Distribution of Insertion Sequences Associated with Tn1546-Like Elements among Enterococcus faecium Isolates from Patients in Korea

Journal of Clinical Microbiology

Volumn 42, Issue 5, 2004, Pages 1897-1902

  Huh, Ji Young ^a   Lee, Wee Gyo ^a,d   Lee, Kyungwon ^b   Shin, Wan Shik ^c   Yoo, Jin Hong ^c  

^a Ajou University School of Medicine   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c The Catholic University of Korea College of Medicine   (South Korea)

^d Ajou University Medical Center   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATE; CANADA; CLONAL VARIATION; ENTEROCOCCUS FAECIUM; GENE CLUSTER; GENE INSERTION SEQUENCE; GENE MAPPING; GENETIC VARIABILITY; GEOGRAPHIC DISTRIBUTION; KOREA; NONHUMAN; OPEN READING FRAME; PHYLOGENETIC TREE; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; UNITED KINGDOM; VANA GENE;

BACTERIAL PROTEINS; BASE SEQUENCE; CARBON-OXYGEN LIGASES; CHROMOSOME MAPPING; DNA PRIMERS; DNA TRANSPOSABLE ELEMENTS; DNA, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; ENTEROCOCCUS FAECIUM; GENES, BACTERIAL; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; KOREA; MULTIGENE FAMILY; VANCOMYCIN RESISTANCE;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS; ENTEROCOCCUS FAECIUM; INSERTION SEQUENCES; NEGIBACTERIA; UNIDENTIFIED INSERTION SEQUENCE;

EID: 2442455730     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.42.5.1897-1902.2004     Document Type: Article

References (23)

1. Arthur, M., C. Molinas, F. Depardieu, and P. Courvalin. 1993. Characterization of Tn1546, a Tn3-related transposon conferring glycopeptide resistance by synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147. J. Bacteriol. 175:117-127.
2. Brown, A. R., A. C. Townsley, and S. G. B. Amyes. 2001. Diversity of Tn1546 elements in clinical isolates of glycopeptide-resistant enterococci from Scottish hospitals. Antimicrob. Agents Chemother. 45:1309-1311.
3. Dahl, K. E., G. S. Simonsen, Ø. Olsvik, and A. Sundsfjord. 1999. Heterogeneity in the vanB gene cluster of genomically diverse clinical strains of vancomycin-resistant enterococci. Antimicrob. Agents Chemother. 43:1105-1110.
4. Darini, A. L. C., M. I. Palepou, and N. Woodford. 1999. Nucleotide sequence of IS1542, an insertion sequence identified within VanA glycopeptide resistance elements of enterococci. FEMS Microbiol. Lett. 173:341-346.
5. Donabedian, S., E. Hershberger, L. A. Thal, J. W. Chow, D. B. Clewell, B. Robinson-Dunn, and M. J. Zervos. 2000. PCR fragment length polymorphism analysis of vancomycin-resistant Enterococcus faecium. J. Clin. Microbiol. 38:2885-2888.
6. Dutka-Malen, S., S. Evers, and P. Courvalin. 1995. Detection of glycopeptide resistance genotypes and identification to the species level of clinically relevant enterococci by PCR. J. Clin. Microbiol. 33:24-27.
7. Handwerger, S., and J. Skoble. 1995. Identification of chromosomal mobile element conferring high-level vancomycin resistance in Enterococcus faecium. Antimicrob. Agents Chemother. 39:2446-2453.
8. Hashimoto, Y., K. Tanimoto, Y. Ozawa, T. Murata, and Y. Ike. 2000. Amino acid substitutions in the VanS sensor of the VanA-type vancomycin-resistant Enterococcus strains result in high-level vancomycin resistance and low-level teicoplanin resistance. FEMS Microbiol. Lett. 185:247-254.
9. Jensen, L. B., P. Ahrens, L. Dons, R. N. Jones, A. M. Hammerum, and F. M. Aarestrup. 1998. Molecular analysis of Tn1546 in Enterococcus faecium isolated from animals and humans. J. Clin. Microbiol. 36:437-442.
10. Kim, J. M., and Y. G. Song. 1998. Vancomycin-resistant enterococcal infections in Korea. Yonsei Med. J. 39:562-568.
11. Lee, W. G., J. A. Jernigan, J. K. Rasheed, G. J. Anderson, and F. C. Tenover. 2001. Possible horizontal transfer of the vanB2 gene among genetically diverse strains of vancomycin-resistant Enterococcus faecium in a Korean hospital. J. Clin. Microbiol. 39:1165-1168.
12. Mackinnon, M. G., M. A. Drebot, and G. J. Tyrrell. 1997. Identification and characterization of IS1476, an insertion sequence-like element that disrupts VanY function in a vancomycin-resistant Enterococcus faecium strain. Antimicrob. Agents Chemother. 41:1805-1807.
13. Perichon, B., B. Casadewall, P. Reynolds, and P. Courvalin. 2000. Glycopeptide-resistant Enterococcus faecium BM4416 is a VanD-type strain with an impaired D-alanine:D-alanine ligase. Antimicrob. Agents Chemother. 44: 1346-1348.
14. Schouten, M. A., R. J. L. Willems, W. A. G. Kraak, J. Top, J. A. A. Hoogkamp-Korstanje, and A. Voss. 2001. Molecular analysis of Tn1546-like elements in vancomycin-resistant enterococci isolated from patients in Europe shows geographic transposon type clustering. Antimicrob. Agents Chemother. 45:986-989.
15. Shin, J. W., D. Yong, M. S. Kim, K. H. Chang, K. Lee, J. M. Kim, and Y. Chong. 2003. Sudden increase of vancomycin-resistant enterococcal infections in a Korean tertiary care hospital: possible consequences of increased use of oral vancomycin. J. Infect. Chemother. 9:62-67.
16. Simonsen, G. S., H. Haaheim, K. H. Dahl, H. Kruse, A. Lovseth, Ø. Olsvik, and A. Sundsfjord. 1998. Transmission of VanA-type vancomycin-resistant enterococci and vanA resistance elements between chicken and humans at avoparcin-exposed farms. Microb. Drug Resist. 4:313-318.
17. Simonsen, G. S., M. R. M. Myhre, K. H. Dahl, O. Olsvik, and A. Sundsfjord. 2000. Typeability of Tn1546-like elements in vancomycin-resistant enterococci using long-range PCRs and specific analysis of polymorphic regions. Microb. Drug Resist. 6:49-57.
18. Stobberingh, E., A. van den Bogaard, N. London, C. Driessen, J. Top, and R. Willems. 1999. Enterococci with glycopeptide resistance in turkeys, turkey farmers, turkey slaughterers, and (sub)urban residents in the south of The Netherlands: evidence for transmission of vancomycin resistance from animals to humans? Antimicrob. Agents Chemother. 43:2215-2221.
19. van den Bogaard, A. E., R. Willems, N. London, J. Top, and E. E. Stobberingh. 2002. Antibiotic resistance of faecal enterococci in poultry, poultry farmers and poultry slaughterers. J. Antimicrob. Chemother. 49:497-505.
20. Willems, R. J. L., J. Top, N. van den Braak, A. van Belkum, D. J. Mevius, G. Hendriks, M. van Santen-Verheuvel, and J. D. A. van Embden. 1999. Molecular diversity and evolutionary relationships of Tn1546-like elements in enterococci from humans and animals. Antimicrob. Agents Chemother. 43: 483-491.
21. Woodford, N. 1998. Glycopeptide-resistant enterococci: a decade of experience. J. Med. Microbiol. 47:849-862.
22. Woodford, N., A. M. A. Adebiyi, M. I. Palepou, and B. D. Cookson. 1998. Diversity of VanA glycopeptide resistance elements in enterococci from human and nonhuman sources. Antimicrob. Agents Chemother. 42:502-508.
23. Yu, H. S., S. Y. Seol, and D. T. Cho. 2003. Diversity of Tn1546-like elements in vancomycin-resistant enterococci isolated from humans and poultry in Korea. J. Clin. Microbiol. 41:2641-2643.