Progesterone metabolism in bovine endometrial cells and the effect of metabolites on the responsiveness of the cells to OT-stimulation of PGF2α

Steroids

Volumn 72, Issue 13, 2007, Pages 843-850

  Jamshidi, Ahmad A ^a   Girard, Dominique ^a   Beaudry, Francis ^a   Goff, Alan K ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Bovine; Metabolism; Oxytocin; Progesterone; Prostaglandin F2 alpha; Uterus

Indexed keywords

5 ALPHA PREGNANEDIONE; 5 BETA PREGNANEDIONE; OXYTOCIN; PREGNANEDIONE; PREGNENOLONE; PROGESTERONE; PROSTAGLANDIN F2 ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CATTLE; CONTROLLED STUDY; ENDOMETRIUM CELL; ESTRUS CYCLE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PROGESTERONE METABOLISM; PROSTAGLANDIN RELEASE; PROSTAGLANDIN SYNTHESIS;

5-ALPHA-DIHYDROPROGESTERONE; ANIMALS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DINOPROST; ENDOMETRIUM; FEMALE; OXYTOCIN; PREGNENOLONE; PROGESTERONE; RECEPTORS, OXYTOCIN; STROMAL CELLS;

BOVINAE;

EID: 34548621184     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2007.07.005     Document Type: Article

References (38)

1. Poyser N.L. The control of prostaglandin production by the endometrium in relation to luteolysis and menstruation. Prostaglandins Leukot Essent Fatty Acids 53 (1995) 147-195
2. Dubois R.N., Abramson S.B., Crofford L., Gupta R.A., Simon L.S., Van De Putte L.B., et al. Cyclooxygenase in biology and disease. Faseb J 12 (1998) 1063-1073
3. Bazer F.W., Ott T.L., and Spencer T.E. Pregnancy recognition in ruminants, pigs and horses: signals from the trophoblast. Theriogenology 41 (1994) 79-94
4. Asselin E., Goff A.K., Bergeron H., and Fortier M.A. Influence of sex steroids on the production of prostaglandins F2a and E2 and response to oxytocin in cultured epithelial and stromal cells of the bovine endometrium. Biol Reprod 54 (1996) 371-379
5. Kim J.J., and Fortier M.A. Cell type specificity and protein kinase C dependency on the stimulation of prostaglandin E2 and prostaglandin F2 alpha production by oxytocin and platelet-activating factor in bovine endometrial cells. J Reprod Fertil 103 (1995) 239-247
6. McCracken J.A., Schramm W., and Okulicz W.C. Hormone receptor control of pulsatile secretion of PGF2a from the ovine uterus during luteolysis and its abrogation in early pregnancy. Anim Reprod Sci 7 (1984) 31-55
7. Fuchs A.R., Fields M.J., Freidman S., Shemesh M., and Ivell R. Oxytocin and the timing of parturition. Influence of oxytocin receptor gene expression, oxytocin secretion, and oxytocin-induced prostaglandin F2 alpha and E2 release. Adv Exp Med Biol 395 (1995) 405-420
8. Mirando M.A., Becker W.C., and Whiteaker S.S. Relationships among endometrial oxytocin receptors, oxytocin-stimulated phosphoinositide hydrolysis and prostaglandin F2a secretion in vitro, and plasma concentrations of ovarian steroids before and during corpus luteum regression in cyclic heifers. Biol Reprod 48 (1993) 874-882
9. Roberts J.S., McCracken J.A., Gavagan J.E., and Soloff M.S. Oxytocin-stimulated release of prostaglandin F2a from ovine endometrium in vitro: correlation with estrous cycle and oxytocin receptor binding. Endocrinology 99 (1976) 1107-1114
10. Parkinson T.J., Jenner L.J., and Lamming G.E. Comparison of oxytocin/prostaglandin F2a interrelationships in cyclic and pregnant cows. J Reprod Fertil 90 (1990) 337-345
11. Stevenson K.R., Riley P.R., Stewart H.J., Flint A.P., and Wathes D.C. Localization of oxytocin receptor mRNA in the ovine uterus during the oestrous cycle and early pregnancy. J Molec Endocrinol 12 (1994) 93-105
12. Sheldrick E.L., Flick-Smith H.C., and Dos Santos Cruz G.J. Oxytocin receptor binding activity in cultured ovine endometrium. J Reprod Fertil 98 (1993) 521-528
13. Xiao C., and Goff A.K. Hormonal regulation of estrogen and progesterone receptors in cultured bovine endometrial cells. J Reprod Fertil 115 (1999) 101-109
14. Horn S., Bathgate R., Lioutas C., Bracken K., and Ivell R. Bovine endometrial epithelial cells as a model system to study oxytocin receptor regulation. Hum Reprod Update 4 (1998) 605-614
15. Kombe A., Sirois J., and Goff A.K. Prolonged progesterone treatment of endometrial epithelial cells modifies the effect of estradiol on their sensitivity to oxytocin. Steroids 68 (2003) 651-658
16. Leung S.T., and Wathes D.C. Regulatory effect of steroid hormones and fetal tissues on expression of oxytocin receptor in the endometrium of late pregnant ewes. J Reprod Fertil 115 (1999) 243-250
17. Mann G.E. Hormone control of prostaglandin F(2 alpha) production and oxytocin receptor concentrations in bovine endometrium in explant culture. Domest Anim Endocrinol 20 (2001) 217-226
18. Ivell R., Bathgate R.A., Walther N., and Kimura T. The molecular basis of oxytocin and oxytocin receptor gene expression in reproductive tissues. Adv Exp Med Biol 449 (1998) 297-306
19. Redmond A.F., and Pepe G.J. Uterine progesterone metabolism during early pseudopregnancy in the rat. Biol Reprod 35 (1986) 949-955
20. Lisboa B.P., and Holtermann M. Metabolism of progesterone in uterine tissue of non-pregnant rats in vitro. Acta Endocrinol (Copenh) 83 (1976) 583-603
21. Eley R.M., Thatcher W.W., Bazer F.W., and Fields M.J. Steroid metabolism by the bovine uterine endometrium and conceptus. Biol Reprod 28 (1983) 804-816
22. Glasier M.A., Wiebe J.P., and Hobkirk R. Progesterone metabolism by guinea pig intrauterine tissues. J Steroid Biochem Mol Biol 51 (1994) 199-207
23. Sheehan P.M. A possible role for progesterone metabolites in human parturition. Aust N Z J Obstet Gynaecol 46 (2006) 159-163
24. Sheehan P.M., Rice G.E., Moses E.K., and Brennecke S.P. 5Beta-dihydroprogesterone and steroid 5beta-reductase decrease in association with human parturition at term. Mol Hum Reprod 11 (2005) 495-501
25. Ireland J.J., Murphee R.L., and Coulson P.B. Accuracy of predicting stages of bovine estrous cycle by gross appearance of the corpus luteum. J Dairy Sci 63 (1980) 155-160
26. Xiao C., Liu J.M., Sirois J., and Goff A.K. Regulation of cyclooxygenase-2 and prostaglandin F synthase gene expression by steroid hormones and interferon-t in bovine uterine endometrial cells. Endocrinology 139 (1998) 2293-2299
27. Xiao C.W., Murphy B.D., Sirois J., and Goff A.K. Down-regulation of oxytocin-induced cyclooxygenase-2 and prostaglandin f synthase expression by interferon-{tau} in bovine endometrial cells. Biol Reprod 60 (1999) 656-663
28. Redmond A.F. Progesterone and progesterone metabolite concentrations in implantation sites in the pregnant rat. Life Sci 55 (1994) 1863-1870
29. Sun H.S., Hsiao K.Y., Hsu C.C., Wu M.H., and Tsai S.J. Transactivation of steroidogenic acute regulatory protein in human endometriotic stromalcells is mediated by the prostaglandin EP2 receptor. Endocrinology 144 (2003) 3934-3942
30. Tsai S.J., Wu M.H., Lin C.C., Sun H.S., and Chen H.M. Regulation of steroidogenic acute regulatory protein expression and progesterone production in endometriotic stromal cells. J Clin Endocrinol Metab 86 (2001) 5765-5773
31. Ben-Zimra M., Koler M., Melamed-Book N., Arensburg J., Payne A.H., and Orly J. Uterine and placental expression of steroidogenic genes during rodent pregnancy. Mol Cell Endocrinol 187 (2002) 223-231
32. Sweat M.L., and Bryson M.J. Conversion of pregnenolone to progesterone by human endometrium in vitro. Life Sci 8 (1969) 107-111
33. Bryson M.J., and Sweat M.L. Metabolism of progesterone in human proliferative endometrium. Endocrinology 81 (1967) 729-734
34. Collins J.A., and Jewkes D.M. Progesterone metabolism by proliferative and secretory human endometrium. Am J Obstet Gynecol 118 (1974) 179-185
35. Mitchell B.F., Mitchell J.M., Chowdhury J., Tougas M., Engelen S.M., Senff N., et al. Metabolites of progesterone and the pregnane X receptor: a novel pathway regulating uterine contractility in pregnancy?. Am J Obstet Gynecol 192 (2005) 1304-1313
36. Madore E., Harvey N., Parent J., Chapdelaine P., Arosh J.A., and Fortier M.A. An aldose reductase with 20 alpha-hydroxysteroid dehydrogenase activity is most likely the enzyme responsible for the production of prostaglandin F2 alpha in the bovine endometrium. J Biol Chem 278 (2003) 11205-11212
37. Pawlak K.J., Zhang G., and Wiebe J.P. Membrane 5alpha-pregnane-3,20-dione (5alphaP) receptors in MCF-7 and MCF-10A breast cancer cells are up-regulated by estradiol and 5alphaP and down-regulated by the progesterone metabolites, 3alpha-dihydroprogesterone and 20alpha-dihydroprogesterone, with associated changes in cell proliferation and detachment. J Steroid Biochem Mol Biol 97 (2005) 278-288
38. Silvia W.J., Lewis G.S., McCracken J.A., Thatcher W.W., and Wilson Jr. L. Hormonal regulation of uterine secretion of prostaglandin F2a during luteolysis in ruminants. Biol Reprod 45 (1991) 655-663