The role of biofilms in otolaryngologic infections: Update 2007

Current Opinion in Otolaryngology and Head and Neck Surgery

Volumn 15, Issue 5, 2007, Pages 347-351

  Post, J Christopher ^a,b,c   Hiller, N Luisa ^a   Nistico, Laura ^a   Stoodley, Paul ^a,c   Ehrlich, Garth D ^a,c  

^a ALLEGHENY SINGER RESEARCH INSTITUTE   (United States)

^b ALLEGHENY GENERAL HOSPITAL   (United States)

^c DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Adenoiditis; Biofilm; Cholesteatoma; Otitis media; Sinusitis; Tonsillitis

Indexed keywords

ANTIBIOTIC AGENT; CHEMOKINE; CYTOKINE; PROBIOTIC AGENT; TOBRAMYCIN;

ADENOIDECTOMY; ANTIBIOTIC RESISTANCE; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERIUM ISOLATE; BIOFILM; CHOLESTEATOMA; CHRONIC TONSILLITIS; CLINICAL OBSERVATION; COCHLEA PROSTHESIS; CONFOCAL LASER MICROSCOPY; DEVICE INFECTION; EAR INFECTION; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; MICROBIAL DIVERSITY; MIDDLE EAR EFFUSION; MIDDLE EAR MUCOSA; NONHUMAN; OTORRHEA; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RECURRENT DISEASE; REVIEW; RHINOSINUSITIS; SCANNING ELECTRON MICROSCOPY; SECRETORY OTITIS MEDIA; SINUSITIS; TONSILLITIS; TRACHEOTOMY;

ADENOIDS; ANTI-BACTERIAL AGENTS; BACTERIA; BIOFILMS; EQUIPMENT CONTAMINATION; HUMANS; OTITIS MEDIA; OTOLARYNGOLOGY; PROBIOTICS; RHINITIS; SINUSITIS; TONSIL;

EID: 34548493434     PISSN: 10689508     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOO.0b013e3282b97327     Document Type: Review

References (29)

1. Post JC, Stoodley P, Hall-Stoodley L, Ehrlich GD. The role of biofilms in otolaryngologic infections. Curr Opin Otolaryngol Head Neck Surg 2004; 12:185-190.
2. Borriello G, Werner E, Roe F, et al. Oxygen limitation contributes to antibiotic tolerance of Pseudomonas aeruginosa in biofilms. Antimicrob Agents Chemother 2004; 48:2659-2664.
3. Klausen M, Aaes-Jorgensen A, Molin S, Tolker-Nielsen T. Involvement of bacterial migration in the development of complex multicellular structures in Pseudomonas aeruginosa biofilms. Mol Microbiol 2003; 50:61-68.
4. Hall-Stoodley L, Hu FZ, Gieseke A, et al. Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media. JAMA 2006; 296:202-211. The first demonstration of middle-ear mucosal biofilms in children with chronic OME.
5. Claverys JP, Havarstein LS. Cannibalism and fratricide: mechanisms and raisons d'etre. Nat Rev Microbiol 2007; 5:219-229.
6. Prudhomme M, Attaiech L, Sanchez G, et al. Antibiotic stress induces genetic transformability in the human pathogen Streptococcus pneumoniae. Science 2006; 313:89-92.
7. Jurcisek JA, Bakaletz LO. Biofilms formed by nontypeable Haemophilus influenzae in vivo contain both double-stranded DNA and type IV pilin protein. J Bacteriol 2007; 189:3868-3875. The first demonstration of DNA in H. influenzae biofilms, suggesting a new target for antibiofilm agents.
8. Wang EW, Jung JY, Pashia ME, et al. Otopathogenic Pseudomonas aeruginosa strains as competent biofilm formers. Arch Otolaryngol Head Neck Surg 2005; 131:983-989.
9. Starner TD, Zhang N, Kim G, et al. Haemophilus influenzae forms biofilms on airway epithelia: implications in cystic fibrosis. Am J Respir Crit Care Med 2006; 174:213-220.
10. Perloff JR, Palmer JN. Evidence of bacterial biofilms in a rabbit model of sinusitis. Am J Rhinol 2005; 19:1-6.
11. Perloff JR, Palmer JN. Evidence of bacterial biofilms on frontal recess stents in patients with chronic rhinosinusitis. Am J Rhinol 2004; 18:377-380.
12. Cryer J, Schipor I, Perloff JR, Palmer JN. Evidence of bacterial biofilms in human chronic sinusitis. ORL J Otorhinolaryngol Relat Spec 2004; 66:155-158.
13. Sanclement JA, Webster P, Thomas J, Ramadan HH. Bacterial biofilms in surgical specimens of patients with chronic rhinosinusitis. Laryngoscope 2005; 115:578-582.
14. Ramadan HH, Sanclement JA, Thomas JG. Chronic rhinosinusitis and bio-films. Otolaryngol Head Neck Surg 2005; 132:414-417.
15. Sanderson AR, Leid JG, Hunsaker D. Bacterial biofilms on the sinus mucosa of human subjects with chronic rhinosinusitis. Laryngoscope 2006; 116:1121-1126. A demonstration using state-of-the-art visualization techniques that biofilms are associated with CRS.
16. Bendouah Z, Barbeau J, Hamad WA, Desrosiers M. Biofilm formation by Staphylococcus aureus and Pseudomonas aeruginosa is associated with an unfavorable evolution after surgery for chronic sinusitis and nasal polyposis. Otolaryngol Head Neck Surg 2006; 134:991-996. Further evidence that biofilms are involved in CRS.
17. Coticchia J, Zuliani G, Coleman C, et al. Biofilm surface area in the pediatric nasopharynx: chronic rhinosinusitis vs obstructive sleep apnea. Arch Otolaryngol Head Neck Surg 2007; 133:110-114. Evidence that the efficacy of adenoidectomy in the control of otitis media or sinusitis is related to the removal of an infectious burden.
18. Chole RA, Faddis BT. Anatomical evidence of microbial biofilms in tonsillar tissues: a possible mechanism to explain chronicity. Arch Otolaryngol Head Neck Surg 2003; 129:634-636.
19. Kania RE, Lamers GE, Vonk MJ, et al. Demonstration of bacterial cells and glycocalyx in biofilms on human tonsils. Arch Otolaryngol Head Neck Surg 2007; 133:115-121.
20. Galli J, Ardito F, Calo L, et al. Recurrent upper airway infections and bacterial biofilms. J Laryngol Otol 2007; 121:341-344. A nice demonstration that biofilms are present in a variety of refactory upper-airway infections.
21. Baldassarri L, Creti R, Recchia S, et al. Therapeutic failures of antibiotics used to treat macrolide-susceptible Streptococcus pyogenes infections may be due to biofilm formation. J Clin Microbiol 2006; 44:2721-2727.
22. Antonelli PJ, Lee JC, Burne RA. Bacterial biofilms may contribute to persistent cochlear implant infection. Otol Neurotol 2004; 25:953-957.
23. Pawlowski KS, Wawro D, Roland PS. Bacterial biofilm formation on a human cochlear implant. Otol Neurotol 2005; 26:972-975.
24. Loeffler KA, Johnson TA, Burne RA, Antonelli PJ. Biofilm formation in an in vitro model of cochlear implants with removable magnets. Otolaryngol Head Neck Surg 2007; 136:583-588. A nice demonstration that design modifications of cochlear implants could help reduce biofilm formation.
25. Johnson TA, Loeffler KA, Burne RA, et al. Biofilm formation in cochlear implants with cochlear drug delivery channels in an in vitro model. Otolaryngol Head Neck Surg 2007; 136:577-582.
26. Desrosiers M, Bendouah Z, Barbeau J. Effectiveness of topical antibiotics on Staphylococcus aureus biofilm in vitro. Am J Rhinol 2007; 21:149-153. Suggesting a new medical option for the treatment of CRS.
27. Chiu AG, Antunes MB, Palmer JN, Cohen NA. Evaluation of the in vivo efficacy of topical tobramycin against Pseudomonas sinonasal biofilms. J Antimicrob Chemother 2007; 59:1130-1134.
28. Regev-Yochay G, Dagan R, Raz M, et al. Association between carriage of Streptococcus pneumoniae and Staphylococcus aureus in children. JAMA 2004; 292:716-720.
29. Al-Shemari H, Abou-Hamad W, Libman M, Desrosiers M. Bacteriology of the sinus cavities of asymptomatic individuals after endoscopic sinus surgery. J Otolaryngol 2007; 36:43-48. An intriguing suggestion that beneficent biofilms may play a role in preventing recurrent disease.