Further study of the Hansenula polymorpha MAL locus: Characterization of the α-glucoside permease encoded by the HpMAL2 gene

FEMS Yeast Research

Volumn 7, Issue 7, 2007, Pages 1134-1144

  Viigand, Katrin ^a   Alamäe, Tiina ^a  

^a UNIVERSITY OF TARTU   (Estonia)

Author keywords

Hansenula polymorpha; Maltose; Maltotriose; Sucrose; Sugar transport; Trehalose

Indexed keywords

4 NITROPHENYL ALPHA DEXTRO GLUCOPYRANOSIDE; ALPHA GLUCOSIDASE; ALPHA GLUCOSIDE PERMEASE; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; DISACCHARIDE; GLUCOPYRANOSIDE; MALTOSE; MALTOTRIOSE; PERMEASE; SUCROSE; TREHALOSE; TURANOSE; UNCLASSIFIED DRUG;

CONFERENCE PAPER; ENZYME ANALYSIS; FUNGAL GENE; GENE LOCUS; HANSENULA POLYMORPHA; HPMAL2 GENE; HYDROLYSIS; MAL GENE; MEMBRANE TRANSPORT; NONHUMAN; PROMOTER REGION; PROTEOMICS; PROTON TRANSPORT;

CARBOHYDRATE METABOLISM; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; FUNGAL PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; GENES, REPORTER; GLUCOSIDES; HYDROGEN-ION CONCENTRATION; MEMBRANE TRANSPORT PROTEINS; MUTAGENESIS, INSERTIONAL; PICHIA; PROMOTER REGIONS, GENETIC; SUBSTRATE SPECIFICITY; TRANS-ACTIVATORS; UNCOUPLING AGENTS;

PICHIA ANGUSTA;

EID: 34548577768     PISSN: 15671356     EISSN: 15671364     Source Type: Journal    
DOI: 10.1111/j.1567-1364.2007.00257.x     Document Type: Conference Paper

References (45)

1. Alamäe T Liiv L (1998) Glucose repression of maltase and methanol-oxidizing enzymes in the methylotrophic yeast Hansenula polymorpha: isolation and study of regulatory mutants. Folia Microbiol 43: 443 452.
2. Alamäe T, Pärn P, Viigand K Karp H (2003) Regulation of the Hansenula polymorpha maltase gene promoter in H. polymorpha and Saccharomyces cerevisiae. FEMS Yeast Res 4: 165 173.
3. Alves-Araujo C, Hernandez-Lopez MJ, Sousa MJ, Prieto JA Randez-Gil F (2004) Cloning and characterization of the MAL11 gene encoding a high-affinity maltose transporter from Torulaspora delbrueckii. FEMS Yeast Res 4: 467 476.
4. Barnett JA (1992) Some controls on oligosaccharide utilization by yeasts: the physiological basis of the Kluyver effect. FEMS Microbiol Lett 79: 371 378.
5. Blandin G, Llorente B, Malpertuy A, Wincker P, Artiguenave F Dujon B (2000) Genomic exploration of the hemiascomycetous yeasts: 13. Pichia angusta. FEBS Lett 487: 76 81.
6. Cheng Q Michels CA (1989) The maltose permease encoded by the MAL61 gene of Saccharomyces cerevisiae exhibits both sequence and structural homology to other sugar transporters. Genetics 123: 477 484.
7. Cheng Q Michels CA (1991) MAL11 and MAL61 encode the inducible high-affinity maltose transporter of Saccharomyces cerevisiae. J Bacteriol 173: 1817 1820.
8. Day RE, Rogers PJ, Dawes IW Higgins VJ (2002) Molecular analysis of maltotriose transport and utilization by Saccharomyces cerevisiae. Appl Environ Microbiol 68: 5326 5335.
9. Elbein AD, Pan YT, Pastuszak I Carroll D (2003) New insights on trehalose: a multifunctional molecule. Glycobiology 13: 17R 27R.
10. Fairhead C Dujon B (2006) Structure of Kluyveromyces lactis subtelomeres: duplications and gene content. FEMS Yeast Res 6: 428 441.
11. Fukuhara H (2003) The Kluyver effect revisited. FEMS Yeast Res 3: 327 331.
12. Goffrini P, Ferrero I Donnini C (2002) Respiration-dependent utilization of sugars in yeasts: a determinant role for sugar transporters. J Bacteriol 184: 427 432.
13. Gonzalez C, Perdomo G, Tejera P, Brito N Siverio JM (1999) One-step, PCR-mediated, gene disruption in the yeast Hansenula polymorpha. Yeast 15: 1323 1329.
14. Han EK, Cotty F, Sottas C, Jiang H Michels CA (1995) Characterization of AGT1 encoding a general alpha-glucoside transporter from Saccharomyces. Mol Microbiol 17: 1093 1107.
15. Hollatz C Stambuk BU (2001) Colorimetric determination of active α-glucoside transport in Saccharomyces cerevisiae. J Microbiol Methods 46: 253 259.
16. Jansen ML, De Winde JH Pronk JT (2002) Hxt-carrier-mediated glucose efflux upon exposure of Saccharomyces cerevisiae to excess maltose. Appl Environ Microbiol 68: 4259 4265.
17. Karp H Alamäe T (1998) Glucose transport in a methylotrophic yeast Hansenula polymorpha. FEMS Microbiol Lett 166: 267 273.
18. Krakenaite RP Glemzha AA (1983) Some properties of two forms of α-glucosidase from Saccharomyces cerevisiae-II. Biokhimija 48: 62 68 (in Russian).
19. Laht S, Karp H, Kotka P, Järviste A Alamäe T (2002) Cloning and characterization of glucokinase from a methylotrophic yeast Hansenula polymorpha: different effects on glucose repression in H. polymorpha and S. cerevisiae. Gene 296: 195 203.
20. Liiv L, Pärn P Alamäe T (2001) Cloning of maltase gene from a methylotrophic yeast Hansenula polymorpha. Gene 26: 77 85.
21. Loureiro-Diaz M Peinado JM (1984) Transport of maltose in Saccharomyces cerevisiae. Biochem J 222: 293 298.
22. Malluta EF, Decker P Stambuk BU (2000) The Kluyver effect for trehalose in Saccharomyces cerevisiae. J Basic Microbiol 40: 199 205.
23. Naumov GI, Naumova ES, Kondratieva VI, Bulat SA, Mironenko NV, Mendonca-Hagler LC Hagler AN (1997) Genetic and molecular delineation of three sibling species in the Hansenula polymorpha complex. Syst Appl Microbiol 20: 50 56.
24. Needleman R (1991) Control of maltase synthesis in yeast. Mol Microbiol 5: 2079 2084.
25. Needleman RB, Federoff HJ, Eccleshall TR, Buchferer B Marmur J (1978) Purification and characterization of an α-glucosidase from Saccharomyces carlsbergensis. Biochemistry 17: 4657 4661.
26. Nwaka S, Mechler B Holzer H (1996) Deletion of the ATH1 gene in Saccharomyces cerevisiae prevents growth on trehalose. FEBS Lett 386: 235 238.
27. Peinado JM, Barbero A van Uden N (1987) Repression and inactivation by glucose of the maltose transport system of Candida utilis. Appl Microbiol Biotechnol 26: 154 157.
28. Ramezani-Rad M, Hollenberg CP, Lauber J et al 2003) The Hansenula polymorpha (strain CBS4732) genome sequencing and analysis. FEMS Yeast Res 4: 207 215.
29. Reinders A Ward JM (2001) Functional characterization of the α-glucoside transporter Sut1p from Schizosaccharomyces pombe, the first fungal homologue of plant sucrose transporters. Mol Microbiol 39: 445 454.
30. Rolim MF, de Araujo PS, Panek AD, Paschoalin VMF Silva JT (2003) Shared control of maltose and trehalose utilization in Candida utilis. Braz J Med Biol Res 36: 829 837.
31. Ryabova EB, Chmil OM Sibirny AA (2003) Xylose and cellobiose fermentation to ethanol by the thermotolerant methylotrophic yeast Hansenula polymorpha. FEMS Yeast Res 4: 157 164.
32. Salema-Oom M, Pinto VV, Goncalves P Spencer-Martins I (2005) Maltotriose utilization by industrial Saccharomyces strains: characterization of a new member of the α-glucoside transporter family. Appl Environ Microbiol 71: 5044 5049.
33. Sambrook J, Fritsch ET Maniatis T (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
34. Serrano R (1977) Energy requirements for maltose transport in yeast. Eur J Biochem 80: 97 102.
35. Sims AP, Kopetzki E, Schulz B Barnett AA (1984) The use of phenolic glycosides for studying the aerobic or anaerobic transport of disaccharides into yeast. J Gen Microbiol 130: 1933 1940.
36. Stambuk BU (2000) A simple laboratory exercise illustrating active transport in yeast cells. Biochem Mol Biol Educ 28: 313 317.
37. Stambuk BU Araujo PS (2001) Kinetics of active α-glucoside transport in Saccharomyces cerevisiae. FEMS Yeast Res 1: 73 78.
38. Stambuk BU, de Araujo PS, Panek A Serrano R (1996) Kinetics and energetics of trehalose transport in Saccharomyces cerevisiae. Eur J Biochem 237: 876 881.
39. + symport in Saccharomyces cerevisiae. Biochim Biophys Acta 1379: 118 128.
40. Stambuk BU, da Silva MA, Panek AD de Araujo PS (1999) Active α-glucoside transport in Saccharomyces cerevisiae. FEMS Microbiol Lett 170: 105 110.
41. Stambuk BU, Batista AS de Araujo PS (2000) Kinetics of active sucrose transport in Saccharomyces cerevisiae. J Biosci Bioeng 89: 212 214.
42. Stasyk OV, Stasyk OG, Komduur J, Veenhuis M, Cregg JM Sibirny AA (2004) A hexose transporter homologue controls glucose repression in the methylotrophic yeast Hansenula polymorpha. J Biol Chem 279: 8116 8125.
43. Van Dijken JP, Otto R Harder W (1976) Growth of Hansenula polymorpha in a methanol-limited chemostat. Physiological responses due to the involvement of methanol oxidase as a key enzyme in methanol metabolism. Arch Microbiol 111: 137 144.
44. Viigand K, Tammus K Alamäe T (2005) Clustering of MAL genes in Hansenula polymorpha: cloning of the maltose permease gene and expression from the divergent intergenic region between the maltose permease and maltase genes. FEMS Yeast Res 5: 1019 1028.
45. Wang X, Bali M, Medintz I Michels CA (2002) Intracellular maltose is sufficient to induce MAL gene expression in Saccharomyces cerevisiae. Eukaryot Cell 1: 696 703.