Therapeutic failures of antibiotics used to treat macrolide-susceptible Streptococcus pyogenes infections may be due to biofilm formation

Journal of Clinical Microbiology

Volumn 44, Issue 8, 2006, Pages 2721-2727

  Baldassarri, Lucilla ^a   Creti, Roberta ^a   Recchia, Simona ^a   Imperi, Monica ^a   Facinelli, Bruna ^b   Giovanetti, Eleonora ^b   Pataracchia, Marco ^a   Alfarone, Giovanna ^a   Orefici, Graziella ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ERYTHROMYCIN; MACROLIDE; TETRACYCLINE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERIUM CARRIER; BACTERIUM ISOLATE; BIOFILM; CELL INVASION; CONTROLLED STUDY; DRUG RESPONSE; DRUG TREATMENT FAILURE; EMM GENE; EPITHELIUM CELL; ERM GENE; HOST PATHOGEN INTERACTION; HOST RESISTANCE; HUMAN; HUMAN CELL; MEFA GENE; NONHUMAN; PRIORITY JOURNAL; PRTF1 GENE; RECURRENT INFECTION; SEROTYPE; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PYOGENES;

ADHESINS, BACTERIAL; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BIOFILMS; CELL LINE, TUMOR; EPITHELIAL CELLS; ERYTHROMYCIN; HUMANS; MACROLIDES; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON, SCANNING; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PYOGENES;

STREPTOCOCCUS PYOGENES;

EID: 33747186343     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.00512-06     Document Type: Article

References (38)

1. Akiyama, H., S. Morizane, O. Yamasaki, T. Oono, and K. Iwatsuki. 2003. Assessment of Streptococcus pyogenes microcolony formation in infected skin by confocal laser scanning microscopy. J. Dermatol. Sci. 32:193-199.
2. Baldassarri, L., R. Cecchini, L. Bertuccini, M. G. Ammendolia, F. Iosi, C. R. Arciola, L. Montanaro, R. Di Rosa, G. Gherardi, G. Dicuonzo, G. Orefici, and R. Creti. 2001. Enterococcus spp. produces slime and survives in rat peritoneal macrophages. Med. Microbiol. Immunol. 190:113-120.
3. Baldassarri, L., S. Recchia, M. Imperi, R. Creti, G. Alfarone, M. Pataracchia, and G. Orefici. 2006. Fibronectin binding protein genes and cell invasion ability of Streptococcus pyogenes isolated from different sources. Int. Congr. Ser. 1289: 243-245.
4. Bisno, A. L., M. A. Gerber, J. M. Gwaltney, E. L. Kaplan, and R. H. Schwartz. 2002. Diagnosis and management of group A streptococcal pharyngitis: practice guidelines for streptococcal pharyngitis. Clin. Infect. Dis. 35:113-125.
5. Bisno, A. L., M. O. Brito, and C. M. Collins. 2003. Molecular basis of group A streptococcal virulence. Lancet Infect. Dis. 4:191-200.
6. Cardona, F., and G. Orefici. 2001. Group A streptococcal infections and tic disorders in an Italian pediatric population. J. Pediatr. 138:71-75.
7. Chaussee, M. S., J. Liu, D. L. Stevens, and J. J. Ferretti. 1997. Effects of environmental factors on streptococcal erythrogenic toxin A (speA) production by Streptococcus pyogenes. Adv. Exp. Med. Biol. 418:551-554.
8. Cho, K. H., and M. G. Caparon. 2005. Patterns of virulence gene expression differ between biofilm and tissue communities of Streptococcus pyogenes. Mol. Microbiol. 57:1545-1556.
9. Christensen, G. D., W. A. Simpson, J. J. Younger, L. M. Baddour, F. F. Barrett, D. M. Melton, and E. H. Beachey, 1985. Adherence of coagulase-negative staphylococci to plastic tissue culture plates: a quantitative model for the adherence of staphylococci to medical devices. J. Clin. Microbiol. 22:996-1006.
10. Conley, J., M. E. Olson, L. S. Cook, H. Crei, V. Phan, and H. D. Davies. 2003. Biofilm formation by group A streptococci: is there a relationship with treatment failure? J. Clin. Microbiol. 41:4043-4048.
11. Cornaglia, G., and A. Bryskier. 2004. Macrolide resistance of Streptococcus pyogenes, p. 150-165. In J. C. Pechere and E. L. Kaplan (ed.), Streptococcal pharyngitis. Karger, Basel, Switzerland.
12. Creti, R., F. Cardona, M. Pataracchia, C. von Hunolstein, G. Cundari, A. Romano, and G. Orefici. 2004. Characterisation of group A streptococcal (GAS) isolates from children with tic disorders. Indian J. Med. Res. 119: 174-178.
13. Creti, R., G. Gherardi, M. Imperi, C. von Hunolstein, L. Baldassarri, M. Pataracchia, G. Alfarone, F. Cardona, G. Dicuonzo, and G. Orefici. 2005. Association of group A streptococcal emm types with virulence traits and macrolide-resistance genes is independent of the source of isolation. J. Med. Microbiol. 54:913-917.
14. Cunningham, M. W. 2000. Pathogenesis of group A streptococcal infections. Clin. Microbiol. Rev. 13:470-511.
15. Donlan, R. M., and J. W. Costertoti. 2002. Biofilm: survival mechanisms of clinically relevant microorganisms. Clin. Microbiol. Rev. 15:167-193.
16. Ekelund, K., J. Darenberg, A. Norrby-Teglund, S. Hoffmann, D. Bang, P. Skinhoj, and H. B. Konradsen. 2005. Variations in emm type among group A streptococcal isolates causing invasive and noninvasive infections in a nationwide study. J. Clin. Microbiol. 43:3101-3109.
17. Ellen, R. P., G. Lepine, and P. M. Nghiem. 1997. In vitro models that support adhesion specificity in biofilms of oral bacteria. Adv. Dent. Res. 11:33-42.
18. Facinelli, B., C. Spinaci, G. Magi, E. Giovanetti, and P. E. Varaldo. 2001. Association between erythromycin resistance and ability to enter human respiratory cells in group A streptococci. Lancet 358:30-33.
19. Fischetti, V. A. 2000. Surface proteins on gram-positive bacteria, p. 11-24. In V. A. Fischetti, R. P. Novick, J. J. Ferretti, D. A. Portnoy, and J. I. Rood (ed.), Gram-positive pathogens. American Society for Microbiology, Washington, D.C.
20. Fogg, G. C., and M. G. Caparon. 1997. Constitutive expression of fibronectin binding in Streptococcus pyogenes as a result of anaerobic activation of rofA. J. Bacteriol. 179:6172-6180.
21. Gibson, C., G. Fogg, N. Okada, R. T. Geist, E. Hanski, and M. Caparon. 1995. Regulation of host cell recognition in Streptococcus pyogenes. Dev. Biol. Stand. 85:137-144.
22. Gillespie, S. H. 1998. Failure of penicillin in Streptococcus pyogenes pharyngeal infection. Lancet 352:1954-1956.
23. Giovanetti, E., A. Brenciani, R. Lupidi, M. C. Roberts, and P. E. Varaldo. 2003. Presence of the tet(O) gene in erythromycin- and tetracycline-resistant strains in Streptococcus pyogenes and linkage with either the mef(A) or the erm(A) gene. Antimicrob. Agents Chemother. 47:2844-2849.
24. Hidalgo-Grass, C., M. Dan-Goor, A. Maly, Y. Eran, L. A. Kwinn, V. Nizet, M. Ravins, J. Jaffe, A. Peyser, A. E. Moses, and E. Hanski. 2004. Effect of a bacterial pheromone peptide on host chemokine degradation in group A streptococcal necrotising soft-tissue infections. Lancet 363:696-703.
25. Jadoun, J., E. Ozeri, E. Burstein, E. Skutelsky, E. Hansky, and S. Sela. 1998. Protein F1 is required for efficient entry of Streptococcus pyogenes into epithelial cells. J. Infect. Dis. 178:147-158.
26. Jefferson, K. K. 2004. What drives bacteria to produce biofilm? FEMS Microbiol. Lett. 236:163-173.
27. Lembke, C., A. Podbielski, C. Hidalgo-Grass, L. Jonas, E. Hanski, and B. Kreikemeyer. 2006. Characterization of biofilm formation by clinically relevant serotypes of group A streptococci. Appl. Environ. Microbiol. 72:2864-2875.
28. Molinari, G., and G. S. Chhatwal. 1998. Invasion and survival of Streptococcus pyogenes in eukaryotic cells correlates with the source of clinical isolates. J. Infect. Dis. 177:1600-1607.
29. Natanson, S., S. Sela, A. E. Moses, J. M. Musser, M. G. Caparon, and E. Hanski. 1995. Distribution of fibronectin-binding proteins among group A streptococci of different M types. J. Infect. Dis. 171:871-878.
30. Neely, M. N., J. D. Pfeifer, and M. Caparon. 2002. Streptococcus- zebrafish model of bacterial pathogenesis. Infect. Immun. 70:3904-3914.
31. Neeman, R., N. Keller, A. Barzilai, Z. Korenman, and S. Sela. 1998. Prevalence of internalization-associated gene, prtF1, among persisting group A streptococcus strains isolated from asymptomatic carriers. Lancet 352:1974-1977.
32. O'Toole, G., H. B. Kaplan, and R. Kolter. 2000. Biofilm formation as microbial development. Annu. Rev. Microbiol. 40:445-450.
33. O'Toole, G. A., and R. Kolter. 1998. Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple convergent signalling pathways: a genetic analysis. Mol. Microbiol. 28:449-461.
34. Sela, S., R. Neeman, N. Keller, and A. Barzilai. 2000. Relationship between asymptomatic carriage of Streptococcus pyogenes and the ability of the strains to adhere and be internalised by cultured epithelial cells. J. Med. Microbiol. 49:499-502.
35. Spinaci, C., G. Magi, C. Zampaloni, L. A. Vitali, C. Paoletti, M. R. Catania, M. Prenna, L. Ferrante, S. Ripa, P. E. Varaldo, and B. Facinelli. 2004. Genetic diversity of cell-invasive erythromycin-resistant and -susceptible group A streptococci determined by analysis of the RD2 region of the prtF1 gene. J. Clin. Microbiol. 42:639-644.
36. Suligoi, B., C. von Hunolstein, G. Orefici, F. Scopetti, M. Pataracchia, and D. Greco. 1998. Surveillance of systemic invasive diseases caused by group A streptococcus in Italy 1994-1996. Euro Surveill. 3:11-14.
37. Varaldo, P. E., E. A. Debbia, G. Nicoletti, D. Pavesio, S. Ripa, G. C. Schito, G. Tempera, et al. 1999. Nationwide survey in Italy of treatment of Streptococcus pyogenes pharyngitis in children: influence of macrolide resistance on clinical and microbiological outcomes. Clin. Infect. Dis. 29:869-873.
38. von Hunolstein, C., B. Suligoi, M. Pataracchia, F. Scopetti, S. Recchia, D. Greco, and G. Orefici. 1997. Clinical and microbiological characteristics of severe group A streptococcal infections in Italy. Adv. Exp. Med. Biol. 418: 79-81.