Mass spectrometric analysis of oxygenations in aromatization of androst-4-ene-3,6,17-trione, a suicide substrate of aromatase, by placental microsomes. Isotope effect and stereochemistry

Journal of Steroid Biochemistry and Molecular Biology

Volumn 107, Issue 3-5, 2007, Pages 220-227

  Numazawa, Mitsuteru ^a   Takahashi, Madoka ^a   Nagaoka, Masao ^a   Handa, Wakako ^a   Yamashita, Kouwa ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

19 Oxygenation; 6 Oxoandrostenedione; Aromatase; Deuterium isotope effect; Mass spectrometry; Stereochemistry; Suicide substrate

Indexed keywords

19 HYDROXY 6 OXOSTEROID; ADRENOSTERONE; ALCOHOL; ANDROST 4 ENE 3,6,7 TRIONE; AROMATASE; DEUTERIUM; ESTRONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

AROMATIZATION; ARTICLE; CATALYSIS; CONTROLLED STUDY; GAS CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROXYLATION; INCUBATION TIME; ISOMERISM; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROSOME; OXYGENATION; STEREOCHEMISTRY;

ANDROSTENES; FEMALE; HUMANS; ISOTOPES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICROSOMES; OXYGEN; PLACENTA; STEREOISOMERISM;

EID: 34548508996     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2007.03.041     Document Type: Article

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