Time course and quantification of pancreatic islet revasculariztion following intraportal transplantation

Cell Transplantation

Volumn 16, Issue 5, 2007, Pages 505-516

  Jones, Gareth L ^a   Juszczak, Maciej T ^a   Hughes, Stephen J ^a   Kooner, Paul ^a   Powis, Stephen H ^a   Press, Martin ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Endothelium; Islet transplantation; Quantification; Vascular density

Indexed keywords

INSULIN; LECTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DENSITY; CELL STRUCTURE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REVASCULARIZATION; ANGIOGENESIS; ANIMAL; CYTOLOGY; GLUCOSE BLOOD LEVEL; LEWIS RAT; PORTAL VEIN; TIME; VASCULARIZATION;

BANDEIRAEA SIMPLICIFOLIA; RATTUS;

ANIMALS; BLOOD GLUCOSE; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; NEOVASCULARIZATION, PHYSIOLOGIC; PORTAL SYSTEM; RATS; RATS, INBRED LEW; TIME FACTORS;

EID: 34548435093     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/000000007783464993     Document Type: Article

References (43)

1. Barrett, J. M.; Mangold, K. A.; Jilling, T.; Kaul, K. L. Bidirectional interactions of prostate cancer cells and bone marrow endothelial cells in three-dimensional culture. Prostate 64(1):75-82; 2005.
2. Beger, C.; Cirulli, V.; Vajkoczy, P.; Halban, P. A.; Menger, M. D. Vascularization of purified pancreatic islet-like cell aggregates (pseudoislets) after syngeneic transplantation. Diabetes 47(4):559-565; 1998.
3. Bernsen, H. J.; Rijken, P. F.; Hagemeier, N. E.; van der Kogel, A. J. A quantitative analysis of vascularization and perfusion of human glioma xenografts at different implantation sites. Microvasc. Res. 57(3):244-257; 1999.
4. Biarnes, M.; Montolio, M.; Nacher, V.; Raurell, M.; Soler, J.; Montanya, E. Beta-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia. Diabetes 51(1):66-72; 2002.
5. Bonner-Weir, S.; Orci, L. New perspectives on the microvasculature of the islets of Langerhans in the rat. Diabetes 31(10):883-889; 1982.
6. Carlsson, P. O.; Mattsson, G. Oxygen tension and blood flow in relation to revascularization in transplanted adult and fetal rat pancreatic islets. Cell Transplant. 11(8):813-820; 1993.
7. Carlsson, P. O.; Palm, F.; Andersson, A.; Liss, P. Chronically decreased oxygen tension in rat pancreatic islets transplanted under the kidney capsule. Transplantation 69(5):761-766; 2000.
8. Carlsson, P. O.; Palm, F.; Andersson, A.; Liss, P. Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site. Diabetes 50(3):489-495; 2001.
9. Carlsson, P. O.; Palm, F.; Mattsson, G. Low revascularization of experimentally transplanted human pancreatic islets. J. Clin. Endocrinol. Metab. 87(12):5418-5423; 2002.
10. Chiarotto, J. A.; Hill, R. P. A quantitative analysis of the reduction in oxygen levels required to induce up-regulation of vascular endothelial growth factor (VEGF) mRNA in cervical cancer cell lines. Br. J. Cancer 80(10):1518-1524; 1999.
11. Davalli, A. M.; Scaglia, L.; Zangen, D. H.; Hollister, J.; Bonner-Weir, S.; Weir, G. C. Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function. Diabetes 45(9):1161-1167; 1996.
12. Fox, S. B.; Leek, R. D.; Weekes, M. P.; Whitehouse, R. M.; Gatter, K. C.; Harris, A. L. Quantitation and prognostic value of breast cancer angiogenesis: Comparison of microvessel density, Chalkley count, and computer image analysis. J. Pathol. 177(3):275-283; 1995.
13. Fukumura, D.; Yuan, F.; Monsky, W. L.; Chen, Y.; Jain, R. K. Effect of host microenvironment on the microcirculation of human colon adenocarcinoma. Am. J. Pathol. 151(3):679-688; 1997.
14. Goddard, J. C.; Sutton, C. D.; Berry, D. P.; O'Byrne, K. J.; Kockelbergh, R. C. The use of microvessel density in assessing human urological tumours. BJU Int. 87(9):866-875; 2001.
15. Gouysse, G.; Couvelard, A.; Frachon, S.; Bouvier, R.; Nejjari, M.; Dauge, M. C.; Feldmann, G.; Henin, D.; Scoazec, J. Y. Relationship between vascular development and vascular differentiation during liver organogenesis in humans. J. Hepatol. 37(6):730-740; 2002.
16. Griffith, R. C.; Scharp, D. W.; Hartman, B. K.; Ballinger, W. F.; Lacy, P. E. A morphologic study of intrahepatic portal-vein islet isografts. Diabetes 26(3):201-214; 1977.
17. Hara, M.; Yin, D.; Dizon, R. F.; Shen, J.; Chong, A. S.; Bindokas, V. P. A mouse model for studying intrahepatic islet transplantation. Transplantation 78(4):615-618; 2004.
18. Huang, M. T.; Mason, J. C.; Birdsey, G. M.; Amsellem, V.; Gerwin, N.; Haskard, D. O.; Ridley, A. J.; Randi, A. M. Endothelial intercellular adhesion molecule (ICAM)-2 regulates angiogenesis. Blood 106(5):1636-1643; 2005.
19. Hughes, S. J.; Davies, S. E.; Powis, S. H.; Press, M. Hyperoxia improves the survival of intraportally transplanted syngeneic pancreatic islets. Transplantation 75(12):1954-1959; 2003.
20. Jiang, B. H.; Semenza, G. L.; Bauer, C.; Marti, H. H. Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. Am. J. Physiol. 271(4 Pt. 1):C1172-1180; 1996.
21. Jones, G. L.; Juszczak, M. T.; Hughes, S. J.; Powis, S. H.; Press, M. An improved method of fluorescent dual insulin and endothelial staining allows visualisation of the revascularisation of intraportally transplanted islets. Transplant. Proc. 37(8):3509-3511; 2005.
22. Lai, Y.; Schneider, D.; Kidszun, A.; Hauck-Schmalenberger, I.; Breier, G.; Brandhorst, D.; Brandhorst, H.; Iken, M.; Brendel, M. D.; Bretzel, R. G.; et al. Vascular endothelial growth factor increases functional beta-cell mass by improvement of angiogenesis of isolated human and murine pancreatic islets. Transplantation 79(11):1530-1536; 2005.
23. Lifson, N.; Lassa, C. V.; Dixit, P. K. Relation between blood flow and morphology in islet organ of rat pancreas. Am. J. Physiol. 249(1 Pt. 1):E43-48; 1985.
24. Liu, Y. M.; Guth, P. H.; Kaneko, K.; Livingston, E. H.; Brunicardi, F. C. Dynamic in vivo observation of rat islet microcirculation. Pancreas 8(1):15-21; 1993.
25. Mattsson, G.; Carlsson, P. O.; Olausson, K.; Jansson, L. Histological markers for endothelial cells in endogenous and transplanted rodent pancreatic islets. Pancreatology 2(2):155-162; 2002.
26. Mattsson, G.; Jansson, L.; Carlsson, P. O. Decreased vascular density in mouse pancreatic islets after transplantation. Diabetes 51(5):1362-1366; 2002.
27. Mattsson, G.; Jansson, L.; Nordin, A.; Carlsson, P. O. Impaired revascularization of transplanted mouse pancreatic islets is chronic and glucose-independent. Transplantation 75(5):736-739; 2003.
28. Mucke, I.; Richter, S.; Menger, M. D.; Vollmar, B. Significance of hepatic arterial responsiveness for adequate tissue oxygenation upon portal vein occlusion in cirrhotic livers. Int. J. Colorectal Dis. 15(5-6):335-341; 2000.
29. Oda, M.; Yokomori, H.; Han, J. Y. Regulatory mechanisms of hepatic microcirculation. Clin. Hemorheol. Microcirc. 29(3-4):167-182; 2003.
30. Olsson, R.; Carlsson, P. O. Better vascular engraftment and function in pancreatic islets transplanted without prior culture. Diabetologia 48(3):469-476; 2005.
31. Radinsky, R.; Ellis, L. M. Molecular determinants in the biology of liver metastasis. Surg. Oncol. Clin. N. Am. 5(2):215-229; 1996.
32. Risau, W. Mechanisms of angiogenesis. Nature 386(6626):671-674; 1997.
33. Rooth, P.; Dawidson, I.; Lafferty, K.; Diller, K.; Armstrong, J.; Pratt, P.; Simonsen, R.; Taljedal, I. B. Prevention of detrimental effect of cyclosporin A on vascular ingrowth of transplanted pancreatic islets with verapamil. Diabetes 38(Suppl. 1):202-205; 1989.
34. Sawant, S.; Aparicio, S.; Tink, A. R.; Lara, N.; Barnstable, C. J.; Tombran-Tink, J. Regulation of factors controlling angiogenesis in liver development: A role for PEDF in the formation and maintenance of normal vasculature. Biochem. Biophys. Res. Commun. 325(2):408-413; 2004.
35. Schurek, H. J.; Jost, U.; Baumgartl, H.; Bertram, H.; Heckmann, U. Evidence for a preglomerular oxygen diffusion shunt in rat renal cortex. Am. J. Physiol. 259(6 Pt. 2):F910-915; 1990.
36. Shapiro, A. M.; Lakey, J. R.; Ryan, E. A.; Korbutt, G. S.; Toth, E.; Warnock, G. L.; Kneteman, N. M.; Rajotte, R. V. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N. Engl. J. Med. 343(4):230-238; 2000.
37. Sharma, S.; Sharma, M. C.; Sarkar, C. Morphology of angiogenesis in human cancer: A conceptual overview, histoprognostic perspective and significance of neoangiogenesis. Histopathology 46(5):481-489; 2005.
38. Vajkoczy, P.; Farhadi, M.; Gaumann, A.; Heidenreich, R.; Erber, R.; Wunder, A.; Tonn, J. C.; Menger, M. D.; Breier, G. Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2. J. Clin. Invest. 109(6):777-785; 2002.
39. Vajkoczy, P.; Olofsson, A. M.; Lohr, H. A.; Leiderer, R.; Hammersen, F.; Arfors, K. E.; Menger, M. D. Histogenesis and ultrastrusture of pancreatic Islet graft microvasculature: Evidence for graft revascularisation by endothelial cells of host origin. Am. J. Pathol. 146:1397-1405; 1995.
40. Vajkoczy, P.; Menger, M.; Simpson, E.; Messmer, K. Angiogenesis and vascularisation of murine pancreatic islet isografts. Transplantation 60:123-127; 1995.
41. Vasir, B.; Jonas, J. C.; Steil, G. M.; Hollister-Lock, J.; Hasenkamp, W.; Sharma, A.; Bonner-Weir, S.; Weir, G. C. Gene expression of VEGF and its receptors Flk-1/KDR and Flt-1 in cultured and transplanted rat islets. Transplantation 71(7):924-935; 2001.
42. Vermeulen, P. B.; Gasparini, G.; Fox, S. B.; Colpaert, C.; Marson, L. P.; Gion, M.; Belien, J. A.; de Waal, R. M.; Van Marck, E.; Magnani, E.; et al. Second international consensus on the methodology and criteria of evaluation of angiogenesis quantification in solid human tumours. Eur. J. Cancer 38(12):1564-1579; 2002.
43. Weidner, N.; Semple, J. P.; Welch, W. R.; Folkman, J. Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma. N. Engl. J. Med. 324(1):1-8; 1991.