Influence of chelate conjugation on a newly identified tumor-targeting peptide

Journal of Nuclear Medicine

Volumn 48, Issue 9, 2007, Pages 1545-1552

  Mier, Walter ^a   Zitzmann, Sabine ^a,b,c   Krämer, Susanne ^a   Reed, Jennifer ^b   Knapp, Eva Maria ^a,b   Altmann, Annette ^a,b   Eisenhut, Michael ^b   Haberkorn, Uwe ^a,b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c BAYER PHARMA AG   (Germany)

Author keywords

Biodistribution; Circular dichroism; Peptide structure; Phage display; Pharmacology; Tumor targeting

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; CHELATE; CHELATING AGENT; FROP 1 PEPTIDE; HISTIDYLGLUTAMYLASPARTYLTYROSYLGLUTAMYLLEUCYLMETHIONYLASPARTYLLEUCYLLEUCYLALANYL TYROSYLLEUCYLLYSINAMIDE 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID IN 111; INDIUM 111; UNCLASSIFIED DRUG;

ADDITION REACTION; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING KINETICS; CELL STRAIN MCF 7; CELL TYPE; CHELATION; CIRCULAR DICHROISM; CONJUGATION; CONTROLLED STUDY; FEMALE; HALF LIFE TIME; HEAD AND NECK TUMOR; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; ISOTOPE LABELING; KIDNEY CLEARANCE; KINETICS; LIVER CLEARANCE; MEASUREMENT; MOUSE; NONHUMAN; NUDE MOUSE; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MODIFICATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TARGETING;

ANIMALS; BINDING, COMPETITIVE; CELL LINE, TUMOR; CHELATING AGENTS; FEMALE; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; INDIUM RADIOISOTOPES; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; OLIGOPEPTIDES; PEPTIDES; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 34548598371     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.106.036707     Document Type: Article

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