메뉴 건너뛰기




Volumn 22, Issue 6, 2007, Pages 404-410

Impaired response inhibition in obsessive compulsive disorder

Author keywords

Cognitive inhibition; GO NO GO task; Motor response inhibition; Obsessive compulsive disorder; STOP task; STROOP task

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FEMALE; HUMAN; INTELLIGENCE QUOTIENT; MALE; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; NEUROPSYCHOLOGY; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

EID: 34548576870     PISSN: 09249338     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurpsy.2006.05.001     Document Type: Article
Times cited : (241)

References (62)
  • 2
    • 0037315383 scopus 로고    scopus 로고
    • Horse-race model simulations of the stop-signal procedure
    • Band G.P., Van der Molen M.W., and Logan G.D. Horse-race model simulations of the stop-signal procedure. Acta Psychol 112 2 (2003) 105-142
    • (2003) Acta Psychol , vol.112 , Issue.2 , pp. 105-142
    • Band, G.P.1    Van der Molen, M.W.2    Logan, G.D.3
  • 3
    • 17744376390 scopus 로고    scopus 로고
    • fMRI studies of Stroop tasks reveal unique roles of anterior and posterior brain systems in attentional selection
    • Banich M.T., Milham M.P., Atchley R., Cohen N.J., Webb A., Wszalek T., et al. fMRI studies of Stroop tasks reveal unique roles of anterior and posterior brain systems in attentional selection. J Cognitive Neurosci 12 (2000) 988-1000
    • (2000) J Cognitive Neurosci , vol.12 , pp. 988-1000
    • Banich, M.T.1    Milham, M.P.2    Atchley, R.3    Cohen, N.J.4    Webb, A.5    Wszalek, T.6
  • 4
    • 0036606059 scopus 로고    scopus 로고
    • Response inhibition deficits in obsessive-compulsive disorder
    • Bannon S., Gonsalvez C.J., Croft R.J., and Boyce P.M. Response inhibition deficits in obsessive-compulsive disorder. Psychiatry Res 110 (2002) 165-174
    • (2002) Psychiatry Res , vol.110 , pp. 165-174
    • Bannon, S.1    Gonsalvez, C.J.2    Croft, R.J.3    Boyce, P.M.4
  • 5
    • 0023095954 scopus 로고
    • Local cerebral glucose metabolic rates in obsessive-compulsive disorder: a comparison with rates in unipolar depression in normal controls
    • Baxter L.E., Phelps E.A., Mazziotta J.C., Guze B.H., Schwartz J.M., and Selin C.E. Local cerebral glucose metabolic rates in obsessive-compulsive disorder: a comparison with rates in unipolar depression in normal controls. Arch Gen Psychiat 44 (1987) 211-218
    • (1987) Arch Gen Psychiat , vol.44 , pp. 211-218
    • Baxter, L.E.1    Phelps, E.A.2    Mazziotta, J.C.3    Guze, B.H.4    Schwartz, J.M.5    Selin, C.E.6
  • 7
    • 85068755528 scopus 로고    scopus 로고
    • Specific brain system mediation of obsessive-compulsive disorder responsive to either medication or behavior therapy
    • Goodman W.K., and Rudorfer M.V. (Eds), Lawrence Erlbaum Associates, Inc. Black, H., Mahway, NJ
    • Baxter L.R., Ackermann R.F., Swerdlow N.R., Brody A., Saxena S., Scwartz J.M., et al. Specific brain system mediation of obsessive-compulsive disorder responsive to either medication or behavior therapy. In: Goodman W.K., and Rudorfer M.V. (Eds). Obsessive-compulsive disorder: contemporary issues in treatment (2000), Lawrence Erlbaum Associates, Inc. Black, H., Mahway, NJ 573-609
    • (2000) Obsessive-compulsive disorder: contemporary issues in treatment , pp. 573-609
    • Baxter, L.R.1    Ackermann, R.F.2    Swerdlow, N.R.3    Brody, A.4    Saxena, S.5    Scwartz, J.M.6
  • 10
    • 0030457555 scopus 로고    scopus 로고
    • Functional MRI and the study of OCD: from symptom provocation to cognitive-behavioral probes of cortico-striatal systems and the amygdala
    • Breiter H.C., and Rauch S.L. Functional MRI and the study of OCD: from symptom provocation to cognitive-behavioral probes of cortico-striatal systems and the amygdala. NeuroImage 4 (1996) S127-S138
    • (1996) NeuroImage , vol.4
    • Breiter, H.C.1    Rauch, S.L.2
  • 11
    • 0032549728 scopus 로고    scopus 로고
    • Frontal lobe dysfunction in obsessive-compulsive disorder and major depression: a clinical-neuropsychological study
    • Cavedini P., Ferri S., Scarone S., and Bellodi L. Frontal lobe dysfunction in obsessive-compulsive disorder and major depression: a clinical-neuropsychological study. Psychiatry Res 78 (1998) 21-28
    • (1998) Psychiatry Res , vol.78 , pp. 21-28
    • Cavedini, P.1    Ferri, S.2    Scarone, S.3    Bellodi, L.4
  • 12
    • 16844370542 scopus 로고    scopus 로고
    • The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers
    • Chamberlain S.R., Blackwell A.D., Fineberg B.A., Robbins T.W., and Sahakian B.J. The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers. Neurosci Biobehav Rev 29 (2005) 399-419
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 399-419
    • Chamberlain, S.R.1    Blackwell, A.D.2    Fineberg, B.A.3    Robbins, T.W.4    Sahakian, B.J.5
  • 13
    • 0033009730 scopus 로고    scopus 로고
    • Selective attention in obsessive-compulsive disorder
    • Clayton I.C., Richards J.C., and Edwards C.J. Selective attention in obsessive-compulsive disorder. J Abnorm Psychol 108 (1999) 171-175
    • (1999) J Abnorm Psychol , vol.108 , pp. 171-175
    • Clayton, I.C.1    Richards, J.C.2    Edwards, C.J.3
  • 14
    • 0141615732 scopus 로고    scopus 로고
    • Anxiety and selective attention in obsessive-compulsive disorder
    • Cohen Y., Rasic J., Lachenmeyer I., and Springer C. Anxiety and selective attention in obsessive-compulsive disorder. Behav Res Ther 11 (2003) 1311-1323
    • (2003) Behav Res Ther , vol.11 , pp. 1311-1323
    • Cohen, Y.1    Rasic, J.2    Lachenmeyer, I.3    Springer, C.4
  • 15
    • 0033983512 scopus 로고    scopus 로고
    • The relationship between semantic organization and memory in obsessive-compulsive disorder
    • Deckersbach T., Otto M.W., Savage C.R., Baer L., and Jenike M.A. The relationship between semantic organization and memory in obsessive-compulsive disorder. Psychother Psychosom 69 (2000) 101-107
    • (2000) Psychother Psychosom , vol.69 , pp. 101-107
    • Deckersbach, T.1    Otto, M.W.2    Savage, C.R.3    Baer, L.4    Jenike, M.A.5
  • 18
    • 0027373763 scopus 로고
    • Smooth pursuit and saccadic eye movements and Wisconsin Card Sorting Test performance in obsessive-compulsive disorder
    • Gambini O., Abbruzesse M., and Scarone S. Smooth pursuit and saccadic eye movements and Wisconsin Card Sorting Test performance in obsessive-compulsive disorder. Psychiatry Res 48 (1993) 191-200
    • (1993) Psychiatry Res , vol.48 , pp. 191-200
    • Gambini, O.1    Abbruzesse, M.2    Scarone, S.3
  • 19
    • 0032782299 scopus 로고    scopus 로고
    • Visuospatial priming and Stroop performance in patients with obsessive compulsive disorder
    • Hartston H.J., and Swerdlow N.R. Visuospatial priming and Stroop performance in patients with obsessive compulsive disorder. Neuropsychology 13 (1999) 447-457
    • (1999) Neuropsychology , vol.13 , pp. 447-457
    • Hartston, H.J.1    Swerdlow, N.R.2
  • 20
    • 1642283453 scopus 로고    scopus 로고
    • Reduced response-inhibition in obsessive-compulsive disorder measured with topographic evoked potential mapping
    • Herrman M.J., Jacob C., Unterecker S., and Fallgater J.A. Reduced response-inhibition in obsessive-compulsive disorder measured with topographic evoked potential mapping. Psychiatry Res 120 (2003) 265-271
    • (2003) Psychiatry Res , vol.120 , pp. 265-271
    • Herrman, M.J.1    Jacob, C.2    Unterecker, S.3    Fallgater, J.A.4
  • 21
  • 23
    • 0030598074 scopus 로고    scopus 로고
    • Functional anatomy of GO/NO-GO discrimination and response selection- a PET study in man
    • Kawashima R., Satoh K.M., Ioth H., Ono S., Furumoto S., Gotoh R., et al. Functional anatomy of GO/NO-GO discrimination and response selection- a PET study in man. Brain Res 728 (1996) 79-89
    • (1996) Brain Res , vol.728 , pp. 79-89
    • Kawashima, R.1    Satoh, K.M.2    Ioth, H.3    Ono, S.4    Furumoto, S.5    Gotoh, R.6
  • 24
    • 0038353475 scopus 로고    scopus 로고
    • Neuropsychological correlates of P300 abnormalities in patients with schizophrenia and obsessive-compulsive disorder
    • Kim M.S., Kang S.S., Youn T., Kang D.H., Kim J.J., and Kwon J.S. Neuropsychological correlates of P300 abnormalities in patients with schizophrenia and obsessive-compulsive disorder. Psychiatry Res 123 (2003) 109-123
    • (2003) Psychiatry Res , vol.123 , pp. 109-123
    • Kim, M.S.1    Kang, S.S.2    Youn, T.3    Kang, D.H.4    Kim, J.J.5    Kwon, J.S.6
  • 25
    • 0032919079 scopus 로고    scopus 로고
    • Common inhibitory mechanism in human inferior prefrontal cortex revealed by event-related functional MRI
    • Konishi S., Nakajima K., Uchida I., Kikyo H., and Miyashita Y. Common inhibitory mechanism in human inferior prefrontal cortex revealed by event-related functional MRI. Brain 122 (1999) 981-991
    • (1999) Brain , vol.122 , pp. 981-991
    • Konishi, S.1    Nakajima, K.2    Uchida, I.3    Kikyo, H.4    Miyashita, Y.5
  • 26
    • 0031903763 scopus 로고    scopus 로고
    • No-go dominant brain activity in human inferior prefrontal cortex revealed by functional magnetic resonance imaging
    • Konishi S., Nakajima K., Uchida I., Sekihara K., and Miyashita Y. No-go dominant brain activity in human inferior prefrontal cortex revealed by functional magnetic resonance imaging. Eur J Neurosci 10 (1998) 1209-1213
    • (1998) Eur J Neurosci , vol.10 , pp. 1209-1213
    • Konishi, S.1    Nakajima, K.2    Uchida, I.3    Sekihara, K.4    Miyashita, Y.5
  • 27
    • 0037455301 scopus 로고    scopus 로고
    • Neural correlates of clinical symptoms and cognitive dysfunctions in obsessive-compulsive disorder
    • Kwon J.S., Kim J.J., Lee D.W., Lee J.S., Lee D.S., Kim M.S., et al. Neural correlates of clinical symptoms and cognitive dysfunctions in obsessive-compulsive disorder. Psychiatry Res-Neuroim 122 (2003) 37-47
    • (2003) Psychiatry Res-Neuroim , vol.122 , pp. 37-47
    • Kwon, J.S.1    Kim, J.J.2    Lee, D.W.3    Lee, J.S.4    Lee, D.S.5    Kim, M.S.6
  • 29
    • 0031714214 scopus 로고    scopus 로고
    • Understanding developmental psychopathology: how useful are evolutionary accounts?
    • Leckman J.F., and Mayes L.C. Understanding developmental psychopathology: how useful are evolutionary accounts?. J Am Acad Child Psy 37 (1998) 1011-1021
    • (1998) J Am Acad Child Psy , vol.37 , pp. 1011-1021
    • Leckman, J.F.1    Mayes, L.C.2
  • 31
    • 0030945255 scopus 로고    scopus 로고
    • Caudate regional cerebral blood flow in obsessive-compulsive disorder, panic disorder and healthy controls on single photon emission computerised tomography
    • Lucey J.V., Costa D.C., Busatto G., Pilowsky L.S., Marks I.M., Ell P.J., et al. Caudate regional cerebral blood flow in obsessive-compulsive disorder, panic disorder and healthy controls on single photon emission computerised tomography. Psychiatry Res 14 (Mar 1997) 25-33
    • (1997) Psychiatry Res , vol.14 , pp. 25-33
    • Lucey, J.V.1    Costa, D.C.2    Busatto, G.3    Pilowsky, L.S.4    Marks, I.M.5    Ell, P.J.6
  • 33
    • 0037090411 scopus 로고    scopus 로고
    • Neuropsychological performance in medicated vs. unmedicated patients with obsessive-compulsive disorder
    • Mataix-Cols D., Alonso P., Menchon J.M., and Vallejo J. Neuropsychological performance in medicated vs. unmedicated patients with obsessive-compulsive disorder. Psychiatry Res 109 (2002) 255-256
    • (2002) Psychiatry Res , vol.109 , pp. 255-256
    • Mataix-Cols, D.1    Alonso, P.2    Menchon, J.M.3    Vallejo, J.4
  • 35
    • 0034694189 scopus 로고    scopus 로고
    • Sustained attention in patients with obsessive-compulsive disorder: a controlled study
    • Milliery M., Bouvard M., Aupetit J., and Cottraux J. Sustained attention in patients with obsessive-compulsive disorder: a controlled study. Psychiatry Res 96 (2000) 199-209
    • (2000) Psychiatry Res , vol.96 , pp. 199-209
    • Milliery, M.1    Bouvard, M.2    Aupetit, J.3    Cottraux, J.4
  • 36
    • 0030838241 scopus 로고    scopus 로고
    • Stimulus dimension shifts in patients with schizophrenia, with and without paranoid hallucinatory symptoms, or obsessive compulsive disorder: strategies, blocking and monoamine status
    • Oades R.D. Stimulus dimension shifts in patients with schizophrenia, with and without paranoid hallucinatory symptoms, or obsessive compulsive disorder: strategies, blocking and monoamine status. Behav Brain Res 88 (1997) 115-131
    • (1997) Behav Brain Res , vol.88 , pp. 115-131
    • Oades, R.D.1
  • 38
    • 0032030535 scopus 로고    scopus 로고
    • Cognitive deficits in obsessive-compulsive disorder on tests of frontal-striatal function
    • Purcell R., Maruff P., and Pantelis C. Cognitive deficits in obsessive-compulsive disorder on tests of frontal-striatal function. Biol Psychiatry 43 (1998) 348-357
    • (1998) Biol Psychiatry , vol.43 , pp. 348-357
    • Purcell, R.1    Maruff, P.2    Pantelis, C.3
  • 39
    • 0031862339 scopus 로고    scopus 로고
    • Neuropsychological deficits in obsessive-compulsive disorder: a comparison with unipolar depression, panic disorder, and normal controls
    • Purcell R., Maruff P., and Pantelis C. Neuropsychological deficits in obsessive-compulsive disorder: a comparison with unipolar depression, panic disorder, and normal controls. Arch Gen Psychiat 55 (1998) 415-423
    • (1998) Arch Gen Psychiat , vol.55 , pp. 415-423
    • Purcell, R.1    Maruff, P.2    Pantelis, C.3
  • 44
    • 0035721481 scopus 로고    scopus 로고
    • Mapping motor inhibition: conjunctive brain activations across different versions of go/no-go tasks
    • Rubia K., Russell T., Overmeyer S., Brammer M.J., Bullmore E.T., Sharma T., et al. Mapping motor inhibition: conjunctive brain activations across different versions of go/no-go tasks. NeuroImage 13 (2001) 250-261
    • (2001) NeuroImage , vol.13 , pp. 250-261
    • Rubia, K.1    Russell, T.2    Overmeyer, S.3    Brammer, M.J.4    Bullmore, E.T.5    Sharma, T.6
  • 45
    • 0141535164 scopus 로고    scopus 로고
    • Right inferior prefrontal cortex mediates response inhibition while mesial prefrontal cortex is responsible for error detection
    • Rubia K., Smith A., Brammer M., and Taylor E. Right inferior prefrontal cortex mediates response inhibition while mesial prefrontal cortex is responsible for error detection. NeuroImage 20 (2003) 351-358
    • (2003) NeuroImage , vol.20 , pp. 351-358
    • Rubia, K.1    Smith, A.2    Brammer, M.3    Taylor, E.4
  • 46
    • 34548583989 scopus 로고    scopus 로고
    • Rubia K, Smith A, Taylor E. The Maudsley Attention and Response Suppression Task (MARS) battery: a test battery to measure impulsiveness applied to children with Attention Deficit Hyperactivity Disorder (ADHD). Child Neuropsychol, in press.
  • 48
    • 0033120865 scopus 로고    scopus 로고
    • Organizational strategies mediate non-verbal memory impairment in obsessive-compulsive disorder
    • Savage C.R., Baer L., Keuthen N.J., Brown H.D., Rauch S.L., and Jenike M.A. Organizational strategies mediate non-verbal memory impairment in obsessive-compulsive disorder. Biol Psychiatry 45 (1999) 905-916
    • (1999) Biol Psychiatry , vol.45 , pp. 905-916
    • Savage, C.R.1    Baer, L.2    Keuthen, N.J.3    Brown, H.D.4    Rauch, S.L.5    Jenike, M.A.6
  • 49
    • 0033855659 scopus 로고    scopus 로고
    • Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder
    • Saxena S., and Rauch S.L. Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder. Psychiat Clin North Am 23 (2000) 563-586
    • (2000) Psychiat Clin North Am , vol.23 , pp. 563-586
    • Saxena, S.1    Rauch, S.L.2
  • 50
    • 0032079784 scopus 로고    scopus 로고
    • Hohagen cognitive frontal lobe dysfunction in obsessive-compulsive disorder
    • Schmidtke K., Schorb A., and Winkelmann G. Hohagen cognitive frontal lobe dysfunction in obsessive-compulsive disorder. Biol Psychiatry 43 (1998) 666-673
    • (1998) Biol Psychiatry , vol.43 , pp. 666-673
    • Schmidtke, K.1    Schorb, A.2    Winkelmann, G.3
  • 52
    • 0028707675 scopus 로고
    • An electrophysiological study in obsessional compulsive disorders
    • Serra F.P., Palma V., Nolfe G., and Buscaino G.A. An electrophysiological study in obsessional compulsive disorders. Acta Neurol 16 (1994) 240-248
    • (1994) Acta Neurol , vol.16 , pp. 240-248
    • Serra, F.P.1    Palma, V.2    Nolfe, G.3    Buscaino, G.A.4
  • 53
    • 0028326566 scopus 로고
    • Neurological soft signs in female trichotillomania patients, obsessive-compulsive disorder patients, and healthy control subjects
    • Stein D.J., Hollander E., Simeon D., Cohen L., Islam M.N., and Aronowitz B. Neurological soft signs in female trichotillomania patients, obsessive-compulsive disorder patients, and healthy control subjects. J Neuropsych Clin N 6 (1994) 184-187
    • (1994) J Neuropsych Clin N , vol.6 , pp. 184-187
    • Stein, D.J.1    Hollander, E.2    Simeon, D.3    Cohen, L.4    Islam, M.N.5    Aronowitz, B.6
  • 54
    • 0034254480 scopus 로고    scopus 로고
    • A neural network of obsessive-compulsive disorder: cognitive disinhibition and neurotransmitter dysfunction modelling
    • Stein D.J., and Ludik J. A neural network of obsessive-compulsive disorder: cognitive disinhibition and neurotransmitter dysfunction modelling. Med Hypotheses 55 (2000) 168-176
    • (2000) Med Hypotheses , vol.55 , pp. 168-176
    • Stein, D.J.1    Ludik, J.2
  • 55
    • 0037014867 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder
    • Stein D.J. Obsessive-compulsive disorder. Lancet 360 (2002) 397-405
    • (2002) Lancet , vol.360 , pp. 397-405
    • Stein, D.J.1
  • 56
    • 0032890141 scopus 로고    scopus 로고
    • Obsessive compulsive disorder, checking, and non-verbal memory: a neuropsychological investigation
    • Tallis F., Pratt P., and Jamani N. Obsessive compulsive disorder, checking, and non-verbal memory: a neuropsychological investigation. Behav Res Ther 37 (1998) 161-166
    • (1998) Behav Res Ther , vol.37 , pp. 161-166
    • Tallis, F.1    Pratt, P.2    Jamani, N.3
  • 57
    • 0031040947 scopus 로고    scopus 로고
    • The neuropsychology of obsessive-compulsive disorder: 29review and consideration of clinical implications
    • Tallis F. The neuropsychology of obsessive-compulsive disorder: 29review and consideration of clinical implications. Brit J Clin Psychol 36 (1997) 3-20
    • (1997) Brit J Clin Psychol , vol.36 , pp. 3-20
    • Tallis, F.1
  • 58
    • 0027742252 scopus 로고
    • Visual attention in obsessive-compulsive disorder
    • Terrence E.N., and Haller E.J. Visual attention in obsessive-compulsive disorder. Psychiatry Res 49 (1993) 183-196
    • (1993) Psychiatry Res , vol.49 , pp. 183-196
    • Terrence, E.N.1    Haller, E.J.2
  • 59
    • 0036694449 scopus 로고    scopus 로고
    • Association of QEEG findings with clinical characteristics of OCD: evidence of left frontotemporal dysfunction
    • Tot S., Ozge A., Copmelekoglu U., Yazici K., and Bal N. Association of QEEG findings with clinical characteristics of OCD: evidence of left frontotemporal dysfunction. Can J Psychiat 47 (2002) 538-545
    • (2002) Can J Psychiat , vol.47 , pp. 538-545
    • Tot, S.1    Ozge, A.2    Copmelekoglu, U.3    Yazici, K.4    Bal, N.5
  • 60
    • 0035944658 scopus 로고    scopus 로고
    • A psychophysiological analysis of inhibitory motor control in the stop-signal paradigm
    • Van Boxtel G.J., Van der Molen M.W., Jennings J.R., and Brunia C.H. A psychophysiological analysis of inhibitory motor control in the stop-signal paradigm. Biol Psychol 58 (2001) 229-262
    • (2001) Biol Psychol , vol.58 , pp. 229-262
    • Van Boxtel, G.J.1    Van der Molen, M.W.2    Jennings, J.R.3    Brunia, C.H.4
  • 61
    • 0346995468 scopus 로고    scopus 로고
    • Spatial working memory deficits in obsessive compulsive disorder are associated with excessive engagement of the medial frontal cortex
    • Van der Wee V.M., Ramsey N.F., Jansma J.M., Denys D.A., van Megen H.G., Westenberg H.G., et al. Spatial working memory deficits in obsessive compulsive disorder are associated with excessive engagement of the medial frontal cortex. NeuroImage 20 (2003) 2271-2280
    • (2003) NeuroImage , vol.20 , pp. 2271-2280
    • Van der Wee, V.M.1    Ramsey, N.F.2    Jansma, J.M.3    Denys, D.A.4    van Megen, H.G.5    Westenberg, H.G.6
  • 62
    • 0029803305 scopus 로고    scopus 로고
    • Specific cognitive deficits in tests sensitive to frontal lobe dysfunction in obsessive-compulsive disorder
    • Veale D.M., Sahakian B.J., Owen A.M., and Marks I. Specific cognitive deficits in tests sensitive to frontal lobe dysfunction in obsessive-compulsive disorder. Psychol Med 26 (1996) 1261-1269
    • (1996) Psychol Med , vol.26 , pp. 1261-1269
    • Veale, D.M.1    Sahakian, B.J.2    Owen, A.M.3    Marks, I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.