The role of placebo and nocebo effects of perioperative administration of sedatives and opioids in interventional pain management

Pain Physician

Volumn 8, Issue 4, 2005, Pages 349-355

  Manchikanti, Laxmaiah ^a,b   Pampati, Vidyasagar ^a   Damron, Kim ^c  

^a PAIN MANAGEMENT CENTER OF PADUCAH   (United States)

^b University of Louisville School of Medicine   (United States)

^c Ambulatory Surgery Center   (United States)

Author keywords

Cervical facet joint pain; Double blind; Fentanyl; Lumbar facet joint pain; Midazolam; Nocebo; Placebo; Randomized; Sedation; Sodium chloride

Indexed keywords

FENTANYL; MIDAZOLAM; OPIATE; PLACEBO; SEDATIVE AGENT; SODIUM CHLORIDE;

ADULT; AGED; ARTICLE; CERVICAL SPINE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE EXACERBATION; DOUBLE BLIND PROCEDURE; DRUG DOSE REGIMEN; FEMALE; HUMAN; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; NERVE BLOCK; NOCEBO EFFECT; PAIN; PAIN ASSESSMENT; PATIENT SATISFACTION; PERIOPERATIVE PERIOD; RANDOMIZED CONTROLLED TRIAL; SEDATION; TREATMENT OUTCOME;

EID: 27944431780     PISSN: 15333159     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (71)

1. Levine JD, Gordon NC, Fields HL. The mechanism of placebo analgesia. Lancet 1978; 2:654-657.
2. Grevert P, Albert LH, Goldstein A. Partial antagonism of placebo analgesia by naloxone. Pain 1983; 16:129-143.
3. Levine JD, Gordon NC. Influence of the method of drug administration on analgesic response. Nature 1984; 312:755-756.
4. Benedetti F. The opposite effects of the opiate antagonist naloxone and the cholecystokinin antagonist proglumide on placebo analgesia. Pain 1996; 64:535-543.
5. Amanzio M, Benedetti F. Neuropharmacological dissection of placebo analgesia: expectation-activated opioid systems versus conditioning-activated specific subsystems. J Neurosci 1999; 19:484-494.
6. Benedetti F, Arduino C, Amanzio M. Somatotopic activation of opioid systems by target-directed expectations of analgesia. J Neurosci 1999; 19:3639-3648.
7. Benedetti F, Pollo A, Lopiano L, Lanotte M, Vighetti S, Rainero I. Conscious expectation and unconscious conditioning in analgesic, motor, and hormonal placebo/nocebo responses. J Neurosci 2003; 23:4315-4323.
8. Petrovic P, Kalso E, Petersson KM, Ingvar M. Placebo and opioid analgesia imaging a shared neuronal network. Science 2002; 295:1737-1740.
9. Haines DR, Wang M, Campion PD, Alladin W. Are patients with chronic widespread pain and/or fatigue nocebo responders? An evaluation employing a randomized crossover trial of proglumide. Pain Clinic 2005; 17:1-13.
10. Price DD, Fields HL. The contribution of desire and expectation to placebo analgesia: Implications for new research strategies. In Harrington A (ed). The Placebo Effect: An Interdisciplinary Exploration. Harvard University Press, Cambridge, MA, 1997, pp 117-137.
11. Price DD, Vase L. Endogenous opioid and non-opioid pathways as mediators of placebo analgesia. In Guess HA, Kleinman A, Kusek JW, Engel LW (eds.) The Science of the Placebo. Toward an Interdisciplinary Research Agenda. BMJ Books, London, 2002, pp 183-206.
12. Laska E, Sunshine A. Anticipation of analgesia. A placebo effect. Headache 1973; 13:1-11.
13. Ader R. The role of conditioning in pharmacotherapy. In Harrington A (ed). The Placebo: An interdisciplinary exploration. Harvard University Press, Cambridge, pp 138-165.
14. Benedetti F, Amanzio M, Baldi S, Casadio C, Maggi G. Inducing placebo respiratory depressant responses in humans via opioid receptors. Eur J Neurosci 1999; 11:625-631.
15. Siegel S. Explanatory mechanisms for placebo effects: Pavlovian conditioning. In Guess HA, Kleinman A, Kusek JW, Engel LW (eds.) The Science of the Placebo: Toward an Interdisciplinary Research Agenda BMJ Books, London, 2002, pp 133-157.
16. Kirsch I, Weixel LJ. Double-blind versus deceptive administration of a placebo. Behav Neurosci 1988; 102:319-323.
17. Kirsch I. How expectancies shape experience. Washington DC, American Psychological Association, 1999.
18. Price DD, Milling LS, Kirsch I, Duff A, Montgomery GH, Nicholls SS. An analysis of factors that contribute to the magnitude of placebo analgesia in an experimental paradigm. Pain 1999; 83:147-156.
19. Pollo A, Amanzio M, Arslanian A, Casadio C, Maggi G, Benedetti F. Response expectancies in placebo analgesia and their clinical relevance. Pain 2001; 93:77-84.
20. Benedetti F, Amanzio M, Casadio C, Oliaro A, Maggi G. Blockade of nocebo hyperalgesia by the cholecystokinin antagonist proglumide. Pain 1997; 71:135-140.
21. Vlaeyen JW, Seelen HA, Peters M, de Jong P, Aretz E, Beisiegel E, Weber WE. Fear of movement/(re)injury and muscular reactivity in chronic low back pain patients: An experimental investigation. Pain 1999; 82:297-304.
22. Turner JA, Jensen MP, Warms CA, Cardenas DD. Blinding effectiveness and association of pretreatment expectations with pain improvement in a double-blind randomized controlled trial. Pain 2002; 99:91-99.
23. Turner JA, Deyo RA, Loeser JD, Von Korff M, Fordyce WE. The importance of placebo effects in pain treatment and research. J Am Med Assoc 1994; 271:1609-1614.
24. Turner JA. Nonspecific treatment effects. In Loeser JD (ed.) Bonica's Management of Pain. Lippincott Williams and Wilkins, Baltimore, 2001, pp 1649-1656.
25. Luparello T, Leist N, Lourie CH, Sweet P. The interaction of psychologic stimuli and pharmacologic agents on airway reactivity in asthmatic subjects. Psychosom Med 1970; 32:509-513.
26. Macdonald A, Peden NR, Hayton R, Mallinson CN, Roberts D, Wormsley KG. Symptom relief and the placebo effect in the trial of an anti-peptic drug. Gut 1980; 21:323-326.
27. Safren SA, Heimberg RG, Juster HR. Clients' expectancies and their relationship to pretreatment symptomatology and outcome of cognitive behavioral group treatment for social phobia. J Consult Clin Psychol 1997; 65:694-698.
28. Shapiro AP, Myers T, Reiser MF, Ferris EB. Comparison of blood pressure response to Verloid and to the doctor. Psychosom Med 1954; 16:478-488.
29. Gracely RH, Dubner R, Deeter WR, Wolskee PJ. Clinicians' expectations influence placebo analgesia. Lancet 1985; 1:8419.
30. Galer BS, Schwartz L, Turner JA. Do patient and physician expectations predict response to pain-relieving procedures? Clin J Pain 1997; 13:348-351.
31. Kalauokalani D, Cherkin DC, Sherman KJ, Koepsell TD, Deyo RA. Lessons from a trial of acupuncture and massage for low back pain. Spine 2001; 26:1418-1424.
32. Fukui S, Ohseto K, Shiotani M, Ohno K, Karasawa H, Naganuma Y, Yuda Y. Referred pain distribution of the cervical zygapophyseal joints and cervical dorsal rami. Pain 1996; 68:79-83.
33. Dwyer A, Aprill C, Bogduk N. Cervical zygapophyseal joint pain patterns: A study in normal volunteers. Spine 1990; 15:453-457.
34. Aprill C, Dwyer A, Bogduk N. The prevalence of cervical zygapophyseal joint pain patterns II: A clinical evaluation. Spine 1990; 15:458-461.
35. Pawl RP. Headache, cervical spondylosis, and anterior cervical fusion. Surg Ann 1977; 9:391-498.
36. Windsor RE, Nagula D, Storm S. Electrical stimulation induced cervical medial branch referral patterns. Pain Physician 2003; 6:411-418.
37. Dreyfuss P, Tibiletti C, Dreyer SJ. Thoracic zygapophyseal joint pain patterns: A study in normal volunteers. Spine 1994; 19:807-811.
38. Mooney V, Robertson J. The facet syndrome. Clin Orthop 1976; 115:149-156.
39. McCall IW, Park WM, O'Brien JP. Induced pain referral from posterior elements in normal subjects. Spine 1979; 4:441-446.
40. Marks R. Distribution of pain provoked from lumbar facet joints and related structures during diagnostic spinal infiltration. Pain 1989; 39:37-40.
41. Fukui S, Ohseto K, Shiotani M, Ohno K, Karasawa H, Naganuma Y. Distribution of referral pain from the lumbar zygapophyseal joints and dorsal rami. Clin J Pain 1997; 13:303-307.
42. Hirsch C, Ingelmark BE, Miller M. The anatomical basis for low back pain. Acta Orthop Scand 1963; 33:1-17.
43. Windsor RE, King FJ, Roman SJ, Tata N, Cone-Sullivan LA, Thampi S, Acebey M, Gilhool JJ, Rao R, Sugar R. Electrical stimulation induced lumbar medial branch referral patterns. Pain Physician 2002; 5: 347-353.
44. Merskey H, Bogduk N. Classification of Chronic Pain: Descriptions of Chronic Pain Syndromes and Definitions of Pain Terms, Second Edition, IASP Press, Seattle, 1994.
45. Manchikanti L, Singh V, Pampati VS, Damron K, Barnhill R, Beyer C, Cash K. Evaluation of the relative contributions of various structures in chronic low back pain. Pain Physician 2001; 4:308-316.
46. Schwarzer AC, Aprill CN, Derby R, Fortin J, Kine G, Bogduk N. Clinical features of patients with pain stemming from the lumbar zygapophysial joints. Is the lumbar facet syndrome a clinical entity? Spine 1994; 19: 1132-1137.
47. Schwarzer AC, Aprill CN, Derby R, Fortin J, Kine G, Bogduk N. The relative contributions of the disc and zygapophyseal joint in chronic low back pain. Spine 1994; 19: 801-806.
48. Schwarzer AC, Wang SC, Bogduk N, McNaught PJ, Laurent R. Prevalence and clinical features of lumbar zygapophysial joint pain: A study in an Australian population with chronic low back pain. Am Rheum Dis 1995; 54:100-106.
49. Manchikanti L, Pampati VS, Fellows B, Bakhit C. Prevalence of lumbar facet joint pain in chronic low back pain. Pain Physician 1999; 2:59-64.
50. Manchikanti L, Pampati VS, Fellows B, Bakhit CE. The diagnostic validity and therapeutic value of medial branch blocks with or without adjuvants agents. Curr Rev Pain 2000; 4:337-344.
51. Manchikanti L, Pampati VS, Fellows B, Baha AG. The inability of the clinical picture to characterize pain from facet joints. Pain Physician 2000; 3:158-166.
52. Manchikanti L, Boswell MV, Singh V, Pampati VS, Damron KS, Beyer CD. Prevalence of facet joint pain in chronic spinal pain of cervical, thoracic, and lumbar regions. BMC Musculoskelet Disord 2004; 5:15.
53. Manchikanti L, Hirsch JA, Pampati VS. Chronic low back pain of facet (zygapophysial) joint origin: is there a difference based on involvement of single or multiple spinal regions? Pain Physician 2003; 6: 399-405.
54. Manchikanti L, Singh V, Pampati V, Damron K, Beyer C, Barnhill R. Is there correlation of facet joint pain in lumbar and cervical spine? Pain Physician 2002; 5:365-371.
55. Barnsley L, Lord SM, Wallis BJ, Bogduk N. The prevalence of chronic cervical zygapophyseal joint pain after whiplash. Spine 1995; 20:20-26.
56. Lord SM, Barnsley L, Wallis BJ, Bogduk N. Chronic cervical zygapophysial joint pain with whiplash: A placebo-controlled prevalence study. Spine 1996; 21:1737-1745.
57. Manchikanti L, Singh V, Rivera J, Pampati VS. Prevalence of cervical facet joint pain in chronic neck pain. Pain Physician 2002; 5:243-249.
58. Manchikanti L, Singh, V, Pampati VS, Beyer C, Damron K. Evaluation of the prevalence of facet joint pain in chronic thoracic pain. Pain Physician 2002; 5:354-359.
59. Bogduk N, Lord S. Cervical zygapophysial joint pain. Neurosurg Q 1998; 8:107-117.
60. Lord SM, Barnsley L, Bogduk N. The utility of comparative local anesthetic blocks versus placebo-controlled blocks for the diagnosis of cervical zygapophysial joint pain. Clin J Pain 1995; 11:208-213.
61. Barnsley L, Lord S, Bogduk N. Comparative local anesthetic blocks in the diagnosis of cervical zygapophysial joints pain. Pain 1993; 55:99-106.
62. Schwarzer AC, Aprill CN, Derby R, Fortin J, Kine G, Bogduk N. The false-positive rate of uncontrolled diagnostic blocks of the lumbar zygapophyseal joints. Pain 1994; 58:195-200.
63. Sehgal N, Shah RV, McKenzie-Brown AM, Everett CR. Diagnostic utility of facet (zygapophysial) joint injections in chronic spinal pain: A systematic review of evidence. Pain Physician 2005; 8: 211-224.
64. Manchikanti L, Damron KS, Rivera J, McManus CD, Jackson SD, Barnhill RC, Martin JC. Evaluation of effect of sedation as a confounding factor in the diagnostic validity of lumbar facet joint pain: A prospective, randomized, double-blind, placebo-controlled evaluation. Pain Physician 2004; 7:407-410.
65. Manchikanti L, Pampati VS, Damron KS, McManus CD, Jackson SD, Barnhill RC, Martin JC. A randomized, prospective, double-blind, placebo-controlled evaluation of the effect of sedation on diagnostic validity of cervical facet joint pain. Pain Physician 2004; 7:301-310.
66. Shah RV, Kaye AD. Evolving concepts in the understanding of cervical facet joint pain. Pain Physician 2004; 7:295-299.
67. Wager TD, Rilling JK, Smith EE, Sokolik A, Casey KL, Davidson RJ, Kosslyn SM, Rose RM, Cohen JD. Placebo-induced changes in FMRI in the anticipation and experience of pain. Science 2004; 303:1162-1167.
68. Finniss DG, Benedetti F. Mechanisms of the placebo response and their impact on clinical trials and clinical practice. Pain 2005; 114:3-6.
69. Amanzio M, Pollo A, Maggi G, Benedetti F. Response variability to analgesics: a role for non-specific activation of endogenous opioids. Pain 2001; 90:205-215.
70. Skrabanek P. Naloxone and placebo. Lancet 1978; 2:791.
71. Kissel P, Barrucand D. Placébos et Effet-Placébo en Médecine. Masson: Paris, 1974.