Mass spectrometry in medicine - The role of molecular analyses;Massenspektrometrie in der medizin - Stellenwert der molekularen analytik

Deutsches Arzteblatt

Volumn 104, Issue 31-32, 2007, Pages

  Vogeser, Michael ^a   Kobold, Uwe ^b   Seidel, Dietrich ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b ROCHE DIAGNOSTICS GMBH   (Germany)

Author keywords

Gas chromatography mass spectrometry (GC MS); Liquid chromatography tandem mass spectrometry (LC MS MS); Mass spectrometry; Metabolome; Proteome

Indexed keywords

ANDROGEN; CANNABINOID; CARNITINE ACETYLTRANSFERASE; HYDROCORTISONE; RAPAMYCIN;

CHEMICAL STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ENVIRONMENTAL HEALTH; IMMUNOASSAY; IN VITRO STUDY; IONIZATION; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEDICAL RESEARCH; MEDICINE; MOLECULAR MECHANICS; NUTRITION; REVIEW; TANDEM MASS SPECTROMETRY;

EID: 34548691491     PISSN: 00121207     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (19)

1. Dettmer K, Aronov PA, Hammock BD: Mass spectrometry-based metabolomics. Mass Spectrom Rev 2006; 26: 51-78.
2. Sabatine MS, Liu E, Morrow DA, Heller E, McCarroll R, Wiegand R, Berriz GF, Roth FP, Gerszten RE: Metabolomic identification of novel biomarkers of myocardial ischemia. Circulation 2005; 112: 3868-75.
3. Chu CY, Xiao X, Zhou XG, Lau TK, Rogers MS, Fok TF, Law LK, Pang CP, Wang CC: Metabolomic and bioinformatic analyses in asphyxiated neonates. Clin Biochem 2006; 39: 203-9.
4. Korfmacher WA: Principles and applications of LC-MS in new drug discovery. Drug Discov Today 2005; 10: 1357-67.
5. Ma S, Chowdhury SK, Alton KB: Application of mass spectrometry for metabolite identification. Curr Drug Metab 2006; 7: 503-23.
6. Ackermann BL, Hale JE, Duffin KL: The role of mass spectrometry in biomarker discovery and measurement. Curr Drug Metab 2006; 7: 525-39.
7. Vogeser M: Liquid-chromatography tandem mass-spectrometry - application in the clinical laboratory. Clin Chem Lab Med 2003; 41: 117-26.
8. Minutti CZ, Lacey JM, Magera MJ, Hahn SH, McCann M, Schulze A, Cheillan D, Dorche C, Chace DH, Lymp JF, Zimmerman D, Rinaldo P, Matern D: Steroid profiling by tandem mass spectrometry improves the positive predictive value of newborn screening for congenital adrenal hyperplasia. J Clin Endocrinol Metab 2004; 89: 3687-93.
9. Cawood ML, Field HP, Ford CG, Gillingwater S, Kicman A, Cowan D, Barth JH: Testosterone measurement by isotopedilution liquid chromatography-tandem mass spectrometry: validation of a method for routine clinical practice. Clin Chem 2005; 51: 1472-9.
10. Guo T, Taylor RL, Singh RJ, Soldin SJ: Simultaneous determination of 12 steroids by isotope dilution liquid cbramatography-photospray ionization tandem mass spectrometry. Clin Chim Acta 2006; 372: 76-82.
11. Martens-Lobenhoffer J, Krug O, Bode-Boger SM: Determination of arginine and asymmetric dimethylarginine (ADMA) in human plasma by liquid chromatography/mass spectrometry with the isotope dilution technique. J Mass Spectrom 2004; 39: 1287-94.
12. Hu CW, Wang CJ, Chang LW, Chao MR: Clinical-scale high-throughput analysis of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine by isotope-dilution liquid chromatography-tandem mass spectrometry with online solid-phase extraction. Clin Chem 2006; 52: 1381-8.
13. Wang C, Catlin DH, Demers LM, Starcevic B, Swerdloff RS: Measure ment of total serum testosterone in adult men: comparison of current laboratory methods versus liquid chromatography-tandem mass spectrometry. J Clin Endocrinol Metab 2004; 89: 534-43.
14. Vogeser M: Anwendung der HPLC-Tandem-Massenspektrometrie im Therapeutischen Drug Monitoring. J Lab Med 2005; 29: 278-86.
15. Wilcken B, Wiley V, Hammond J, Carpenter K: Screening newborns for inborn errors of metabolism by tandem mass spectrometry. N Engl J Med 2003; 348: 2304-12.
16. Gempel K, Bauer MF, Gerbitz KD: Mitochondriale Erkrankungen. Dtsch Arztebl 1999; 96: A3035-42.
17. Yin OQ, Lam SS, Lo CM, Chow MS: Rapid determination of five probe drugs and their metabolites in human plasma and urine by liquid chromatography/tandem mass spectrometry: application to cytochrome P450 phenotyping studies. Rapid Commun Mass Spectrom 2004; 18: 2921-33.
18. Haubitz M, Fliser D, Hatter H: Proteomanalyse - eine neue Perspektive für die klinische Diagnostik. Dtsch Arztebl 2004; 21: A1514-7.
19. Blievernicht JK, Schaeffeler E, Klein K, Eichelbaum M, Schwab M, Zanger UM: MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms. Clin Chem 2007; 53: 24-33.