A comparative study of topical natural ergot alkaloids on the intraocular pressure and aqueous humor dynamics in oclular normotensive and α-chymotrypsin-induced ocular hypertensive rabbits

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 245, Issue 10, 2007, Pages 1559-1567

  Puras, Gustavo ^a   Santafé, Juan ^b   Segarra, José ^b   Garrido, Manuel ^b   Melena, José ^b  

^a UNIVERSIDAD AUTÓNOMA DE TAMAULIPAS   (Mexico)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Aqueous humor dynamic; Ergot alkaloids; Intraocular pressure; Rabbits

Indexed keywords

CHYMOTRYPSIN A; ERGOCORNINE; ERGOCRISTINE; ERGOCRYPTINE; ERGOT ALKALOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; AQUEOUS HUMOR FLOW; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

EID: 34548711805     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-007-0596-3     Document Type: Article

References (45)

1. Al-Sereiti MR, Quik RF, Turner P (1989) The effect of a single oral dose of pergolide on intraocular pressure and pupil diameter. Br J Clin Pharmacol 28:263-268
2. Barnett N, Osborne NN (1993) The presence of serotonin (5-HT1) receptors negatively coupled to adenylate cyclase in rabbit and human iris-ciliary processes. Exp Eye Res 57:209-216
3. Becker B, Constant MA (1956) The facility of aqueous outflow. A comparison of tonography and perfusion measurements in vitro and in vivo. Arch Ophthalmol 55:305-312
4. Bronner A, Hommura S (1973) Influence de l'hydergine sur l'hydrodynamique de l'humeur aqueuse et sur la circulátion rétinienne. Med Strasbourg J 4:809-816
5. Coppi G (1992) Dihydroergocristine: A review of pharmacology and toxicology. Arzneimittelforschung 42:1381-1390
6. Chang FW, Burke JA, Potter DE (1985) Mechanism of the ocular hypotensive action of ketanserin. J Ocul Pharmacol 1:137-147
7. Chidlow G, Cupido A, Melena J, Osborne NN (2001) Flesinoxan, a 5-HT1A receptor agonist/alpha 1-adrenoceptor antagonist, lowers intraocular pressure in NZW rabbits. Curr Eye Res 23:144-153
8. Chidlow G, Le Corre S, Osborne, NN (1998) Localization of 5-hydroxytryptamine1A and 5-hydroxytryptamine7 receptors in rabbit ocular and brain tissues. Neuroscience 87:675-689
9. Chu E, Socci R, Chu TC (2004) PD128,907 induces ocular hypotension in rabbits: Involvement of D2/D3 dopamine receptors and brain natriuretic peptide. J Ocul Pharmacol Ther 20:15-23
10. Chu T, Ogidigben, MJ, Potter, DE (1999) 8-OH-DPAT-induced ocular hypotension: Sites and mechanisms of action. Exp Eye Res 6:227-238
11. Diotavelli M, Auricchio G (1964) The effect of topically used hydergine on ocular tension. Ophthalmologica 147:448-454
12. Eisenlohr JE, Langham RF (1962) The relationship between pressure and volume changes in living and dead rabbit eyes. Invest Ophthalmol 1:63-67
13. Elibol O, Guler C, Yuksel N (1992) The effects of dopamine, haloperidol and bromocriptine on intraocular pressure. Int Ophthalmol 16:343-347
14. Farahbakhsh NA, Cillufo MC (1994) Synergistic effect of adrenergic and muscarinic receptor activation of [Ca2+] spikes and Ca2+ currents in rabbit ciliary body epithelial cells. Exp Eye Res 58:197-206
15. Fourman S, Fourman MB (1989) Correlation of tonography and constant pressure perfusion measurements of outflow facility in the rabbit. Curr Eye Res 9:963-969
16. Genée E, Geisendörfer T (1975) Blutdruckändernde Medikamente und Augeninnendruck im Tierversuch. Albrecht v Graefes Klin Exp Ophthal 95:187-194
17. Green K (1992) Models and methods for testing toxicity of aqueous humor, iris and ciliary body. In: Hockwin O, Green K, Rubin L (eds) Manual of oculotoxicity testing of drugs. Gustav Fischer, Stuttgart, pp 219-242
18. Hochgesand DH, Dunn JJ, Crook RB (2001) Catecholaminergic regulation of Na-K-Cl cotransport in pigmented ciliary epithelium: Differences between PE and NPE. Exp Eye Res 72:1-12
19. Krootila K, Palkama A, Uusitalo H (1987) Effect of serotonin and its antagonist (ketanserin) on intraocular pressure in the rabbit. Ocul Pharmacol J 4:279-290
20. 1-like receptor sites in the ciliary body of the rabbit eye by light microscope autoradiography. Naunyn Schmiedebergs Arch Pharmacol 346:644-648
21. Melena J, Santafé J, Segarra-Doménech J, Puras G (1999) Aqueous humor dynamics in alfa chymotrypsin-induced ocular hypertensive rabbits. J Ocul Pharmacol Ther 15:19-26
22. Melena J, Santafé J, Segarra-Doménech J (1998) The effect of topical dihydroergocristine on the intraocular pressure in chymotrypsin-induced ocular hypertensive rabbits. Meth Find Exp Clin Pharmacol 20:861-867
23. Mito T, Delamere NA, Coca-Prados M (1993) Calcium-dependent regulation of cation transport in cultured human nonpigmented ciliary epithelial cells. Am J Physiol 33:519-525
24. Neufeld AH, Page ED (1977) In vitro determination of the ability of drugs to bind to adrenergic receptors. Invest Ophthalmol Vis Sci 16:1118-1124
25. Ohuchi T, Yoshimura N, Tanihara H, Kuriyama S, Ito S, Honda Y (1992) Ca2+ mobilization in nontransformed ciliary nonpigmented epithelial cells. Invest Ophtalmol Vis Sci 33:1696-1705
26. Osborne NN, Wood JP, Melena J, Chao HM, Nash MS, Bron AJ, Chidlow G (2000) 5-Hydroxytryptamine1A agonists: Potential use in glaucoma. Evidence from animal studies. Eye 14:454-463
27. Peroutka SJ (1996) Drugs effective in the therapy of migraine. In: Hambard JG, Limbird LE (eds) Goodman & Gilman's the pharmacological basis of therapeutics, 9th edn. McGraw Hill, New York, pp 487-502
28. Potter DE (1981) Adrenergic pharmacology of aqueous humor dynamics. Pharmacol Rev 33:133-153
29. Potter DE, Ogidigben MJ, Chu TC (1998) Lisuride acts at multiple sites to induce ocular hypotension and mydriasis. Pharmacology 57:249-260
30. Potter DE, Shumate DJ (1987) Cianergoline lowers intraocular pressure in rabbits and monkeys and inhibits contraction of the cat nictitans by suppressing sympathetic neuronal function. J Ocul Pharmacol 3:309-321
31. Potter DE, Burke JA (1982) Effects of ergoline derivatives on intraocular pressure and iris function in rabbits an monkeys. Curr Eye Res 2:281-288
32. Prunte C, Nuttli I, Markstein R, Kohler C (1997) Effects of dopamine D-1 and D-2 receptors on intraocular pressure in conscious rabbits. J Neural Transm 104:111-123
33. Puras G, Santafé J, Segarra, J, Melena J (2002) Effects of topical natural ergot alkaloids on intraocular pressure and aqueous humor dynamics in ocular normotensive rabbits. J Ocul Pharmacol Ther 18:41-52
34. Puras G, Santafe J, Segarra J, Garrido M, Melena J (2002) The effect of topical natural ergot alkaloids on the intraocular pressure and aqueous humor dynamics in rabbits with alpha-chymotrypsin-induced ocular hypertension. Graefes Arch Clin Exp Ophthalmol 240:322-328
35. Quigley HA, Broman AT (2006) The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 90:262-267
36. Rintelen F, Smolik H (1950) Über den Einfluss des Hydergins auf den intraokularen and diastolischen Zentralarteriendruck. Ophthalmologica 120:100-103
37. Roquebert J, Demichel P (1987) Agonist/antagonist activity of ergocristine at alpha-adrenoceptors in the rat. Fundam Clin Pharmacol 1:23-33
38. Rowell PP, Larson BT (1999) Ergocryptine and other ergot alkaloids stimulate the release of [3H]dopamine from rat striatal synaptosomes. J Anim Sci 77:1800-1806
39. Rowland JM, Potter DE, Reiter RJ (1981) Circadian rhythm in intraocular pressure: A rabbit model. Curr Eye Res 1:169-173
40. Santafé J, Segarra J, Garrido M, Pablo V (1991) Effects of topical dihydroergocristine on intraocular pressure, aqueous humor dynamics and pupil diameter in conscious rabbits. A comparative study with timolol and pilocarpine. Meth Find Exp Clin Pharmacol 13:231-238
41. Savolainen J, Rautio J, Razzetti R, Jarvinen T (2003) A novel D2-dopaminergic and alpha2-adrenoceptor receptor agonist induces substantial and prolonged IOP decrease in normotensive rabbits. J Pharm Pharmacol 55:789-794
42. Siegel MJ, Lee PY, Podos SM, Mittag TW (1987) Effect of topical ergolide on aqueous dynamics in normal and glaucomatous monkeys. Exp Eye Res 44:227-233
43. Simkova M, Zahn K (1952) The effect of hydergine on retinal circulation. Ophthalmologica 124:39-49
44. Steinbach PD, Bell H (1977) Wirkung gefäserweiternder Substanzen auf Augeninnendruck und Blutdruck. Albrecht v Graefes Arch Klin Exp Ophthal 202:213-222
45. Sugrue MF (1997) New approaches to antiglaucoma therapy. J Med Chem 40(18):2793-2809