Amylin and its relation to insulin and lipids in obese children before and after weight loss

Obesity

Volumn 15, Issue 8, 2007, Pages 2006-2011

  Reinehr, Thomas ^a   De Sousa, Gideon ^a   Niklowitz, Petra ^a   Roth, Christian L ^b  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Gastroenterology; GI hormones

Indexed keywords

AMYLIN; AMYLOID; CHOLESTEROL; INSULIN; LIPID; TRIACYLGLYCEROL;

ARTICLE; BLOOD; BODY COMPOSITION; CHILD; CROSS-SECTIONAL STUDY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN RESISTANCE; LONGITUDINAL STUDY; MALE; METABOLISM; OBESITY; PHYSIOLOGY; SKINFOLD THICKNESS; WEIGHT REDUCTION;

AMYLOID; BLOOD GLUCOSE; BODY COMPOSITION; CHILD; CHOLESTEROL; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INSULIN; INSULIN RESISTANCE; LIPIDS; LONGITUDINAL STUDIES; MALE; OBESITY; SKINFOLD THICKNESS; TRIGLYCERIDES; WEIGHT LOSS;

EID: 34548659742     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2007.239     Document Type: Article

References (27)

1. Reda TK, Geliebter A, Pi-Sunyer FX. Amylin, food intake, and obesity. Obes Res. 2002;10:1087-91.
2. Cancello R, Tounian A, Poitou Ch, Clement K. Adiposity signals, genetic and body weight regulation in humans. Diabetes Metab. 2004;30:215-27.
3. Cooper GJ, Willis AC, Clark A, Turner RC, Sim RB, Reid KB. Purification, characterization of a peptide from amyloidrich pancreases of type 2 diabetic patients. Proc Natl Acad Sci USA. 1987;84:8628-32.
4. Young A, Denaro M. Roles of amylin in diabetes and in regulation of nutrient load. Nutrition. 1998;14:524-7.
5. Geary N. Effects of glucagon, insulin, amylin and CGRP on feeding. Neuropeptides, 1999;33:400-5.
6. Rushing PA, Hagan MM, Seeley RJ, et al. Inhibition of central amylin signaling increases food intake and body adiposity in rats. Endocrinology. 2001;142:5035.
7. Morley JE, Flood JF. Amylin decreases food intake in mice. Peptides. 1991;12:865-9.
8. Banks WA, Kastin AJ. Differential permeability of the blood-brain barrier to two pancreatic peptides: insulin and amylin. Peptides. 1998;19:883-9.
9. Kong MF, King P, Macdonald IA, et al. Infusion of pramlintide, a human amylin analogue, delays gastric emptying in men with IDDM. Diabetologia. 1997;40:82-8.
10. Pieber TR, Stein DT, Ogawa A, et al. Amylin-insulin relationships in insulin resistance with and without diabetic hyperglycemia. Am J Physiol. 1993;265:E446-53.
11. Reinehr T, Kiess W, Kapellen T, Andler W. Insulin sensitivity in obese children and adolescents according to degree of weight loss. Pediatrics. 2004;114:1569-73.
12. Smith D, Mamo JC. Islet amyloid polypeptide (amylin) modulates chylomicron metabolism in rats. Clin Exp Pharmacol Physiol. 2000;27:345-51.
13. Leighton B, Cooper GJ. Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro. Nature. 1988;335:632-5.
14. Mather KJ, Paradisi G, Learning R, et al. Role of amylin in insulin secretion and action in humans: antagonist studies across the spectrum of insulin sensitivity. Diabetes Metab Res Rev. 2002;18:118-26.
15. Ye JM, Lim-Fraser M, Cooney GJ, et al. Evidence that amylin stimulates lipolysis in vivo: a possible mediator of induced insulin resistance. Am J Physiol Endocrinol Metab. 2001;280:E562-9.
16. Reinehr T, de Sousa G, Toschke M, Andler W. Long-term follow-up of cardiovascular disease risk factors in obese children after intervention. Am J Clin Nutr. 2006;84:490-6.
17. Reinehr T, Kersting M, Alexy U, Andler W. Long-term follow-up of overweight children: after training, after a single consultation session and without treatment. J Pediatr Gastroenterol Nutr. 2003;37:72-4.
18. Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ. 2000;320:1-6.
19. Kromeyer-Hauschild K, Wabitsch M, Geller F, et al. Percentiles of body mass index in children and adolescents evaluated from different regional German studies. Monatsschr Kinderheilkd. 2001;149:807-18.
20. Cole TJ. The LMS method for constructing normalized growth standards. Eur J Clin Nutr. 1990;44:45-60.
21. Slaughter MH, Lohman TG, Boileau RA, et al. Skinfold equations for estimation of body fatness in children and youth. Hum Biol. 1988;60:709-23.
22. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985;28:412-9.
23. Reinehr T, Andler W. Changes in the atherogenic risk- factor profile according to degree of reduction of overweight. Arch Dis Child. 2004;89:419-22.
24. Reinehr T, de Sousa G, Andler W. Longitudinal analyses between overweight, insulin resistance, and cardiovascular risk factors in children. Obes Res. 2005;13:1824-33.
25. Ludvik B, Kautzky-Willer A, Prager R, Thomaseth K, Pacini G. Amylin: history and overview. Diabet Med. 1997; 14(suppl):9-13.
26. Butler PC, Chou J, Carter WB, et al. (1990) Effects of meal ingestion on plasma amylin concentration in NIDDM and nondiabetic humans. Diabetes. 1990;39:752-6.
27. Wallace TM, Matthews DR. The assessment of insulin resistance in man. Diabet Med. 2002;19:527-34.