Hepatitis E virus: A review

Veterinarni Medicina

Volumn 52, Issue 9, 2007, Pages 365-384

  Vasickova, P ^a,b   Psikal, I ^b   Kralik, P ^b   Widen, F ^c   Hubalek, Z ^d,e   Pavlik, Ivo ^b  

^a UNIVERSITY OF VETERINARY AND PHARMACEUTICAL SCIENCES   (Czech Republic)

^b VETERINARY RESEARCH INSTITUTE   (Czech Republic)

^c NATIONAL VETERINARY INSTITUTE   (Sweden)

^d MASARYK UNIVERSITY   (Czech Republic)

^e INSTITUTE OF MATHEMATICS   (Czech Republic)

Author keywords

Food safety; Foodborne viral outbreaks; Pigs; Risk assessment; Zoonoses

Indexed keywords

CERVIDAE; HEPATITIS E VIRUS; HEPEVIRIDAE; HEPEVIRUS; RNA VIRUSES; SUIDAE;

EID: 34548555627     PISSN: 03758427     EISSN: None     Source Type: Journal    
DOI: 10.17221/1999-VETMED     Document Type: Review

References (136)

1. Acha P.N., Szyfres B. (2003): Zoonoses and Communicable Diseases Common to Man and Animals. 3rd ed. Pan American Health Organization, Washington
2. Aggarwal R., Kini D., Sofat S., Naik S.R., Krawczynski K. (2000): Duration of viremia and faecal viral excretion in acute hepatitis. Lancet, 356, 1081-1082
3. Ahn J.M., Kang S.G., Lee D.Y., Shin S.J., Yoo H.S. (2005): Identification of novel human hepatitis E virus (HEV) isolates and determination of the seroprevalence of HEV in Korea. Journal of Clinical Microbiology, 43, 3042-3048
4. Ahn J.M., Rayamajhi N., Kang S.G., Yoo H.S. (2006): Comparison of real-time reverse transcriptasepolymerase chain reaction and nested or commercial reverse transcriptase-polymerase chain reaction for the detection of hepatitis E virus particle in human serum. Diagnostic Microbiology and Infectious Disease, 56, 269-274
5. Anderson D.A., Shrestha I.L. (2002): Clinical Virology, Hepatitis E virus. 2nd ed. ASM Press, American Society for Microbiology, Washington, DC, USA
6. Arankalle V.A., Goverdhan M.K., Banerjee K. (1994): Antibodies against hepatitis E virus in Old World monkeys. Journal of Viral Hepatitis, 1, 125-129
7. Arankalle V.A., Paranjape S., Emerson S.U., Purcell R.H., Walimbe A.M. (1999): Phylogenetic analysis of hepatitis E virus isolates from India (1976-1993). Journal of General Virology, 80, 1691-1700
8. Arankalle V.A., Joshi M.V., Kulkarni A.M., Gandhe S.S., Chobe L.P., Rautmare S.S., Mishra A.C., Padbidri V.S. (2001): Prevalence of anti-HEV antibodies in different Indian animal species. Journal of Viral Hepatitis, 8, 223-227
9. Arankalle V.A., Chobe L.P., Joshi M.V., Chadha M.S., Kundu B., Walimbe A.M. (2002): Human and swine hepatitis E viruses from Western India belong to different genotypes. Journal of Hepatology, 36, 417-425
10. Ashbolt N.J. (2004): Microbial contamination of drinking water and disease outcomes in developing regions. Toxicology, 198, 229-238
11. Balayan M.S. (1997): Epidemiology of hepatitis E virus infection. Journal of Viral Hepatitis, 4, 155-165
12. Balayan M.S., Andzhaparidze A.G., Savinskaya S.S., Ketiladze E.S., Braginsky D.M., Savinov A.P., Poleschuk V.F. (1983): Evidence for virus in non-A/non-B hepatitis transmitted via the faecal-oral route. Intervirology, 20, 23-31
13. Balayan M.S., Usmanov R., Zamyatina N. (1990): Brief report: experimental hepatitis E infection in domestic pigs. Journal of Medical Virology, 32, 58-59
14. Banks M., Heath G.S., Grierson S.S., King D.P., Gresham A., Girones R., Widen F., Harrison T.J. (2004a): Evidence for the presence of hepatitis E virus in pigs in the United Kingdom. Veterinary Record, 154, 223-227
15. Banks M., Bendall R., Grierson S., Heath G., Mitchell J., Dalton H. (2004b): Human and porcine hepatitis E virus strains, United Kingdom. Emerging Infectious Diseases, 10, 953-955
16. Bednar M., Frankova V., Schindler J., Soucek A., Vavra J. (1999): Medical Microbiology (in Czech). 1st ed. (Reissue), Nakladatelstvi Marvil, Prague. 558 pp
17. Berke T., Matson D.O. (2000): Reclassification of the Caliciviridae into distinct genera and exclusion of hepatitis E virus from the family on the basis of comparative phylogenetic analysis. Archives of Virology, 150, 1421-1436
18. Billam P., Huang F.F., Sun Z.F., Pierson F.W., Duncan R.B., Elvinger F., Guenette D.K., Toth T.E., Meng X.J. (2005): Systematic pathogenesis and replication of avian hepatitis E virus in specific-pathogen-free adult chickens. Journal of Virology, 79, 3429-3437
19. Buisson Y., Grandadam M., Nicand E., Cheval P., van Cuyck-Gandre H., Innis B., Rehel P., Coursaget P., Teyssou R., Tsarev S. (2000): Identification of novel hepatitis E virus in Nigeria. Journal of General Virology, 81, 903-909
20. Buti M., Clemente-Casares P., Jardi R., Formiga-Cruz M., Schaper M., Valdes A., Rodriguez-Frias F., Esteban R., Girones R. (2004): Sporadic cases of acute autochthonous hepatitis E in Spain. Journal of Hepatology, 41, 126-131
21. Cacopardo B., Russo R., Preiser W., Benanti F., Brancati G., Nunnari A. (1997): Acute hepatitis E in Catania (eastern Sicily) 1980-1994. The role of hepatitis E virus Infection, 25, 313-316
22. Chatterjee R., Tsarev S., Pillot J., Coursaget P., Emerson S.U., Purcell R.H. (1997): African strains of hepatitis E virus that are distinct from Asian strains. Journal of Medical Virology, 53, 139-144
23. Chauhan A., Jameel S., Dilawari J.B., Chawla Y.K., Kaur U., Ganguly N.K. (1993): Hepatitis E virus transmission to a volunteer. Lancet, 341, 149-150
24. Chobe L.P., Lole K.S., Arankalle V.A. (2006): Full genome sequence and analysis of Indian swine hepatitis E virus isolates of genotype 4. Veterinary Microbiology, 114, 240-251
25. Choi I.S., Kwon H.J., Shin N.R., Yoo H.S. (2003): Identification of swine hepatitis E virus (HEV) and prevalence of anti-HEV antibodies in swine and human populations in Korea. Journal of Clinical Microbiology, 41, 3602-3608
26. Clayson E.T., Myint K.S., Snitbhan R., Vaughn D.W., Innis B.L., Chan L., Cheung P., Shrestha M.P. (1995): Viremia, faecal shedding, and IgM and IgG responses in patients with hepatitis E. Journal of Infectious Diseases, 172, 927-933
27. Cooper K., Huang F.F., Batista L., Rayo C.D., Bezanilla J.C., Toth T.E., Meng X.J. (2005): Identification of genotype 3 hepatitis E virus (HEV) in serum and faecal samples from pigs in Thailand and Mexico, where genotype 1 and 2 HEV strains are prevalent in the respective human populations. Journal of Clinical Microbiology, 43, 1684-1688
28. Dawson G.J., Mushahwar I.K., Chau K.H. (1992): Detection of long-lasting antibody to hepatitis E virus in U. S. traveller to Pakistan. Lancet, 340, 426-427
29. de Deus N., Seminati C., Pina S., Mateu E., Martin M., Segales J. (2006): Detection of hepatitis E virus in liver, mesenteric lymph node, serum, bile and faeces of naturally infected pigs affected by different pathological conditions. Veterinary Microbiology, 119, 105-114
30. Emerson S.U., Purcell R.H. (2003): Hepatitis E virus. Reviews in Medical Virology, 13, 145-154
31. Emerson S.U., Anderson D., Arankalle A.V., Meng X.J., Purdy M., Schlauder G.G., Tsarev S.A. (2004): Hepevirus. In: Fauquet C.M., Mayo M.A., ManiloffJ., Desselberger U., Ball L.A. (eds.): Virus Taxonomy. The Eighth Report of the International Committee on Taxonomy of Viruses. Elsevier/Academic Press, London. 851-855
32. Enouf V., Dos Reis G., Guthmann J.P., Guerin P.J., Caron M., Marechal V., Nicand E. (2006): Validation of single real-time TaqMan® PCR assay for detection and quantisation of four major genotypes of hepatitis E virus in clinical specimens. Journal of Medical Virology, 78, 1076-1082
33. Erker J.C., Desai S.M., Mushahwar I.K. (1999): Rapid detection of hepatitis E virus RNA by reverse transcription-polymerase chain reaction using universal oligonucleotide primers. Journal of Virological Methods, 81, 109-113
34. Favorov M.O., Nazarova O., Margolis H.S. (1998): Is hepatitis E an emerging zoonotic disease? American Journal of Tropical Medicine and Hygiene, 59, 242
35. Favorov M.O., Kosoy M.Y., Tsarev S.A., Childs J.E., Margolis H.S. (2000): Prevalence of antibody to hepatitis E virus among rodents in the United States. Journal of Viral Hepatitis, 8, 223-227
36. Garkavenko O., Obriadina A., Meng J., Anderson D.A., Bernard H.J., Schroeder B.A., Khudyakov Y.E., Fields H.A., Croxson M.C. (2001): Detection and characterisation of swine hepatitis E virus in New Zealand. Journal of Medical Virology, 65, 525-529
37. Ghabrah T.M., Tsarev S.A., Yarbough P.O., Emerson S.U., Strickland G.T., Purcell R.H. (1998): Comparison of tests for antibody to hepatitis E virus. Journal of Medical Virology, 55, 134-137
38. Grimm A.C., Fout G.S. (2002): Development of molecular method to identify hepatitis E virus in water. Journal of Virological Methods, 101, 175-188
39. Halbur P.G., Kasorndorkbua C., Gilbert C., Guenette D., Potters M.B., Purcell R.H., Emerson S.U., Toth T.E., Meng X.J. (2001): Comparative pathogenesis of infection of pigs with hepatitis E viruses recovered from a pig and a human. Journal of Clinical Microbiology, 39, 918-923
40. Haqshenas G., Shivaprasad H.L., Woolcock P.R., Read D.H., Meng X.J. (2001): Genetic identification and characterization of a novel virus related to human hepatitis E virus from chickens with hepatitis-splenomegaly syndrome in the United States. Journal of General Virology, 82, 2449-2462
41. Hirano M., Ding X., Li T.C., Takeda N., Kawabata H., Koizumi N., Kadosaka T., Goto I., Masuzawa T., Nakamura M., Taira K., Kuroki T., Takinawa T., Watanabe H., Abe K. (2003): Evidence for widespread infection of hepatitis E virus among wild rats in Japan. Hepatology Research, 27, 1-5
42. Hsieh S.Y., Yang P.Y., Ho Y.P., Chu C.M., Liaw Y.F. (1998): Identification of a novel strain of hepatitis E virus responsible for sporadic acute hepatitis in Taiwan. Journal of Medical Virology, 55, 300-304
43. Hsieh S.Y., Meng X.J., Wu Y.H., Liu S.T., Tam A.W., Lin D.Y., Liaw Y.F. (1999): Identity of novel swine hepatitis E virus in Taiwan forming a monophyletic group with Taiwan isolates of human hepatitis E virus. Journal of Clinical Microbiology, 37, 3828-3834
44. Huang C.C., Nguyen D., Fernandez J., Yun K.Y., Fry K. E., Bradley D.W., Tam A.W., Reyes G.R. (1992): Molecular cloning and sequencing of the Mexico isolate of hepatitis E virus (HEV). Virology, 191, 550-558
45. Huang F.F., Haqshenas G., Shivaprasad H.L., Guenette D.K., Woolcock P.R., Larsen C.T., Pierson F.W., Elvinger F., Toth T.E., Meng X.J. (2002a): Heterogeneity and seroprevalence of a newly identified avian hepatitis E virus from chicken in the United States. Journal of Clinical Microbiology, 40, 4197-4202
46. Huang F.F., Haqshenas G., Guenette D.K., Halbur P.G., Schommer S.K., Pierson F.W., Toth T.E., Meng X.J. (2002b): Detection by reverse transcription-PCR and genetic characterization of field isolates of swine hepatitis E virus from pigs in different geographic regions of the United States. Journal of Clinical Microbiology, 40, 1326-1332
47. Hubalek Z. (2003): Emerging human infectious diseases: anthroponoses, zoonoses, and sapronoses. Emerging Infectious Diseases, 9, 403-404. http://www.cdc.gov/ncidod/eid/vol9no3/02-0208.htm
48. Hussaini S.H., Skidmore S.J., Richardson P., Sherratt L. M., Cooper B.T., O'Grady J.G. (1997): Severe hepatitis E infection during pregnancy. Journal of Viral Hepatitis, 4, 51-54
49. Inoue J., Takahashi M., Yazaki Y., Tsuda F., Okamoto H. (2006): Development and validation of an improved RT-PCR assay with nested universal primers for detection of hepatitis E virus strains with significant sequence divergence. Journal of Virological Methods, 137, 325-333
50. Jothikumar N., Cromeans T.L., Robertson B.H., Meng X.J., Hill V.R. (2006): A broadly reactive one-step realtime RT-PCR assay for rapid and sensitive detection of hepatitis E virus. Journal of Virological Method, 131, 65-71
51. Kabrane-Lazizi Y., Fine J.B., Elm J., Glass G.E., Higa H., Diwan A., Gibbs C.J., Meng X.J., Emerson S.U., Purcell R.H. (1999a): Evidence for widespread infection of wild rats with hepatitis E virus in the United States. American Journal of Tropical Medicine and Hygiene, 61, 331-335
52. Kabrane-Lazizi Y., Meng X.J., Purcell R.H., Emerson S.U. (1999b): Evidence that the genomic RNA of hepatitis E virus is capped. Journal of Virology, 73, 8848-8850
53. Kasorndorkbua C., Halbur P.G., Thomas P.J., Guenette D.K., Toth T.E., Meng X.J. (2002): Use of a swine bioassay and a RT-PCR assay to assess the risk of transmission of swine hepatitis E virus in pigs. Journal of Virological Methods, 101, 71-78
54. Kawai H.F., Koji T., Iida F., Kaneko S., Kobayashi K., Nakane P.K. (1999): Shift of hepatitis E virus RNA from hepatocytes to biliary epithelial cells during acute infection of rhesus monkey. Journal of Viral Hepatitis, 6, 287-297
55. Khudyakov Y.E., Lopareva E.N., Jue D.L., Crews T.K., Thyagarajan S.P., Fields H.A. (1999): Antigenic domains of the open reading frame 2-encoded protein of hepatitis E virus. Journal of Clinical Microbiology, 37, 2863-2871
56. Khuroo M.S. (1980): Study of an epidemic of non-A, non-B hepatitis: possibility of another human hepatitis virus distinct from posttransfusion non-A, non-B type. American Journal of Medicine, 68, 818-824
57. Khuroo M.S., Kamili S., Jameel S. (1995): Vertical transmission of hepatitis E virus. Lancet, 345, 1025-1026
58. Koonin E.V., Gorbalenya A.E., Purdy M.A., Rozanov M.N., Reyes G.R., Bradley D.W. (1992): Computer-assisted assignment of functional domains in the nonstructural polyprotein of hepatitis E virus: delineation of an additional group of positive-strand RNA plant and animal virus. Proceedings of the National Academy of Sciences, USA, 89, 8259-8263
59. Koopmans M., Duizer E. (2004): Foodborne viruses: an emerging problem. International Journal of Food Microbiology, 90, 23-41
60. Krawczynski K., Bradley D.W. (1989): Enterically-transmitted non-A, non-B hepatitis: identification of virusassociated antigen in experimentally infected cynomolgus macaques. Journal of Infectious Diseases, 159, 1042-1049
61. Kumar A., Beniwal M., Kar P., Sharma J.B., Murthy N.S (2004): Hepatitis E in pregnancy. International Journal of Gynecology and Obstetrics, 85, 240-241
62. Lees D. (2000): Viruses and bivalve shellfish. International Journal of Food Microbiology, 59, 81-116
63. Li F., Zhuang H., Kolivas S., Locarnini S., Anderson D.A. (1994): Persistent and transient antibody responses to hepatitis E virus detected by Western immunoblot using open reading frame 2 and 3 and glutathione Stransferase fusion protein. Journal of Clinical Microbiology, 32, 2060-2066
64. Li T.C., Yakamawa Y., Suzuki K., Tatsumi M., Razak M.A., Uchida T., Takeda N., Miyamura T. (1997): Expression and self-assembly of empty virus-like particles of hepatitis E virus. Journal of Virology, 71, 7207-7213
65. Li T.C., Chijiwa K., Sera N., Ishibashi T., Etoh Y., Shinohara Y., Kurata Y., Ishida M., Sakamoto S., Takeda N., Miyamura T. (2005): Hepatitis E virus transmission from wild boar meat. Emerging Infectious Diseases, 11, 1958-1960
66. Li R.C., Ge S.X., Li Y.P., Zheng Y.J., Nong Y., Guo Q.S., Zhang J., Ng M.H., Xia N.S. (2006a): Seroprevalence of hepatitis E virus infection, rural southern People's Republic of China. Emerging Infectious Diseases, 12, 1682-1688
67. Li T.C., Saito M., Ogura G., Ishibashi I., Miyamura T., Takeda N. (2006b): Serologic evidence for hepatitis E virus infection in mongoose. American Journal of Tropical Medicine and Hygiene, 74, 932-936
68. Lu L., Drobeniuc J., Kobylnikov N., Usmanov R.K., Robertson B.H., Favorov M.O., Margolis H.S. (2004): Complete sequence of Kyrgyzstan swine hepatitis E virus (HEV) isolated from piglet thought to be experimentally infected with human HEV. Journal of Medical Virology, 74, 556-562
69. Lu L., Li C., Hagedorn C.H. (2006): Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis. Review of Medical Virology, 16, 5-36
70. Magden J., Takeda N., Li T., Auvinen P., Ahola T., Miyamura T., Merits A., Kaariainen L. (2001): Virus-specific mRNA capping enzyme encoded by hepatitis E virus. Journal of Virology, 75, 6249-6255
71. Maila H.T., Bowyer S.M., Swanepoel R. (2004): Identification of a new strain of hepatitis E virus from an outbreak in Namibia in 1995. Journal of General Virology, 85, 89-95
72. Mansuy J.M., Peron J.M., Abravanel F., Poirson H., Dubois M., Miedouge M., Vischi F., Alric L., Vinel J.P., Izopet J. (2004): Hepatitis E in the south west of France in individuals who have never visited an endemic area. Journal of Medical Virology, 74, 419-424
73. Mast E.E., Alter M.J., Holland P.V., Purcell R.H. (1998): Evaluation of assays for antibody to hepatitis E virus by a serum panel. Hepatitis E Virus Antibody Serum Panel Evaluation Group. Hepatology, 27, 857-861
74. Masuda J., Yano K., Tamada Y., Takii Y., Ito M., Omagari K., Kohno S. (2005). Acute hepatitis E of a man who consumed wild boar meat prior to the onset of illness in Nagasaki, Japan-Case report. Hepatology Research, 31, 178-183
75. Meng X.J. (2003): Swine hepatitis E virus: Cross-species infection and risk in xenotransplantation. Current Topics in Microbiology and Immunology, 278, 185-216
76. Meng X.J., Purcell R.H., Halbur P.G., Lehman J.R., Webb D.M., Tsareva T.S., Haynes J.S., Thacker B.J., Emerson S.U. (1997): A novel virus in swine is closely related to the human hepatitis E virus. Proceedings of the National Academy of Sciences, USA, 94, 9860-9865
77. Meng X.J., Halbur P.G., Sharipo M.S., Govindarajan S., Bruna J.D., Mushahwar I.K., Purcell R.H., Emerson S.U. (1998a): Genetic and experimental evidence for cross-species infection by the swine hepatitis E virus. Journal of Virology, 72, 9714-9721
78. Meng X.J., Halbur P.G., Tsareva T.S., Bruna J.D., Royer R.L., Purcell R.H., Emerson S.U. (1998b): Experimental infection of pigs with the newly identified swine hepatitis E virus (swine HEV), but not with human strain of HEV. Archives of Virology, 143, 1405-1415
79. Meng X.J., Dea S., Engle R.E., Friendship R., Lyoo Y.S., Sirinarumitr T., Urairong K., Wang D., Wong D., Yoo D., Zhang Y., Purcell R.H., Emerson S.U. (1999): Prevalence of antibodies to the hepatitis E virus in pig from countries where hepatitis E is common or is rare in the human population. Journal of Medical Virology, 59, 297-302
80. Mizuo H., Yazaki Y., Sugawara K., Tsuda F., Takahashi M., Nishizawa T., Okamoto H. (2005): Possible risk factors for the transmission of hepatitis E virus and for the severe form of hepatitis E acquired locally in Hokkaido, Japan. Journal of Medical Virology, 76, 341-349
81. Munne M.S., Vladimirsky S., Otegui L., Castro R., Brajterman L., Soto S., Guarnera E., Molina V., Monfellano M., Schlauder G.G., Gonzalez J.E. (2006): Identification of the first strain of swine hepatitis E virus in South America and prevalence of anti-HEV antibodies in swine in Argentina. Journal of Medical Virology, 78, 1579-1583
82. Nakamura M., Takahashi K., Taira K., Taira M., Ohno A., Sakugawa H., Arai M., Mishiro S. (2006): Hepatitis E virus infection in wild mongooses of Okinawa, Japan: demonstration of anti-HEV antibodies and a full-genome nucleotide sequence. Hepatology Research, 34, 137-140
83. Nicand E., Armstrong G.L., Enouf V., Guthmann J.P., Guerin J.P., Caron M., Nizou J.Y., Andraghetti R. (2005): Genetic heterogeneity of hepatitis E virus in Darfur, Sudan, and neighbouring Chad. Journal of Medical Virology, 77, 519-521
84. Nishizawa T., Takahashi M., Mizuo H., Miyajima H., Gotanda Y., Okamoto H. (2003): Characterization of Japanese swine and human hepatitis E virus isolates of genotype IV with 99% identity over the entire genome. Journal of General Virology, 84, 1245-1251
85. Okamoto H., Takahashi M., Nishizawa T., Fukai K., Muramatsu U., Yoshikawa A. (2001): Analysis of complete genome of indigenous swine hepatitis E virus isolated in Japan. Biochemical and Biophysical Communications, 289, 929-936
86. Okamoto H., Takahashi M., Nishizawa T., Usui R., Kobayashi E. (2004): Presence of antibodies to hepatitis E virus in Japanese pet cats. Infection, 32, 57-58
87. Panda S.K., Ansari I.H., Durgapal H., Agrawal S., Jameel S. (2000): The in vitro-synthesized RNA from a cDNA clone of hepatitis E virus is infectious. Journal of Virology, 74, 2430-2437
88. Payne C.J., Ellis T.M., Plant S.L., Gregory A.R., Wilcox G.E. (1999): Sequence data suggests big liver and spleen disease virus (BLSV) is genetically related to hepatitis E virus. Veterinary Microbiology, 68, 119-125
89. Pina S., Buti M., Cotrina M., Piella J., Girones R. (2000): HEV identified in serum from humans with acute hepatitis and sewage of animal origin in Spain. Journal of Hepatology, 33, 826-833
90. Preiss J.C., Plentz A., Engelmann E., Schneider T., Jilg W., Zeitz M., Duchmann R. (2006): Autochthonous hepatitis E virus infection in Germany with sequence similarities to other European isolates. Infection, 34, 173-175
91. Reuter G., Fodor D., Katai A., Szucs G. (2006): Identification of a novel variant of human hepatitis E virus in Hungary. Journal of Clinical Virology, 36, 100-102
92. Schlauder G.G., Mushahwar I.K. (2001): The genetic heterogeneity of hepatitis E virus. Journal of Medical Virology, 65, 282-292
93. Schlauder G.G., Dawson G.J., Erker J.C., Kwo P.Y., Knigge M.F., Smalley D.L., Rosenblatt J.E., Desai S.M., Mushahwar I.K. (1998): The sequence and phylogenetic analysis of a novel hepatitis E virus isolated from a patient with acute hepatitis reported in the United States. Journal of General Virology, 79, 447-456
94. Schlauder G.G., Desai S.M., Zanetti A.R., Tassopoulos N.C., Mushahwar I.K. (1999): Novel hepatitis E virus (HEV) isolates from Europe: Evidence for additional genotypes of HEV. Journal of Medical Virology, 57, 243-251
95. Schlauder G.G., Frider B., Sookoian S., Castano G.C., Mushahwar I.K. (2000): Identification of 2 novel isolates of hepatitis E virus in Argentina. Journal of Infectious Diseases, 182, 294-297
96. Shrestha S.M., Shrestha S., Tsuda F., Nishizawa T., Gotanda Y., Takeda N., Okamoto H. (2003): Molecular investigation of hepatitis E virus infection in patients with acute hepatitis in Kathmandu, Nepal. Journal of Medical Virology, 69, 207-214
97. Skidmore S.J., Yarbough P.O., Gabor K.A., Tam A.W., Reyes G.R., Flower A.J. (1991): Imported hepatitis E in UK. Lancet, 337, 1541
98. Smith J.L. (2001): A review of hepatitis E virus. Journal of Food Protection, 64, 572-586
99. Sonoda H., Abe M., Sugimoto T., Sato Y., Bando M., Fukui E., Mizuo H., Takahashi M., Nishizawa T., Okamoto H. (2004): Prevalence of hepatitis E virus (HEV) infection in wild boars and deer and genetic identification of a genotype 3 HEV from a boar in Japan. Journal of Clinical Microbiology, 42, 5371-5374
100. Takahashi K., Kitajima N., Abe N., Mishiro S. (2004): Complete or near-complete nucleotide sequences of hepatitis E virus genome recovered from a wild boar, a deer, and four patients who ate the deer. Virology, 330, 501-505
101. Tam A.W., Smith M.M., Guerra M.E., Huang C.C., Bradley D.W., Fry K.E., Reyes G.R. (1991): Hepatitis E virus (HEV): molecular cloning and sequencing of the full-length viral genome. Virology, 185, 120-131
102. Tam A.W., White R., Yarbough P.O., Murphy B.J., McAtee C.P., Lanford R.E., Fuerst T.R. (1997): In vitro infection and replication of hepatitis E virus in primary cynomolgus macaque hepatocytes. Virology, 238, 94-102
103. Tamada Y., Yano K., Yatsuhashi H., Inoue O., Mawatari F., Ishibashi H. (2004): Consumption of wild boar linked to cases of hepatitis E. Journal of Hepatology, 40, 869-870
104. Tei S., Kitajima N., Takahashi K., Mishiro S. (2003): Zoonotic transmission of hepatitis E virus from deer to human beings. Lancet, 362, 371-373
105. Tei S., Kitajima N., Ohara S., Inoue Y., Miki M., Yamatani T., Yamabe H., Mishiro S., Kinoshita Y. (2004): Consumption of uncooked deer meat as a risk factor for hepatitis E virus infection: an age-and sexmatched case-control study. Medical Virology, 74, 67-70
106. Tien N.T., Clayson H.T., Khiem H.B., Sac P.K., Corwin A.L., Myint K.S., Vaughn D.W. (1997): Detection of immunoglobulin G to the hepatitis E virus among several animal species in Vietnam. American Journal of Tropical Medicine and Hygiene, 57, 211
107. Tsarev S.A., Emerson S.U., Reyes G.R., Tsareva T.S., Legters L.J., Malik I.A., Iqbal M., Purcell R.H. (1992): Characterization of a prototype strain of hepatitis E virus. Proceeding of the National Academy of Science, USA, 89, 559-563
108. Tsarev S.A., Tsareva T.S., Emerson S.U., Yarbough P.O., Legters J.L., Moskal T., Purcell R.H. (1994): Infectivity titration of prototype strain of hepatitis E virus in cynomolgus monkeys. Journal of Medical Virology, 43, 135-142
109. Tsarev S.A., Shrestha M.P., He J., Scott R.M., Vaung D. W., Clayson E.T., Gigliotti S., Longer C.F., Innis B.L. (1998): Naturally acquired hepatitis E virus (HEV) infection in Nepalese rodents. American Journal of Tropical Medicine and Hygiene, 59, 242
110. Tsega E., Krawczynski K., Hansson B.G., Nordenfelt E., Negusse Y., Alemu W., Bahru Y. (1991): Outbreak of acute hepatitis E virus infection among military personnel in northern Ethiopia. Journal of Medical Virology, 34, 232-236
111. van Cuyck-Gandre H., Zhang H.Y., Tsarev S.A., Clements N.J., Cohen S.J., Caudill J.D., Buisson Y., Coursaget P., Warren R.L., Longer C.F. (1997): Characterization of hepatitis E virus (HEV) from Algeria and Chad by partial genome sequence. Journal of Medical Virology, 53, 340-347
112. van der Poel W.H.M., Verschoor F., van der Heide R., Herrera M.I., Vivo A., Kooreman M., de Roda Husman A.M. (2001): Hepatitis E virus sequences in swine related to sequences in human, the Netherlands. Emerging Infectious Diseases, 7, 970-976
113. Vasickova P., Dvorska L., Lorencova A., Pavlik I. (2005): Viruses as a cause of foodborne diseases: a review of the literature. Veterinarni Medicina 50, 89-104. http://www.vri.cz/docs/vetmed/50-3-89.pdf
114. Vishwanathan R. (1957): Infectious hepatitis in Delhi (1955-1956): a critical study. Indian Journal of Medical Research, 45, 1-30
115. Vitral C.L., Pito M.A., Lewis-Ximenez L.L., Khudyakov Y.E., dos Santos D.R., Gaspar A.M.C. (2005): Serological evidence of hepatitis E virus infection in different animal species from the Southeast of Brazil. Memorias do Instituto Oswaldo Cruz, 100
116. Waar K., Herremans M.M.P.T., Vennema H., Koopmans M.P.G., Benne C.A. (2005): Hepatitis E is cause of unexplained hepatitis in The Netherlands. Journal of Clinical Virology, 33, 145-149
117. Wang Y.C., Ling R., Erker J.C., Zhang H., Li H., Desai S., Mushahwar I.K., Harrison T.J. (1999): A divergent genotype of hepatitis E virus in Chinese patients with acute hepatitis. Journal of General Virology, 80, 169-177
118. Wang Y.C., Zhang H., Ling R., Li H., Harrison T.J. (2000): The complete sequence of hepatitis E virus genotype 4 reveals an alternative strategy for translation of open reading frames 2 and 3. Journal of General Virology, 81, 1675-1686
119. Wang Y.C., Zhang H.Y., Xia N.S, Peng G., Lan H.Y., Zhuang H., Zhu Y.H., Li S.W., Tian K.G., Gu W.J., Lin J.X., Wu X., Li H.M., Harrison T.J. (2002): Prevalence, isolation, and partial sequence analysis of hepatitis E virus from domestic animals in China. Journal of Medical Virology, 67, 516-521
120. Wei S., Walsh P., Huang R., To S.S.T. (2000): 93G, Novel sporadic strain of hepatitis E virus in South China isolated by cell culture. Journal of Medical Virology, 61, 311-318
121. Wibawa I.D., Muljono D.H., Mulyanto, Suryadarma I. G., Tsuda F., Takahashi M., Nishizawa T., Okamoto H. (2004): Prevalence of antibodies to hepatitis E virus among apparently healthy humans and pigs in Bali, Indonesia: Identification of a pig infected with genotype 4 hepatitis E virus. Journal of Medical Virology, 73, 38-44
122. Widdowson M.A., Jaspers W.J.M., van der Poel W.H.M., Verschoor F., de Roda Husman A.M., Winter H.L.J., Zaaijer H.L., Koopmans M. (2003): Cluster of cases of acute hepatitis associated with hepatitis E virus infection acquired in the Netherlands. Clinical Infectious Disease, 36 1, 29-33
123. Williams T.P.E., Kasorndorkbua C., Halbur P.G., Haqshenas G., Guenette D.K., Toth T.E., Meng X.J. (2001): Evidence of extrahepatic sites of replication of the hepatitis E virus in a swine model. Journal of Clinical Microbiology, 39, 3040-3046
124. Withers M.R., Corea M.T., Morrow M., Stebbins M.E., Seriwatana J., Webster W.D., Boak M.B., Vaughn D.W. (2002): Antibody levels to hepatitis E virus in North Carolina swine workers, non-swine workers, swine, and murids. American Journal of Tropical Medicine and Hygiene, 66 (4), 384-388
125. Worm H.C., Schlauder G.G., Wurzer H., Mushahwar I.K. (2000): Identification of a novel variant of hepatitis E virus in Austria: sequence, phylogenetic and serological analysis. Journal of General Virology, 81, 2885-2890
126. Worm H.C., van der Poel W.H.M., Brandstatter G. (2002): Hepatitis E: an overview. Microbes and Infection, 4, 657-666
127. Wu J.C., Chen C.M., Chiang T.Y., Tsai W.H., Jeng W.J., Sheen I.J., Lin C.C., Meng X.J. (2002): Spread of hepatitis E virus among different-aged pigs: two-year survey in Taiwan. Journal of Medical Virology, 66, 488-492
128. Xing L., Kato K., Li T., Takeda N., Miyamura T., Hammar L., Cheng R.H. (1999): Recombinant hepatitis E capsid protein self-assembles into dual-domain T=1 particle presenting native virus. Virology, 265, 35-45
129. Yarbough P.O. (1999): Hepatitis E virus. Intervirology, 42, 179-184
130. Yazaki Y., Mizuo H., Takahashi M., Nishizawa T., Sasaki N., Gotanda Y., Okamoto H. (2003): Sporadic acute or fulminant hepatitis E in Hokkaido, Japan, may be foodborne, as suggested by the presence of hepatitis E virus in pig liver as food. Journal of General Virology, 84, 2351-2357
131. Yin S., Tsarev S.A., Purcell R.H., Emerson S.U. (1993): Partial sequence comparison of eight new Chinese strains of hepatitis E virus suggests the genome sequence is relatively stable. Journal of Medical Virology, 41, 230-241
132. Yoo D., Willson P., Pei Y., Hayes M.A., Deckert A., Dewey C.E., Friendship R.M., Yoon Y., Gottschalk M., Yason C., Giulivi A. (2001): Prevalence of hepatitis E virus antibodies in Canadian swine herds and identification of novel variant of swine hepatitis E virus. Clinical and Diagnostic Laboratory Immunology, 8, 1213-1219
133. Zafrullah M., Ozdener M.H., Panda S.K., Jameel S. (1997): The ORF3 protein of hepatitis E is phosphoprotein that associates with the cytoskeleton. Journal of Virology, 71, 9045-9053
134. Zafrullah M., Ozdener M.H., Kumar R., Panda S.K., Jameel S. (1999): Mutational analysis of glycosylation, membrane translocation, and cell surface expression of the hepatitis E virus ORF2 protein. Journal of Virology, 73, 4074-4082
135. Zanetti A.R., Schlauder G.G., Romano L., Tanzi E., Fabris P., Dawson G.J., Mushahwar I.K. (1999): Identification of a novel variant of hepatitis E virus in Italy. Journal of Medical Virology, 57, 356-360
136. Zhang M., Purcell R.H., Emerson S.U. (2001): Identification of the terminal sequence of the SAR-55 and MEX-14 strains of hepatitis E virus and confirmation that the genome is capped. Journal of Medical Virology, 65, 293-295