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Volumn 20, Issue 5, 2007, Pages 435-439

Nocebo hyperalgesia: How anxiety is turned into pain

Author keywords

Anxiety; Cholecystokinin; Nocebo; Placebo

Indexed keywords

BENZODIAZEPINE; CHLORDIAZEPOXIDE; CHOLECYSTOKININ; CHOLECYSTOKININ RECEPTOR BLOCKING AGENT; DIAZEPAM; MORPHINE; NALOXONE; PLACEBO; PROGLUMIDE;

EID: 34548667203     PISSN: 09527907     EISSN: None     Source Type: Journal    
DOI: 10.1097/ACO.0b013e3282b972fb     Document Type: Review
Times cited : (239)

References (53)
  • 1
    • 0021018455 scopus 로고
    • Cognitive reversal of expected nitrous oxide analgesia for acute pain
    • Dworkin SF, Chen AC, LeResche L, Clark DW. Cognitive reversal of expected nitrous oxide analgesia for acute pain. Anesth Analg 1983; 62:1073-1077.
    • (1983) Anesth Analg , vol.62 , pp. 1073-1077
    • Dworkin, S.F.1    Chen, A.C.2    LeResche, L.3    Clark, D.W.4
  • 2
    • 27744531525 scopus 로고    scopus 로고
    • Neurobiological mechanisms of the placebo effect
    • Benedetti F, Mayberg HS, Wager TD, et al. Neurobiological mechanisms of the placebo effect. J Neurosci 2005; 25:10390-10402.
    • (2005) J Neurosci , vol.25 , pp. 10390-10402
    • Benedetti, F.1    Mayberg, H.S.2    Wager, T.D.3
  • 3
    • 21744454896 scopus 로고    scopus 로고
    • Placebos and painkillers: Is mind as really as matter?
    • Colloca L, Benedetti F. Placebos and painkillers: is mind as really as matter? Nat Rev Neurosci 2005; 6:545-552.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 545-552
    • Colloca, L.1    Benedetti, F.2
  • 5
    • 33746829987 scopus 로고    scopus 로고
    • Expectations and associations that heal: Immunomodulatory placebo effects and its neurobiology
    • This article reviews how the brain modulates peripheral immune reactivity through mechanisms of behavioral conditioning in animal experiments and human studies
    • Pacheco-Lopez G, Engler H, Niemi MB, Schedlowski M. Expectations and associations that heal: immunomodulatory placebo effects and its neurobiology. Brain Behav Immun 2006; 20:430-446. This article reviews how the brain modulates peripheral immune reactivity through mechanisms of behavioral conditioning in animal experiments and human studies.
    • (2006) Brain Behav Immun , vol.20 , pp. 430-446
    • Pacheco-Lopez, G.1    Engler, H.2    Niemi, M.B.3    Schedlowski, M.4
  • 6
    • 0037704429 scopus 로고    scopus 로고
    • Conscious expectation and unconscious conditioning in analgesic, motor and hormonal placebo/nocebo responses
    • Benedetti F, Pollo A, Lopiano L, et al. Conscious expectation and unconscious conditioning in analgesic, motor and hormonal placebo/nocebo responses. J Neurosci 2003; 23:4315-4323.
    • (2003) J Neurosci , vol.23 , pp. 4315-4323
    • Benedetti, F.1    Pollo, A.2    Lopiano, L.3
  • 7
    • 14044274119 scopus 로고    scopus 로고
    • Mechanisms of the placebo response and their impact on clinical trials and clinical practice
    • Finniss DG, Benedetti F. Mechanisms of the placebo response and their impact on clinical trials and clinical practice. Pain 2005; 114:3-6.
    • (2005) Pain , vol.114 , pp. 3-6
    • Finniss, D.G.1    Benedetti, F.2
  • 8
  • 9
    • 0032938389 scopus 로고    scopus 로고
    • Neuropharmacological dissection of placebo analgesia: Expectation-activated opioid systems versus conditioning-activated specific sub-systems
    • Amanzio M, Benedetti F. Neuropharmacological dissection of placebo analgesia: expectation-activated opioid systems versus conditioning-activated specific sub-systems. J Neurosci 1999; 19:484-494.
    • (1999) J Neurosci , vol.19 , pp. 484-494
    • Amanzio, M.1    Benedetti, F.2
  • 10
    • 23944464949 scopus 로고    scopus 로고
    • Placebo effects mediated by endogenous opioid activity on m-opioid receptors
    • Zubieta JK, Bueller JA, Jackson LR, et al. Placebo effects mediated by endogenous opioid activity on m-opioid receptors. J Neurosci 2005; 25:7754-7762.
    • (2005) J Neurosci , vol.25 , pp. 7754-7762
    • Zubieta, J.K.1    Bueller, J.A.2    Jackson, L.R.3
  • 11
    • 0036500024 scopus 로고    scopus 로고
    • Placebo and opioid analgesia - imaging a shared neuronal network
    • Petrovic P, Kalso E, Petersson KM, Ingvar M. Placebo and opioid analgesia - imaging a shared neuronal network. Science 2002; 295:1737-1740.
    • (2002) Science , vol.295 , pp. 1737-1740
    • Petrovic, P.1    Kalso, E.2    Petersson, K.M.3    Ingvar, M.4
  • 12
    • 1242352025 scopus 로고    scopus 로고
    • Placebo-induced changes in fMRI in the anticipation and experience of pain
    • Wager TD, Rilling JK, Smith EE, et al. Placebo-induced changes in fMRI in the anticipation and experience of pain. Science 2004; 303:1162-1167.
    • (2004) Science , vol.303 , pp. 1162-1167
    • Wager, T.D.1    Rilling, J.K.2    Smith, E.E.3
  • 13
    • 33746380579 scopus 로고    scopus 로고
    • Price DD, Zhou Q, Moshiree B, et al. Peripheral and central contributions to hyperalgesia in irritable bowel syndrome. J Pain 2006; 7:529-535. The synergism between abnormal afferent processing and nocebo effect, which occurs in chronic abdominal pain of patients with irritable bowel syndrome, is discussed.
    • Price DD, Zhou Q, Moshiree B, et al. Peripheral and central contributions to hyperalgesia in irritable bowel syndrome. J Pain 2006; 7:529-535. The synergism between abnormal afferent processing and nocebo effect, which occurs in chronic abdominal pain of patients with irritable bowel syndrome, is discussed.
  • 14
    • 0035838997 scopus 로고    scopus 로고
    • Expectation and dopamine release: Mechanism of the placebo effect in Parkinson's disease
    • De la Fuente-Fernandez R, Ruth TJ, Sossi V, et al. Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease. Science 2001; 293:1164-1166.
    • (2001) Science , vol.293 , pp. 1164-1166
    • De la Fuente-Fernandez, R.1    Ruth, T.J.2    Sossi, V.3
  • 15
    • 2542462054 scopus 로고    scopus 로고
    • Placebo-responsive Parkinson patients show decreased activity in single neurons of subthalamic nucleus
    • Benedetti F, Colloca L, Torre E, et al. Placebo-responsive Parkinson patients show decreased activity in single neurons of subthalamic nucleus. Nat Neurosci 2004; 7:587-588.
    • (2004) Nat Neurosci , vol.7 , pp. 587-588
    • Benedetti, F.1    Colloca, L.2    Torre, E.3
  • 16
    • 21744448120 scopus 로고    scopus 로고
    • Placebo-induced analgesia: Methodology, neurobiology, clinical use, and ethics
    • Benedetti F, Colloca L. Placebo-induced analgesia: methodology, neurobiology, clinical use, and ethics. Rev Analg 2004; 7:129-143.
    • (2004) Rev Analg , vol.7 , pp. 129-143
    • Benedetti, F.1    Colloca, L.2
  • 17
    • 5644272620 scopus 로고    scopus 로고
    • Overt versus covert treatment for pain, anxiety, and Parkinson's disease
    • Colloca L, Lopiano L, Lanotte M, Benedetti F. Overt versus covert treatment for pain, anxiety, and Parkinson's disease. Lancet Neurol 2004; 3:679-684.
    • (2004) Lancet Neurol , vol.3 , pp. 679-684
    • Colloca, L.1    Lopiano, L.2    Lanotte, M.3    Benedetti, F.4
  • 18
    • 72949149379 scopus 로고
    • The nocebo reaction
    • Kennedy WP. The nocebo reaction. Med World 1961; 95:203-205.
    • (1961) Med World , vol.95 , pp. 203-205
    • Kennedy, W.P.1
  • 20
    • 0010429293 scopus 로고
    • A sociocultural model of illness and healing
    • White L, Tursky B, Schwartz GE, editors, New York: Guilford;
    • Hahn RA. A sociocultural model of illness and healing. In: White L, Tursky B, Schwartz GE, editors. Placebo: theory, research, and mechanisms. New York: Guilford; 1985. pp. 332-350.
    • (1985) Placebo: Theory, research, and mechanisms , pp. 332-350
    • Hahn, R.A.1
  • 21
    • 0030885457 scopus 로고    scopus 로고
    • Hahn RA. The nocebo phenomenon: concept, evidence, and implications for public health. Prev Med 1997; 26 (5Pt1):607-611.
    • Hahn RA. The nocebo phenomenon: concept, evidence, and implications for public health. Prev Med 1997; 26 (5Pt1):607-611.
  • 22
    • 34250204872 scopus 로고    scopus 로고
    • When words are painful: Unraveling the mechanisms of the nocebo effect
    • A thorough review to present how nocebo and nocebo-related effects may affect the course of a disease and the response to a therapy
    • Benedetti F, Lanotte M, Lopiano L, Colloca L. When words are painful: unraveling the mechanisms of the nocebo effect. Neuroscience 2007; 147:260-271. A thorough review to present how nocebo and nocebo-related effects may affect the course of a disease and the response to a therapy.
    • (2007) Neuroscience , vol.147 , pp. 260-271
    • Benedetti, F.1    Lanotte, M.2    Lopiano, L.3    Colloca, L.4
  • 23
    • 0032951114 scopus 로고    scopus 로고
    • Drug-related information generates placebo and nocebo responses that modify the drug response
    • Flaten MA, Simonsen T, Olsen H. Drug-related information generates placebo and nocebo responses that modify the drug response. Psychosom Med 1999; 61:250-255.
    • (1999) Psychosom Med , vol.61 , pp. 250-255
    • Flaten, M.A.1    Simonsen, T.2    Olsen, H.3
  • 24
    • 0037028769 scopus 로고    scopus 로고
    • Nonspecific medication side effects and the nocebo phenomenon
    • Barsky AJ, Saintfort R, Rogers MP, Borus JF. Nonspecific medication side effects and the nocebo phenomenon. JAMA 2002; 287:622-627.
    • (2002) JAMA , vol.287 , pp. 622-627
    • Barsky, A.J.1    Saintfort, R.2    Rogers, M.P.3    Borus, J.F.4
  • 25
    • 34247378723 scopus 로고    scopus 로고
    • Mobile phone headache: A double blind, sham-controlled provocation study
    • This double-blind, sham-controlled provocation study provides evidence that subjective symptoms such as head pain or discomfort are nocebo effects and not symptoms related to exposure to radiofrequency fields from mobile phones
    • Oftedal G, Straume A, Johnsson A, Stovner LJ. Mobile phone headache: a double blind, sham-controlled provocation study. Cephalalgia 2007; 27:447-455. This double-blind, sham-controlled provocation study provides evidence that subjective symptoms such as head pain or discomfort are nocebo effects and not symptoms related to exposure to radiofrequency fields from mobile phones.
    • (2007) Cephalalgia , vol.27 , pp. 447-455
    • Oftedal, G.1    Straume, A.2    Johnsson, A.3    Stovner, L.J.4
  • 26
    • 33845599980 scopus 로고    scopus 로고
    • Price DD, Craggs J, Nicholas Verne G, et al. Placebo analgesia is accompanied by large reductions in pain-related brain activity in irritable bowel syndrome patients. Pain 2007; 127:63-72. This study is important because demonstrates the neural correlates of the placebo analgesic effect in clinically relevant conditions.
    • Price DD, Craggs J, Nicholas Verne G, et al. Placebo analgesia is accompanied by large reductions in pain-related brain activity in irritable bowel syndrome patients. Pain 2007; 127:63-72. This study is important because demonstrates the neural correlates of the placebo analgesic effect in clinically relevant conditions.
  • 27
    • 27944431780 scopus 로고    scopus 로고
    • The role of placebo and nocebo effects of perioperative administration of sedatives and opioids in interventional pain management
    • Manchikanti L, Pampati V, Damron K. The role of placebo and nocebo effects of perioperative administration of sedatives and opioids in interventional pain management. Pain Physician 2005; 8:349-355.
    • (2005) Pain Physician , vol.8 , pp. 349-355
    • Manchikanti, L.1    Pampati, V.2    Damron, K.3
  • 28
  • 29
    • 0034177466 scopus 로고    scopus 로고
    • Fear-avoidance and its consequences in chronic musculoskeletal pain: A state of the art
    • Vlaeyen JW, Linton SJ. Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. Pain 2000; 85:317-332.
    • (2000) Pain , vol.85 , pp. 317-332
    • Vlaeyen, J.W.1    Linton, S.J.2
  • 30
    • 33846818708 scopus 로고    scopus 로고
    • Leeuw M, Goossens ME, Linton SJ, et al. The fear-avoidance model of musculoskeletal pain: current state of scientific evidence. J Behav Med 2007; 30:77-94. This review presents the state of the art of the role of fear in pain severity, pain catastrophizing, attention to pain, escape/avoidance behavior, disability, disuse and vulnerability.
    • Leeuw M, Goossens ME, Linton SJ, et al. The fear-avoidance model of musculoskeletal pain: current state of scientific evidence. J Behav Med 2007; 30:77-94. This review presents the state of the art of the role of fear in pain severity, pain catastrophizing, attention to pain, escape/avoidance behavior, disability, disuse and vulnerability.
  • 31
    • 0031005356 scopus 로고    scopus 로고
    • The neurobiology of placebo analgesia: From endogenous opioids to cholecystokinin
    • Benedetti F, Amanzio M. The neurobiology of placebo analgesia: from endogenous opioids to cholecystokinin. Prog Neurobiol 1997; 52:109-125.
    • (1997) Prog Neurobiol , vol.52 , pp. 109-125
    • Benedetti, F.1    Amanzio, M.2
  • 32
    • 0032708056 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors
    • Noble F, Wank SA, Crawley JN, et al. International Union of Pharmacology. XXI. Structure, distribution, and functions of cholecystokinin receptors. Pharmacol Rev 1999; 51:745-781.
    • (1999) Pharmacol Rev , vol.51 , pp. 745-781
    • Noble, F.1    Wank, S.A.2    Crawley, J.N.3
  • 33
    • 0030958301 scopus 로고    scopus 로고
    • Blockade of nocebo hyperalgesia by the cholecystokinin antagonist proglumide
    • Benedetti F, Amanzio M, Casadio C, et al. Blockade of nocebo hyperalgesia by the cholecystokinin antagonist proglumide. Pain 1997; 71:135-140.
    • (1997) Pain , vol.71 , pp. 135-140
    • Benedetti, F.1    Amanzio, M.2    Casadio, C.3
  • 34
    • 33751085385 scopus 로고    scopus 로고
    • The biochemical and neuroendocrine bases of the hyperalgesic nocebo effect
    • This neuropharmacological study provides evidence for a CCKergic link between anxiety and hyperalgesia in humans
    • Benedetti F, Amanzio M, Vighetti S, Asteggiano G. The biochemical and neuroendocrine bases of the hyperalgesic nocebo effect. J Neurosci 2006; 26:12014-12022. This neuropharmacological study provides evidence for a CCKergic link between anxiety and hyperalgesia in humans.
    • (2006) J Neurosci , vol.26 , pp. 12014-12022
    • Benedetti, F.1    Amanzio, M.2    Vighetti, S.3    Asteggiano, G.4
  • 35
    • 24344458431 scopus 로고    scopus 로고
    • Involvement of cholecystokininergic systems in anxiety-induced hyperalgesia in male rats: Behavioral and biochemical studies
    • Andre J, Zeau B, Pohl M, et al. Involvement of cholecystokininergic systems in anxiety-induced hyperalgesia in male rats: behavioral and biochemical studies. J Neurosci 2005; 25:7896-7904.
    • (2005) J Neurosci , vol.25 , pp. 7896-7904
    • Andre, J.1    Zeau, B.2    Pohl, M.3
  • 36
    • 27944434204 scopus 로고    scopus 로고
    • Cholecystokinin and endogenous opioid peptides: Interactive influence on pain, cognition, and emotion
    • Hebb ALO, Poulin J-F, Roach SP, et al. Cholecystokinin and endogenous opioid peptides: interactive influence on pain, cognition, and emotion. Prog Neuropsychopharmacol Biol Psychiatry 2005; 29:1225-1238.
    • (2005) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 1225-1238
    • Hebb, A.L.O.1    Poulin, J.-F.2    Roach, S.P.3
  • 37
    • 0031316937 scopus 로고    scopus 로고
    • Cholecystokinin type-A and type-B receptors and their modulation of opioid analgesia
    • Benedetti F. Cholecystokinin type-A and type-B receptors and their modulation of opioid analgesia. News Physiol Sci 1997; 12:263-268.
    • (1997) News Physiol Sci , vol.12 , pp. 263-268
    • Benedetti, F.1
  • 38
    • 0032581109 scopus 로고    scopus 로고
    • The contribution of the rostral ventromedial medulla to the antinociceptive effects of systemic morphine in restrained and unrestrained rats
    • Mitchell JM, Lowe D, Fields HL. The contribution of the rostral ventromedial medulla to the antinociceptive effects of systemic morphine in restrained and unrestrained rats. Neuroscience 1998; 87:123-133.
    • (1998) Neuroscience , vol.87 , pp. 123-133
    • Mitchell, J.M.1    Lowe, D.2    Fields, H.L.3
  • 39
    • 0035187315 scopus 로고    scopus 로고
    • Circuitry underlying antiopioid actions of cholecystokinin within the rostral ventromedial medulla
    • Heinricher MM, McGaraughty S, Tortorici V. Circuitry underlying antiopioid actions of cholecystokinin within the rostral ventromedial medulla. J Neurophysiol 2001; 85:280-286.
    • (2001) J Neurophysiol , vol.85 , pp. 280-286
    • Heinricher, M.M.1    McGaraughty, S.2    Tortorici, V.3
  • 40
    • 4444328321 scopus 로고    scopus 로고
    • Neural basis for the hyperalgesic action of cholecystokinin in the rostral ventromedial medulla
    • Heinricher MM, Neubert MJ. Neural basis for the hyperalgesic action of cholecystokinin in the rostral ventromedial medulla. J Neurophysiol 2004; 92:1982-1989.
    • (2004) J Neurophysiol , vol.92 , pp. 1982-1989
    • Heinricher, M.M.1    Neubert, M.J.2
  • 41
    • 0033580975 scopus 로고    scopus 로고
    • Dissociating pain from its anticipation in the human brain
    • Ploghaus A, Tracey I, Gati JS, et al. Dissociating pain from its anticipation in the human brain. Science 1999; 284:1979-1981.
    • (1999) Science , vol.284 , pp. 1979-1981
    • Ploghaus, A.1    Tracey, I.2    Gati, J.S.3
  • 42
    • 0034307470 scopus 로고    scopus 로고
    • Expectation of pain enhances responses to nonpainful somatosensory stimulation in the anterior cingulated cortex and parietal operculum/posterior insula: An event-related functional magnetic resonance imaging study
    • Sawamoto N, Honda M, Okada T, et al. Expectation of pain enhances responses to nonpainful somatosensory stimulation in the anterior cingulated cortex and parietal operculum/posterior insula: an event-related functional magnetic resonance imaging study. J Neurosci 2000; 20:7438-7445.
    • (2000) J Neurosci , vol.20 , pp. 7438-7445
    • Sawamoto, N.1    Honda, M.2    Okada, T.3
  • 43
    • 0037092435 scopus 로고    scopus 로고
    • Does anticipation of pain affect cortical nociceptive systems?
    • Porro CA, Baraldi P, Pagnoni G, et al. Does anticipation of pain affect cortical nociceptive systems? J Neurosci 2002; 22:3206-3214.
    • (2002) J Neurosci , vol.22 , pp. 3206-3214
    • Porro, C.A.1    Baraldi, P.2    Pagnoni, G.3
  • 45
    • 20444362053 scopus 로고    scopus 로고
    • Cortical correlates of false expectations during pain intensity judgments - a possible manifestation of placebo/nocebo cognitions
    • Lorenz J, Hauck M, Paur RC, et al. Cortical correlates of false expectations during pain intensity judgments - a possible manifestation of placebo/nocebo cognitions. Brain Behav Immun 2005; 19:283-295.
    • (2005) Brain Behav Immun , vol.19 , pp. 283-295
    • Lorenz, J.1    Hauck, M.2    Paur, R.C.3
  • 46
    • 33646438994 scopus 로고    scopus 로고
    • Isolating the modulatory effect of expectation on pain transmission: A functional magnetic resonance imaging study
    • This functional magnetic resonance imaging study shows how the level of expected pain intensity alters perceived pain intensity along with the activation of different brain regions
    • Keltner JR, Furst A, Fan C, et al. Isolating the modulatory effect of expectation on pain transmission: a functional magnetic resonance imaging study. J Neurosci 2006; 26:4437-4443. This functional magnetic resonance imaging study shows how the level of expected pain intensity alters perceived pain intensity along with the activation of different brain regions.
    • (2006) J Neurosci , vol.26 , pp. 4437-4443
    • Keltner, J.R.1    Furst, A.2    Fan, C.3
  • 47
    • 0019503181 scopus 로고
    • Analgesic responses to morphine and placebo in individuals with postoperative pain
    • Levine JD, Gordon NC, Smith R, Fields HL. Analgesic responses to morphine and placebo in individuals with postoperative pain. Pain 1981; 10:379-389.
    • (1981) Pain , vol.10 , pp. 379-389
    • Levine, J.D.1    Gordon, N.C.2    Smith, R.3    Fields, H.L.4
  • 48
    • 0035864940 scopus 로고    scopus 로고
    • Response variability to analgesics: A role for nonspecific activation of endogenous opioids
    • Amanzio M, Pollo A, Maggi G, Benedetti F. Response variability to analgesics: a role for nonspecific activation of endogenous opioids. Pain 2001; 90:205-215.
    • (2001) Pain , vol.90 , pp. 205-215
    • Amanzio, M.1    Pollo, A.2    Maggi, G.3    Benedetti, F.4
  • 49
    • 0042384301 scopus 로고    scopus 로고
    • Open versus hidden medical treatments: The patient's knowledge about a therapy affects the therapy outcome
    • Benedetti F, Maggi G, Lopiano L, et al. Open versus hidden medical treatments: the patient's knowledge about a therapy affects the therapy outcome. Prevent Treat 6, 2003. http://content2.apa.org/journals/pre/6/1/1.
    • (2003) Prevent Treat , vol.6
    • Benedetti, F.1    Maggi, G.2    Lopiano, L.3
  • 50
    • 0035864992 scopus 로고    scopus 로고
    • Assessing placebo effects without placebo groups: An untapped possibility?
    • Price DD. Assessing placebo effects without placebo groups: an untapped possibility? Pain 2001; 90:201-203.
    • (2001) Pain , vol.90 , pp. 201-203
    • Price, D.D.1
  • 51
    • 0018887085 scopus 로고
    • Electrophysiological evidence for a release of endogenous opiates in stress-induced analgesia in man
    • Willer JC, Albe-Fessard D. Electrophysiological evidence for a release of endogenous opiates in stress-induced analgesia in man. Brain Res 1980; 198:419-426.
    • (1980) Brain Res , vol.198 , pp. 419-426
    • Willer, J.C.1    Albe-Fessard, D.2
  • 52
    • 0022501592 scopus 로고
    • Opioid and nonopioid stress analgesia from cold water swim: Importance of stress severity
    • Terman GW, Morgan MJ, Liebeskind JC. Opioid and nonopioid stress analgesia from cold water swim: importance of stress severity. Brain Res 1986; 372:167-171.
    • (1986) Brain Res , vol.372 , pp. 167-171
    • Terman, G.W.1    Morgan, M.J.2    Liebeskind, J.C.3
  • 53
    • 0033388018 scopus 로고    scopus 로고
    • Conditioned stress-induced analgesia in humans
    • Flor H, Grusser SM. Conditioned stress-induced analgesia in humans. Eur J Pain 1999; 3:317-324.
    • (1999) Eur J Pain , vol.3 , pp. 317-324
    • Flor, H.1    Grusser, S.M.2


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