Destabilization of human glycine N-methyltransferase by H176N mutation

Protein Science

Volumn 16, Issue 9, 2007, Pages 1957-1964

  Luka, Zigmund ^a   Pakhomova, Svetlana ^b   Luka, Yury ^c   Newcomer, Marcia E ^b   Wagner, Conrad ^a,d  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUISIANA STATE UNIVERSITY   (United States)

^c Economic Research Institute   (Belarus)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Glycine N methyltransferase; Mutant; Quaternary structure; Stability; Unfolding; Urea

Indexed keywords

GLYCINE METHYLTRANSFERASE; TETRAMER;

ARTICLE; CIRCULAR DICHROISM; ENERGY; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; GEL PERMEATION CHROMATOGRAPHY; HUMAN; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE; THERMODYNAMICS;

CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME STABILITY; GLYCINE N-METHYLTRANSFERASE; HUMANS; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, QUATERNARY; SPECTROMETRY, FLUORESCENCE; THERMODYNAMICS; UREA;

EID: 34548435697     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.072921507     Document Type: Article

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