메뉴 건너뛰기




Volumn 71, Issue 7, 2007, Pages 1636-1643

Cellular absorption of anthraquinones emodin and chrysophanol in human intestinal Caco-2 cells

Author keywords

Caco 2 cell; Chrysophanol; Emodin; Intestinal absorption

Indexed keywords

ABSORPTION; CELLS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTEINS;

EID: 34548431270     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.70025     Document Type: Article
Times cited : (38)

References (25)
  • 1
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
    • Manach, C., Williamson, G., Morand, C., Scalbert, A., and Remesy, C., Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am. J. Clini. Nutr., 81, 230S-242S (2005).
    • (2005) Am. J. Clini. Nutr , vol.81
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4    Remesy, C.5
  • 2
    • 0036170655 scopus 로고    scopus 로고
    • Polyphenols from alcoholic apple cider are absorbed, metabolized and excreted by humans
    • DuPont, M. S., Bennett, R. N., Mellon, F. A., and Williamson, G., Polyphenols from alcoholic apple cider are absorbed, metabolized and excreted by humans. J. Nutr., 132, 172-175 (2002).
    • (2002) J. Nutr , vol.132 , pp. 172-175
    • DuPont, M.S.1    Bennett, R.N.2    Mellon, F.A.3    Williamson, G.4
  • 3
    • 0033051240 scopus 로고    scopus 로고
    • Occurrence of emodin, chrysophanol and physcion in vegetables, herbs and liquors. Genotoxicity and anti-genotoxicity of the anthraquinones and of the whole plants
    • Mueller, S. O., Schmitt, M., Dekant, W., Stopper, H., Schlatter, J., Schreier, P., and Lutz, W. K., Occurrence of emodin, chrysophanol and physcion in vegetables, herbs and liquors. Genotoxicity and anti-genotoxicity of the anthraquinones and of the whole plants. Food Chem. Toxicol., 37, 481-491 (1999).
    • (1999) Food Chem. Toxicol , vol.37 , pp. 481-491
    • Mueller, S.O.1    Schmitt, M.2    Dekant, W.3    Stopper, H.4    Schlatter, J.5    Schreier, P.6    Lutz, W.K.7
  • 4
    • 0028670941 scopus 로고
    • Role of cytochrome P-450 isoenzymes in the bioactivation of hydroxy anthraquinones
    • Fratta, D., Simi, S., Rainaldi, G., and Gervasi, P. G., Role of cytochrome P-450 isoenzymes in the bioactivation of hydroxy anthraquinones. Anticancer Res., 14, 2597-2603 (1994).
    • (1994) Anticancer Res , vol.14 , pp. 2597-2603
    • Fratta, D.1    Simi, S.2    Rainaldi, G.3    Gervasi, P.G.4
  • 5
    • 0034868937 scopus 로고    scopus 로고
    • Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5
    • Wang, H. W., Chen, T. L., Yang, P. C., and Ueng, T. H., Induction of cytochromes P450 1A1 and 1B1 by emodin in human lung adenocarcinoma cell line CL5. Drug Metab. Dispos., 29, 1229-1235 (2001).
    • (2001) Drug Metab. Dispos , vol.29 , pp. 1229-1235
    • Wang, H.W.1    Chen, T.L.2    Yang, P.C.3    Ueng, T.H.4
  • 6
    • 0031793967 scopus 로고    scopus 로고
    • Biotransformation of the anthraquinones emodin and chrysophanol by cytochrome P450 enzymes, bioactivation to genotoxic metabolites
    • Mueller, S. O., Stopper, H., and Dekan, W., Biotransformation of the anthraquinones emodin and chrysophanol by cytochrome P450 enzymes, bioactivation to genotoxic metabolites. Drug Metab. Dispos., 26, 540-546 (1998).
    • (1998) Drug Metab. Dispos , vol.26 , pp. 540-546
    • Mueller, S.O.1    Stopper, H.2    Dekan, W.3
  • 7
    • 0029150484 scopus 로고
    • Emodin pharmacokinetics in rabbits
    • Liang, J. W., Hsiu, S. L., Wu, P. P., and Chao, P. D., Emodin pharmacokinetics in rabbits. Planta Med., 61, 406-408 (1995).
    • (1995) Planta Med , vol.61 , pp. 406-408
    • Liang, J.W.1    Hsiu, S.L.2    Wu, P.P.3    Chao, P.D.4
  • 8
    • 2942609256 scopus 로고    scopus 로고
    • Inhibitory effect of emodin on tumor invasion through suppression of activator protein-1 and nuclear factor-kappaB
    • Huang, Q., Shen, H. M., and Ong, C. N., Inhibitory effect of emodin on tumor invasion through suppression of activator protein-1 and nuclear factor-kappaB. Biochem. Pharmacol., 68, 361-371 (2004).
    • (2004) Biochem. Pharmacol , vol.68 , pp. 361-371
    • Huang, Q.1    Shen, H.M.2    Ong, C.N.3
  • 9
    • 0035046141 scopus 로고    scopus 로고
    • In vitro antiviral activity of the anthraquinone chrysophanic acid against poliovirus
    • Semple, S. J., Pyke, S. M., Reynolds, G. D., and Flower, R. L., In vitro antiviral activity of the anthraquinone chrysophanic acid against poliovirus. Antiviral Res., 49, 169-178 (2001).
    • (2001) Antiviral Res , vol.49 , pp. 169-178
    • Semple, S.J.1    Pyke, S.M.2    Reynolds, G.D.3    Flower, R.L.4
  • 10
    • 34249830912 scopus 로고
    • Pharmacokinetics and bioavailability of madder anthraquinones - an investigation by HPLC
    • Krau, C., and Hesse, A., Pharmacokinetics and bioavailability of madder anthraquinones - an investigation by HPLC. Anal. Bioanal. Chem., 343, 111-112 (1992).
    • (1992) Anal. Bioanal. Chem , vol.343 , pp. 111-112
    • Krau, C.1    Hesse, A.2
  • 11
    • 0033943744 scopus 로고    scopus 로고
    • Metabolism of rhaponticin and chrysophanol 8-o-beta-D-glucopyranoside from the rhizome of Rheum undulatum by human intestinal bacteria and their anti-allergic actions
    • Kim, D. H., Park, E. K., Bae, E. A., and Han, M. J., Metabolism of rhaponticin and chrysophanol 8-o-beta-D-glucopyranoside from the rhizome of Rheum undulatum by human intestinal bacteria and their anti-allergic actions. Biol. Pharm. Bull., 23, 830-833 (2000).
    • (2000) Biol. Pharm. Bull , vol.23 , pp. 830-833
    • Kim, D.H.1    Park, E.K.2    Bae, E.A.3    Han, M.J.4
  • 12
    • 13544251603 scopus 로고    scopus 로고
    • Efflux of sphingoid bases by P-Glycoprotein in human intestinal Caco-2 cells
    • Sugawara, T., Kinoshita, M., and Saito, M., Efflux of sphingoid bases by P-Glycoprotein in human intestinal Caco-2 cells. Biosci. Biotechnol. Biochem., 68, 2541-2546 (2004).
    • (2004) Biosci. Biotechnol. Biochem , vol.68 , pp. 2541-2546
    • Sugawara, T.1    Kinoshita, M.2    Saito, M.3
  • 13
    • 18844425527 scopus 로고    scopus 로고
    • Involvement of P-glycoprotein in regulating cellular levels of Ginkgo flavonols: Quercetin, kaempferol, and isorhamnetin
    • Wang, Y., Cao, J., and Zeng, S., Involvement of P-glycoprotein in regulating cellular levels of Ginkgo flavonols: quercetin, kaempferol, and isorhamnetin. J. Pharm. Pharmacol., 57, 751-758 (2005).
    • (2005) J. Pharm. Pharmacol , vol.57 , pp. 751-758
    • Wang, Y.1    Cao, J.2    Zeng, S.3
  • 15
    • 3142549141 scopus 로고    scopus 로고
    • Quercetin glucosides inhibit glucose uptake into brush-border-membrane vesicles of porcine jejunum
    • Cermak, R., Landgraf, S., and Wolffram, S., Quercetin glucosides inhibit glucose uptake into brush-border-membrane vesicles of porcine jejunum. Br. J. Nutr., 91, 849-855 (2004).
    • (2004) Br. J. Nutr , vol.91 , pp. 849-855
    • Cermak, R.1    Landgraf, S.2    Wolffram, S.3
  • 16
    • 25844449050 scopus 로고    scopus 로고
    • Transepithelial permeability of myricitrin and its degradation by simulated digestion in human intestinal Caco-2 cell monolayer
    • Yokomizo, A., and Moriwaki, M., Transepithelial permeability of myricitrin and its degradation by simulated digestion in human intestinal Caco-2 cell monolayer. Biosci. Biotechnol. Biochem., 69, 1774-1776 (2005).
    • (2005) Biosci. Biotechnol. Biochem , vol.69 , pp. 1774-1776
    • Yokomizo, A.1    Moriwaki, M.2
  • 17
    • 0024593744 scopus 로고
    • Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability
    • Hidalgo, I. J., Raub, T. J., and Borchardt, R. T., Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology, 96, 736-749 (1989).
    • (1989) Gastroenterology , vol.96 , pp. 736-749
    • Hidalgo, I.J.1    Raub, T.J.2    Borchardt, R.T.3
  • 18
    • 0036201358 scopus 로고    scopus 로고
    • Absorption and metabolism of flavonoids in the Caco-2 cell culture model and a perfused rat intestinal model
    • Liu, Y., and Hu, M., Absorption and metabolism of flavonoids in the Caco-2 cell culture model and a perfused rat intestinal model. Drug Metab. Dispos., 30, 370-377 (2002).
    • (2002) Drug Metab. Dispos , vol.30 , pp. 370-377
    • Liu, Y.1    Hu, M.2
  • 19
    • 0142241274 scopus 로고    scopus 로고
    • Cellular uptake and efflux of the tea flavonoid (-)-epicatechin-3-gallate in the human intestinal cell line Caco-2
    • Vaidyanathan, J., and Walle, T., Cellular uptake and efflux of the tea flavonoid (-)-epicatechin-3-gallate in the human intestinal cell line Caco-2. The Journal of Pharmacology and Experimental Therapeutics., 307, 745-752 (2003).
    • (2003) The Journal of Pharmacology and Experimental Therapeutics , vol.307 , pp. 745-752
    • Vaidyanathan, J.1    Walle, T.2
  • 20
    • 14844303448 scopus 로고    scopus 로고
    • Dietary polyphenols decrease glucose uptake by human intestinal Caco-2 cells
    • Johnston, K., Sharp, P., Clifford, M., and Morgan, L., Dietary polyphenols decrease glucose uptake by human intestinal Caco-2 cells. FEBS Lett., 579, 1653-1657 (2005).
    • (2005) FEBS Lett , vol.579 , pp. 1653-1657
    • Johnston, K.1    Sharp, P.2    Clifford, M.3    Morgan, L.4
  • 21
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254 (1976).
    • (1976) Anal. Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 22
    • 0020265136 scopus 로고
    • Phlorizin as a probe of the small-intestinal Na1, D-glucose cotransporter. A model
    • Toggenburger, G., Kessler, M., and Semenza, G., Phlorizin as a probe of the small-intestinal Na1, D-glucose cotransporter. A model. Biochim. Biophys. Acta, 688, 557-571 (1982).
    • (1982) Biochim. Biophys. Acta , vol.688 , pp. 557-571
    • Toggenburger, G.1    Kessler, M.2    Semenza, G.3
  • 23
    • 0036228345 scopus 로고    scopus 로고
    • Inverse association of tea and flavonoid intakes with incident myocardial infarction: The Rotterdam Study
    • Geleijnse, J. M., Launer, L. J., Van, D. A., Hofman, A., and Witteman, J. C., Inverse association of tea and flavonoid intakes with incident myocardial infarction: the Rotterdam Study. Am. J. Clin. Nutr., 75, 880-886 (2002).
    • (2002) Am. J. Clin. Nutr , vol.75 , pp. 880-886
    • Geleijnse, J.M.1    Launer, L.J.2    Van, D.A.3    Hofman, A.4    Witteman, J.C.5
  • 25
    • 22144448888 scopus 로고    scopus 로고
    • The role of drug metabolizing enzymes in the effect and side-effect of the drugs
    • Vereczkey, L., Jemnitz, K., Monostory, K., Veres, Z., and Kobori, L., The role of drug metabolizing enzymes in the effect and side-effect of the drugs. Orv. Hetil., 146, 947-952 (2005).
    • (2005) Orv. Hetil , vol.146 , pp. 947-952
    • Vereczkey, L.1    Jemnitz, K.2    Monostory, K.3    Veres, Z.4    Kobori, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.