The disturbance of the transduction of adenylyl cyclase inhibiting hormonal signal in myocardium and brain of rats with experimental type II diabetes

Tsitologiya

Volumn 49, Issue 6, 2007, Pages 442-450

  Shpakov, A O ^a   Kuznetsova, L A ^a   Plesneva, S A ^a   Pertseva, M N ^a  

^a SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

Author keywords

Adenylyl cyclase; Adenylyl cyclase signaling system; Brain; Diabetes; G protein; Myocardium; Relaxin; Somatostatin

Indexed keywords

ADENYLATE CYCLASE; ADRENALIN; BIOGENIC AMINE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; HORMONE; NORADRENALIN; RELAXIN; SEROTONIN; SOMATOSTATIN;

ANIMAL; ARTICLE; CORPUS STRIATUM; DISEASE MODEL; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; HEART; HEART MUSCLE; MALE; METABOLISM; NEWBORN; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOPHYSIOLOGY; PROTEIN BINDING; RAT; SIGNAL TRANSDUCTION; WISTAR RAT;

ADENYLATE CYCLASE; ANIMALS; ANIMALS, NEWBORN; BIOGENIC AMINES; CORPUS STRIATUM; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EPINEPHRINE; GTP-BINDING PROTEINS; GUANOSINE TRIPHOSPHATE; HEART; HORMONES; MALE; MYOCARDIUM; NOREPINEPHRINE; PROTEIN BINDING; RATS; RATS, WISTAR; RELAXIN; SEROTONIN; SIGNAL TRANSDUCTION; SOMATOSTATIN;

EID: 34548461182     PISSN: 00413771     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Russian source
2. Russian source
3. Russian source
4. Russian source
5. Begin-Heick N. 1994. Liver β-adrenergic receptors, G proteins, and adenylyl cyclase activity in obesity-diabetes syndromes. Amer. J. Physiol. 266: 1664-1672.
6. Breitweg-Lehmann E., Czupalla C., Storm R., Kudlacek O., Schunack W., Freissmuth M., Nurnberg B. 2002. Activation and inhibition of G protein by lipoamines. Mol. Pharmacol. 61 : 628-636.
7. iα-2 in hepatocytes. Biochem. J. 271 : 365-372.
8. i proteins. J. Cell. Biochem. 54 : 309-319.
9. i2 in vivo mimics insulin action. J. Mol. Med. 75 : 283-289.
10. 3-adrenoreceptors in rat hearts. Diabetes. 50 : 455-461.
11. Fernandez-Real J. M., Penarroja G., Richart C., Castro A., Vendrell J., Broch M., Lopez-Bermejo A., Ricart W. 2003. G protein β3 gene variant, vascular function, and insulin sensitivity in type 2 diabetes. Hypertension. 41 : 124-129.
12. Gando S., Hattori Y., Akaishi Y., Nishihira J., Kanno M. 1997. Impaired contractile response to beta adrenoreceptor stimulation in diabetic rat hearts: alterations in beta adrenoreceptors - G protein - adenylate cyclase system and phospholamban phosphorylation. J. Pharmacol. Exp. Ther. 282 : 475-484.
13. 3-AR in the human heart. J. Clin. Invest. 98 : 556-562.
14. i activity in diabetes. Nature. 327 : 229-232.
15. i protein activity in the diabetic retina. Eur. J. Pharmacol. 149 : 193-194.
16. Hajos F. 1974. An improved method for the preparation of synaptosomal fractions in high purity. Brain Res. 93 : 485-489.
17. Hashim S., Li Y., Anand-Srivastsva M. B. 2006. G-protein-linked cell signaling and cardiovascular functions in diabetes/hyperglycemia. Cell. Biochem. Biophys. 44 : 51-64.
18. Hashim S., Li Y., Nagakura A., Takeo S., Anand-Srivastava M. B. 2004. Modulation of G-protein expression and adenylyl cyclase signaling by high glucose in vascular smooth muscle. Cardiovasc. Res. 63 : 709-718.
19. Hashim S., Li Y. Y., Wang R., Anand-Srivastava M. B. 2002. Streptozotocin-induced diabetes impairs G-protein linked signal transduction in vascular smooth muscle. Mol. Cell. Biochem. 240 : 57-65.
20. Hattori Y., Matsuda N., Sato A., Watanuki S., Tomioka H., Kawasaki H., Kanno M. 2000. Predominant contribution of the G protein-mediated mechanism to NaF-induced vascular contractions in diabetic rats: association with an increased level of expression. J. Pharmacol. Exp. Ther. 292 : 761-768.
21. Hemmings S. J., Spafford D. 2000. Neonatal STZ model of type II diabetes mellitus in the Fischer 344 rat: characteristics and assessment of the status of the hepatic adrenergic receptors. Int. J. Biochem. Cell Biol. 32 : 905-919.
22. o by mastoparan, related amphiphilic peptides and hydrophobic amines. L. Biol. Chem. 265 : 14 176-14 186.
23. Kidwai A. M., Radcliffe A. M., Lee E. V., Daniel E. E. 1973. Isolation and properties of skeletal muscle membrane. Biochim. biophys. acta. 289 : 593-607.
24. Kowluru A., Kowluru R. A., Yamaraki A. 1992. Functional alterations of G-proteins in diabetic rat retina: a possible explanation for the early visual abnormalities in diabetes mellitus. Diabetologia. 35 : 624-631.
25. Kuznetsova L., Plesneva S., Shpakov A., Pertseva M. 2005. Functional defects in insulin and relaxin adenylyl cyclase signaling systems in myometrium of pregnant women with type I diabetes. Ann. N. Y. Acad. Sci. 1041 : 446-448.
26. Livingstone C., McLellan A. R., McGregor M., Wilson A., Connel J. M. C., Small M., Milligan G., Paterson K. R., Houslay M. D. 1991. Altered G-protein expression and adenylate cyclase activity in platelets of non-insulin-dependent (NIDDM) male subjects. Biochim. biophys. acta. 1096 : 127-133.
27. Malbon C C. 2004. Insulin signalling: putting the «G-» in protein-protein interactions. Biochem. J.380 : 11-12.
28. i-AR mRNA expression in rat heart. Biochem. Pharmacol. 58 : 881-885.
29. Matsumoto T., Wakabayashi K., Kobayashi T., Kamata K. 2005. Functional changes in adenylyl cyclases and associated in relaxation response in mesenteric arteries from diabetic rats. Amer. J. Physiol. Heart Circ. Physiol. 289 : 2234-2243.
30. j-adrenergic and A2a adenosine receptors. J. Biol. Chem. 276 : 15 801-15 809.
31. Missale C., Nash S. R., Robinson S. W., Jaber M., Caron M. G. 1998. Dopamine receptors: from structure to function. Physiol. Rev. 78 : 198-225.
32. iα2. Nature. 379 : 840-844.
33. i-coupled receptors in vivo. J. Biol. Chem. 271 : 33 308-33 316.
34. i function and stimulatory receptor-mediated regulation of adipocyte adenylyl cyclase in a model of insulin-resistant diabetes with obesity. Cell. Signal. 4 : 365-377.
35. Panchenko M. P., Hoffenberg S. I., Tkachuk V. A. 1987. Purification and some properties of GTP-binding proteins from pig heart plasma membranes. Biochim. biophys. acta. 46 : 452-455.
36. Plesneva S. A., Shpakov A. O., Kuznetsova L. A., Pertseva M. N. 2001. A dual role of protein kinase C in insulin signal transduction via adenylyl cyclase signaling system in muscle tissues of vertebrates. Biochem. Pharmacol. 61 : 1277-1291.
37. i in atrium of elderly diabetic subjects. Diabetes. 53 : 2392-2396.
38. Salomon Y., Londos C., Rodbell M. A. 1974. Highly sensitive adenylate cyclase assay. Anal. Biochem. 58 : 541-548.
39. Schreff M., Schulz S., Handel M., Keilhoff G., Braun E., Pereira G., Klutzny M., Schmidt H., Wolf G., Hollt V. 2000. Distribution, targeting, and internalization of the sst4 somatostatin receptor in rat brain. J. Neurosci. 20 : 3785-3797.
40. αi2 enhances in vivo activation of and insulin signaling to GLUT4. J. Biol. Chem. 276 : 34 651-34 658.
41. Wichelhaus A., Russ M., Petersen S., Eckel J. 1994. G protein expression and adenylate cyclase regulation in ventricular cardiomyocytes from STZ-diabetic rats. Amer. J. Physiol. 267 : 548-555.