structure coordinatex of rHSA(wt)-hemin (1O9X, ref 9) by use of PyMOL: DeLano, W. L. The PyMOL Molecular Graphics System; DeLano Scientific: San Carlos, CA, 2002.
31. Chu, M. M. L.; Castro, C. E.; Hathaway, G. M. Biochemistry 1978, 17, 481-486.
32. Tsuchida, E.; Nishide, H.; Sato, Y.; Kaneda, M. Bull. Chem. Soc. Jpn. 1982, 55, 1890-1895.
33. Uno, T.; Sakamoto, R.; Tomisugi, Y.; Ishikawa, Y.; Wilkinson, A. Biochemistry 2003, 42, 10191-10199.
34. Vickery, L.; Nozawa, T.; Sauer, K. J. Am. Chem. Soc. 1976, 98, 343-350.
35. Collman, J. P.; Basolo, F.; Bunnenberg, E.; Collins, T. J.; Dawson, J. H.; Ellis, P. E., Jr.; Marrocco, M. L.; Moscowitz, A.; Sessler, J. L.; Szymanski, T. J. Am. Chem. Soc. 1981, 103, 5636-5648.
36. Traylor, T. G.; Chang, C. K.; Geibel, J.; Berzinis, A.; Mincey, T.; Cannon, J. J. Am. Chem. Soc. 1979, 101, 6716-6731.
37. Antonini, E.; Brunori, M. Hemoglobin and Myoglobin in Their Reactions with Ligands; North-Holland: Amsterdam, 1971; p 18.
38. Brantley, R. E., Jr.; Smerdon, S. J.; Wilkinson, A. J.; Singleton, E. W.; Olson, J. S. J. Biol. Chem. 1993, 268, 6995-7010.
39. Sharma, V. S.; Schmidt, M. R.; Ranney, H. M. J. Biol. Chem. 1976, 251, 4267-4272.
40. Gibson, Q. H. J. Biol. Chem. 1970, 245, 3285-3288.
41. Olson, J. S.; Andersen, M. E.; Gibson, Q. H. J. Biol. Chem. 1971, 246, 5919-5923.
42. Imai, K.; Morimoto, H.; Kotani, M.; Watari, H.; Hirata, W.; Kuroda, M. Biochim. Biphys. Acta. 1970, 200, 189-197.
43. Steinmeier, R. C.; Parkhurst, L. J. Biochemistry 1975, 14, 1564-1571.
44. Vickery, L.; Salmon, A.; Sauer, K. Biochim. Biophys. Acta. 1975, 386, 87-98.
45. (a) Burstyn, J. N.; Yu, A. E.; Dierks, E. A.; Hawkins, B. K.; Dawson, J. H. Biochemistry 1995, 34, 5896-5903.
46. (b) Svastits, E. W.; Dawson, J. H. Inorg. Chim. Acta. 1986, 123, 83-86.
47. Chang, C. K.; Ward, B.; Young, R.; Kondylis, M. P. J. Macromol. Sci., Chem. 1988, A25, 1307-1326.
48. Squires, J. E. Science 2002, 295, 1002-1005.
49. Tsuchida, E.; Komatsu, T.; Matsukawa, Y.; Nakagawa, A.; Sakai, H.; Kobayashi, K.; Suematsu, M. J. Biomed. Mater. Res. 2003, 64A, 257-261.