The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria

Protein Science

Volumn 16, Issue 9, 2007, Pages 1896-1904

  Graña, Martin ^a   Haouz, Ahmed ^a   Buschiazzo, Alejandro ^a,c   Miras, Isabelle ^a   Wehenkel, Annemarie ^a   Bondet, Vincent ^a   Shepard, William ^a,b   Schaeffer, Francis ^a   Cole, Stewart T ^a   Alzari, Pedro M ^a  

^a INSTITUT PASTEUR   (France)

^b SYNCHROTRON SOLEIL   (France)

^c INSTITUT PASTEUR DE MONTEVIDEO   (Uruguay)

Author keywords

Function discovery; Mycobacterium leprae; S adenosylmethionine dependent methyltransferase; X ray crystallography

Indexed keywords

AMINO ACID; BACTERIAL PROTEIN; GENOMIC DNA; METHYLTRANSFERASE; S ADENOSYLMETHIONINE;

ARTICLE; BACTERIAL STRAIN; BINDING SITE; CATALYSIS; CRYSTAL STRUCTURE; GENOMICS; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR CLONING; MYCOBACTERIUM LEPRAE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; BINDING SITES; COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; DATABASES, PROTEIN; ELECTROSTATICS; METHYLTRANSFERASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIACEAE; MYCOBACTERIUM LEPRAE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; S-ADENOSYLMETHIONINE; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

CORYNEBACTERINEAE; MYCOBACTERIUM LEPRAE;

EID: 34548460327     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.072982707     Document Type: Article

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