Toward development of a novel NOD/SCID-based in vivo strategy to model multiple myeloma pathogenesis

Experimental Hematology

Volumn 35, Issue 10, 2007, Pages 1477-1478

  Bueno, Clara ^a   Lopes, Luiz F ^b   Greaves, Mel ^b   Menendez, Pablo ^a  

^a Instituto de Investigaciones Biomídicas   (Spain)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MARROW TRANSPLANTATION; CANCER MODEL; CELL INTERACTION; COMBINED IMMUNODEFICIENCY; CROSS REACTION; IMMUNOPATHOGENESIS; IMMUNOPHENOTYPING; IN VIVO CULTURE; LETTER; MALIGNANT TRANSFORMATION; MULTIPLE MYELOMA; NONHUMAN; NONOBESE DIABETIC MOUSE; PHASE TRANSITION; PRIORITY JOURNAL; SCID MOUSE; XENOGRAFT;

ANIMALS; ANTIBODIES, MONOCLONAL; BONE MARROW; CELL SURVIVAL; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOGLOBULIN G; MICE; MICE, INBRED NOD; MICE, SCID; MULTIPLE MYELOMA; OSTEOLYSIS; PLASMA CELLS; SIGNAL TRANSDUCTION; STROMAL CELLS;

EID: 34548676573     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2007.06.012     Document Type: Letter

References (10)

1. Mitsiades C.S., Mitsiades N., Munshi N.C., and Anderson K.C. Focus on multiple myeloma. Cancer Cell 6 (2004) 439-444
2. Barabe F., Kennedy J.A., Hope K.J., and Dick J.E. Modeling the initiation and progression of human acute leukaemia in mice. Science 316 (2007) 600-604
3. O&Brien C.A., Pollett A., Gallinger S., and Dick J.E. A human colon cancer capable of initiating tumour growth in immunodeficient mice. Nature 445 (2007) 106-110
4. Mitsiades C.S., Mitsiades N.S., Bronson R.T., et al. Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical implications. Cancer Res 63 (2003) 6689-6696
5. Yaccoby S., Barlogie B., and Epstein J. Primary myeloma cells growing in SCID-hu mice: a model for studying the biology and treatment of myeloma and its manifestations. Blood 92 (1998) 2908-2913
6. Tassone P., Neri P., Carrasco D.R., et al. A clinically relevant SCID-hu in vivo model of human multiple myeloma. Blood 106 (2005) 713-716
7. Levac K., Menendez P., and Bhatia M. Intra-bone marrow transplantation facilitates pauci-clonal human hematopoietic repopulation of NOD/SCID/b2m(-/-) mice. Exp Hematol 33 (2005) 1417-1426
8. Wang L., Menendez P., Shojaei F., et al. Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J Exp Med 201 (2005) 1603-1614
9. Mazurier F., Doedens M., and Dick J.E. Rapid myeloid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells. Nat Med 9 (2003) 959-963
10. Shultz L.D., Lyons B.L., Burzenski L.M., et al. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells. J Immunol 174 (2005) 6477-6489