Melanocytic nevi simulant of melanoma with medicolegal relevance

Virchows Archiv

Volumn 451, Issue 3, 2007, Pages 623-647

  Massi, Guido ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Medicolegal lawsuit; Melanocytic nevi; Melanoma; Simulators

Indexed keywords

ACRAL LENTIGINOUS MELANOMA; ACRAL LENTIGINOUS NEVUS; BLUE NEVUS; CELLULAR BLUE NEVUS; CONGENITAL NEVUS; DEEP PENETRATING NEVUS; DESMOPLASTIC MELANOMA; DESMOPLASTIC NEVUS; EPITHELIOID BLUE NEVUS; EPITHELIOID CELL; HUMAN; IMMUNOHISTOCHEMISTRY; JUVENILE MELANOMA; MEDICOLEGAL ASPECT; MELANOCYTIC NEVUS; MELANOMA; NEVOID MELANOMA; NEVUS; PRIORITY JOURNAL; REED NEVUS; REGRESSING MELANOMA; REGRESSING NEVUS; REVIEW; SPINDLE CELL MELANOMA; SPINDLE CELL NEVUS; SPITZOID MELANOMA;

ADULT; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; DYSPLASTIC NEVUS SYNDROME; HUMANS; INFANT; INFANT, NEWBORN; LIABILITY, LEGAL; MELANOMA; NEOPLASMS, SECOND PRIMARY; NEVUS; NEVUS, BLUE; NEVUS, PIGMENTED; NEVUS, SPINDLE CELL; PATHOLOGY; SKIN NEOPLASMS;

EID: 34548324530     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-007-0459-7     Document Type: Review

References (161)

1. Ackerman AB, Kornberg R (1975) Pseudomelanoma: recurrent melanocytic nevus following partial surgical removal. Arch Dermatol 111:1588-1589
2. Ackerman AB, Magana-Garcia M (1990) Naming acquired melanocytic nevi. Unna's Miescher's, Spitz's, Clark's. Am J Dermatopathol 12:193-209
3. Ackerman AB, Milde P (1992) Naming acquired melanocytic nevi. Common and dysplastic, normal and atypical, or Unna, Miescher, Spitz, and Clark? Am J Dermatopathol 14:447-453
4. Akiyama M, Inamoto N, Kuramochi S, Nakamura K (1997) Spitz naevus with a predominant epithelioid cell component and halo reaction. Histopathology 31:292-293
5. Angelucci D, Natali PG, Amerio PL, Ramenghi M, Musiani P (1991) Rapid perinatal growth mimicking malignant transformation in a giant congenital melanocytic nevus. Human Pathol 22:297-301
6. Antony FC, Sanclemente G, Shaikh H, Trelles AS, Calonje E (2006) Pigment synthesizing melanoma (so-called animal type melanoma): a clinicopathological study of 14 cases of a poorly known distinctive variant of melanoma. Histopathology 48:754-762
7. Ball NJ, Golitz LE (1994) Melanocytic nevi with focal atypical epithelioid cell components: a review of seventy-three cases. J Am Acad Dermatol 30:724-729
8. Barnhill RL, Barnhill MA, Berwick M, Mihm MC Jr (1991) The histologic spectrum of pigmented spindle cell nevus: a review of 120 cases with emphasis on atypical variants. Human Pathol 22:52-58
9. Barnhill RL, Mihm MC Jr, Magro CM (1991) Plexiform spindle cell naevus: a distinctive variant of plexiform melanocytic naevus. Histopathology 18:243-247
10. Barnhill RL, Flotte TJ, Fleischli M, Perez-Atayde A (1995) Cutaneous melanoma and atypical Spitz tumors in childhood. Cancer 76:1833-1845
11. Barnhill RL, Argenyi ZB, From L, Glass LF, Maize JC, Mihm MC Jr, Rabkin MS, Ronan SG, White WL, Piepkorn M (1999) Atypical Spitz nevi/tumors: lack of consensus for diagnosis, discrimination from melanoma, and prediction of outcome. Human Pathol 30:513-520
12. Barnhill RL, Piepkorn M, Busam KJ (2004) Pathology of Melanocytic nevi and malignant melanoma. Springer, New York, pp 160-171
13. Barnhill RL (2006) The Spitzoid lesion: rethinking Spitz tumors, atypical variants, 'Spitzoid melanoma' and risk assessment. Mod Path 19:S21-S33
14. Barnhill RL (2006) The spitzoid lesion: the importance of atypical variants and risk assessment. Am J Dermatopathol 28:75-83
15. Barr RJ, Linden KG, Rubinstein G, Cantos KA (2003) Analysis of heterogeneity of atypia within melanocytic nevi. Arch Dermatol 139:289-292
16. Bastian BC, Xiong J, Frieden IJ, Williams ML, Chou P, Busam K, Pinkel D, LeBoit PE (2002) Genetic changes in neoplasms arising in congenital melanocytic nevi: differences between nodular proliferations and melanomas. Am J Pathol 161:1163-1169
17. Bergman R, Malkin L, Sabo E, Kerner H (2001) MIB-1 monoclonal antibody to determine proliferative activity of Ki-67 antigen as an adjunct to the histopathologic differential diagnosis of Spitz nevi. J Am Acad Dermatol 44:500-504
18. Bevona C, Tannous Z, Tsao H (2003) Dermal melanocytic proliferation with features of a plaque-type blue nevus and neurocristic hamartoma. J Am Acad Dermatol 49:924-929
19. Bhawan J, Cao SL (1999) Amelanotic blue nevus: a variant of blue nevus. Am J Dermatopathol 21:225-228
20. Blessing K, McLaren KM (1992) Histological regression in primary cutaneous melanoma: recognition, prevalence and significance. Histopathology 20:315-322
21. Borbujo J, Jara M, Cortes L, Sanchez de Leon L (2000) A newborn with nodular ulcerated lesion on a giant congenital nevus. Pediatr Dermatol 17:299-301
22. Boyd AS, Rapini RP (1994) Acral melanocytic neoplasms: a histologic analysis of 158 lesions. J Am Acad Dermatol 31:740-745
23. Braun-Falco M, Friedrichson E, Ring J (2005) Subepidermal cleft formation as a diagnostic marker for cutaneous malignant melanoma. Human Pathol 36:412-415
24. Bruijn JA, Mihm MC Jr, Barnhill RL (1992) Desmoplastic melanoma. Histopathology 20:197-205
25. Busam KJ (1999) Metastatic melanoma to the skin simulating blue nevus. Am J Surg Pathol 23:276-282
26. Busam KJ, Woodruff JM, Erlandson RA, Brady MS (2000) Large plaque-type blue nevus with subcutaneous cellular nodules. Am J Surg Pathol 24:92-99
27. Cassarino DS, Fullen DR, Sondak VK, Duray PH (2003) Metastatic nevoid melanoma in a 4 1/2-year-old child. J Cutan Pathol 30:647-651
28. Celleno L, Massi G (2002) A variant of junctional naevus of epithelioid and spindle cell type rich in melanophages. Acta Derm-Venereol 82:456-459
29. Chan GS, Choy C, Ng WK, Chan KW (1999) Desmoplastic malignant melanoma on the buttock of an 18-year-old girl: differentiation from desmoplastic nevus. Am J Dermatopathol 21:170-173
30. Chorny JA, Barr RJ (2002) S100-positive spindle cells in scars: a diagnostic pitfall in the re-excision of desmoplastic melanoma. Am J Dermatopathol 24:309-312
31. Chorny JA, Barr RJ, Kyshtoobayeva A, Jakowatz J, Reed RJ (2003) Ki-67 and p53 expression in minimal deviation melanomas as compared with other nevomelanocytic lesions. Mod Path 16:525-529
32. Clark WH Jr, Hood AF, Tucker MA, Jampel RM (1998) Atypical melanocytic nevi of the genital type with a discussion of reciprocal parenchymal-stromal interactions in the biology of neoplasia. Human Pathol 29:S1-S24
33. Clemente C, Zurrida S, Bartoli C, Bono A, Collini P, Rilke F (1995) Acral-lentiginous naevus of plantar skin. Histopathology 27:549-555
34. Cook MG, Clarke TJ, Humphreys S, Fletcher A, McLaren KM, Smith NP, Stevens A, Theaker JM, Melia J (1996) The evaluation of diagnostic and prognostic criteria and the terminology of thin cutaneous malignant melanoma by the CRC Melanoma Pathology Panel. Histopathology 28:497-512
35. Cook MG (2004) Benign melanocytic lesions mimicking melanomas. Pathology 36:414-418
36. Cooper PH (1992) Deep penetrating (plexiform spindle cell) nevus. A frequent participant in combined nevus. J Cutan Pathol 19:172-180
37. Crowson AN, Magro CH, Clark WH (1996) Pilar neurocristic hamartoma. J Am Acad Dermatol 34:715
38. De Vooght A, Vanwijck R, Gosseye S, Bayet B (2003) Pseudo-tumoral proliferative nodule in a giant congenital naevus. Br J Plast Surg 56:164-167
39. Deyrup AT, Althof P, Zhou M, Morgan M, Solomon AR, Bridge JA, Weiss SW (2004) Paraganglioma-like dermal melanocytic tumor: a unique entity distinct from cellular blue nevus, clear cell sarcoma, and cutaneous melanoma. Am J Surg Pathol 28:1579-1586
40. Diaz-Cascajo C, Borghi S, Weyers W (2000) Angiomatoid Spitz nevus: a distinct variant of desmoplastic Spitz nevus with prominent vasculature. Am J Dermatopathol 22:135-139
41. Driscoll MS, Grant-Kels JM (2006) Nevi and melanoma in pregnancy. Dermatol Clin 24:199-204
42. Elder DE, Green MH, Guerry D 4th, Kraemer KH, Clark WH Jr (1982) The dysplastic nevus syndrome: our definition. Am J Dermatopathol 4:455-460
43. Elder DE (2006) Precursors to melanoma and their mimics: nevi of special sites. Mod Path 19:S4-S20
44. Fallowfield ME, Collina G, Cook MG (1994) Melanocytic lesions of the palm and sole. Histopathology 24:463-467
45. Farrahi F, Egbert BM, Swetter SM (2005) Histologic similarities between lentigo maligna and dysplastic nevus: importance of clinicopathologic distinction. J Cutan Pathol 32:405-412
46. Ferrara G, Crisman G, Soyer HP, Zalaudek I, Argenziano G (2006) Intraepidermal dendritic melanocytes in spitzoid neoplasms. Am J Dermatopathol 28:449-450
47. Flauta VS, Lingamfelter DC, Dang LM, Lankachandra KM (2006) Deep penetrating nevus: a case report and brief literature review. Diagn Pathol 25(1):31
48. Flax SH, Skelton HG, Smith KJ, Lupton GP (1998) Nodular melanosis due to epithelial neoplasms: a finding not restricted to regressed melanomas. Am J Dermatopathol 20:118-122
49. Gach JE, Carr RA, Charles-Holmes R, Harris S (2004) Multiple congenital melanocytic naevi presenting with neurofibroma-like lesions complicated by malignant melanoma. Clin Exp Dermatol 29:473-476
50. Goldenhersh MA, Savin RC, Barnhill RL, Stenn KS (1988) Malignant blue nevus. Case report and literature review. J Am Acad Dermatol 19:712-722
51. Gottlieb GJ, Ackerman AB (1985) Mitotic figures may be seen in cells of banal melanocytic nevi. Am J Dermatopathol 7:87-89
52. Granter SR, McKee PH, Calonje E, Mihm MC Jr, Busam K (2001) Melanoma associated with blue nevus and melanoma mimicking cellular blue nevus: a clinicopathologic study of 10 cases on the spectrum of so-called 'malignant blue nevus'. Am J Surg Pathol 25:316-323
53. Grin CM, Rojas AI, Grant-Kels JM (2001) Does pregnancy alter melanocytic nevi? J Cutan Pathol 28:389-392
54. Guitart J, Lowe L, Piepkorn M, Prieto VG, Rabkin MS, Ronan SG, Shea CR, Tron VA, White W, Barnhill RL (2002) Histological characteristics of metastasizing thin melanomas: a case-control study of 43 cases. Arch Dermatol 138:603-608
55. Hantschke M, Bastian BC, LeBoit PE (2004) Consumption of the epidermis: a diagnostic criterion for the differential diagnosis of melanoma and Spitz nevus. Am J Surg Pathol 28:1621-1625
56. Harris GR, Shea CR, Horenstein MG, Reed JA, Burchette JL Jr, Prieto VG (1999) Desmoplastic (sclerotic) nevus: an underrecognized entity that resembles dermatofibroma and desmoplastic melanoma. Am J Surg Pathol 23:786-794
57. Harvell JD, Meehan SA, LeBoit PE (1997) Spitz's nevi with halo reaction: a histopathologic study of 17 cases. J Cutan Pathol 24:611-619
58. Harvell JD, White WL (1999) Persistent and recurrent blue nevi. Am J Dermatopathol 21:506-517
59. Heenan PJ (2001) Pitfalls in the histopathologic diagnosis of malignant melanoma. Am J Dermatopathol 23:242
60. Herron MD, Vanderhooft SL, Smock K, Zhou H, Leachman SA, Coffin C (2004) Proliferative nodules in congenital melanocytic nevi: a clinicopathologic and immunohistochemical analysis. Am J Surg Pathol 28:1017-1025
61. High WA, Stewart D, Wilbers CR, Cockerell CJ, Hoang MP, Fitzpatrick JE (2005) Completely regressed primary cutaneous malignant melanoma with nodal and/or visceral metastases: a report of 5 cases and assessment of the literature and diagnostic criteria. J Am Acad Dermatol 53:89-100
62. Howard B, Ragsdale B, Lundquist K (2005) Pigmented epithelioid melanocytoma: two case reports. Dermatol Online J 11:1
63. Hussein MR (2005) Melanocytic dysplastic naevi occupy the middle ground between benign melanocytic naevi and cutaneous malignant melanomas: emerging clues. J Clin Pathol 58:453-456
64. Kapur P, Selim MA, Roy LC, Yegappan M, Weinberg AG, Hoang MP (2005) Spitz nevi and atypical Spitz nevi/tumors: a histologic and immunohistochemical analysis. Mod Pathol 18:197-204
65. Karamitopoulou-Diamantis E, Paredes B, Vajtai I (2006) Cutaneous neurocristic hamartoma with blue naevus-like features and plexiform dermal hyperneury. Histopathology 49:326-328
66. Kazakov DV, Rutten A, Kempf W, Michal M (2004) Melanoma with prominent pigment synthesis (animal-type melanoma): a case report with ultrastructural studies. Am J Dermatopathol 26:290-297
67. Kerl H, Soyer HP, Cerroni L, Wolf IH, Ackerman AB (1998) Ancient melanocytic nevus. Semin Diagn Pathol 15:210-215
68. Kim JC, Murphy GF (2000) Dysplastic melanocytic nevi and prognostically indeterminate nevomelanomatoid proliferations. Clin Lab Med 20:691-712
69. Kim YC, Lee MG, Choe SW, Lee MC, Chung HG, Cho SH (2003) Acral lentiginous melanoma: an immunohistochemical study of 20 cases. Int J Dermatol 42:123-129
70. King R, Page RN, Googe PB, Mihm MC Jr (2005) Lentiginous melanoma: a histologic pattern of melanoma to be distinguished from lentiginous nevus. Mod Pathol 18:1397-1401
71. Kiryu H, Imayama S (2001) Malignant melanoma cells in the eccrine apparatus. J Dermatol 28:91-94
72. Kornberg R, Ackerman AB (1975) Pseudomelanoma: recurrent melanocytic nevus following partial surgical removal. Arch Dermatol 111:1588-1590
73. Kossard S, Wilkinson B (1995) Nucleolar organizer regions and image analysis nuclear morphometry of small cell (nevoid) melanoma. J Cutan Pathol 22:132-136
74. Kossard S (2002) Atypical lentiginous junctional naevi of the elderly and melanoma. Australas J Dermatol 43:93-101
75. Kuchelmeister C, Schaumburg-Lever G, Garbe C (2000) Acral cutaneous melanoma in caucasians: clinical features, histopathology and prognosis in 112 patients. Br J Dermatol 143:275-280
76. Kuhn A, Groth W, Gartmann H, Steigleder GK (1988) Malignant blue nevus with metastases to the lung. Am J Dermatopathol 10:436-441
77. Kwon IH, Lee JH, Cho KH (2004) Acral lentiginous melanoma in situ: a study of nine cases. Am J Dermatopathol 26:285-289
78. Imber MJ (1990) Benign cutaneous lesions potentially misdiagnosed as malignant neoplasms. Semin Diagn Pathol 7:139-145
79. Lach B, Russell N, Benoit B, Atack D (1988) Cellular blue nevus ("melanocytoma") of the spinal meninges: electron microscopic and immunohistochemical features. Neurosurgery 22:773-780
80. LeBoit PE (1994) Malignant melanoma and melanocytic neoplasms. Pathology. Hanley and Belfus, Philadelphia, pp 231-232
81. LeBoit PE (2002) Melanosis and its meanings. Am J Dermatopathol 24:369-372
82. Leech SN, Bell H, Leonard N, Jones SL, Geurin D, McKee PH, Lawrence CM (2004) Neonatal giant congenital nevi with proliferative nodules: a clinicopathologic study and literature review of neonatal melanoma. Arch Dermatol 140:83-88
83. Longacre TA, Egbert BM, Rouse RV (1996) Desmoplastic and spindle-cell malignant melanoma. An immunohistochemical study. Am J Surg Pathol 20:1489-1500
84. MacKelfresh J, Chen SC, Monthrope YM (2005) Pregnancy and changes in melanocytic nevi. Obstet Gynecol 106:857-860
85. Mackie RM, Doherty VR (1992) The desmoplastic melanocytic naevus: a distinct histological entity. Histopathology 20:207-211
86. Magro CM, Crowson AN, Mihm MC (2006) Unusual variants of malignant melanoma. Mod Path 19:S41-S70
87. Maurichi A, Baldi M, Bartoli C, Bono A, Camerini T, Moglia D, Patuzzo R, Pennacchioli E, Tragni G, Santinami M (2004) Pigmented spindle-cell nevus: a melanoma simulator. Dermatol Online J 10:5
88. McGovern VJ, Cochran AJ, Van der Esch EP, Little JH, MacLennan R (1986) The classification of malignant melanoma, its histological reporting and registration: a revision of the 1972 Sydney classification. Pathology 18:12-21
89. McNutt NS, Urmacher C, Hakimian J, Hoss DM, Lugo J (1995) Nevoid malignant melanoma: morphologic patterns and immunohistochemical reactivity. J Cutan Pathol 22:502-517
90. McNutt NS (1998) "Triggered trap": nevoid malignant melanoma. Semin Diagn Pathol 15:203-209
91. Menzies SW, McCarthy WH (1997) Complete regression of primary cutaneous malignant melanoma. Arch Surg 132:553-556
92. Mezebish D, Smith K, Williams J, Menon P, Crittenden J, Skelton H (1998) Neurocristic cutaneous hamartoma: a distinctive dermal melanocytosis with an unknown malignant potential. Mod Pathol 11:573-578
93. Michal M, Kerekes Z, Kinkor Z, Ondrias F, Pizinger K (1995) Desmoplastic cellular blue nevi. Am J Dermatopathol 17:230-235
94. Michal M (1998) Cellular blue naevi with microalveolar pattern-a type of naevus frequently confused with melanoma. Pathol Res Pract 194:83-86
95. Miura K, Harada H, Tsutsui Y (1999) Small cell type malignant melanoma which developed in a 16-year-old female with a congenital dermal nevus and metastasized 12 years after excision. Pathol Int 49:247-252
96. Mones JM, Ackerman AB (2004) "Atypical" Spitz's nevus, "malignant" Spitz's nevus, and "metastasizing" Spitz's nevus: a critique in historical perspective of three concepts flawed fatally. Am J Dermatopathol 26:310-333
97. Mones JM, Ackerman AB (2004) "Atypical" blue nevus, "malignant" blue nevus, and "metastasizing" blue nevus: a critique in historical perspective of three concepts flawed fatally. Am J Dermatopathol 26:407-430
98. Mooney MA, Barr RJ, Buxton MG (1995) Halo nevus or halo phenomenon? A study of 142 cases. J Cutan Pathol 22:342-348
99. Ng SH, Chave TA (2006) Tumoral melanosis as a manifestation of a completely regressed primary melanoma with metastases. Br J Dermatol 155:627-628
100. Okamura JM, Barr RJ, Cantos KA (2000) Benign atypical junctional melanocytic hyperplasia associated with intradermal nevi: a common finding that may be confused with melanoma in situ. Mod Pathol 13:857-860
101. Paredes B, Hardmeier T (1998) [Spitz nevus and Reed nevus: simulating melanoma in adults]. Pathologe 19:401-403
102. Pathy AL, Helm TN, Elston D, Bergfeld WF, Tuthill RJ (1993) Malignant melanoma arising in a blue nevus with features of pilar neurocristic hamartoma. J Cutan Pathol 20:459-464
103. Pearson JP, Weiss SW, Headington JT (1996) Cutaneous malignant melanotic neurocristic tumors arising in neurocristic hamartomas. A melanocytic tumor morphologically and biologically distinct from common melanoma. Am J Surg Pathol 20:665-677
104. Penman HG, Stringer HC (1971) Malignant transformation in giant congenital pigmented nevus. Death in early childhood. Arch Dermatol 103:428-432
105. Pereira F, Carey W, Shibata H, Burnier MN Jr, Wang B (2002) Multiple nevoid malignant melanomas in a patient with AIDS: the role of proliferating cell nuclear antigen in the diagnosis. J Am Acad Dermatol 47:S172-S174
106. Phan A, Touzet S, Dalle S, Ronger-Savle S, Balme B, Thomas L (2003) Acral lentiginous melanoma: a clinicoprognostic study of 126 cases. Br J Dermatol 155:561-569
107. Podnos YD, Jimenez JC, Zainabadi K, Jakowatz JG, Barr RJ (2002) Minimal deviation melanoma. Cancer Treat Rev 28:219-221
108. Reed RJ, Webb SV, Clark WH Jr (1990) Minimal deviation melanoma (halo nevus variant). Am J Surg Pathol 14:53-68
109. Reed RJ (1990) Minimal deviation melanoma. Human Pathol 21:1206-1211
110. Reed RJ, Martin P (1997) Variants of melanoma. Semin Cutan Med Surg 16:137-158
111. Reed RJ (1999) Atypical spitz nevus/tumor. Human Pathol 30:1523-1526
112. Reed RJ (2000) Minimal deviation melanoma. Borderline and intermediate melanocytic neoplasia. Clin Lab Med 20:745-758
113. Requena C, Requena L, Sanchez-Yus E, Nagore E, Alfaro A, Llombart B, Botella R, Sanmartin O, Guillen C (2006) Pigmented epithelioid Spitz naevus: report of two cases. Histopathology 49:549-551
114. Requena L, Sanchez Yus E (1990) Pigmented spindle cell naevus. Br J Dermatol 123:757-763
115. Richardson SK, Tannous ZS, Mihm MC Jr (2002) Congenital and infantile melanoma: review of the literature and report of an uncommon variant, pigment-synthesizing melanoma. J Am Acad Dermatol 47:77-90
116. Ridgeway CA, Hieken TJ, Ronan SG, Kim DK, Das Gupta TK (1995) Acral lentiginous melanoma. Arch Surg 130:88-92
117. Robson A, Morley-Quante M, Hempel H, McKee PH, Calonje E (2003) Deep penetrating naevus: clinicopathological study of 31 cases with further delineation of histological features allowing distinction from other pigmented benign melanocytic lesions and melanoma. Histopathology 43:529-537
118. Rongioletti F, Ball RA, Marcus R, Barnhill RL (2000) Histopathological features of flexural melanocytic nevi: a study of 40 cases. J Cutan Pathol 27:215-217
119. Rose C, Kaddu S, El-Sherif TF, Kerl H (2003) A distinctive type of widespread congenital melanocytic nevus with large nodules. J Am Acad Dermatol 49:732-735
120. Roth MJ, Medeiros LJ, Kapur S, Wexler LH, Mims S, Horowitz ME, Tsokos M (1993) Malignant schwannoma with melanocytic and neuroepithelial differentiation in an infant with congenital giant melanocytic nevus: a complex neurocristopathy. Human Pathol 24:1371-1375
121. Rudolph P, Lappe T, Schubert C, Schmidt D, Parwaresch RM, Christophers E (1995) Diagnostic assessment of two novel proliferation-specific antigens in benign and malignant melanocytic lesions. Am J Pathol 147(6):1615-1625
122. Rudolph P, Schubert C, Schubert B, Parwaresch R (1997) Proliferation marker Ki-S5 as a diagnostic tool in melanocytic lesions. J Am Acad Dermatol 37(2 Pt 1):169-178
123. Sachdeva M, Frambach GE, Crowson AN, Deng AC, Mihm MC Jr, Magro CM (2005) De novo intraepidermal epithelioid melanocytic dysplasia as a marker of the atypical mole phenotype-a clinical and pathological study of 75 patients. J Cutan Pathol 32:622-628
124. Saida T, Yoshida N (1990) Guidelines for histopathologic diagnosis of plantar malignant melanoma. Two-dimensional coordination of maximum diameters of lesions and degrees of intraepidermal proliferation of melanocytes. Dermatologica 181:112-116
125. Sau P, Graham JH, Helwig EB (1993) Pigmented spindle cell nevus: a clinicopathologic analysis of ninety-five cases. J Am Acad Dermatol 28:565-571
126. Scalzo DA, Hida CA, Toth G, Sober AJ, Mihm MC Jr (1997) Childhood melanoma: a clinicopathological study of 22 cases. Melanoma Res 7:63-68
127. Schmoeckel C, Castro CE, Braun-Falco O (1985) Nevoid malignant melanoma. Arch Dermatol Res 277:362-369
128. Scolyer RA, Thompson JF, Warnke K, McCarthy SW (2004) Pigmented epithelioid melanocytoma. Am J Surg Pathol 28:1114-1115
129. Scrivner D, Oxenhandler RW, Lopez M, Perez-Mesa C (1987) Plantar lentiginous melanoma. A clinicopathologic study. Cancer 1987(60):2502-2509
130. Shaw HM, McCarthy WH (1997) Concerning small-diameter invasive melanoma. J Cutan Pathol 24:261-262
131. Signoretti S, Annessi G, Puddu P, Faraggiana T (1999) Melanocytic nevi of palms and soles: a histological study according to the plane of section. Am J Surg Pathol 23:283-287
132. Smith KJ, Barrett TL, Skelton HG 3rd, Lupton GP, Graham JH (1989) Spindle cell and epithelioid cell nevi with atypia and metastasis (malignant Spitz nevus). Am J Surg Pathol 13:931-939
133. Smith KJ, Mezebish D, Williams J, Elgart ML, Skelton HG (1998) The spectrum of neurocristic cutaneous hamartoma: clinicopathologic and immunohistochemical study of three cases. Ann Diagn Pathol 2:213-223
134. Smith NP (1987) The pigmented spindle cell tumor of Reed: an underdiagnosed lesion. Semin Diagn Pathol 4:75-87
135. Sordi E, Ferrari A, Piccolo D, Peris K (2002) Pigmented Spitz nevi. Dermatol Surg 28:1182-1183
136. Spatz A, Ruiter D, Hardmeier T, Renard N, Wechsler J, Bailly C, Avril MF, Kwee H, Bastian BC, Hill C, De Potter C, Prade M (1996) Melanoma in childhood: an EORTC-MCG multicenter study on the clinico-pathological aspects. Int J Cancer 68:317-324
137. Stalkup JR, Orengo IF, Katta R (2002) Controversies in acral lentiginous melanoma. Dermatol Surg 28:1051-1059
138. Stas M, van den Oord JJ, Garmyn M, Degreef H, De Wever I, De Wolf-Peeters C (2000) Minimal deviation and/or naevoid melanoma: is recognition worthwhile? A clinicopathological study of nine cases. Melanoma Res 10:371-380
139. Su LD, Fullen DR, Sondak VK, Johnson TM, Lowe L (2003) Sentinel lymph node biopsy for patients with problematic spitzoid melanocytic lesions: a report on 18 patients. Cancer 97:499-507
140. Takata M, Maruo K, Kageshita T, Ikeda S, Ono T, Shirasaki F, Takehara K, Bastian BC (2003) Two cases of unusual acral melanocytic tumors: illustration of molecular cytogenetics as a diagnostic tool. Human Pathol 34:89-92
141. Temple-Camp CR, Saxe N, King H (1988) Benign and malignant cellular blue nevus. A clinicopathological study of 30 cases. Am J Dermatopathol 10:289-296
142. Tomizawa K (2002) Desmoplastic Spitz nevus showing vascular proliferation more prominently in the deep portion. Am J Dermatopathol 24:184-185
143. Tran TA, Carlson JA, Basaca PC, Mihm MC (1998) Cellular blue nevus with atypia (atypical cellular blue nevus): a clinicopathologic study of nine cases. J Cutan Pathol 25:252-258
144. Troxel DB (2003) Pitfalls in the diagnosis of malignant melanoma: findings of a risk management panel study. Am J Surg Pathol 27:1278-1283
145. Troxel DB (2006) Medicolegal aspects of error in pathology. Arch Pathol Lab Med 130:617-619
146. Vollmer RT (1987) Minimal deviation melanoma. Human Pathol 18:869-870
147. Vollmer RT (2004) Patient age in Spitz nevus and malignant melanoma: implication of Bayes rule for differential diagnosis. Am J Clin Pathol 121:872-877
148. Vollmer RT (2004) Use of Bayes rule and MIB-1 proliferation index to discriminate Spitz nevus from malignant melanoma. Am J Clin Pathol 122:499-505
149. Walsh NM, Roberts JT, Orr W, Simon GT (1988) Desmoplastic malignant melanoma. A clinicopathologic study of 14 cases. Arch Pathol Lab Med 112:922-927
150. Walsh N, Crotty K, Palmer A, McCarthy S (1998) Spitz nevus versus spitzoid malignant melanoma: an evaluation of the current distinguishing histopathologic criteria. Human Pathol 29:1105-1112
151. Ward JR, Brady SP, Tada H, Levin NA (2006) Pigmented epithelioid melanocytoma. Int J Dermatol 45:1403-1405
152. Wick MR, Swanson PE, Rocamora A (1988) Recognition of malignant melanoma by monoclonal antibody HMB-45. An immunohistochemical study of 200 paraffin-embedded cutaneous tumors. J Cutan Pathol 15:201-207
153. Wick MR (2006) Melanocytic lesions with features of Spitz nevus. Human Pathol 37:779-780
154. Wong TY, Suster S, Duncan LM, Mihm MC Jr (1995) Nevoid melanoma: a clinicopathological study of seven cases of malignant melanoma mimicking spindle and epithelioid cell nevus and verrucous dermal nevus. Human Pathol 26:171-179
155. Xu X, Bellucci KS, Elenitsas R, Elder DE (2004) Cellular nodules in congenital pattern nevi. J Cutan Pathol 31:153-159
156. Xu X, Elder DE (2004) A practical approach to selected problematic melanocytic lesions. Am J Clin Pathol 121:S3-S32
157. Yasaka N, Furue M, Tamaki K (1995) Histopathological evaluation of halo phenomenon in Spitz nevus. Am J Dermatopathol 17:484-486
158. Zembowicz A, McCusker M, Chiarelli C, Dei Tos AP, Granter SR, Calonje E, McKee PH (2001) Morphological analysis of nevoid melanoma: a study of 20 cases with a review of the literature. Am J Dermatopathol 23:167-175
159. Zembowicz A, Granter SR, McKee PH, Mihm MC (2002) Amelanotic cellular blue nevus: a hypopigmented variant of the cellular blue nevus: clinicopathologic analysis of 20 cases. Am J Surg Pathol 26:1493-1500
160. Zembowicz A, Mihm MC (2004) Dermal dendritic melanocytic proliferations: an update. Histopathology 45:433-451
161. Zembowicz A, Carney JA, Mihm MC (2004) Pigmented epithelioid melanocytoma: a low-grade melanocytic tumor with metastatic potential indistinguishable from animal-type melanoma and epithelioid blue nevus. Am J Surg Pathol 28:31-40