Antibodies to the 70 kDa heat shock protein in midtrimester amniotic fluid and intraamniotic immunity

American Journal of Obstetrics and Gynecology

Volumn 197, Issue 3, 2007, Pages 278.e1-278.e4

  Gelber, Shari E ^a,b   Bongiovanni, Ann Marie ^a,b   Jean Pierre, Claudel ^a,b   Linhares, Iara M ^a,b   Skupski, Daniel W ^a,b   Witkin, Steven S ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b NEW YORK HOSPITAL QUEENS   (United States)

Author keywords

amniotic fluid; heat shock protein; heat shock protein antibodies; immune regulation; interferon ; secretory leukocyte protease inhibitor; tumor necrosis factor

Indexed keywords

ALPHA INTERFERON; ANTIGEN; BIOLOGICAL MARKER; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN G; PROTEIN ANTIBODY; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AMNIOCENTESIS; AMNION FLUID; ARTICLE; CONCENTRATION RESPONSE; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ETHNICITY; FEMALE; FETUS DEVELOPMENT; HUMAN; IMMUNE RESPONSE; IMMUNITY; IMMUNOREGULATION; MATERNAL AGE; MICROBIAL IMMUNITY; OUTCOME ASSESSMENT; PARITY; PREGNANCY OUTCOME; PRIORITY JOURNAL; PROTEIN CROSS LINKING; RACE; SECOND TRIMESTER PREGNANCY; STATISTICAL ANALYSIS;

EID: 34548444214     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2007.06.019     Document Type: Article

References (22)

1. Lindquist S., and Craig E.A. The heat-shock proteins. Annu Rev Genet 22 (1988) 631-677
2. Campisi J., Leem T.H., and Fleshner M. Stress-induced extracellular Hsp72 is a functionally significant danger signal to the immune system. Cell Stress Chaperones 8 (2003) 272-286
3. Vabulas R.M., Wagner H., and Schild H. Heat shock proteins as ligands of toll-like receptors. Curr Top Microbiol Immunol 270 (2002) 169-184
4. Becker T., Hartl F.U., and Wieland F. CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes. J Cell Biol 158 (2002) 1277-1285
5. Srivastava P. Role of heat-shock proteins in innate and adaptive immunity. Nat Rev Immunol 2 (2002) 185-194
6. Tishler M., and Shoenfeld Y. Anti-heat-shock protein antibodies in rheumatic and autoimmune diseases. Semin Arthritis Rheum 26 (1996) 558-563
7. Chiba S., Yokota S., Yonekura K., et al. Autoantibodies against HSP70 family proteins were detected in the cerebrospinal fluid from patients with multiple sclerosis. J Neurol Sci 241 (2006) 39-43
8. Xu Q. Role of heat shock proteins in atherosclerosis. Artioscler Thromb Vasc Biol 22 (2002) 1547-1559
9. Yokota S., Minota S., and Fujii N. Anti-HSP auto-antibodies enhance HSP-induced pro-inflammatory cytokine production in human monocytic cells via Toll-like receptors. Int Immunol 18 (2006) 573-580
10. Jean-Pierre C., Perni S.C., Bongiovanni A.M., et al. Extracellular 70-kd heat shock protein in mid-trimester amniotic fluid and its effect on cytokine production by ex vivo-cultured amniotic fluid cells. Am J Obstet Gynecol 194 (2006) 694-698
11. Shah M., Stanek J., and Handwerger S. Differential localization of heat shock proteins 90, 70, 60 and 27 in human decidua and placenta during pregnancy. Histochem J 30 (1998) 509-518
12. Perni S.C., Kalish R.B., Hutson J.M., et al. Differential expression of immune system-related components in midtrimester amniotic fluid from singleton and twin pregnancies. Am J Obstet Gynecol 193 (2005) 942-946
13. Perni S.C., Vardhana S., Kalish R., Chasen S., and Witkin S.S. Clara cell protein 16 concentration in mid-trimester amniotic fluid: Association with fetal gender, fetal G>A +38 CC16 gene polymorphism and pregnancy outcome. J Reprod Immunol 68 (2005) 85-90
14. Child D.F., Hudson P.R., Hunter-Lavin C., et al. Birth defects and anti-heat shock protein 70 antibodies in early pregnancy. Cell Stress Chaperones 11 (2006) 101-105
15. Ziegert M., Witkin S.S., Sziller I., Alexander H., Brylla E., and Hartig W. Heat shock proteins and heat shock protein-antibody complexes in placental tissues. Infect Dis Obstet Gynecol 7 (1999) 180-185
16. Pockley A.G., de Faire U., Kiessling R., Lemne C., Thulin T., and Frostegard J. Circulating heat shock protein and heat shock protein antibody levels in established hypertension. J Hypertens 20 (2002) 1815-1820
17. Xhang Q., Shimoya K., Moriyama A., et al. production of secretory leukocyte protease inhibitor by human amniotic membranes and regulation of its concentration in amniotic fluid. Mol Hum Reprod 7 (2001) 573-579
18. King A.E., Critchley H.O.D., and Kelly R.W. Presence of secretory leukocyte protease inhibitor in human endometrium and first trimester decidua suggests an antibacterial protective role. Mol Hum Reprod 6 (2000) 191-196
19. Song X., Jin W., Thompson J., Mizel D.E., Lei K., Billinghurst R.C., et al. Secretory leukocyte protease inhibitor suppresses the inflammation and joint damage of bacterial cell wall-induced arthritis. J Exp Med 190 (1999) 535-542
20. Theofilopoulos A.N., Baccala R., Beutler B., and Kono D.H. Type I interferons (α/β) in immunity and autoimmunity. Annu Rev Immunol 23 (2005) 307-336
21. Hu X., Ho H.H., Lou O., Hidaka C., and Ivashkiv L.B. Homeostatic role of interferons conferred by inhibition of IL-1-mediated inflammation and tissue destruction. J Immunol 175 (2005) 131-138
22. Wu T., and Tanguay R.M. Antibodies against heat shock proteins in environmental stresses and diseases: friend or foe?. Cell Stress Chaperones 11 (2006) 1-12