Molecular and functional expression of anion exchangers in cultured normal human nasal epithelial cells

Acta Physiologica

Volumn 191, Issue 2, 2007, Pages 99-110

  Shin, J H ^a   Son, E J ^b   Lee, H S ^a   Kim, S J ^a   Kim, K ^a   Choi, J Y ^a   Lee, M G ^a   Yoon, J H ^a  

^a Yonsei University College of Medicine   (South Korea)

^b National Medical Center   (South Korea)

Author keywords

Anion exchangers; Cell differentiation; Nasal epithelium

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANION; ANION EXCHANGE PROTEIN 2; ANION EXCHANGE PROTEIN 4; ANTIPORTER; FORSKOLIN; MUCIN 5AC; UNCLASSIFIED DRUG;

ANION EXCHANGE; ARTICLE; CALCIUM SIGNALING; CELL DIFFERENTIATION; CELL STRUCTURE; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; ADENOSINE TRIPHOSPHATE; ANTIPORTERS; BLOTTING, WESTERN; CALCIUM; CELL DIFFERENTIATION; CELLS, CULTURED; CHELATING AGENTS; CILIA; CULTURE MEDIA; CYCLIC AMP; EGTAZIC ACID; FORSKOLIN; GENE EXPRESSION; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, FLUORESCENCE; MUCUS; NASAL MUCOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SODIUM-BICARBONATE SYMPORTERS; STAINING AND LABELING;

EID: 34548585878     PISSN: 17481708     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2007.01731.x     Document Type: Article

References (36)

1. + exchangers in human airways epithelium. J Pancreas 2, 285 290.
2. Alper, S.L. 2006. Molecular physiology of SLC4 anion exchangers. Exp Physiol 91, 153 161.
3. - secretion in a human pancreatic duct cell line (CAPAN-1). J Membr Biol 164, 155 167.
4. Coakley, R.D. Boucher, R.C. 2001. Regulation and functional significance of airway surface liquid pH. JOP 2, 294 300.
5. Coakley, R.D., Grubb, B.R., Paradiso, A.M. et al. 2003. Abnormal surface liquid pH regulation by cultured cystic fibrosis bronchial epithelium. Proc Natl Acad Sci USA 23, 16083 16088.
6. - exchanger isoforms in proximal and distal human airways. Am J Physiol 276, L971 L978.
7. Hunt, J. 2006. Airway acidification: interactions with nitrogen oxides and airway inflammation. Curr Allergy Asthma Rep 6, 47 52.
8. - conductance through CFTR in human airway epithelia. Am J Physiol 272, L752 L761.
9. Inglis, S.K., Finlay, L., Ramminger, S.J. et al. 2002. Regulation of intracellular pH in Calu-3 human airway cells. J Physiol 538, 527 539.
10. Jacquot, J., Puchelle, E., Hinnrasky, J. et al. 1993. A. Localization of the cystic fibrosis transmembrane conductance regulator in airway secretory glands. Eur Respir 6, 169 176.
11. 2+-activated chloride channels in the apical activated membrane of cultured nonciliated human nasal epithelial cells. Am J Physiol Lung Cell Mol Physiol 289, L636 L646.
12. Kim, C.H., Kim, S.S., Choi, J.Y. et al. 2004. Membrane-specific expression of functional purinergic receptors in normal human nasal epithelial cells. Am J Physiol Lung Cell Mol Physiol 287, L835 L842.
13. Kim, C.H., Kim, H.J., Song, K.S. et al. 2005a. MUC8 as a ciliated cell marker in human nasal epithelium. Acta Otolaryngol 125, 76 81.
14. - channel regulated by intracellular pH. J Biol Chem 280, 6463 6470.
15. - exchange in mouse submandibular and pancreatic ducts. J Biol Chem 274, 14670 14677.
16. - exchange by cystic fibrosis transmembrane conductance regulator expressed in NIH 3T3 and HEK 293 cells. Biol Chem 274, 3414 3421.
17. Loffing, J., Moyer, B.D., Reynolds, D., Shmukler, B.E., Alper, S.L. Stanton, B.A. 2000. Functional and molecular characterization of an anion exchanger in airway serous epithelial cells. Am J Physiol Cell Physiol 279, C1016 C1023.
18. Lohi, H., Kujala, M., Makela, S. et al. 2002. Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9. J Biol Chem 277, 14246 14254.
19. Luo, X., Zheng, W., Yan, M., Lee, M.G. Muallem, S. 1999. Multiple functional P2X and P2Y receptors in the luminal and basolateral membranes of pancreatic duct cells. Am J Physiol 277, C205 C215.
20. + channels in human normal and cystic fibrosis airway epithelia. Pediatr Res 53, 608 618.
21. Mount, D.B. Romero, M.F. 2004. The SLC26 gene family of multifunctional anion exchangers. Pflugers Arch 447, 710 721.
22. - transport in pancreatic duct cells. J Biol Chem 278, 200 207.
23. Paradiso, A.M., Ribeiro, C.M. Boucher, R.C. 2001. Polarized signaling via purinoceptors in normal and cystic fibrosis airway epithelia. J Gen Physiol 117, 53 67.
24. - transport in human normal and cystic fibrosis nasal epithelia. J Physiol 548, 203 218.
25. Petruson, B, Hansson, H.A. Karlsson, G. 1984. Structural and functional aspects of cells in the nasal mucociliary system. Arch Otolaryngol 110, 576 581.
26. 2-) transporters: classification, function, structure, genetic diseases, and knockout models. Am J Physiol Renal Physiol 290, F580 F599.
27. Romero, M.F. 2005. Molecular pathophysiology of SLC4 bicarbonate transporters. Curr Opin Nephrol Hypertens 14, 495 501.
28. Smith, J.J. Welsh, M.J. 1992. cAMP stimulates bicarbonate secretion across normal, but not cystic fibrosis airway epithelia. J Clin Invest 89, 1148 1153.
29. --dependent soluble adenylyl cyclase activates cystic fibrosis transmembrane conductance regulator in corneal endothelium. Am J Physiol Cell Physiol 284, C1114 C1122.
30. - potentiates the cAMP-dependent secretory response of the human distal colon through a DIDS-sensitive pathway. Pflugers Arch 442, 256 262.
31. Tos, M. Mogensen, C. 1984. Mucus production in chronic maxillary sinusitis. A quantitative histopathological study. Acta Otolaryngol 97, 151 159.
32. - secretion by Clara cells. Am J Respir Cell Mol Biol 13, 344 351.
33. - exchange activity in tracheal epithelial cells. Am J Physiol Cell Physiol 279, C62 C71.
34. Xie, Q., Welch, R., Mercado, A., Romero, M.F. Mount, D.B. 2002. Molecular characterization of the murine Slc26a6 anion exchanger: functional comparison with Slc26a1. Am J Physiol Renal Physiol 283, F826 F838.
35. Yoon, J.H., Gray, T., Guzman, K., Koo, J.S. Nettesheim, P. 1997. Regulation of the secretory phenotype of human airway epithelium by retinoic acid, triiodothyronine, and extracellular matrix. Am J Respir Cell Mol Biol 16, 724 731.
36. Yoon, J.H., Kim, K.S., Kim, S.S., Lee, J.G. Park, I.Y. 2000. Secretory differentiation of serially passaged normal human nasal epithelial cells by retinoic acid: expression of mucin and lysozyme. Ann Otol Rhinol Laryngol 109, 594 601.