The biological predisposition to obesity: Beyond the thrifty genotype scenario

International Journal of Obesity

Volumn 31, Issue 9, 2007, Pages 1337-1339

  Bouchard, C ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOGENESIS; DEVELOPING COUNTRY; DISEASE PREDISPOSITION; DNA SEQUENCE; FOOD INTAKE; GENOTYPE; HUMAN; LIPID OXIDATION; NOTE; OBESITY; PRIORITY JOURNAL; SOCIAL ENVIRONMENT; WEIGHT GAIN;

ENERGY INTAKE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; OBESITY; RISK REDUCTION BEHAVIOR;

EID: 34548358843     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/sj.ijo.0803610     Document Type: Note

References (8)

1. Bouchard C, Tremblay A, Despres J-P, Nadeau A, Lupien PJ, Theriault G et al. The response to long-term overfeeding in identical twins. N Engl J Med 1990; 322: 1477-1482.
2. Bouchard C, Tremblay A, Despres J-P, Theriault G, Nadeau A, Lupien PJ et al. The response to exercise with constant energy intake in identical twins. Obes Res 1994; 2: 400-410.
3. Hainer V, Stunkard AJ, Kunesova M, Parizkova J, Stich V, Allison DB. Intrapair resemblance in very low calorie diet-induced weight loss in female obese identical twins. Int J Obes Relat Metab Disord 2000; 24: 1051-1057.
4. Neel J. Diabetes mellitus: a 'thrifty' genotype rendered detrimental by 'progress'? Am J Hum Genet 1962; 14: 353-362.
5. Neel JV. The 'thrifty genotype' in 1998. Nut Rev 1999; 57: S2-S9.
6. Speakman JR. Thrifty genes for obesity and the metabolic syndrome - time to call off the search? Diab Vasc Dis Res 2006; 3: 7-11.
7. Rankinen T, Zuberi A, Chagnon YC, Weisnagel SJ, Argyropoulos G, Walts B et al. The human obesity gene map: the 2005 update. Obesity (Silver.Spring) 2006; 14: 529-644.
8. Bouchard C, Rankinen T. Exciting advances and new opportunities. In: Clement K, Sorensen TIA (eds). Genomics of Obesity. Taylor and Francis Group, LLC: New York, in press.