Association of higher serum calcium levels with smaller infarct volumes in acute ischemic stroke

Archives of Neurology

Volumn 64, Issue 9, 2007, Pages 1287-1291

  Buck, Brian H ^a,b,c   Liebeskind, David S ^b,c   Saver, Jeffrey L ^b,c   Bang, Oh Young ^b,c,d   Starkman, Sidney ^b,c   Ali, Latisha K ^b,c   Kim, Doojin ^b,c   Villablanca, J Pablo ^b   Salamon, Noriko ^b   Yun, Susan W ^b,c   Razinia, Tannaz ^b,c   Ovbiagele, Bruce ^b,c  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Sungkyunkwan University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CALCIUM ION;

ADULT; AGED; ARTICLE; BRAIN INFARCTION SIZE; CALCIUM BLOOD LEVEL; CEREBROVASCULAR ACCIDENT; DIFFUSION WEIGHTED IMAGING; DISEASE MARKER; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NEUROIMAGING; PRIORITY JOURNAL; PROGNOSIS; STROKE;

ACUTE DISEASE; ADULT; AGED; AGED, 80 AND OVER; BRAIN; BRAIN ISCHEMIA; CALCIUM; CEREBRAL INFARCTION; CEREBROVASCULAR ACCIDENT; CROSS-SECTIONAL STUDIES; EXTRACELLULAR SPACE; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES;

EID: 34548603681     PISSN: 00039942     EISSN: 15383687     Source Type: Journal    
DOI: 10.1001/archneur.64.9.1287     Document Type: Article

References (17)

1. Choi DW. Calcium: still center-stage in hypoxic-ischemic neuronal death. Trends Neurosci. 1995;18(2):58-60.
2. 2+ signaling, cell death and stroke. Trends Neurosci. 2006;29(2):75-81.
3. D'Erasmo E, Pisani D, Romagnoli S, Ragno A, Acca M. Acute serum calcium changes in transient ischemic attack and cerebral infarction. J Med. 1998;29(5-6):331-337.
4. Ovbiagele B, Liebeskind DS, Starkman S, et al. Are elevated admission calcium levels associated with better outcomes after ischemic stroke? Neurology. 2006;67(1):170-173.
5. Saver JL, Johnston KC, Homer D, et al; RANTTAS Investigators. Infarct volume as a surrogate or auxiliary outcome measure in ischemic stroke clinical trials. Stroke. 1999;30(2):293-298.
6. Ovbiagele B, Saver JL, Fredieu A, et al. PROTECT: a coordinated stroke treatment program to prevent recurrent thromboembolic events. Neurology. 2004;63(7):1217-1222.
7. Liebeskind DS, Kidwell CS; UCLA Thrombolysis Investigators. Advanced MR imaging of acute stroke: the University of California at Los Angeles endovascular therapy experience. Neuroimaging Clin N Am. 2005;15(2):455-466.
8. Koenker R, Hallock KF. Quantile regression. J Econ Perspect. 2001;15(4):143-156.
9. Frankel MR, Morgenstern LB, Kwiatkowski T, et al. Predicting prognosis after stroke: a placebo group analysis from the National Institute of Neurological Disorders and Stroke rt-PA Stroke Trial. Neurology. 2000;55(7):952-959.
10. Shook SJ, Gupta R, Vora NA, Tievsky AL, Katzan I, Krieger DW. Statin use is independently associated with smaller infarct volume in nonlacunar MCA territory stroke. J Neuroimaging. 2006;16(4):341-346.
11. Adams HP Jr, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke: definitions for use in a multicenter clinical trial. TOAST: Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24(1):35-41.
12. Kidwell CS, Alger JR, Saver JL. Beyond mismatch: evolving paradigms in imaging the ischemic penumbra with multimodal magnetic resonance imaging. Stroke. 2003;34(11):2729-2735.
13. Kristián T, Gidö G, Kuroda S, Schütz A, Siesjö BK. Calcium metabolism of focal and penumbral tissues in rats subjected to transient middle cerebral artery occlusion. Exp Brain Res. 1998;120(4):503-509.
14. Peuler JD, Schelper RL. Partial protection from salt-induced stroke and mortality by high oral calcium in hypertensive rats. Stroke. 1992;23(4):532-538.
15. Iso H, Stampfer MJ, Manson JE, et al. Prospective study of calcium, potassium, and magnesium intake and risk of stroke in women. Stroke. 1999;30(9):1772-1779.
16. Umesawa M, Iso H, Date C, et al. Dietary intake of calcium in relation to mortality from cardiovascular disease: the JACC Study [published online ahead of print December 8, 2005]. Stroke. 2006;37(1):20-26. doi:10.1161/01.STR.0000195155.21143.38.
17. Schaefer PW, Hunter GJ, He J, et al. Predicting cerebral ischemic infarct volume with diffusion and perfusion MR imaging. AJNR Am J Neuroradiol. 2002;23(10):1785-1794.