Molecular characterization of vancomycin-resistant Enterococcus faecium isolates from mainland China

Journal of Clinical Microbiology

Volumn 45, Issue 9, 2007, Pages 2813-2818

  Zheng, Bo ^a,b   Tomita, Haruyoshi ^a   Yong, Hong Xiao ^b   Wang, Shan ^b   Li, Yun ^b   Ike, Yasuyoshi ^a  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; CHINA; ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM; GENE INSERTION; MEAT; MULTILOCUS SEQUENCE TYPING; NONHUMAN; PLASMID; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; TRAA GENE; VANCOMYCIN RESISTANT ENTEROCOCCUS;

BACTERIAL TYPING TECHNIQUES; CHINA; CONJUGATION, GENETIC; DNA TRANSPOSABLE ELEMENTS; DNA, BACTERIAL; ENTEROCOCCUS FAECIUM; GENE TRANSFER, HORIZONTAL; GENOTYPE; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; MOLECULAR EPIDEMIOLOGY; PLASMIDS; SEQUENCE ANALYSIS, DNA; VANCOMYCIN RESISTANCE;

ENTEROCOCCUS FAECALIS; ENTEROCOCCUS FAECIUM;

EID: 34548683196     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.00457-07     Document Type: Article

References (35)

1. Arthur, M., C. Molinas, F. Depardieu, and P. Courvalin. 1993. Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J. Bacteriol. 175:117-127.
2. Cetinkaya, Y., P. Falk, and C. G. Mayhall. 2000. Vancomycin-resistant enterococci. Clin. Microbiol. Rev. 13:686-707.
3. Clewell, D. B., and G. M. Dunny. 2002. Conjugation and genetic exchange in enterococci, p. 359-367. In M. S. Gilmore, D. B. Clewell, P. Courvalin, G. M. Dunny, B. E. Murray, and L. B. Rice, (ed.), The enterococci: pathogenesis, molecular biology, and antibiotic resistance. ASM Press, Washington, DC.
4. Courvalin, P. 2006. Vancomycin resistance in Gram-positive cocci. Clin. Infect. Dis. 42:S25-S34.
5. Dunny, G. M., R. A. Craig, R. L. Carron, and D. B. Clewell. 1979. Plasmid transfer in Streptococcus faecalis: production of multiple sex pheromones by recipients. Plasmid 2:454-465.
6. Franke, A., and D. B. Clewell. 1981. Evidence for a chromosome-borne resistance transposon (Tn916) in Streptococcus faecalis that is capable of "conjugal" transfer in the absence of a conjugative plasmid. J. Bacteriol. 145:494-502.
7. Fujila, N., M. Yoshimura, T. Komori, K. Tanimoto, and Y. Ike. 1998. First report of the isolation of high-level vancomycin-resistant Enterococcus faecium from a patient in Japan. Antimicrob. Agents Chemother. 42:2150.
8. Handwerger, S., and J. Skoble. 1995. Identification of chromosomal mobile element conferring high-level vancomycin resistance in Enterococcus faecium. Antimicrob. Agents Chemother. 39:2446-2453.
9. Hashimoto, Y., K. Tanimoto, Y. Ozawa, T. Murata, and Y. Ike. 2000. Amino acid substitutions in the VanS sensor of the VanA-type vancomycin-resistant enterococcus strains result in high-level vancomycin resistance and low-level teicoplanin resistance. FEMS Microbiol. Lett. 185:247-254.
10. Homan, W. L., T. David, S. Poznanski, M. Li, G. Hogg, E. Spalburg, J. D. A. Van Embden, and R. J. L. Willems. 2002. Multilocus sequence typing scheme for Enterococcus faecium. J. Clin. Microbiol. 40:1963-1971.
11. Huh, J. Y., W. G. Lee, K. Lee, W. S. Shin, and J. H. Yoo. 2004. Distribution of insertion sequences with Tn1546-like elements among Enterococcus faecium isolates from patients in Korea. J. Clin. Microbiol. 42:1897-1902.
12. Ike, Y., R. A. Craig, B. A. White, Y. Yagi, and D. B. Clewell. 1983. Modification of Streptococcus faecalis sex pheromones after acquisition of plasmid DNA. Proc. Natl. Acad. Sci. USA 8:5369-5373.
13. r) (65.1 kilobases) to Enterococcus strains during broth mating. J. Bacteriol. 180:4884-4892.
14. Kak, V., and J. W. Chow. 2002. Acquired antibiotic resistance in enterococci, p. 359-367. In M. S. Gilmore, D. B. Clewell, P. Courvalin, G. M. Dunny, B. E. Murray, and L. B. Rice, (ed.), The enterococci: pathogenesis, molecular biology, and antibiotic resistance. ASM Press, Washington, DC.
15. Lauderdale, T. L., L. C. McDonald, Y. R. Shiau, P. C. Chen, H. Y. Wang, J. F. Lai, and M. Ho. 2002. Vancomycin-resistant enterococci from humans and retail chickens in Taiwan with unique VanB phenotype-vanA genotype incongruence. Antimicrob. Agents Chemother. 46:525-527.
16. Leavis, H. L., R. J. L. Willems, J. Top, E. Spalburg, E. M. Mascini, A. C. Fluit, A. Hoepelman, A. J. de Neeling, and M. J. M. Bonten. 2003. Epidemic and nonepidemic multidrug-resistant Enterococcus faecium. Emerg. Infect. Dis. 9:1108-1115.
17. Leclercq, R., E. Derlot, J. Duval, and P. Courvalin. 1988. Plasmid-mediated resistance to vancomycin and teicoplanin in Enterococcus faecium. N. Engl. J. Med. 319:157-161.
18. Ozawa, V., K. Tanimoto, T. Nomura, M. Yoshinaga, Y. Arakawam, and Y. Ike. 2002. Vancomycin-resistant enterococci in humans and imported chickens in Japan. Appl. Environ. Microbiol. 68:6457-6461.
19. Palepou, M. F. I., A. M. A. Adebiyi, C. H. Tremlett, L. B. Jensen, and N. Woodford. 1998. Molecular analysis of diverse elements mediating VanA glycopeptide resistance in enterococci. J. Antimicrob. Chemother. 42:605-612.
20. Sahm, D. F., J. Kissinger, M. S. Gilmore, P. R. Murray, R. Mulder, J. Solliday, and B. Clarke. 1989. In vitro susceptibility studies of vancomycin-resistant Enterococcus faecalis. Antimicrob. Agents Chemother. 33:1588-1591.
21. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
22. Schouten, M. A., R. J. L. Willems, W. A. G. Kraak, J. Top, J. A. A. Hoogkamp-Korstanje, and A. Voss. 2001. Molecular analysis of Tn1546-like elements in vancomycin-resistant enterococci isolated from patients in Europe shows geographic transposon type clustering. Antimicrob. Agents Chemother. 45:986-989.
23. Takeuchi, K., H. Tomita, S. Fujimoto, M. Kudo, H. Kuwano, and Y. Ike. 2005. Drug resistance of Enterococcus faecium clinical isolates and the conjugative transfer of gentamicin and erythromycin resistance traits. FEMS Microbiol. Lett. 243:347-354.
24. Tanimoto, K., and Y. Ike. 2002. Analysis of the conjugal transfer system of the pheromone-independent highly transferable Enterococcus plasmid pMG1: identification of a tra gene (traA) up-regulated during conjugation. J. Bacteriol. 184:5800-5804.
25. Tanimoto, K., T. Nomura, H. Hamatani, Y. H. Xiao, and Y. Ike. 2005. A vancomycin-dependent VanA-type Enterococcus faecalis strain isolated in Japan from chickens imported from China. Lett. Appl. Microbiol. 41:157-162.
26. Tomita, H., and Y. Ike. 2005. Genetic analysis of transfer-related regions of the vancomycin resistance Enterococcus conjugative plasmid pHTβ: identification of oriT and a putative relaxase gene. J. Bacteriol. 187:7727-7737.
27. Tomita, H., C. Pierson, S. K. Lim, D. B. Clewell, and Y. Ike. 2002. Possible connection between a widely disseminated conjugative gentamicin resistance (pMG1-like) plasmid and the emergence of vancomycin resistance in Enterococcus faecium. J. Clin. Microbiol. 40:3326-3333.
28. Tomita, H., K. Tanimoto, S. Hayakawa, K. Morinaga. K. Ezaki, H. Oshima, and Y. Ike. 2003. Highly conjugative pMG1-like plasmids carrying Tn1546-like transposons that encode vancomycin resistance in Enterococcus faecium. J. Bacteriol. 185:7024-7028.
29. Uttley, A. H., C. H. Collins, J. Naidoo, and R. C. George. 1988. Vancomycin-resistant enterococci. Lancet i:57-58.
30. Willems, R. J., W. Homan, J. Top, M. van Santen-Verheuvel, D. Tribe, X. Manzioros, C. Gaillard, C. Vandenbroucke-Grauls, E. Mascini, and E. van Kregten. 2001. Variant esp gene as a marker of a distinct genetic lineage of vancomycin-resistant spreading in hospitals. Lancet 357:853-855.
31. Willems, K. J. L., J. Top, N. van den Braak, A. van Belkum, D. J. Mevius, G. Hendriks, M. van Santen-Verheuvel, and J. D. A. van Embden. 1999. Molecular diversity and evolutionary relationships of Tn1546-like elements in enterococci from humans and animals. Antimicrob. Agents Chemother. 43:483-491.
32. Willems, R. J. L., J. Top, M. van Santen, D. A. Robinson, T. M. Coque, F. Baquero, H. Grundmann, and M. J. M. Bonten. 2005. Global spread of vancomycin-resistant Enterococcus faecium from a distinct nosocomial genetic complex. Emerg. Infect. Dis. 11:821-828.
33. Woodford, N., A. A. Adebiyi, M. I. Palepou, and B. D. Cookson. 1998. Diversity of VanA glycopeptide resistance elements in enterococci from humans and nonhuman sources. Antimicrob. Agents Chemother. 42:502-508.
34. Yu, H. S., S. Y. Seol, and D. T. Cho. 2003. Diversity of Tn1546-like elements in vancomycin-resistant enterococci isolated from humans and poultry in Korea. J. Clin. Microbiol. 41:2641-2643.
35. Zheng, B., H. Tomita, Y. H. Xiao, and Y. Ike. 2007. The first molecular analysis of clinical isolates of VanA-type vancomycin-resistant Enterococcus faecium strains in mainland China. Lett. Appl. Microbiol., in press.