메뉴 건너뛰기




Volumn 56, Issue 2, 2007, Pages 87-90

Safety pharmacology methods: Anticipating the transition from long QT (LQTS) to short QT syndromes (SQTS)?

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE; BIOLOGICAL MARKER; CHLORPROMAZINE; CLONIDINE; DIAZEPAM; PENTETRAZOLE; QUINIDINE;

EID: 34548550667     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2007.05.003     Document Type: Editorial
Times cited : (8)

References (26)
  • 2
    • 33846627787 scopus 로고    scopus 로고
    • Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death
    • Antzelevitch C., Pollevick G.D., Cordeiro J.M., Casis O., Sanguinetti M.C., Aizawa Y., et al. Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death. Circulation 115 (2007) 442-449
    • (2007) Circulation , vol.115 , pp. 442-449
    • Antzelevitch, C.1    Pollevick, G.D.2    Cordeiro, J.M.3    Casis, O.4    Sanguinetti, M.C.5    Aizawa, Y.6
  • 3
    • 34548487147 scopus 로고    scopus 로고
    • A cardiovascular monitoring system in conscious cynomolgus monkeys for regulatory safety pharmacology: Part 1: Non-pharmacological validation
    • 10.1016/j.vascn.2007.03.010
    • Authier S., Tanguay J.-F., Gauvin D., Di Fruscia R., Fournier S., Chaurand F., and Troncy E. A cardiovascular monitoring system in conscious cynomolgus monkeys for regulatory safety pharmacology: Part 1: Non-pharmacological validation. Journal of Pharmacological & Toxicological Methods 56 (2007) 115-121 10.1016/j.vascn.2007.03.010
    • (2007) Journal of Pharmacological & Toxicological Methods , vol.56 , pp. 115-121
    • Authier, S.1    Tanguay, J.-F.2    Gauvin, D.3    Di Fruscia, R.4    Fournier, S.5    Chaurand, F.6    Troncy, E.7
  • 4
    • 34548496499 scopus 로고    scopus 로고
    • A cardiovascular monitoring system in conscious cynomolgus monkeys for regulatory safety pharmacology: Part 2: Pharmacological validation
    • 10.1016/j.vascn.2007.03.011
    • Authier S., Tanguay J.-F., Gauvin D., Di Fruscia R., and Troncy E. A cardiovascular monitoring system in conscious cynomolgus monkeys for regulatory safety pharmacology: Part 2: Pharmacological validation. Journal of Pharmacological & Toxicological Methods 56 (2007) 122-130 10.1016/j.vascn.2007.03.011
    • (2007) Journal of Pharmacological & Toxicological Methods , vol.56 , pp. 122-130
    • Authier, S.1    Tanguay, J.-F.2    Gauvin, D.3    Di Fruscia, R.4    Troncy, E.5
  • 5
    • 34548508457 scopus 로고    scopus 로고
    • Points to consider emerging from a mini-workshop on cardiac safety: Assessing torsades de pointes liability
    • 10.1016/j.vascn.2007.05.001
    • Bass A., Valentin J.-P., Fossa A.A., and Volders P.G.A. Points to consider emerging from a mini-workshop on cardiac safety: Assessing torsades de pointes liability. Journal of Pharmacological & Toxicological Methods 56 (2007) 91-94 10.1016/j.vascn.2007.05.001
    • (2007) Journal of Pharmacological & Toxicological Methods , vol.56 , pp. 91-94
    • Bass, A.1    Valentin, J.-P.2    Fossa, A.A.3    Volders, P.G.A.4
  • 8
    • 34548483458 scopus 로고    scopus 로고
    • ILSI-HESI cardiovascular safety subcommittee dataset: An analysis of the statistical properties of QT interval and rate-corrected QT interval (QTc)
    • 10.1016/j.vascn.2007.04.002
    • Chiang A.Y., Bass A.S., Cooper M.M., Engwall M.J., Menton R.G., and Thomas K. ILSI-HESI cardiovascular safety subcommittee dataset: An analysis of the statistical properties of QT interval and rate-corrected QT interval (QTc). Journal of Pharmacological & Toxicological Methods 56 (2007) 95-102 10.1016/j.vascn.2007.04.002
    • (2007) Journal of Pharmacological & Toxicological Methods , vol.56 , pp. 95-102
    • Chiang, A.Y.1    Bass, A.S.2    Cooper, M.M.3    Engwall, M.J.4    Menton, R.G.5    Thomas, K.6
  • 12
    • 34548515318 scopus 로고    scopus 로고
    • Pharmacological validation of a semi-automated in vitro hippocampal brain slice assay for assessment of seizure liability
    • 10.1016/j.vascn.2007.04.008
    • Easter A., Sharp T.H., Valentin J.-P., and Pollard C.E. Pharmacological validation of a semi-automated in vitro hippocampal brain slice assay for assessment of seizure liability. Journal of Pharmacological & Toxicological Methods 56 (2007) 223-233 10.1016/j.vascn.2007.04.008
    • (2007) Journal of Pharmacological & Toxicological Methods , vol.56 , pp. 223-233
    • Easter, A.1    Sharp, T.H.2    Valentin, J.-P.3    Pollard, C.E.4
  • 13
    • 0035854839 scopus 로고    scopus 로고
    • ICHS7A: Safety pharmacology studies for human pharmaceuticals
    • Federal Register. ICHS7A: Safety pharmacology studies for human pharmaceuticals. Federal Register 66 (2001) 36791-36792
    • (2001) Federal Register , vol.66 , pp. 36791-36792
    • Federal Register1
  • 14
    • 2542499263 scopus 로고    scopus 로고
    • ICHS7B: Safety pharmacology studies for assessing the potential for delayed ventricular repolarisation (QT interval prolongation) by human pharmaceuticals
    • Federal Register. ICHS7B: Safety pharmacology studies for assessing the potential for delayed ventricular repolarisation (QT interval prolongation) by human pharmaceuticals. Federal Register 67 (2002) 40950-40951
    • (2002) Federal Register , vol.67 , pp. 40950-40951
    • Federal Register1
  • 16
    • 34548480951 scopus 로고    scopus 로고
    • Suitability of commonly used excipients for electrophysiological in-vitro safety assessment of effects on hERG potassium current and on rabbit Purkinje fiber action potential
    • 10.1016/j.vascn.2007.04.004
    • Himmel H.M. Suitability of commonly used excipients for electrophysiological in-vitro safety assessment of effects on hERG potassium current and on rabbit Purkinje fiber action potential. Journal of Pharmacological & Toxicological Methods 56 (2007) 145-158 10.1016/j.vascn.2007.04.004
    • (2007) Journal of Pharmacological & Toxicological Methods , vol.56 , pp. 145-158
    • Himmel, H.M.1
  • 17
    • 33644786245 scopus 로고    scopus 로고
    • Thorough QT/QTc not so thorough: removes torsadogenic predictors from the T-wave, incriminates safe drugs, and misses profibrillatory drugs
    • Hondeghem. Thorough QT/QTc not so thorough: removes torsadogenic predictors from the T-wave, incriminates safe drugs, and misses profibrillatory drugs. Journal of Cardiovascular Electrophysiology 17 (2006) 337-340
    • (2006) Journal of Cardiovascular Electrophysiology , vol.17 , pp. 337-340
    • Hondeghem1
  • 19
    • 34548490989 scopus 로고    scopus 로고
    • Towards automation of a valuable preclinical cardiac safety pharmacology assay: Evaluation of the effects of cardiac ion channel blockers on cardiac repolarisation in vitro
    • 10.1016/j.vascn.2007.03.008
    • Lightbown I.D., Johnson M., Davis A., Leaney J., and Leishman D.J. Towards automation of a valuable preclinical cardiac safety pharmacology assay: Evaluation of the effects of cardiac ion channel blockers on cardiac repolarisation in vitro. Journal of Pharmacological & Toxicological Methods 56 (2007) 194-202 10.1016/j.vascn.2007.03.008
    • (2007) Journal of Pharmacological & Toxicological Methods , vol.56 , pp. 194-202
    • Lightbown, I.D.1    Johnson, M.2    Davis, A.3    Leaney, J.4    Leishman, D.J.5
  • 20
    • 34548523478 scopus 로고    scopus 로고
    • The value added by measuring myocardial contractility 'in vivo' in safety pharmacological profiling of drug candidates
    • 10.1016/j.vascn.2007.03.004
    • Markert M., Klumpp A., Trautmann T., Mayer K., Stubhan M., and Guth B. The value added by measuring myocardial contractility 'in vivo' in safety pharmacological profiling of drug candidates. Journal of Pharmacological & Toxicological Methods 56 (2007) 203-211 10.1016/j.vascn.2007.03.004
    • (2007) Journal of Pharmacological & Toxicological Methods , vol.56 , pp. 203-211
    • Markert, M.1    Klumpp, A.2    Trautmann, T.3    Mayer, K.4    Stubhan, M.5    Guth, B.6
  • 22
    • 21344463329 scopus 로고    scopus 로고
    • Refining detection of drug-induced proarrhythmia: QT interval and TRIaD
    • Shah R.R., and Hondeghem L.M. Refining detection of drug-induced proarrhythmia: QT interval and TRIaD. Heart Rhythm 2 (2005) 758-772
    • (2005) Heart Rhythm , vol.2 , pp. 758-772
    • Shah, R.R.1    Hondeghem, L.M.2
  • 23
    • 34548513789 scopus 로고    scopus 로고
    • Evaluation of blood flow parameters in addition to blood pressure and electrocardiogram in the conscious telemetered beagle dog
    • 10.1016/j.vascn.2007.04.003
    • Taylor G.L., Patel B., and Sullivan A.T. Evaluation of blood flow parameters in addition to blood pressure and electrocardiogram in the conscious telemetered beagle dog. Journal of Pharmacological & Toxicological Methods 56 (2007) 212-217 10.1016/j.vascn.2007.04.003
    • (2007) Journal of Pharmacological & Toxicological Methods , vol.56 , pp. 212-217
    • Taylor, G.L.1    Patel, B.2    Sullivan, A.T.3
  • 24
    • 34548492056 scopus 로고    scopus 로고
    • Comparison of guinea-pig ventricular myocytes and dog Purkinje fibres for in vitro assessment of drug-induced delayed repolarization
    • 10.1016/j.vascn.2007.04.005
    • Terrar D.A., Wilson C.M., Graham S.G., Bryant S.M., and Heath B.M. Comparison of guinea-pig ventricular myocytes and dog Purkinje fibres for in vitro assessment of drug-induced delayed repolarization. Journal of Pharmacological & Toxicological Methods 56 (2007) 171-185 10.1016/j.vascn.2007.04.005
    • (2007) Journal of Pharmacological & Toxicological Methods , vol.56 , pp. 171-185
    • Terrar, D.A.1    Wilson, C.M.2    Graham, S.G.3    Bryant, S.M.4    Heath, B.M.5
  • 25
    • 34548499342 scopus 로고    scopus 로고
    • A canine model used to simultaneously assess potential neurobehavioural and cardiovascular effects of candidate drugs
    • 10.1016/j.vascn.2007.03.005
    • Tontodonati M., Fasdelli N., Moscardo E., Giarola A., and Dorigatti R. A canine model used to simultaneously assess potential neurobehavioural and cardiovascular effects of candidate drugs. Journal of Pharmacological & Toxicological Methods 56 (2007) 265-275 10.1016/j.vascn.2007.03.005
    • (2007) Journal of Pharmacological & Toxicological Methods , vol.56 , pp. 265-275
    • Tontodonati, M.1    Fasdelli, N.2    Moscardo, E.3    Giarola, A.4    Dorigatti, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.