Acute generalized exanthematous pustulosis from dalteparin

Journal of the American Academy of Dermatology

Volumn 57, Issue 4, 2007, Pages 718-721

  Komericki, Peter ^a   Grims, Robert ^a   Kränke, Birger ^a   Aberer, Werner ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; CERTOPARIN; DALTEPARIN; DANAPAROID; ENOXAPARIN; FONDAPARINUX; HEPARIN DERIVATIVE; LOW MOLECULAR WEIGHT HEPARIN; NADROPARIN; PENTOSAN POLYSULFATE; REVIPARIN;

ADULT; ALLERGY TEST; ARTICLE; CASE REPORT; DELAYED HYPERSENSITIVITY; DRUG ERUPTION; FEMALE; HUMAN; INJECTION SITE ERYTHEMA; INJECTION SITE PRURITUS; INJECTION SITE REACTION; PRIORITY JOURNAL; PROVOCATION TEST; PUSTULE; PUSTULOSIS; RASH; SUPERFICIAL THROMBOPHLEBITIS; VENOUS THROMBOEMBOLISM;

ACUTE DISEASE; ANTICOAGULANTS; DALTEPARIN; DRUG ERUPTIONS; EXANTHEMA; FEMALE; HUMANS; INJECTIONS; MIDDLE AGED; SKIN DISEASES, PAPULOSQUAMOUS; SKIN TESTS; THROMBOPHLEBITIS;

EID: 34548534555     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2007.05.025     Document Type: Article

References (21)

1. Ginsberg J.S. Management of venous thromboembolism. N Engl J Med 335 (1996) 1816-1818
2. Green D., Hirsh J., Heit J., Prins M., Davidson B., and Lensing A.W. Low molecular weight heparin: a critical analysis of clinical trials. Pharmacol Rev 46 (1994) 89-109
3. Nurmohamed M.T., ten Cate H., and ten Cate J.W. Low molecular weight heparin(oid)s: clinical investigations and practical recommendations. Drugs 53 (1997) 736-751
4. Weitz J.I. Low molecular weight heparins. [erratum appears in N Engl J Med 1997;337:1567]. N Engl J Med 337 (1997) 688-698
5. Grassegger A., Fritsch P., and Reider N. Delayed-type hypersensitivity and cross-reactivity to heparins and danaparoid: a prospective study. Dermatol Surg 27 (2001) 47-52
6. Bircher A.J., Harr T., Hohenstein L., and Tsakiris D.A. Hypersensitivity reactions to anticoagulant drugs: diagnosis and management options. Allergy 61 (2006) 1432-1440
7. Szolar-Platzer C., Aberer W., and Kränke B. Delayed-type skin reaction to the heparin-alternative danaparoid. J Am Acad Dermatol 43 (2000) 920-922
8. Poza-Guedes P., Gonzalez-Perez R., and Canto G. Different pattern of cross-reactivity in non-immediate hypersensitivity to heparins: from localized to systemic reactions. Contact Dermatitis 47 (2003) 244-245
9. Beltraminelli H.S., Lerch M., Arnold A., Bircher A.J., and Häusermann P. Acute generalized exanthematous pustulosis induced by the antifungal terbinafine: case report and review of the literature. Br J Dermatol 152 (2005) 780-783
10. Arroyo M.P., Heller P., and Pomeranz M.K. Generalized pustules in a healthy woman. J Drugs Dermatol 1 (2002) 63-65
11. Litt J.Z. Drug eruption reference manual. 12th ed. (2006), Taylor and Francis, London and New York
12. Roujeau J.C., Bioulac-Sage P., Bourseau C., Guillaume J.C., Bernard P., Lok C., et al. Acute generalized exanthematous pustulosis: analysis of 63 cases. Arch Dermatol 127 (1991) 1333-1338
13. Sidoroff A., Halevy S., Bavinck J.N.B., Vaillant L., and Roujeau J.C. Acute generalized exanthematous pustulosis (AGEP)-a clinical reaction pattern. J Cutan Pathol 28 (2001) 113-119
14. Bircher A.J., Flückinger R., and Buchner S.A. Eczematous infiltrated plaques to subcutaneous heparin: a type IV allergic reaction. Br J Dermatol 123 (1990) 507-514
15. Koch P., Munssinger T., Rupp-John C., and Uhl K. Delayed-type hypersensitivity skin reactions caused by subcutaneous unfractioned and low-molecular-weight heparins: tolerance of a new recombinant hirudin. J Am Acad Dermatol 42 (2000) 612-619
16. Britschgi M., Steiner U.C., Schmid S., Depta J.P., Senti G., Bircher A., et al. T-cell involvement in drug-induced acute generalized exanthematous pustulosis. J Clin Invest 107 (2001) 1433-1441
17. Wolkenstein P., Chosidow O., Flechet M.L., Robbiola O., Paul M., Dume L., et al. Patch testing in severe cutaneous adverse drug reactions, including Stevens-Johnson-syndrome and toxic epidermal necrolysis. Contact Dermatitis 35 (1996) 234-236
18. Pichler W.J. Delayed drug hypersensitivity reactions. Ann Intern Med 139 (2003) 683-693
19. Hunzelmann N., Gold H., and Scharffetter-Kochanek K. Concomitant sensitization to high and low molecular-weight heparins, heparinoid and pentosanpolyphosphate. Contact Dermatitis 39 (1998) 88-89
20. Jappe U., Juschka U., Kuner N., Hausen B.M., and Krohn K. Fondaparinux: a suitable alternative in cases of delayed-type allergy to heparins and heparinoids? A study of 7 cases. Contact Dermatitis 51 (2004) 67-72
21. Ludwig R.J., Schindewolf M., Alban S., Kaufmann R., Lindhoff-Last E., and Boehncke W.-H. Molecular weight determines the frequency of delayed type hypersensitivity reactions to heparins and synthetic oligosaccharides. Thromb Haemost 94 (2005) 1265-1269