Modulation of G-protein expression and adenylyl cyclase signaling by high glucose in vascular smooth muscle

Cardiovascular Research

Volumn 63, Issue 4, 2004, Pages 709-718

  Hashim, Shehla ^a   Li, Yuan ^a   Nagakura, Akira ^a   Takeo, Satoshi ^a   Anand Srivastava, Madhu B ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Adenylyl cyclase; Aorta; AVP; forskolin; FSK; G protein; Gi; Gs; GTP S; guanosine 5 thio triphosphate; Hyperglycemia; inhibitory guanine nucleotide regulatory protein; stimulatory guanine nucleotide regulatory protein; VSMC

Indexed keywords

ADENYLATE CYCLASE; ANGIOTENSIN; ANTIBODY; ATRIAL NATRIURETIC FACTOR; FLUORIDE SODIUM; FORSKOLIN; GLUCAGON; GLUCOSE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; OXOTREMORINE;

ANIMAL CELL; ANIMAL TISSUE; AORTA; ARTICLE; CARDIOVASCULAR DISEASE; CELL GROWTH; CELL MEMBRANE; CONTROLLED STUDY; CULTURE MEDIUM; DIABETES MELLITUS; EMBRYO; ENZYME ACTIVITY; ENZYME INHIBITION; EXPERIMENTAL RAT; HYPERGLYCEMIA; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; STATISTICAL SIGNIFICANCE; VASCULAR SMOOTH MUSCLE;

ADENYLATE CYCLASE; ANGIOTENSIN II; ANIMALS; AORTA; ATRIAL NATRIURETIC FACTOR; CELL LINE; GLUCOSE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; IMMUNOBLOTTING; MUSCLE, SMOOTH, VASCULAR; PEPTIDE FRAGMENTS; RATS; SIGNAL TRANSDUCTION;

EID: 4043137357     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2004.04.021     Document Type: Article

References (48)

1. Cowell J.A. Vascular thrombosis in type II diabetes mellitus. Diabetes. 32:1993;8-11
2. Givgliano D., Ceriello A., Paolisso G. Oxidative stress and diabetic vascular complications. Diabetes Care. 19:1996;257-267
3. Koya D., King G.L. Protein kinase C activation and the development of diabetic complications. Diabetes. 47:1998;859-866
4. Fleming J.W., Wisler P.L., Watanbe A.M. Signal transduction by G-proteins in cardiac tissues. Circulation. 85:1992;420-433
5. Neer E.J. Heterotrimeric G proteins. Organizers of transmembrane signals. Cell. 80:1995;249-257
6. Bray P., Caster A., Simons C., et al. Human cDNA clones for four species of Gsα signal transduction protein. Proc. Nat. Acad. Sci. U. S. A. 83:1986;8893-8897
7. Itoh H., Toyama R., Kozasa T., Tsukamoto T., Matsuoka M., Kaziro Y. Presence of three distinct molecular species of Gi protein: a subunit structure of rat cDNA and human genomic DNAs. J. Biol. Chem. 263:1988;6656-6664
8. Wong Y.H., Conklin B.B., Bourne H.R. Gi-mediated hormonal inhibition of cyclic AMP accumulation. Science. 255:1992;339-342
9. + channels is stimulated by three distinct Giα subunits. Nature. 336:1988;680-682
10. Anand-Srivastava M.B. Enhanced expression of inhibitory guanine nucleotide regulatory protein in spontaneously hypertensive rats: relationship to adenylate cyclase inhibition. Biochem. J. 288:1992;79-85
11. Anand-Srivastava M.B., de Champlain J., Thibault C. DOCA-salt hypertensive rat hearts exhibit altered expression of G-proteins. Am. J. Hypertens. 6:1993;72-75
12. Feldman A.M., Cates A.E., Veazey W.B., et al. Increase of the 40,000 mol wt pertussis toxin substrate (G-protein) in the failing human heart. J. Clin. Invest. 82:1988;189-197
13. Tucek S., Michal P., Vlachova V. Dual effects of muscarinic M2 receptors on the synthesis of cAMP in CHO cells: background and model. Life Sci. 68:2001;2501-2510
14. Moxham C.M., Malbon C.C. Insulin action impaired by deficiency of the G-protein subunit Gi alpha 2. Nature. 379:1996;840-844
15. Zheng X.L., Guo J., Wang H.Y., Malbon C.C. Expression of constitutively activated Gialpha 2 in vivo ameliorates streptozotocin induced diabetes. J. Biol. Chem. 273:1998;23649-23651
16. Gawler D., Milligan G., Spiegel A.M., Unson C.G., Houslay M.D. Abolition of expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes. Nature. 327:1987;229-232
17. Palmer G.C., Wilson G.L., Chronister R.B. Streptozotocin-induced diabetes produces alterations in adenylate cyclase in rat cerebrum, cerebral microvessels and retina. Life Sci. 24:1983;365-374
18. Strassheim D., Palmer T., Houslay M.D. Diabetes abolishes the GTP-dependent, but not the receptor-dependent inhibitory function of the inhibitory guanine-nucleotide-binding regulatory protein (Gi) on adipocyte adenylate cyclase activity. Biochem. J. 266:1990;521-526
19. Hashim S., Liu Y.Y., Wang R., Anand-Srivastava M.B. Streptozotocin- induced diabetes impairs G-protein-linked signal transduction in vascular smooth muscle. Mol. Cell. Biochem. 240:2002;57-65
20. Kimes B.W., Brandt B.L. Properties of a clonal muscle cell line from rat heart. Exp. Cell Res. 98:1976;349-366
21. Palaparti A., Chang G., Anand-Srivastava M.B. Angiotensin II enhances the expression of Giα in A10 cells (smooth muscle): relationship with adenylyl cyclase activity. Arch. Biochem. Biophys. 365:1999;113-122
22. Jones D.T., Reed R. Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium. J. Biol. Chem. 262:1987;14241-14249
23. Anand-Srivastava M.B., Srivastava A.K., Cantin M. Pertussis toxin attenuates atrial natriuretic factor-mediated inhibition of adenylyl cyclase. Involvement of inhibitory guanine nucleotide regulatory protein. J. Biol. Chem. 262:1987;4931-4934
24. Anand-Srivastava M.B. Angiotensin II receptor are negatively coupled to adenylyl cyclase in rat myocardial sarcolemma. Involvement of inhibitory guanine nucleotide regulatory protein. Biochem. Pharmacol. 38:1989;489-496
25. Cerione R.A., Stamiszewsk C., Caron M.G., Lefkowitz R.J., Codina J., Birnbaumer L. A role for Ni in the hormonal stimulation of adenylylate cyclase. Nature. 318:1985;293-295
26. Mancusi G., Hutter C., Baumgartner P.S., Schmidt K., Schütz W., Sexl V. High-glucose incubation of human unbilical-vein endothelial cells does not alter expression and function either of G protein α-subunit or of endothelial NO synthase. Biochem. J. 315:1996;281-287
27. Bushfield M., Griffiths S.L., Murphy G.J., et al. Diabetes-induced alterations in the expression, functioning and phosphorylation state of the inhibitory guanine nucleotide regulatory protein Giα-2 in hepatocytes. Biochem. J. 271:1990;365-372
28. Carro J.F., Raju M.S., Caro M., et al. Evidence for altered cross-talk≫ between the insulin receptor and Gi proteins. J. Cell Biochem. 54:1994;309-319
29. Livingstone C., McLellan A.R., McGregor M.-A., et al. Altered G-protein expression and adenylate cyclase activity in platelets of non-insulin-dependent (NIDDM) male subjects. Biochim. Biochem. Acta. 1096:1991;127-133
30. Hadjiconstantinou M., Ou Z.K., Moroi-Fetters S.E., Neff N.H. Apparent loss of Gi protein activity in diabetic retina. Eur. J. Pharmacol. 149:1988;193-194
31. Strassheim D., Palmer T., Houslay M.D. Genetically acquired diabetes: adipocyte guanine nucleotide regulatory protein expression and adenylyl cyclase regulation. Biochim. Biophys. Acta. 1096:1991;121-126
32. Weber L.P., Macleod K.M. Influence of streptozotocin diabetes on the alpha-1 adrenoceptor and associated G-protein in rat arteries. J. Pharmacol. Exp. Ther. 283:1997;1469-1478
33. Griffiths S.L., Knowler J.T., Housley M.D. Diabetes-induced changes in guanine nucleotide regulatory protein mRNA detected using synthetic oligonucleotide probes. Eur. J. Biochem. 193:1990;367-374
34. Phan H.H., Boissard C., Pessah M., et al. Decreased ADP-ribosylation of the Galpha (olf) and Galpha (s) subunits by high glucose in pancreatic β-cells. Biochem. Biophys. Res. Commun. 271:2000;86-90
35. Parson W.J., Stiles G.L. Heterologous desensitization of the inhibitory A1 adenosine receptor-adenylate cyclase system in rat adipocytes. Regulation of both Ns and Ni. J. Biol. Chem. 262(2):1987;841-847
36. Anand-Srivastava M.B. Downregulation of atrial natriuretic peptide ANP-C receptor is associated with alterations in G-protein expression in A10 smooth muscle cells. Biochemistry. 39:2000;6503-6513
37. Reithmann C., Gierschik P., Werden K., Jakobs K.H. Hormonal regulation of Gi alpha level and adenylyl cyclase responsiveness. Brit. J. Clin. Pharmacol. Suppl. 1:1990;118S-120S
38. Kook H., Lee J.U., Kim S.W., Kim S.W., Baik Y.H. Augmented natriuretic peptide-induced guanylyl cyclase activity and vasodilatation in experimental hyperglycemic rats. Jpn. J. Pharmacol. 88:2002;167-173
39. Williams B., Tsai P., Schrier R.W. Glucose-induced downregulation of angiotensin II and arginine vasopressin receptors in cultured rat aortic vascular smooth muscle cells. Role of protein kinase C. J. Clin. Invest. 90:1992;1992-1999
40. + channel current in rat small coronary arteries. Circ. Res. 89:2001;146-152
41. Kowluru A., Kowluru R.A., Yamaraki A. Functional alterations of G-proteins in diabetic rat retina: a possible explanation of the early visual abnormalities in diabetes mellitus. Diabetelogia. 35:1992;624-631
42. Hayashi S., Morishuta R., Matsusluta H., et al. Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells accompanied by induction of P53 and P21. Hypertension. 35:2000;237-243
43. Fujita N., Furukawa Y., Du J., et al. Hyperglycemia enhances VSMC proliferation with NF-kappa β activation by angiotensin II and E2F-1 augmentation by growth factors. Mol. Cell Endocrinol. 792:2002;75-84
44. Gando S., Hattori Y., Akaishi Y., Nishihira J., Kanno M. Impaired contractile response to beta adrenoceptor stimulation in diabetic rat hearts: alterations in beta adrenoceptors-G-protein adenylyl cyclase system and phospholamban phosphorylation. J. Pharmacol. Exp. Ther. 282:1997;475-484
45. Komabayashi T., Ideka T., Suda K., Izawa T. Beta-adrenergic receptors and adenylate cyclase activity in parotid acinar cells from acute streptozotocin induced diabetic rats. Res. Commun. Mol. Pathol. Pharmacol. 107:2000;311-322
46. Anand-Srivastava M.B. Amiloride interacts with guanine nucleotide regulatory proteins and attenuates the hormonal inhibition of adenylate cyclase. J. Biol. Chem. 264:1989;9491-9496
47. Anand-Srivastava M.B. Rat platelets from spontaneously hypertensive rats exhibit decreased expression of inhibitory guanine nucleotide regulatory protein: relationship with adenylate cyclase activity. Circ. Res. 73:1993;1032-1039
48. Marcil J., Schiffrin E.L., Anand-Srivastava M.B. Aberrant adenylyl cyclase/cAMP signal transduction system and G protein levels in platelets from hypertensive patients: improve with antihypertensive drug therapy. Hypertension. 28:1996;83-90