Expression and gene polymorphisms of the chemokine CXCL5 in colorectal cancer patients

International Journal of Oncology

Volumn 31, Issue 1, 2007, Pages 97-102

  Dimberg, Jan ^a   Dienus, Olaf ^b   Löfgren, Sture ^b   Hugander, Anders ^b   Wågsäter, Dick ^c  

^a JÖNKÖPING UNIVERSITY   (Sweden)

^b RYHOV COUNTY HOSPITAL   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Colorectal cancer; CXCL5; IL 1 ; Polymorphism; Tissue level

Indexed keywords

ALPHA CHEMOKINE; CXCL5 PROTEIN, HUMAN; INTERLEUKIN 1BETA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CHEMISTRY; COLORECTAL TUMOR; FEMALE; GENE EXPRESSION; GENETIC POLYMORPHISM; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; MIDDLE AGED; PROTEIN SYNTHESIS;

ADULT; AGED; AGED, 80 AND OVER; CHEMOKINES, CXC; COLORECTAL NEOPLASMS; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PROTEIN BIOSYNTHESIS;

EID: 34548552620     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.31.1.97     Document Type: Article

References (21)

1. Balkwill F and Mantovani A: Inflammation and cancer: back to Virchow? Lancet 357: 539-545, 2001.
2. Coussens LM and Werb Z: Inflammation and cancer. Nature 420: 860-867, 2002.
3. Balkwill F: Chemokine biology in cancer. Semin Immunol 15: 49-55, 2003.
4. Dwinell MB, Johanesen PA and Smith JM: Immunobiology of epithelial chemokines in the intestinal mucosa. Surgery 133: 601-607, 2003.
5. Luster AD: Chemokine regulate lymphocyte homing to the intestinal mucosa. Gastroenterology 120: 291-294, 2001.
6. Keates S, Keates AC, Mizoguchi E, Bhan A and Kelly CP: Enterocytes are the primary source of the chemokine ENA-78 in normal colon and ulcerative colitis. Am J Physiol 273: G75-G82, 1997.
7. Walz A, Schmutz P, Mueller C and Schnyder-Candrian S: Regulation and function of the CXC chemokine ENA-78 in monocytes and its role in disease. J Leukoc Biol 62: 604-611, 1997.
8. Miki C, Tonouchi H, Wakuda R, Hatada T, Inoue Y, Minato E, Kobayashi M and Kusunoki M: Intra-tumoral interleukin-6 downregulation system and genetic mutations of tumor suppressor genes in colorectal cancer. Cancer 94: 1584-1592, 2002.
9. Walz A, Burgener R, Car B, Baggiolini M, Kunkel SL and Strieter RM: Structure and neutrophil-activating properties of a novel inflammatory peptide (ENA-78) with homology of interleukin 8. J Exp Med 174: 1355-1362, 1991.
10. Wen Y, Giardina SF, Hamming D, Greenman J, Zachariah E, Bacolod MD, Liu H, Shia J, Amenta PS, Barany F, Paty P, Gerald W and Notterman D: GRO(alpha) is highly expressed in adenocarcinoma of the colon and down-regulates fibulin-1. Clin Cancer Res 12: 5951-5959, 2006.
11. Strieter RM, Burdick MD, Gomperts BN, Belperio JA and Keane MP: CXC chemokines in angiogenesis. Cytokine Growth Factor Rev 16: 593-609, 2005.
12. Strieter RM, Burdick MD, Mestas J, Gomperts BN, Keane MP and Belperio JA: Cancer CXC chemokine networks and tumour angiogenesis. Eur J Cancer 42: 768-778, 2006.
13. Arenberg DA, Keane MP, DiGiovine B, Kunkel SL, Morris SB, Xue Y-Y, Burdick MD, Glass MC, Iannettoni MD and Strieter RM: Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer. J Clin Invest 102: 465-472, 1998. (Pubitemid 28376148)
14. Rieder G, Einsiedl W, Hatz RA, Stolte M, Enders GA and Walz A: Comparison of CXC chemokines ENA-78 and interleukin-8 expression in Helicobacter pylori-associated gastritis. Infect Immun 69: 81-88, 2001.
15. Z'Graggen K, Walz A, Mazzucchelli L, Strieter RM and Mueller C: The C-X-C chemokine ENA-78 is preferentially expressed in intestinal epithelium in inflammatory bowel disease. Gastroenterology 113: 808-816, 1997.
16. Amoli MM, Larijani B, Thomson W, Ollier WE and Gonzalez-Gay MA: Two polymorphisms in the epithelial cell-derived neutrophil-activating peptide (ENA-78) gene. Dis Markers 21: 75-77, 2005.
17. Zineh I, Welder GJ and Langaee TY: Development and cross-validation of sequencing-based assays for genotyping common polymorphisms of the CXCL5 gene. Clin Chim Acta 370: 72-75, 2006. (Pubitemid 44080174)
18. Zineh I, Aquilante CL, Langaee TY, Beitelshees AL, Arant CB, Wessel TR and Schofield RS: CXCL5 gene polymorphisms are related to systemic concentrations and leukocyte production of epithelial neutrophil-activating peptide (ENA-78). Cytokine 33: 258-263, 2006.
19. Baier PK, Eggstein S, Wolff-Vorbeck G, Baumgartner U and Hopt UT: Chemokines in human colorectal carcinoma. Anticancer Res 25: 3581-3584, 2005.
20. Shokuhi S, Bhatia M, Christmas S, Sutton R, Neoptolemos JP and Slavin J: Levels of the chemokines growth-related oncogene α and epithelial neutrophil-activating protein 78 are raised in patients with severe acute pancreatitis. Br J Surg 89: 566-572, 2002.
21. Wente MN, Keane MP, Burdick MD, Friess H, Buchler MW, Ceyhan GO, Reber HA, Strieter RM and Hines OJ: Blockade of the chemokine receptor CXCR2 inhibits pancreatic cancer cell-induced angiogenesis. Cancer Lett 241: 221-227, 2006.