Acute alcohol intoxication suppresses the pulmonary ELR-negative CXC chemokine response to lipopolysaccharide

Alcohol

Volumn 41, Issue 5, 2007, Pages 325-333

  Happel, Kyle I ^a   Rudner, Xiaowen ^a   Quinton, Lee J ^b   Movassaghi, Jennifer L ^a   Clark, Charles ^a   Odden, Anthony R ^a   Zhang, Ping ^a   Bagby, Gregory J ^a,c   Nelson, Steve ^a   Shellito, Judd E ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcohol abuse; I TAC; IP 10; Lipopolysaccharide; Lung; MIG

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALCOHOL; ALPHA CHEMOKINE; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; MESSENGER RNA; MIG PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATE BUFFERED SALINE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; UO 126;

ALCOHOL INTOXICATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; ENZYME PHOSPHORYLATION; GENE EXPRESSION; LUNG ALVEOLUS CELL; LUNG ALVEOLUS MACROPHAGE; MALE; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TRANSCRIPTION INITIATION;

ALCOHOLIC INTOXICATION; AMINO ACID MOTIFS; ANIMALS; CELL LINE; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CHEMOKINES, CXC; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI INFECTIONS; ETHANOL; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RNA, MESSENGER; STAT1 TRANSCRIPTION FACTOR; T-LYMPHOCYTES; TIME FACTORS;

BACTERIA (MICROORGANISMS); MUS;

EID: 34548691430     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.alcohol.2007.06.002     Document Type: Article

References (44)

1. Afessa B., and Green B. Bacterial pneumonia in hospitalized patients with HIV infection: the Pulmonary Complications, ICU Support, and Prognostic Factors of Hospitalized Patients with HIV (PIP) Study. Chest 117 4 (2000) 1017-1022
2. Astry C.L., Warr G.A., and Jakab G.J. Impairment of polymorphonuclear leukocyte immigration as a mechanism of alcohol-induced suppression of pulmonary antibacterial defenses. Am. Rev. Respir. Dis. 128 1 (1983) 113-117
3. Boe D.M., Nelson S., Zhang P., and Bagby G.J. Acute ethanol intoxication suppresses lung chemokine production following infection with Streptococcus pneumoniae. J. Infect. Dis. 184 9 (2001) 1134-1142
4. Cole K.E., Strick C.A., Paradis T.J., Ogborne K.T., Loetscher M., Gladue R.P., Lin W., Boyd J.G., Moser B., Wood D.E., et al. Interferon-inducible T cell alpha chemoattractant (I-TAC): a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3. J. Exp. Med. 187 12 (1998) 2009-2021
5. Darnell Jr. J.E., Kerr I.M., and Stark G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264 5164 (1994) 1415-1421
6. Deng J.C., Tateda K., Zeng X., and Standiford T.J. Transient transgenic expression of gamma interferon promotes Legionella pneumophila clearance in immunocompetent hosts. Infect. Immun. 69 10 (2001) 6382-6390
7. Dong C., Davis R.J., and Flavell R.A. MAP kinases in the immune response. Annu. Rev. Immunol. 20 (2002) 55-72
8. Drechsler Y., Dolganiuc A., Norkina O., Romics L., Li W., Kodys K., Bach F.H., Mandrekar P., and Szabo G. Heme oxygenase-1 mediates the anti-inflammatory effects of acute alcohol on IL-10 induction involving p38 MAPK activation in monocytes. J. Immunol. 177 4 (2006) 2592-2600
9. Farber J.M. A macrophage mRNA selectively induced by gamma-interferon encodes a member of the platelet factor 4 family of cytokines. Proc. Natl. Acad. Sci. USA 87 14 (1990) 5238-5242
10. Goral J., Choudhry M.A., and Kovacs E.J. Acute ethanol exposure inhibits macrophage IL-6 production: role of p38 and ERK1/2 MAPK. J. Leukoc. Biol. 75 3 (2004) 553-559
11. Greenberg S.S., Xie J., Ouyang J., and Zhao X. Ethanol metabolism is not required for inhibition of LPS-stimulated transcription of inducible nitric oxide synthase. Alcohol 17 3 (1999) 203-213
12. Guha M., and Mackman N. LPS induction of gene expression in human monocytes. Cell. Signal. 13 2 (2001) 85-94
13. Hambleton J., Weinstein S.L., Lem L., and DeFranco A.L. Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages. Proc. Natl. Acad. Sci. USA 93 7 (1996) 2774-2778
14. Happel K.I., and Nelson S. Alcohol, immunosuppression, and the lung. Proc. Am. Thorac. Soc. 2 5 (2005) 428-432
15. Happel K.I., Odden A.R., Zhang P., Shellito J.E., Bagby G.J., and Nelson S. Acute alcohol intoxication suppresses the interleukin 23 response to Klebsiella pneumoniae infection. Alcohol. Clin. Exp. Res. 30 7 (2006) 1200-1207
16. Hirschtick R.E., Glassroth J., Jordan M.C., Wilcosky T.C., Wallace J.M., Kvale P.A., Markowitz N., Rosen M.J., Mangura B.T., and Hopewell P.C. Bacterial pneumonia in persons infected with the human immunodeficiency virus. Pulmonary Complications of HIV Infection Study Group. N. Engl. J. Med. 333 13 (1995) 845-851
17. Kato H., Negoro M., and Wakabayashi I. Effects of acute ethanol administration on LPS-induced expression of cyclooxygenase-2 and inducible nitric oxide synthase in rat alveolar macrophages. Alcohol. Clin. Exp. Res. 29 12 Suppl (2005) 285S-293S
18. Lu H.T., Yang D.D., Wysk M., Gatti E., Mellman I., Davis R.J., and Flavell R.A. Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice. EMBO J. 18 7 (1999) 1845-1857
19. Luster A.D., and Ravetch J.V. Biochemical characterization of a gamma interferon-inducible cytokine (IP-10). J. Exp. Med. 166 4 (1987) 1084-1097
20. MacGregor R.R., Spagnuolo P.J., and Lentnek A.L. Inhibition of granulocyte adherence by ethanol, prednisone, and aspirin, measured with an assay system. N. Engl. J. Med. 291 13 (1974) 642-646
21. Mandrekar P., Catalano D., and Szabo G. Inhibition of lipopolysaccharide-mediated NFkappaB activation by ethanol in human monocytes. Int. Immunol. 11 11 (1999) 1781-1790
22. Mandrekar P., Catalano D., White B., and Szabo G. Moderate alcohol intake in humans attenuates monocyte inflammatory responses: inhibition of nuclear regulatory factor kappa B and induction of interleukin 10. Alcohol. Clin. Exp. Res. 30 1 (2006) 135-139
23. Martin-Fontecha A., Thomsen L.L., Brett S., Gerard C., Lipp M., Lanzavecchia A., and Sallusto F. Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming. Nat. Immunol. 5 12 (2004) 1260-1265
24. Medzhitov R. Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1 2 (2001) 135-145
25. Mizgerd J.P. Molecular mechanisms of neutrophil recruitment elicited by bacteria in the lungs. Semin. Immunol. 14 2 (2002) 123-132
26. Moore T.A., Moore B.B., Newstead M.W., and Standiford T.J. Gamma delta-T cells are critical for survival and early proinflammatory cytokine gene expression during murine Klebsiella pneumonia. J. Immunol. 165 5 (2000) 2643-2650
27. Morris P.E., Glass J., Cross R., and Cohen D.A. Role of T-lymphocytes in the resolution of endotoxin-induced lung injury. Inflammation 21 3 (1997) 269-278
28. Oak S., Mandrekar P., Catalano D., Kodys K., and Szabo G. J. Immunol. 176 12 (2006) 7628-7635
29. Pruett S.B., Schwab C., Zheng Q., and Fan R. Suppression of innate immunity by acute ethanol administration: a global perspective and a new mechanism beginning with inhibition of signaling through TLR3. J. Immunol. 173 4 (2004) 2715-2724
30. Pruett S.B., Zheng Q., Fan R., Matthews K., and Schwab C. Ethanol suppresses cytokine responses induced through Toll-like receptors as well as innate resistance to Escherichia coli in a mouse model for binge drinking. Alcohol 33 2 (2004) 147-155
31. Rush B. An inquiry into the effects of ardent spirits upon the human body and mind. Q. J. Stud. Alcohol 4 (1943) 321-341
32. Saitz R., Ghali W.A., and Moskowitz M.A. The impact of alcohol-related diagnoses on pneumonia outcomes. Arch. Intern. Med. 157 13 (1997) 1446-1452
33. Schmidt W., and De Lint J. Causes of death of alcoholics. Q. J. Stud. Alcohol 33 1 (1972) 171-185
34. Soto H., Wang W., Strieter R.M., Copeland N.G., Gilbert D.J., Jenkins N.A., Hedrick J., and Zlotnik A. The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3. Proc. Natl. Acad. Sci. USA 95 14 (1998) 8205-8210
35. Szabo G., Dolganiuc A., Mandrekar P., and White B. Inhibition of antigen-presenting cell functions by alcohol: implications for hepatitis C virus infection. Alcohol 33 3 (2004) 241-249
36. Szabo G., Mandrekar P., Dolganiuc A., Catalano D., and Kodys K. Reduced alloreactive T-cell activation after alcohol intake is due to impaired monocyte accessory cell function and correlates with elevated IL-10, IL-13, and decreased IFNgamma levels. Alcohol. Clin. Exp. Res. 25 12 (2001) 1766-1772
37. Weinstein S.L., Sanghera J.S., Lemke K., DeFranco A.L., and Pelech S.L. Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages. J. Biol. Chem. 267 21 (1992) 14955-14962
38. Widney D.P., Xia Y.R., Lusis A.J., and Smith J.B. The murine chemokine CXCL11 (IFN-inducible T cell alpha chemoattractant) is an IFN-gamma- and lipopolysaccharide-inducible glucocorticoid-attenuated response gene expressed in lung and other tissues during endotoxemia. J. Immunol. 164 12 (2000) 6322-6331
39. Zhang P., Bagby G.J., Happel K.I., Summer W.R., and Nelson S. Pulmonary host defenses and alcohol. Front. Biosci. 7 (2002) d1314-d1330
40. Zhang P., Bagby G.J., Stoltz D.A., Summer W.R., and Nelson S. Granulocyte colony-stimulating factor modulates the pulmonary host response to endotoxin in the absence and presence of acute ethanol intoxication. J. Infect. Dis. 179 6 (1999) 1441-1448
41. Zhang P., Bagby G.J., Xie M., Stoltz D.A., Summer W.R., and Nelson S. Acute ethanol intoxication inhibits neutrophil beta2-integrin expression in rats during endotoxemia. Alcohol. Clin. Exp. Res. 22 1 (1998) 135-141
42. Zhang P., Zhong Q., Bagby G.J., and Nelson S. Alcohol intoxication inhibits pulmonary S100A8 and S100A9 expression in rats challenged with intratracheal lipopolysaccharide. Alcohol. Clin. Exp. Res. 31 1 (2007) 113-121
43. Zhang Z., Bagby G.J., Stoltz D., Oliver P., Schwarzenberger P.O., and Kolls J.K. Prolonged ethanol treatment enhances lipopolysaccharide/phorbol myristate acetate-induced tumor necrosis factor-alpha production in human monocytic cells. Alcohol. Clin. Exp. Res. 25 3 (2001) 444-449
44. Zisman D.A., Strieter R.M., Kunkel S.L., Tsai W.C., Wilkowski J.M., Bucknell K.A., and Standiford T.J. Ethanol feeding impairs innate immunity and alters the expression of Th1- and Th2-phenotype cytokines in murine Klebsiella pneumonia. Alcohol. Clin. Exp. Res. 22 3 (1998) 621-627