Acute pulmonary hemorrhage during isoflurane anesthesia in two cats exposed to toxic black mold (Stachybotrys chartarum)

Journal of the American Veterinary Medical Association

Volumn 231, Issue 5, 2007, Pages 731-735

  Mader, Douglas R ^a   Yike, Iwona ^b   Distler, Anne M ^b   Dearborn, Dorr G ^b  

^a Marathon Veterinary Hospital   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INHALATION ANESTHETIC AGENT; ISOFLURANE; MYCOTOXIN;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLEEDING; CASE REPORT; CAT; CAT DISEASE; FATALITY; FEMALE; LUNG DISEASE; MALE; MICROBIOLOGY; MYCOSIS; PATHOGENICITY; STACHYBOTRYS;

AIR MICROBIOLOGY; ANESTHETICS, INHALATION; ANIMALS; CAT DISEASES; CATS; FATAL OUTCOME; FEMALE; HEMORRHAGE; ISOFLURANE; LUNG DISEASES; MALE; MYCOSES; MYCOTOXINS; STACHYBOTRYS;

ANIMALIA; STACHYBOTRYS CHARTARUM;

EID: 34548432512     PISSN: 00031488     EISSN: None     Source Type: Journal    
DOI: 10.2460/javma.231.5.731     Document Type: Article

References (26)

1. Birks EK, Durando MM, McBride S. Exercise-induced pulmonary hemorrhage. Vet Clin North Am Equine Pract 2003;19:87-100.
2. Yike I, Distler AM, Ziady AG, et al. Mycotoxin adducts on human serum albumin: biomarkers of exposure to Stachybotrys chartarum. Environ Health Perspect 2006;114:1221-1226.
3. Tripi PA, Modlin S, Sorenson WG, et al. Acute pulmonary hemorrhage in an infant during induction of general anesthesia. Paediatr Anesth 2000;10:92-94.
4. Etzel RA, Dearborn DG. Pulmonary hemorrhage among infants with exposure to toxigenic molds: an update. In: Johanning E, ed. Bioaerosols, fungi, and mycotoxins: health effect, assessment, prevention and control. Albany, NY: Boyd Printing Co Inc, 1999;79-83.
5. Rossaint R, Cerny V, Coats TJ, et al. Key issues in advanced bleeding care in trauma. Shock 2006;4:322-331.
6. DeHeer HL, McManus P. Frequency and severity of tracheal wash hemosiderosis and association with underlying disease in 96 cats: 2002-2003. Vet Clin Pathol 2005;34:17-22.
7. Edwards DF, Russell RG. Probable vitamin K-deficient bleeding in two cats with malabsorption syndrome secondary to lymphocytic-plasmacytic enteritis. J Vet Intern Med 1987;1:97-101.
8. DuVall MD, Murphy MJ, Ray AC, et al. Case studies in second-generation anticoagulant rodenticide toxicities in nontarget species. J Vet Diagn Invest 1989;1:66-68.
9. Hurley KE, Pesavento PA, Pedersen NC, et al. An outbreak of virulent systemic feline calicivirus disease. J Am Vet Med Assoc 2004;224:241-249.
10. Cowles BE, Meyers KM, Wardrop KJ, et al. Prolonged bleeding time of Chediak-Higashi cats corrected by platelet transfusion. Thromb Haemost 1992;67:708-712.
11. Tripi P, Thomas S, Dearborn DG. Management of general anesthesia in infants and children with a history of idiopathic pulmonary haemorrhage. Paediatr Anaesth 2002;12:243-247.
12. Yike I, Dearborn DG. Pulmonary effects of Stachybotrys chartarum in animal studies. In: Strauss D, ed. Advances in applied microbiology, sick building syndrome. St Louis: Elsevier, 2004;241-273.
13. Yike I, Rand TG, Dearborn DG. Acute inflammatory responses to Stachybotrys chartarum in the lungs of infant rats: time course and possible mechanisms. Toxicol Sci 2005;84:408-417.
14. Dearborn DG, Smith PG, Dahms BB, et al. Clinical profile of thirty infants with acute idiopathic pulmonary hemorrhage in Cleveland. Pediatrics 2002;110:627-637.
15. Hart MA, Dearborn DG. Diffuse alveolar hemorrhage (pulmonary hemosiderosis). In: Burg F, Ingelfinger J, Polin R, et al, eds. Current pediatric therapy. 18th ed. Philadelphia: WB Saunders Co, 2006;1455-1457.
16. Jarvis BB, Salemme J, Morais A. Stachybotrys toxins. Nat Toxins 1995;3:10-16.
17. Feinberg B, MacLaughlin CS. Biochemical mechanism of action of trichothecene mycotoxins. In: Beasley VR, ed. Trichothecene mycotoxicosis: pathophysiologic effects. Vol 1. Boca Raton, Fla: CRC Press, 1989;27-36.
18. Jarvis BB, Sorenson WB, Hintikka E-L, et al. Studies of toxin production by isolates of Stachybotrys atra and Memnoniella echinata isolated from homes associated with pulmonary hemosiderosis in infants. Appl Environ Microbiol 1998;64:3620-3625.
19. Miyazaki W, Tamaoka H, Shinohara M, et al. A complement inhibitor produced by Stachybotrys, sp K-76, a new species of fungi imperfecti. Microbiol Immunol 1980;24:1091-1108.
20. Sakamoto K, Tsujii E, Miyauchi M, et al. M FR901459, a novel immunosuppressant isolated from Stachybotrys chartarum (atra) No. 19392. J Antibiot (Tokyo) 1993;46:1788-1798.
21. Vesper SJ, Dearborn DG, Elidemir O, et al. Quantification of siderophore and hemolysis from Stachybotrys chartarum strains, including a strain isolated from the lung of a child with pulmonary hemorrhage and hemosiderosis. Appl Environ Microbiol 2000;66:2678-2681.
22. Vesper SJ, Magnuson ML, Dearborn DG, et al. Initial characterization of the hemolysin, stachylysin, from Stachybotrys chartarum. Infect Immun 2001;69:912-916.
23. Kordula T, Banbula A, Macomson J, et al. Isolation and properties of Stachyrase A, a chymotrypsin-like serine proteinase from Stachybotrys chartarum. Infect lmmun 2002;70:419-421.
24. Yike I, Rand T, Dearborn D. The role of fungal proteinases in pathophysiology of Stachybotrys chartarum. Mycopathologica 2007;164:in press.
25. Pestka JJ, Bondy GS. Mycotoxin-induced immune modulation. In: Dean JH, Luster MI, Munson AE, et al, eds. Immunotoxi-cology and immunopharmacology. New York: Raven Press Ltd, 1994;163-181.
26. West JB, Mathieu-Costello O. Structure, strength, failure, and remodeling of the pulmonary blood-gas barrier. Annu Rev Physiol 1999;61:543-572.