Raclopride-induced motor consolidation impairment in primates: Role of the dopamine type-2 receptor in movement chunking into integrated sequences

Experimental Brain Research

Volumn 182, Issue 4, 2007, Pages 499-508

  Levesque, M ^a   Bedard, M A ^a   Courtemanche, R ^b   Tremblay, P L ^a   Scherzer, P ^a   Blanchet, P J ^c  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^b and Applied Physiology   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Dopamine; Motor learning; Primate; Raclopride; Striatum

Indexed keywords

DOPAMINE 2 RECEPTOR; RACLOPRIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CORPUS STRIATUM; LEARNING; MONKEY; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; MOVEMENT (PHYSIOLOGY); NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BEHAVIOR, ANIMAL; CEBUS; DOPAMINE ANTAGONISTS; MEMORY DISORDERS; MENTAL RECALL; MOVEMENT; PSYCHOMOTOR PERFORMANCE; RACLOPRIDE; RECEPTORS, DOPAMINE D2; SERIAL LEARNING;

EID: 34548634050     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-007-1010-4     Document Type: Article

References (48)

1. Ahlenius S, Ericson EL, Hogberg K, Wijkstrom A (1991) Behavioural and biochemical effects of subchronic treatment with raclopride in the rat: tolerance and brain monoamine receptor sensitivity. Pharmacol Toxicol 68:302-309
2. Aldridge JW, Berridge KC (1998) Coding of serial order by neostriatal neurons: a "natural action" approach to movement sequence. J Neurosci 18:2777-2787
3. Bedard MA, Scherer H, Delorimier J, Stip E, Lalonde P (1996) Differential effects of D2- and D4-blocking neuroleptics on the procedural learning of schizophrenic patients. Can J Psychiatry 41:S21-S24
4. Bedard MA, Scherer H, Stip E, Cohen H, Rodriguez JP, Richer F (2000) Procedural learning in schizophrenia: further consideration on the deleterious effect of neuroleptics. Brain Cogn 43:31-39
5. Benecke R, Rothwell JC, Dick JP, Day BL, Marsden CD (1987) Disturbance of sequential movements in patients with Parkinson's disease. Brain 110(Pt 2):361-379
6. Berridge KC, Whishaw IQ (1992) Cortex, striatum and cerebellum: control of serial order in a grooming sequence. Exp Brain Res 90:275-290
7. Brown RG, Marsden CD (1991) Dual task performance and processing resources in normal subjects and patients with Parkinson's disease. Brain 114(Pt 1A):215-231
8. Cools R, Barker RA, Sahakian BJ, Robbins TW (2001) Mechanisms of cognitive set flexibility in Parkinson's disease. Brain 124:2503-2512
9. Cousins MS, Salamone JD (1996) Skilled motor deficits in rats induced by ventrolateral striatal dopamine depletions: behavioral and pharmacological characterization. Brain Res 732:186-194
10. Cromwell HC, Berridge KC (1996) Implementation of action sequences by a neostriatal site: a lesion mapping study of grooming syntax. J Neurosci 16:3444-3458
11. Cronin-Golomb A, Corkin S, Growdon JH (1994) Impaired problem solving in Parkinson's disease: impact of a set-shifting deficit. Neuropsychologia 32:579-593
12. Doyon J, Gaudreau D, Laforce R Jr, Castonguay M, Bedard PJ, Bedard F, Bouchard JP (1997) Role of the striatum, cerebellum, and frontal lobes in the learning of a visuomotor sequence. Brain Cogn 34:218-245
13. Doyon J, Song AW, Karni A, Lalonde F, Adams MM, Ungerleider LG (2002) Experience-dependent changes in cerebellar contributions to motor sequence learning. Proc Natl Acad Sci USA 99:1017-1022
14. Dudai Y (2004) The neurobiology of consolidations, or, how stable is the engram? Annu Rev Psychol 55:51-86
15. Floyer-Lea A, Matthews PM (2005) Distinguishable brain activation networks for short- and long-term motor skill learning. J Neurophysiol 94:512-518
16. Gotham AM, Brown RG, Marsden CD (1988) 'Frontal' cognitive function in patients with Parkinson's disease 'on' and 'off' levodopa. Brain 111(Pt 2):299-321
17. Grafton ST, Mazziotta JC, Presty S, Friston KJ, Frackowiak RS, Phelps ME (1992) Functional anatomy of human procedural learning determined with regional cerebral blood flow and PET. J Neurosci 12:2542-2548
18. Graybiel AM (1998) The basal ganglia and chunking of action repertoires. Neurobiol Learn Mem 70:119-136
19. Harrington DL, Haaland KY, Yeo RA, Marder E (1990) Procedural memory in Parkinson's disease: impaired motor but not visuoperceptual learning. J Clin Exp Neuropsychol 12:323-339
20. Jog MS, Kubota Y, Connolly CI, Hillegaart V, Graybiel AM (1999) Building neural representations of habits. Science 286:1745-1749
21. Jueptner M, Stephan KM, Frith CD, Brooks DJ, Frackowiak RS, Passingham RE (1997) Anatomy of motor learning. I. Frontal cortex and attention to action. J Neurophysiol 77:1313-1324
22. Karni A, Meyer G, Rey-Hipolito C, Jezzard P, Adams MM, Turner R, Ungerleider LG (1998) The acquisition of skilled motor performance: fast and slow experience-driven changes in primary motor cortex. Proc Natl Acad Sci USA 95:861-868
23. Kleim JA, Hogg TM, Vanderberg PM, Cooper NR, Bruneau R, Remple M (2004) Cortical synaptogenesis and motor map reorganization occur during late, but not early, phase of motor skill learning. J Neurosci 21:628-633
24. Koch I, Hoffmann J (2000) Patterns, chunks, and hierarchies in serial reaction-time tasks. Psychol Res 63:22-35
25. Koepp MJ, Gunn RN, Lawrence AD, Cunningham VJ, Dagher A, Jones T, Brooks DJ, Bench CJ, Grasby PM (1998) Evidence for striatal dopamine release during a video game. Nature 393:266-268
26. Kumari V, Corr PJ, Mulligan OF, Cotter PA, Checkley SA, Gray JA (1997) Effects of acute administration of d-amphetamine and haloperidol on procedural learning in man. Psychopharmacology (Berl) 129:271-276
27. Luft AR, Buitrago MM (2005) Stages of motor skill learning. Mol Neurobiol 32:205-216
28. Matsumoto N, Hanakawa T, Maki S, Graybiel AM, Kimura M (1999) Role of [corrected] nigrostriatal dopamine system in learning to perform sequential motor tasks in a predictive manner. J Neurophysiol 82:978-998
29. MacQueen JB (1967) Some methods for classification and analysis of multivariate observations. In: Proceedings of 5-th Berkeley symposium on mathematical statistics and probability, vol 1. University of California Press, Berkeley, pp 281-297
30. Mehta MA, Hinton EC, Montgomery AJ, Bantick RA, Grasby PM (2005) Sulpiride and mnemonic function: effects of a dopamine D2 receptor antagonist on working memory, emotional memory and long-term memory in healthy volunteers. J Psychopharmacol 19:29-38
31. Miller GA (1956) The magical number seven plus or minus two: some limits on our capacity for processing information. Psychol Rev 63:81-97
32. Paquet F, Soucy JP, Stip E, Levesque M, Elie A, Bedard MA (2004) Comparison between olanzapine and haloperidol on procedural learning and the relationship with striatal D2 receptor occupancy in schizophrenia. J Neuropsychiatry Clin Neurosci 16:47-56
33. Penhune VB, Doyon J (2002) Dynamic cortical and subcortical networks in learning and delayed recall of timed motor sequences. J Neurosci 22:1397-1406
34. Purdon SE, Malla A, Labelle A, Lit W (2001) Neuropsychological change in patients with schizophrenia after treatment with quetiapine or haloperidol. J Psychiatry Neurosci 26:137-149
35. Puttemans V, Wenderoth N, Swinnen SP (2005) Changes in brain activation during the acquisition of a multifrequency bimanual coordination task: from the cognitive stage to advanced levels of automaticity. J Neurosci 25:4270-4278
36. Rosa-Neto P, Doudet DJ, Cumming P (2004) Gradients of dopamine D1- and D2/3-binding sites in the basal ganglia of pig and monkey measured by PET. Neuroimage 22:1076-1083
37. Saeedi H, Remington G, Christensen BK (2006) Impact of haloperidol, a dopamine D2 antagonist, on cognition and mood. Schizophr Res 85:222-231
38. Sakai K, Kitaguchi K, Hikosaka O (2003) Chunking during human visuomotor sequence learning. Exp Brain Res 152:229-242
39. Salamone JD, Kurth P, McCullough LD, Sokolowski JD (1995) The effects of nucleus accumbens dopamine depletions on continuously reinforced operant responding: contrasts with the effects of extinction. Pharmacol Biochem Behav 50:437-443
40. Samadi P, Gregoire L, Bedard PJ (2003) Opioid antagonists increase the dyskinetic response to dopaminergic agents in parkinsonian monkeys: interaction between dopamine and opioid systems. Neuropharmacology 45:954-963
41. Sarazin M, Deweer B, Merkl A, Von Poser N, Pillon B, Dubois B (2002) Procedural learning and striatofrontal dysfunction in Parkinson's disease. Mov Disord 17:265-273
42. Scherer H, Bedard MA, Stip E, Paquet F, Richer F, Beriault M, Rodriguez JP, Motard JP (2004) Procedural learning in schizophrenia can reflect the pharmacologic properties of the antipsychotic treatments. Cogn Behav Neurol 17:32-40
43. Schultz W, Romo R (1992) Role of primate basal ganglia and frontal cortex in the internal generation of movements. I. Preparatory activity in the anterior striatum. Exp Brain Res 91:363-384
44. Stelmach GE, Worringham CJ, Strand EA (1987) The programming and execution of movement sequences in Parkinson's disease. Int J Neurosci 36:55-65
45. Tamura I, Kikuchi S, Otsuki M, Kitagawa M, Tashiro K (2003) Deficits of working memory during mental calculation in patients with Parkinson's disease. J Neurol Sci 209:19-23
46. Verwey WB, Eikelboom T (2003) Evidence for lasting sequence segmentation in the discrete sequence-production task. J Mot Behav 35:171-181
47. Wadenberg ML, Kapur S, Soliman A, Jones C, Vaccarino F (2000) Dopamine D2 receptor occupancy predicts catalepsy and the suppression of conditioned avoidance response behavior in rats. Psychopharmacology (Berl) 150:422-429
48. Yaguez L, Lange HW, Homberg V (2006) Differential effect of Huntington's and Parkinson's diseases in programming motor sequences of varied lengths. J Neurol 253:186-193