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Volumn 39, Issue 1-2, 2007, Pages 1-8

The two most common alleles of the coding GGN repeat in the androgen receptor gene cause differences in protein function

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ASPARAGINE; GLYCINE; GUANINE;

EID: 34548329696     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/JME-06-0072     Document Type: Article
Times cited : (31)

References (37)
  • 1
    • 34548318437 scopus 로고    scopus 로고
    • Partial androgen insensitivity syndrome (AIS) in patients with a normal androgen receptor (AR) gene seqeunce is possibly caused by an activated but abnormally working AR
    • Québec City, Canada. Abstract 86
    • Alléra A, Wolff M, Watzka M, Daufeldt S, Sinnecker G & Bidlingmaier F 1998 Partial androgen insensitivity syndrome (AIS) in patients with a normal androgen receptor (AR) gene seqeunce is possibly caused by an activated but abnormally working AR. 10th International Congress on Hormonal Steroids, Québec City, Canada. Abstract 86.
    • (1998) 10th International Congress on Hormonal Steroids
    • Alléra, A.1    Wolff, M.2    Watzka, M.3    Daufeldt, S.4    Sinnecker, G.5    Bidlingmaier, F.6
  • 5
    • 0028033594 scopus 로고
    • The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function
    • Chamberlain NL, Driver ED & Miesfeld RL 1994 The length and location of CAG trinucleotide repeats in the androgen receptor N-terminal domain affect transactivation function. Nucleic Acids Research 22 3181-3186.
    • (1994) Nucleic Acids Research , vol.22 , pp. 3181-3186
    • Chamberlain, N.L.1    Driver, E.D.2    Miesfeld, R.L.3
  • 8
    • 33750542952 scopus 로고    scopus 로고
    • A comprehensive analysis of the androgen receptor gene and risk of breast cancer: Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    • Cox DG, Blanche H, Pearce CL, Calle EE, Colditz GA, Pike MC, Albanes D, Allen NE, Amiano P, Berglund G et al. 2006 A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3). Breast Cancer Research 8 R54.
    • (2006) Breast Cancer Research , vol.8
    • Cox, D.G.1    Blanche, H.2    Pearce, C.L.3    Calle, E.E.4    Colditz, G.A.5    Pike, M.C.6    Albanes, D.7    Allen, N.E.8    Amiano, P.9    Berglund, G.10
  • 9
    • 11844283413 scopus 로고    scopus 로고
    • Effect of GGC (glycine) repeat length polymorphism in the human androgen receptor on androgen action
    • Ding D, Xu L, Menon M, Reddy GP & Barrack ER 2005 Effect of GGC (glycine) repeat length polymorphism in the human androgen receptor on androgen action. Prostate 62 133-139.
    • (2005) Prostate , vol.62 , pp. 133-139
    • Ding, D.1    Xu, L.2    Menon, M.3    Reddy, G.P.4    Barrack, E.R.5
  • 12
    • 0035094402 scopus 로고    scopus 로고
    • Polymorphism of the androgen receptor gene is associated with male pattern baldness
    • Ellis JA, Stebbing M & Harrap SB 2001 Polymorphism of the androgen receptor gene is associated with male pattern baldness. Journal of Investigative Dermatology 116 452-455.
    • (2001) Journal of Investigative Dermatology , vol.116 , pp. 452-455
    • Ellis, J.A.1    Stebbing, M.2    Harrap, S.B.3
  • 16
    • 0034665359 scopus 로고    scopus 로고
    • Polymorphic CAG and GGN repeat lengths in the androgen receptor gene and prostate cancer risk: A population-based case-control study in China
    • Hsing AW, Gao YT, Wu G, Wang X, Deng J, Chen YL, Sesterhenn IA, Mostofi FK, Benichou J & Chang C 2000 Polymorphic CAG and GGN repeat lengths in the androgen receptor gene and prostate cancer risk: a population-based case-control study in China. Cancer Research 60 5111-5116.
    • (2000) Cancer Research , vol.60 , pp. 5111-5116
    • Hsing, A.W.1    Gao, Y.T.2    Wu, G.3    Wang, X.4    Deng, J.5    Chen, Y.L.6    Sesterhenn, I.A.7    Mostofi, F.K.8    Benichou, J.9    Chang, C.10
  • 18
    • 0028922314 scopus 로고
    • Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: Possible pathogenetic relevance for the (CAG) n-expanded neuronopathies
    • Kazemi-Esfarjani P, Trifiro, MA & Pinsky L 1995 Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: possible pathogenetic relevance for the (CAG) n-expanded neuronopathies. Human Molecular Genetics 4 523-527.
    • (1995) Human Molecular Genetics , vol.4 , pp. 523-527
    • Kazemi-Esfarjani, P.1    Trifiro, M.A.2    Pinsky, L.3
  • 19
    • 0034804086 scopus 로고    scopus 로고
    • Extent of linkage disequilibrium between the androgen receptor gene CAG and GGC repeats in human populations: Implications for prostate cancer risk
    • Kittles RA, Young D, Weinrich S, Hudson J, Argyropoulos G, Ukoli F, Adams-Campbell L & Dunston GM 2001 Extent of linkage disequilibrium between the androgen receptor gene CAG and GGC repeats in human populations: implications for prostate cancer risk. Human Genetics 109 253-261.
    • (2001) Human Genetics , vol.109 , pp. 253-261
    • Kittles, R.A.1    Young, D.2    Weinrich, S.3    Hudson, J.4    Argyropoulos, G.5    Ukoli, F.6    Adams-Campbell, L.7    Dunston, G.M.8
  • 20
    • 0029805706 scopus 로고    scopus 로고
    • The new genomics: Global views of biology
    • Lander ES 1996 The new genomics: global views of biology. Science 274 536-539.
    • (1996) Science , vol.274 , pp. 536-539
    • Lander, E.S.1
  • 22
    • 0031441453 scopus 로고    scopus 로고
    • Codon-usage variants in the polymorphic (GGN) n trinucleotide repeat of the human androgen receptor gene
    • Lumbroso R, Beitel LK, Vasiliou DM, Trifiro MA & Pinsky L 1997 Codon-usage variants in the polymorphic (GGN) n trinucleotide repeat of the human androgen receptor gene. Human Genetics 101 43-46.
    • (1997) Human Genetics , vol.101 , pp. 43-46
    • Lumbroso, R.1    Beitel, L.K.2    Vasiliou, D.M.3    Trifiro, M.A.4    Pinsky, L.5
  • 27
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD & Polesky HF 1988 A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Research 16 1215.
    • (1988) Nucleic Acids Research , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 29
    • 0036799545 scopus 로고    scopus 로고
    • The allelic architecture of human disease genes: Common disease-common variant... or not?
    • Pritchard JK & Cox NJ 2002 The allelic architecture of human disease genes: common disease-common variant... or not? Human Molecular Genetics 11 2417-2423.
    • (2002) Human Molecular Genetics , vol.11 , pp. 2417-2423
    • Pritchard, J.K.1    Cox, N.J.2
  • 31
    • 4544297967 scopus 로고    scopus 로고
    • Androgen receptor gene GGN and CAG polymorphisms among severely oligozoospermic and azoospermic Swedish men
    • Ruhayel Y, Lundin K, Giwercman Y, Hallden C, Willen M & Giwercman A 2004 Androgen receptor gene GGN and CAG polymorphisms among severely oligozoospermic and azoospermic Swedish men. Human Reproduction 19 2076-2083.
    • (2004) Human Reproduction , vol.19 , pp. 2076-2083
    • Ruhayel, Y.1    Lundin, K.2    Giwercman, Y.3    Hallden, C.4    Willen, M.5    Giwercman, A.6
  • 32
    • 0004136246 scopus 로고    scopus 로고
    • 3rd edn, pp, Ed J Argentine. Cold Spring Harbor: Cold Spring Harbor Laboratory Press
    • Sambrook J & Russel DW 2001 In Molecular Cloning: a Laboratory Manual, 3rd edn, pp A8.40-A8.45. Ed J Argentine. Cold Spring Harbor: Cold Spring Harbor Laboratory Press.
    • (2001) Molecular Cloning: A Laboratory Manual
    • Sambrook, J.1    Russel, D.W.2
  • 34
    • 12244251383 scopus 로고    scopus 로고
    • Androgen receptor (CAG) n and (GGC) n polymorphisms and breast cancer risk in a population-based case-control study of young women
    • Suter NM, Malone KE, Daling JR, Doody DR & Ostrander EA 2003 Androgen receptor (CAG) n and (GGC) n polymorphisms and breast cancer risk in a population-based case-control study of young women. Cancer Epidemiology, Biomarkers and Prevention 12 127-135.
    • (2003) Cancer Epidemiology, Biomarkers and Prevention , vol.12 , pp. 127-135
    • Suter, N.M.1    Malone, K.E.2    Daling, J.R.3    Doody, D.R.4    Ostrander, E.A.5
  • 35
    • 2342429982 scopus 로고    scopus 로고
    • Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells
    • Wang Q, Udayakumar TS, Vasaitis TS, Brodie AM & Fondell JD 2004 Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells. Journal of Biological Chemistry 279 17319-17328.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 17319-17328
    • Wang, Q.1    Udayakumar, T.S.2    Vasaitis, T.S.3    Brodie, A.M.4    Fondell, J.D.5
  • 36
    • 33748752321 scopus 로고    scopus 로고
    • The A645D mutation in the hinge region of the human androgen receptor (AR) gene modulates AR activity, depending on the context of the polymorphic glutamine and glycine repeats
    • Werner R, Holterhus PM, Binder G, Schwarz HP, Morlot M, Struve D, Marschke C & Hiort O 2006 The A645D mutation in the hinge region of the human androgen receptor (AR) gene modulates AR activity, depending on the context of the polymorphic glutamine and glycine repeats. Journal of Clinical Endocrinology and Metabolism 91 3515-3520.
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , pp. 3515-3520
    • Werner, R.1    Holterhus, P.M.2    Binder, G.3    Schwarz, H.P.4    Morlot, M.5    Struve, D.6    Marschke, C.7    Hiort, O.8
  • 37
    • 8344242217 scopus 로고    scopus 로고
    • How strong is the association between CAG and GGN repeat length polymorphisms in the androgen receptor gene and prostate cancer risk?
    • Zeegers MP, Kiemeney LA, Nieder AM & Ostrer H 2004 How strong is the association between CAG and GGN repeat length polymorphisms in the androgen receptor gene and prostate cancer risk? Cancer Epidemiology, Biomarkers and Prevention 13 1765-1771.
    • (2004) Cancer Epidemiology, Biomarkers and Prevention , vol.13 , pp. 1765-1771
    • Zeegers, M.P.1    Kiemeney, L.A.2    Nieder, A.M.3    Ostrer, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.