High prevalence of an active human cytomegalovirus infection in patients with colonic diverticulitis

Journal of Clinical Virology

Volumn 40, Issue 2, 2007, Pages 116-119

  Hollink, N ^a   Dzabic, M ^a   Wolmer, N ^a   Bostrom L ^b   Rahbar, A ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b STOCKHOLM SÖDER HOSPITAL   (Sweden)

Author keywords

Diverticulitis; HCMV; Perforated diverticulitis

Indexed keywords

CYTOMEGALOVIRUS ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ANTIGEN DETECTION; ARTICLE; CLINICAL ARTICLE; COLON DIVERTICULOSIS; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DISEASE ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY DISEASE; PREVALENCE; PRIORITY JOURNAL; VIRUS PATHOGENESIS;

ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DISEASE PROGRESSION; DIVERTICULITIS, COLONIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMEDIATE-EARLY PROTEINS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOHISTOCHEMISTRY; MALE; PREVALENCE;

EID: 34548670475     PISSN: 13866532     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcv.2007.07.008     Document Type: Article

References (16)

1. Ahlfors K. IgG antibodies to cytomegalovirus in a normal urban Swedish population. Scand J Infect Dis 16 (1984) 335-337
2. Brian West A. The pathology of diverticulosis: classical concepts and mucosal changes in diverticula. J Clin Gastroenterol 40 (2006) S126-S131
3. Cobbs C.S., Harkins L., Samanta M., Gillespie G.Y., Bharara S., King P.H., et al. Human cytomegalovirus infection and expression in human malignant glioma. Cancer Res 62 (2002) 3347-3350
4. Corrado E., and Novo S. Role of inflammation and infection in vascular disease. Acta Chir Belg 105 (2005) 567-579
5. Doniger J., Muralidhar S., and Rosenthal L.J. Human cytomegalovirus and human herpesvirus 6 genes that transform and transactivate. Clin Microbiol Rev 12 (1999) 367-382
6. Ferzoco L.B., Raptopoulos V., and Silen W. Acute diverticulitis. N Engl J Med 338 (1998) 1521-1526
7. Floch M.H. A hypothesis: is diverticulitis a type of inflammatory bowel disease?. J Clin Gastroenterol 40 (2006) S121-S125
8. Freeman S.R., and McNally P.R. Diverticulitis. Med Clin N Am 77 (1993) 1149-1167
9. Landolfo S., Gariglio M., Gribaudo G., and Lembo D. The human cytomegalovirus. Pharmacol Ther 98 (2003) 269-297
10. Mocarski Jr. E.S. Immunomodulation by cytomegaloviruses: manipulative strategies beyond evasion. Trends Microbiol 10 (2002) 332-339
11. Peppercorn M.A. The overlap of inflammatory bowel disease and diverticular disease. J Clin Gastroenterol 38 (2004) S8-S10
12. Rahbar A., Bostrom L., Lagerstedt U., Magnusson I., Soderberg-Naucler C., and Sundqvist V.A. Evidence of active cytomegalovirus infection and increased production of IL-6 in tissue specimens obtained from patients with inflammatory bowel diseases. Inflamm Bowel Dis 9 (2003) 154-161
13. Soderberg-Naucler C. Does cytomegalovirus play a causative role in the development of various inflammatory diseases and cancer?. J Intern Med 259 (2006) 219-246
14. Soderberg-Naucler C. Human cytomegalovirus persists in its host and attacks and avoids elimination by the immune system. Crit Rev Immunol 26 (2006) 231-264
15. Soderberg-Naucler C., Fish K.N., and Nelson J.A. Interferon-gamma and tumor necrosis factor-alpha specifically induce formation of cytomegalovirus-permissive monocyte-derived macrophages that are refractory to the antiviral activity of these cytokines. J Clin Invest 100 (1997) 3154-3163
16. Soderberg-Naucler C., Fish K.N., and Nelson J.A. Reactivation of latent human cytomegalovirus by allogeneic stimulation of blood cells from healthy donors. Cell 91 (1997) 119-126