Human leukocyte antigen may predict outcome of primary recurrent spontaneous abortion treated with paternal lymphocyte alloimmunization therapy

American Journal of Reproductive Immunology

Volumn 58, Issue 4, 2007, Pages 383-387

  Kano, Takashi ^a   Mori, Takahide ^b,c   Furudono, Masako ^a   Ishikawa, Hironobu ^b   Watanabe, Hirohiko ^b   Kikkawa, Eri ^d   Warita, Takayuki ^d   Onizuka, Makoto ^d   Takahashi, Megumi ^e   Maeda, Yutaka ^f   Naruse, Taeko ^e   Inoko, Hidetoshi ^d   Kimura, Akinori ^e  

^a Medical Corporation Kano Clinic   (Japan)

^b Daigo Watanabe Hospital   (Japan)

^c Medical Academia for Reproductive Regeneration   (Japan)

^d TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^f FALCO Biosystems Ltd   (Japan)

Author keywords

Haplotype; HLA G; Paternal lymphocyte immunization; Recurrent spontaneous abortion

Indexed keywords

HLA A ANTIGEN; HLA ANTIGEN; HLA C ANTIGEN; HLA DR ANTIGEN; HLA E ANTIGEN; HLA G ANTIGEN;

ALLOIMMUNIZATION; ARTICLE; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; EXON; FEMALE; GENE FREQUENCY; HLA TYPING; HUMAN; HUMAN CELL; PATERNAL LYMPHOCYTE ALLOIMMUNIZATION; PREDICTION; PREGNANCY OUTCOME; PRIORITY JOURNAL; PROMOTER REGION; SENSITIVITY AND SPECIFICITY; SPONTANEOUS ABORTION; TREATMENT OUTCOME;

ABORTION, HABITUAL; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HLA-A ANTIGENS; HLA-B ANTIGENS; HLA-C ANTIGENS; HLA-DR ANTIGENS; HUMANS; LIVE BIRTH; LYMPHOCYTE TRANSFUSION; PATIENT SELECTION; POLYMORPHISM, GENETIC; PREGNANCY; TREATMENT OUTCOME;

EID: 34548537264     PISSN: 10467408     EISSN: 16000897     Source Type: Journal    
DOI: 10.1111/j.1600-0897.2007.00517.x     Document Type: Article

References (20)

1. Pandy MK, Rani R, Agrawal S: An update in recurrent spontaneous abortion. Arch Gynecol Obstet 2005; 272: 95-108.
2. Pandy MK, Thakur S, Agrawal S: Lymphocyte immunotherapy and its probable mechanism in the maintenance of pregnancy in women with recurrent spontaneous abortion. Arch Gynecol Obstet 2004; 269: 161-172.
3. Chaouat G: Should we re-examine the status of lymphocyte alloimmunization therapy for recurrent spontaneous abortion? Am J Reprod Immunol 2003; 50: 433-438.
4. Choudhury SR, Knapp LA: Human reproductive failure II: Immunogenetic and interacting factors. Hum Reprod Update 2001; 7: 135-169.
5. Laird SM, Tuckerman EM, Cork BA, Linjawi S, Blakemore AIF, Li TC: A review of immune cells and molecules in women with recurrent miscarriage. Hum Reprod Update 2003; 9: 163-174.
6. McCluskey J, Peh CA: The human leukocyte antigens and clinical medicine: and overview. Rev Immunogenet 1999; 1: 3-20.
7. Christiansen OB, Ring M, Rosgaard A, Grunnet N, Gluud C: Association between HLA-DR1 and -DR3 antigens and unexpected repeated miscarriage. Hum Reprod Update 1999; 5: 249-255.
8. Takakuwa K, Adachi H, Hataya I, Ishii K, Tamura M, Tanaka K: Molecular genetic studies of HLA-DRB1 alleles in patients with unexplained recurrent abortion in the Japanese population. Hum Reprod 2003; 18: 728-733.
9. Hunt JS, Petroff MG, McIntire RH, Ober C: HLA-G and immune tolerance in pregnancy. FASEB J 2005; 19: 681-693.
10. Pfeiffer KA, Fimmer R, Engels G, van der Ven H, van der Ven K: The HLA-G genotype is potentially associated with idiopathic recurrent spontaneous abortion. Mol Hum Reprod 2001; 7: 373-378.
11. Aldrich CL, Stephenson MD, Karrison T, Odem RR, Branch D, Scott JR, Schreiber JR, Ober C: HLA-G genotypes and pregnancy outcome in couples with unexplained recurrent miscarriage. Mol Hum Reprod 2001; 7: 1167-1172.
12. Hviid TV, Hylenius S, Hoegh AM, Kruse C, Christiansen OB: HLA-G polymorphisms in couples with recurrent spontaneous abortions. Tissue Antigens 2002; 60: 122-132.
13. Ober C, Aldrich CL, Chervoneva I, Billstrand C, Rahimov F, Gray HI, Hyslop T: Variation in the promoter region influences miscarriage rates. Am J Hum Genet 2003; 72: 1425-1435.
14. Hviid TVF, Hylenius S, Lindhard A, Christiansen OE: Association between human leukocyte antigen-G genotype and success of in vitro fertilization and pregnancy outcome. Tissue Antigens 2004; 64: 66-69.
15. Tripathi P, Abbas A, Naik S, Agrawal S: Role of 14-bp deletion in the HLA-G gene in the maintenance of pregnancy. Tissue Antigens 2004; 64: 706-710.
16. Yan WH, Lin A, Chen XJ, Dai MZ, Gan LH, Zhou MY, Zhu M, Shi WW, Liu JM: Association of the maternal 14-bp insertion polymorphism in the HLA-G gene in women with recurrent spontaneous abortions. Tissue Antigens 2006; 68: 521-523.
17. RozemullerAEH, Tilanus MG: Bioinformatics: analysis of HLA sequencing data. Rev Immunogenet 2000; 2: 492-517.
18. Imanishi T, Akaza T, Kimura A, Tokunaga K, Gojobori T: Reference tables: allele frequencies and haplotype frequencies for HLA and complement loci in various ethnic groups. In HLA1991 vol. 1, K Tsuji, M Aizawa, T Sasazuki (eds). Oxford, Oxford University Press, 1992, pp 1065-1220.
19. Shibata H, Yasunami M, Obuchi N, Takahashi M, Kobayashi Y, Numano F, Kimura A: Direct determination of SNP haplotype of NFKBIL1 promoter polymorphism by DNA conformation analysis and its application to association study of chronic inflammatory diseases. Hum Immunol 2006; 67: 363-373.
20. Wilczynski JR: Immunological analogy between allograft rejection, recurrent abortion and pre-eclampsia-the same basic mechanism? Hum Immunol 2006; 67: 492-511.