Blocking of the TLR5 activation domain hampers protective potential of flagellin DNA vaccine

Journal of Immunology

Volumn 179, Issue 2, 2007, Pages 1147-1154

  Saha, Sukumar ^a   Takeshita, Fumihiko ^a   Matsuda, Tomoko ^a   Jounai, Nao ^a   Kobiyama, Kouji ^a   Matsumoto, Tetsuya ^b   Sasaki, Shin ^a   Yoshida, Atsushi ^a   Xin, Ke Qin ^a   Klinman, Dennis M ^c   Uematsu, Satoshi ^d   Ishii, Ken J ^d,e   Akira, Shizuo ^d   Okuda, Kenji ^a  

^a YOKOHAMA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Tokyo Medical University School of Medicine   (Japan)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^d OSAKA UNIVERSITY   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; FLAGELLIN; TOLL LIKE RECEPTOR 5; VIRUS ANTIBODY; VIRUS ANTIGEN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CROSS REACTION; FEMALE; IMMUNOGENICITY; INNATE IMMUNITY; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; VACCINATION; AMINO ACID SEQUENCE; ANIMAL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; GRAM NEGATIVE INFECTION; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MUTATION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; BLOTTING, WESTERN; CROSS REACTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLAGELLIN; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; TOLL-LIKE RECEPTOR 5; VACCINES, DNA;

EID: 34548716509     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.179.2.1147     Document Type: Article

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