Effects of Fusarium toxins on growth, humoral immune response and internal organs in weaner pigs, and the efficacy of apple pomace as an antidote

Journal of Animal Physiology and Animal Nutrition

Volumn 91, Issue 9-10, 2007, Pages 432-438

  Gutzwiller, A ^a   Czegledi L ^a   Stoll, P ^a   Bruckner, L ^b  

^a Swiss Fed Res Stn for Anim Prod   (Switzerland)

^b INSTITUTE OF VIROLOGY AND IMMUNOLOGY   (Switzerland)

Author keywords

Antidote; Apple pomace; Deoxynivalenol; Growth; Immune response; Pig

Indexed keywords

TRICHOTHECENE DERIVATIVE; VOMITOXIN; ZEARALENONE;

ANIMAL; ANIMAL FOOD; ANTIBODY PRODUCTION; APPLE; ARTICLE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; EATING; FEMALE; FOOD CONTAMINATION; FUSARIUM; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; MALE; METABOLISM; NEWBORN; ORGAN SIZE; RANDOMIZATION; SWINE; TREATMENT OUTCOME;

ANIMAL FEED; ANIMAL NUTRITION PHYSIOLOGY; ANIMALS; ANIMALS, NEWBORN; ANTIBODY FORMATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; FEMALE; FOOD CONTAMINATION; FUSARIUM; MALE; MALUS; ORGAN SIZE; RANDOM ALLOCATION; SWINE; TREATMENT OUTCOME; TRICHOTHECENES; ZEARALENONE;

ANIMALIA; FUSARIUM; MALUS X DOMESTICA; PARVOVIRUS; SUIDAE; TRITICUM AESTIVUM;

EID: 34548539759     PISSN: 09312439     EISSN: 14390396     Source Type: Journal    
DOI: 10.1111/j.1439-0396.2006.00672.x     Document Type: Article

References (29)

1. Agroscope Liebefeld-Posieux (ALP), 2004 : Fütterungsempfehlungen und Nährwerttabellen für Schweine. 3. Aufl. LmZ-Verlag Zollikofen, Switzerland.
2. Bergsjo, B. Langseth, W. Nafstad, I. Jansen, J. H. Larsen, H. J., 1993 : The effects of naturally deoxynivalenol-contaminated oats on the clinical condition, blood parameters, performance and carcass composition of growing pigs. Veterinary Research Communications 17, 283 294.
3. Blackwood, A. D. Salter, J. Dettmar, P. W. Chaplin, M. F., 2000 : Dietary fibre, physicochemical properties and their relation to health. The Journal of the Royal Society for the Promotion of Health 120, 242 247.
4. Carson, M. S. Smith, T. K., 1983 : Effect of feeding alfalfa and refined plant fibers on the toxicity and metabolism of T-2 toxin in rats. Journal of Nutrition 113, 304 313.
5. Chavez, E. R., 1984 : Vomitoxin-contaminated wheat in pig diets: pregnant and lactating gilts and weaners. Canadian Journal of Animal Science 64, 717 723.
6. Dänicke, S. Valenta, H. Döll, S. Ganter, M. Flachowsky, G., 2004 : On the effectiveness of a detoxifying agent in preventing fusariotoxicosis in fattening pigs. Animal Feed Science and Technology 114, 141 157.
7. Dersjant-Li, Y. Verstegen, M. W. Gerrits, W. J., 2003 : The impact of low concentrations of aflatoxin, deoxynivalenol or fumonisin in diets on growing pigs and poultry. Nutrition Research Reviews 16, 223 239.
8. Dillenburger, T. Lauber, U. Klobasa, F. Drochner, W., 2001 : Deoxynivalenol in pigs: an exclusive effect on the appetite? Mycotoxin Research 17, 58 61.
9. Döll, S. Dänicke, S., 2004 : In vivo detoxification of Fusarium toxins. Archives of Animal Nutrition 58, 419 441.
10. Döll, S. Dänicke, S. Schnurrbusch, U. Flachowsky, G., 2002 : Effects of different concentrations of deoxynivalenol and zearalenone in diets for prebubertal female pigs - preliminary results. Proceedings of the Society of Nutritional Physiology 11, 98.
11. Döll, S. Dänicke, S. Ueberschaer, K.-H. Valenta, H. Schnurrbusch, U. Ganter, C. Klobasa, F. Flachowsky, G., 2003 : Effects of graded levels of Fusarium toxin contaminated maize in diets for female weaned piglets. Archives of Animal Nutrition 57, 311 334.
12. Döll, S. Dänicke, S. Valenta, H. Flachowsky, G., 2004 : In vitro studies on the evaluation of mycotoxin detoxifying agents for their efficacy on deoxynivalenol and zearalenone. Archives of Animal Nutrition 58, 311 324.
13. Dunjic, B. S. Svensson, I. Axelson, J. Adlercreutz, P. Ar'Rajab, A. Larsson, A. Bengmark, S., 1993 : Green banana protection of gastric mucosa against experimentally induced injuries in rats. A multicomponent mechanism? Scandinavian Journal of Gastroenterology 28, 894 898.
14. EG-Kommission, 2006 : Empfehlung der Kommission vom 17. August 2006 betreffend das Vorhandensein von Deoxynivalenol, Zearalenon, Ochratoxin A, T-2- und HT-2-Toxin sowie von Fumonisinen in zur Verfütterung an Tiere bestimmten Erzeugnissen (2006/576/EG). Amtsblatt der Europäischen Union 49, 23.
15. Ferrucci, F. Zucca, E. Croci, C. Di Fabio, V. Ferro, E., 2003 : Treatment of gastric ulceration in 10 standardbred racehorses with a pectin-lecithin complex. The Veterinary Record 152, 679 681.
16. Lauber, U. Dillenburger, T. Drochner, W., 2001 : Distinct effects of equal levels of Fusarium toxins (deoxynivalenol) in growing pigs. Possible reasons. Mycotoxin Research 17, 53 57.
17. Low, A. G., 1989 : Secretory responses of the pig gut to non-starch polysaccharides. Animal Feed Science and Technology 23, 55 65.
18. Maresca, M. Mahfoud, R. Garmy, N. Fantini, J., 2002 : The mycotoxin deoxynivalenol affects nutrient absorption in human intestinal epithelial cells. Journal of Nutrition 132, 2723 2731.
19. Naumann, C. Bassler, R., 1997 : Die chemische Untersuchung von Futtermitteln. VDLUFA-Verlag, Darmstadt.
20. Overnes, G. Matre, T. Sivertsen, T. Larsen, H. J. Langseth, W. Reitan, L. Jansen, J. H., 1997 : Effects of diets with graded levels of naturally deoxynivalenol-contaminated oats on immune response in growing pigs. Zentralblatt für Veterinärmedizin A 44, 539 550.
21. Prelusky, D. B., 1993 : The effect of low-level deoxynivalenol on neurotransmitter levels measured in pig cerebral spinal fluid. Journal of Environmental Science and Health. Part B, Pesticides, Food Contaminants, and Agricultural Wastes 28, 731 761.
22. Robbana-Barnat, S. Lafarge-Frayssinet, C. Cohen, H. Neish, G. A. Frayssinet, C., 1988 : Immunosuppressive properties of deoxynivalenol. Toxicology 48, 155 166.
23. Rotter, B. A. Thompson, B. K. Lessard, M. Trenholm, H. L. Tryphonas, H., 1994 : Influence of low-level exposure to Fusarium mycotoxins on selected immunological and haematological parameters in young swine. Fundamental and Applied Toxicology 23, 117 124.
24. Swamy, H. V. Smith, T. K. MacDonald, E. J. Boermans, H. J. Squires, E. J., 2002 : Effects of feeding a blend of grains naturally contaminated with Fusarium mycotoxins on swine performance, brain regional neurochemistry, and serum chemistry, and the efficacy of a polymeric glucomannan mycotoxin adsorbent. Journal of Animal Science 80, 3257 3267.
25. Swamy, H. V. Smith, T. K. MacDonald, E. J. Karrow, N. A. Woodward, B. Boermans, H. J., 2003 : Effects of feeding a blend of grains naturally contaminated with Fusarium mycotoxins on growth and immunological measurements of starter pigs, and the efficacy of a polymeric glucomannan mycotoxin adsorbent. Journal of Animal Science 81, 2792 2803.
26. Tiemann, U. Brüssow, K.-P. Jonas, L. Pöhland, R. Schneider, F. Dänicke, S., 2006 : Effects of diets with cereal grains contaminated by graded levels of two Fusarium toxins on selected immunological and histological measurements in the spleen of gilts. Journal of Animal Science 84, 236 245.
27. Trenholm, H. L. Foster, B. C. Charmley, L. L. Thompson, B. K. Hartin, K. E. Coppock, R. W. Albassam, M. A., 1994 : Effects of feeding diets containing Fusarium (naturally) contaminated wheat or pure deoxynivalenol (DON) in growing pigs. Canadian Journal of Animal Science 74, 361 369.
28. Tryphonas, H. Iverson, F. So, Y. Nera, E. A. McGuire, P. F. O'Grady, L. Clayson, D. B. Scott, P. M., 1986 : Effects of deoxynivalenol (vomitoxin) on the humoral and cellular immunity of mice. Toxicology Letters 30, 137 150.
29. Young, L. G. McGirr, L. Valli, V. E. Lumsden, J. H. Lun, A., 1983 : Vomitoxin in corn fed to young pigs. Journal of Animal Science 57, 655 664.