Mycophenolic acid (MPA) and its glucuronide metabolites interact with transport systems responsible for excretion of organic anions in the basolateral membrane of the human kidney

Nephrology Dialysis Transplantation

Volumn 22, Issue 9, 2007, Pages 2497-2503

  Wolff, Natascha A ^a,b   Burckhardt, Birgitta C ^a   Burckhardt, Gerhard ^a   Oellerich, Michael ^a   Armstrong, Victor W ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF WITTEN HERDECKE   (Germany)

Author keywords

Glucuronide mycophenolate metabolites; HNaDC3; HOAT1 3; Kidney; Mycophenolic acid; Transport

Indexed keywords

4 AMINOHIPPURIC ACID; ANION; ANTIVIRUS AGENT; COMPLEMENTARY RNA; DICARBOXYLATE TRANSPORTER; DRUG METABOLITE; ESTRONE SULFATE; GLUCURONIDE; HYDROCORTISONE; MYCOPHENOLIC ACID; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 3; SUCCINIC ACID; TRITIUM;

ANIMAL CELL; ARTICLE; BASOLATERAL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ELIMINATION; DRUG MECHANISM; DRUG STRUCTURE; IN VITRO STUDY; ION CURRENT; KIDNEY CELL; KIDNEY TUBULE ABSORPTION; MOLECULAR INTERACTION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SYNTHESIS; URINARY EXCRETION; XENOPUS LAEVIS;

ANIMALS; BIOLOGICAL TRANSPORT; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCURONIDES; HUMANS; KIDNEY; KINETICS; MEMBRANES; MYCOPHENOLIC ACID; ORGANIC ANION TRANSPORT PROTEIN 1; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; SUCCINIC ACID; XENOPUS;

EID: 34548414188     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfm219     Document Type: Article

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