Differential gene expression induction by TRAIL in B chronic lymphocytic leukemia (B-CLL) cells showing high versus low levels of Zap-70

Journal of Cellular Physiology

Volumn 213, Issue 1, 2007, Pages 229-236

  Secchiero, Paola ^a   Di Iasio, Maria Grazia ^a   Gonelli, Arianna ^a   Barbarotto, Elisa ^a   Melloni, Elisabetta ^b   Tiribelli, Mario ^c   Chiaruttini, Cristina ^b   Zauli, Giorgio ^b  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c UNIVERSITY HOSPITAL OF UDINE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CASPASE; CELL CYCLE PROTEIN; CHLORAMBUCIL; CYCLIN DEPENDENT KINASE; CYCLOOXYGENASE 2; DEATH RECEPTOR; FAS ANTIGEN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 8; MESSENGER RNA; PROTEIN BCL 2; PROTEIN KINASE ZAP 70; PROTEIN MDM2; PROTEIN P53; RECOMBINANT PROTEIN; SURVIVIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL SURVIVAL; CELL VIABILITY; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; DNA DAMAGE; DNA MICROARRAY; DNA REPLICATION; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HEAT SHOCK; HUMAN; HUMAN CELL; INFLAMMATION; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, ALKYLATING; CHLORAMBUCIL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUKEMIA, B-CELL, CHRONIC; RECOMBINANT PROTEINS; RNA, MESSENGER; RNA, NEOPLASM; TNF-RELATED APOPTOSIS-INDUCING LIGAND; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 34548496480     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21116     Document Type: Article

References (33)

1. Abdollahi T, Robertson NM, Abdollahi A, Liwack G. 2003. Identification of interleukin 8 as an inhibitor of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in the ovarian carcinoma cell line OVCAR3. Cancer Res 63:4521-4526.
2. Billard C, Kern C, Tang R, Ajchenbaum-Cymbalista F, Kolb JP. 2003. Flavopiridol downregulates the expression of both the inducible NO synthase and p27(kip1) in malignant cells from B-cell chronic lymphocytic leukemia. Leukemia 17:2435-2443.
3. Choi C, Lutsch O, Park J, Zhou T, Seol DW, Benveniste EN. 2002. Tumor necrosis factor-related apoptosis-inducing ligand induces caspase-dependent interleukin-8 expression and apoptosis in human astroglioma cells. Mol Cell Biol 22:724-736.
4. Decker T, Hipp S, Ringshausen I, Bogner C, Oelsner M, Schneller F, Peschel C. 2003. Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin. Blood 101:278-285.
5. Di Celle PF, Mariani S, Riera L, Stacchini A, Reato G, Carbone A, Foa R. 1996. Interleukin-8 induces the accumulation of B-cell chronic lymphocytic leukemia cells by prolonged survival in an autocrine fashion. Blood 87:4382-4389.
6. Gobessi S, Laurenti L, Longo PG, Sica S, Leone G, Efremov DG. 2006. Prepublished online October 12, ZAP-70 enhances B-cell receptor signaling in spite of absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B-cells. Blood First Edition Paper. 10.1182/blood-2006- 03-011759.
7. Granziero L, Ghia P, Circosta P, Gottardi D, Strola G, Geuna M, Montagna L, Piccoli P, Chilosi M, Caligaris-Cappio F. 2001. Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia. Blood 97:2777-2783.
8. Janssen EM, Droin NM, Lemmens EE, Pinkoski MJ, Bensinger SJ, Ehst BD, Griffith TS, Green DR, Schoenberger SP. 2005. CD4 T-cell help controls CD8 T-cell memory via TRAIL-mediated activation-induced cell death. Nature 434:88-91.
9. Johnston JB, Kabore AF, Strutinsky J, Hu X, Paul JT, Kropp DM, Kuschak B, Begleiter A, Gibson SB. 2003. Role of the TRAIL/APO2-L death receptors in chlorambucil- and fludarabine-induced apoptosis in chronic lymphocytic leukemia. Oncogene 22:8356-8369.
10. Kanaoka S, Takai T, Yoshida K. 2007. Cyclooxygenase-2 and tumor biology. Adv Clin Chem 43:59-78.
11. MacFarlane M, Harper N, Snowden RT, Dyer MJ, Barnett GA, Pringle JH, Cohen GM. 2002. Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia. Oncogene 21:6809-6818.
12. MacFarlane M, Inoue S, Kohlhaas SL, Majid A, Harper N, Kennedy DBJ, Dyer MJS, Cohen GM. 2005. Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAIL-R1. Cell Death Differ 12:773-782.
13. Messmer BT, Messmer D, Allen SL, Kolitz JE, Kudalkar P, Cesar D, Murphy EJ, Koduru P, Ferrarini M, Zupo S, Cutrona G, Damle RN, Wasil T, Rai KR, Hellerstein MK, Chiorazzi N. 2005. In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. J Clin Invest 115:755-764.
14. Molica S, Vitelli G, Levato D, Levato L, Dattilo A, Gandolfo GM. 1999. Clinico-biological implications of increased serum levels of interleukin-8 in B-cell chronic lymphocytic leukemia. Haematologica 84:208-211.
15. Olsson A, Diaz T, Aguilar-Santelises M, Osterborg A, Celsing F, Jondal M, Osorio LM. 2001. Sensitization to TRAIL-induced apoptosis and modulation of FLICE inhibitory protein in B chronic lymphocytic leukemia by actinomycin D. Leukemia 15:1868-1877.
16. Reed JC, Kitada S, Kim Y, Byrd J. 2002. Modulating apoptosis pathways in low grade B-cell malignancies using biological response modifiers. Semin Oncol 29:10-24.
17. Richardson SJ, Matthews C, Catherwood MA, Alexander HD, Carey BS, Farrugia J, Gardiner A, Mould S, Oscier D, Copplestone JA, Prentice AG. 2006. ZAP-70 expression is associated with enhanced ability to respond to migratory and survival signals in B-cell chronic lymphocytic leukemia (B-CLL). Blood 107:3584-3592.
18. Rosenwald A, Chuang EY, Davis RE, Wiestner A, Alizadeh AA, Arthur DC, Mitchell JB, Marti GE, Fowler DH, Wilson WH, Staudt LM. 2004. Fludarabine treatment of patients with chronic lymphocytic leukemia induces a p53-dependent gene expression response. Blood 104:1428-1434.
19. Rozman C, Montserrat E. 1995. Chronic lymphocytic leukemia. N Engl J Med 333:1052-1057.
20. Ryan EP, Pollock SJ, Kaur K, Felgar RE, Bernstein SH, Chiorazzi N, Phipps RP. 2006. Constitutive and activation-inducible cyclooxygenase-2 expression enhances survival of chronic lymphocytic leukemia B cells. Clin Immunol 120:76-90.
21. Secchiero P, Melloni E, Heikinheimo M, Mannisto S, Di Pietro R, Iacone A, Zauli G. 2004. TRAIL regulates normal erythroid maturation through an ERK-dependent pathway. Blood 103:517-522.
22. Secchiero P, Tiribelli M, Barbarotto E, Celeghini C, Michelutti A, Masolini P, Fanin R, Zauli G. 2005a. Aberrant expression of TRAIL in B chronic lymphocytic leukemia (B-CLL) cells. J Cell Physiol 205:246-252.
23. Secchiero P, Corallini F, di Iasio MG, Gonelli A, Barbarotto E, Zauli G. 2005b. TRAIL counteracts the proadhesive activity of inflammatory cytokines in endothelial cells by down-modulating CCL8 and CXCL10 chemokine expression and release. Blood 105:3413-3419.
24. Secchiero P, Barbarotto E, Gonelli A, Tiribelli M, Zerbinati C, Celeghini C, Agostinelli C, Pileri SA, Zauli G. 2005c. Potential pathogenetic implications of cyclooxygenase-2 overexpression in B chronic lymphoid leukemia cells. Am J Pathol 167:1599-1607.
25. Secchiero P, Barbarotto E, Tiribelli M, Zerbinati C, di Iasio MG, Gonelli A, Cavazzini F, Campioni D, Fanin R, Cuneo A, Zauli G. 2006. Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL). Blood 107:4122-4129.
26. Stratowa C, Offler GL, Lichter P, Stilgenbauer S, Haberl P, Schweifer N, Ohner HD, Wilgenbus KK. 2001. cDNA microarray gene expression analysis of B-cell chronic lymphocytic leukemia proposes potential new prognostic markers involved in lymphocyte trafficking. Int J Cancer 91:474-480.
27. Sturm I, Bosanquet AG, Hermann S, Guner D, Dorken B, Daniel PT. 2003. Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy. Cell Death Differ 10:477-484.
28. Till KJ, Zuzel M, Cawley JC. 1999. The role of hyaluronan and interleukin 8 in the migration of chronic lymphocytic leukemia cells within lymphoreticular tissues. Cancer Res 59:4419-4426.
29. Zauli G, Secchiero P. 2006. The role of the TRAIL/TRAIL-receptors system in hematopoiesis and endothelial cell biology. Cytokine Growth Factor Rev 17:245-257.
30. Zauli G, Re MC, Visani G, Furlini G, Mazza P, Vignoli M, La Placa M. 1992. Evidence for an HIV-1 mediated supression of uninfected hematopoietic (CD34+) progenitor cells in vivo. J Inf Dis 166:710-716.
31. Zerafa N, Westwood JA, Cretney E, Mitchell S, Waring P, Iezzi M, Smyth MJ. 2005. TRAIL deficiency accelerates hematological malignancies. J Immunol 175:5586-5590.
32. Zhao H, Dugas N, Mathiot C, Delmer A, Dugas B, Sigaux F, Kolb JP. 1998. B-cell chronic lymphocytic leukemia cells express a functional inducible nitric oxide synthase displaying anti-apoptotic activity. Blood 92:1031-1043.
33. Zinzani PL. 2003. Traditional treatment approaches in B-cell non-Hodgkin's lymphoma. Leuk Lymphoma 44:S1-S4.