Capped diaminopropionamide-glycine dipeptides are inhibitors of CC chemokine receptor 2 (CCR2)

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 19, 2007, Pages 5455-5461

  Carter, Percy H ^a   Brown, Gregory D ^a   Friedrich, Sarah R ^a   Cherney, Robert J ^a   Tebben, Andrew J ^a   Lo, Yvonne C ^a   Yang, Gengjie ^a   Jezak, Heather ^a   Solomon, Kimberly A ^a   Scherle, Peggy A ^a   Decicco, Carl P ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Antagonist; CCR2; Chemokine; G protein coupled receptor; Inflammation; Small molecule

Indexed keywords

AMIDE; BENZAMIDE; BENZYLAMINE; CALCIUM; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR3; DIPEPTIDE DERIVATIVE; HYDROGEN; MONOCYTE CHEMOTACTIC PROTEIN 1;

ARTICLE; BINDING AFFINITY; CALCIUM TRANSPORT; CHEMOTAXIS; HUMAN; HUMAN CELL; HYDROGEN BOND; MONOCYTE; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

CALCIUM; CHEMOKINE CCL2; CHEMOTAXIS, LEUKOCYTE; DIPEPTIDES; HYDROGEN BONDING; INDICATORS AND REAGENTS; MOLECULAR CONFORMATION; MONOCYTES; RECEPTORS, CCR2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34548586897     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.07.028     Document Type: Article

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